estrone has been researched along with Hypospadias in 4 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
Hypospadias: A birth defect due to malformation of the URETHRA in which the urethral opening is below its normal location. In the male, the malformed urethra generally opens on the ventral surface of the PENIS or on the PERINEUM. In the female, the malformed urethral opening is in the VAGINA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined associations between urinary phthalate metabolite concentrations in early pregnancy and serum free testosterone (FT), TT, estrone (E1), and estradiol (E2) in 591 woman/infant dyads in The Infant Development and Environment Study; we also examined relationships between hormones and newborn genital outcomes using multiple regression models with covariate adjustment." | 3.85 | Early Prenatal Phthalate Exposure, Sex Steroid Hormones, and Birth Outcomes. ( Barrett, E; Butts, S; Haaland, W; Nguyen, R; Sathyanarayana, S; Schwartz, SM; Swan, SH; Wang, C, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sathyanarayana, S | 1 |
| Butts, S | 1 |
| Wang, C | 1 |
| Barrett, E | 1 |
| Nguyen, R | 1 |
| Schwartz, SM | 1 |
| Haaland, W | 1 |
| Swan, SH | 1 |
| Walsh, PC | 1 |
| Madden, JD | 1 |
| Harrod, MJ | 2 |
| Goldstein, JL | 2 |
| MacDonald, PC | 2 |
| Wilson, JD | 2 |
| Knorr, D | 1 |
| Bidlingmaier, F | 1 |
| Engelhardt, D | 1 |
| Hemsell, DL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy[NCT04288427] | 120 participants (Anticipated) | Interventional | 2020-09-25 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for estrone and Hypospadias
| Article | Year |
|---|---|
Early Prenatal Phthalate Exposure, Sex Steroid Hormones, and Birth Outcomes.
Topics: Adult; Chromatography, Liquid; Cryptorchidism; Disorders of Sex Development; Estradiol; Estrone; Fem | 2017 |
Familial incomplete male pseudohermaphroditism, type 2. Decreased dihydrotestosterone formation in pseudovaginal perineoscrotal hypospadias.
Topics: Abdomen; Adolescent; Androstenedione; Child, Preschool; Culture Techniques; Dihydrotestosterone; Dis | 1974 |
Reifenstein's syndrome, a 17beta-hydroxysteroid-oxydoreductase deficiency?
Topics: Androstenedione; Child; Disorders of Sex Development; Estradiol; Estrone; Follicle Stimulating Hormo | 1973 |
Familial incomplete male pseudohermaphroditism, type 1. Evidence for androgen resistance and variable clinical manifestations in a family with the Reifenstein syndrome.
Topics: Adolescent; Adult; Androgen-Insensitivity Syndrome; Androgens; Androstenedione; Child; Child, Presch | 1974 |