Page last updated: 2024-11-07

estrone and Hypogonadism

estrone has been researched along with Hypogonadism in 38 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Hypogonadism: Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).

Research Excerpts

ExcerptRelevanceReference
"Oleoyl-estrone (OE) has been presented as a potential antiobesity therapeutic, but the published series of studies from one laboratory has not yet been independently confirmed, and the exact mechanism of action is unknown."7.76Action profile of the antiobesity drug candidate oleoyl-estrone in rats. ( Anker, SD; Chaudhary, N; Nogueiras, R; Perez-Tilve, D; Pfluger, PT; Strassburg, S; Tschöp, MH; Tso, P, 2010)
"The purpose of this study was to evaluate, without using radioisotopes, the peripheral contribution of dehydroepiandrosterone (D) to estrogens and to androstenedione (A) in patients with hypogonadotropic hypogonadism associated with weight loss (HH) and in normal menstruating women (N)."7.67Reduced conversion of dehydroepiandrosterone into estrogens in women having hypogonadotropic hypogonadism associated with weight loss. ( Bolelli, G; Bonavia, M; Bulletti, C; Ferraretti, AP; Flamigni, C; Franceschetti, F; Jasonni, VM, 1986)
"Hypogonadism is common in HIV-infected men."5.62Health status is related to testosterone, estrone and body fat: moving to functional hypogonadism in adult men with HIV. ( Bertani, D; Carli, F; Cuomo, G; De Santis, MC; De Vincentis, S; Decaroli, MC; Diazzi, C; Fanelli, F; Guaraldi, G; Mezzullo, M; Milic, J; Morini, F; Pagotto, U; Rochira, V; Roli, L; Santi, D; Tagliavini, S; Tartaro, G; Trenti, T, 2021)
"Oleoyl-estrone (OE) has been presented as a potential antiobesity therapeutic, but the published series of studies from one laboratory has not yet been independently confirmed, and the exact mechanism of action is unknown."3.76Action profile of the antiobesity drug candidate oleoyl-estrone in rats. ( Anker, SD; Chaudhary, N; Nogueiras, R; Perez-Tilve, D; Pfluger, PT; Strassburg, S; Tschöp, MH; Tso, P, 2010)
"The purpose of this study was to evaluate, without using radioisotopes, the peripheral contribution of dehydroepiandrosterone (D) to estrogens and to androstenedione (A) in patients with hypogonadotropic hypogonadism associated with weight loss (HH) and in normal menstruating women (N)."3.67Reduced conversion of dehydroepiandrosterone into estrogens in women having hypogonadotropic hypogonadism associated with weight loss. ( Bolelli, G; Bonavia, M; Bulletti, C; Ferraretti, AP; Flamigni, C; Franceschetti, F; Jasonni, VM, 1986)
"oestrone, oestradiol-17beta and testosterone in serum were measured during a LH-RH infusion test and a Leydig cell function test with HCG in healthy men and in patients with primary or secondary hypogonadism."3.65Oestrone, oestradiol and testosterone in normal and hypogonadal men following LH-RH or HCG stimulation. ( Kley, HK; Krüskemper, HL; Nieschlag, E; Wiegelmann, W, 1976)
"Oestrone (E1), oestradiol (E2), testosterone (T), androstenedione (A) and cortisol (F) as well as LH and the percentage of binding of E1, E2, T and F in plasma were measured and compared in normal young and old male subjects and in male patients with fatty liver, chronic hepatitis and cirrhosis of the liver."3.65Steroid hormones and their binding in plasma of male patients with fatty liver, chronic hepatitis and liver cirrhosis. ( Kley, HK; Krüskemper, HL; Nieschlag, E; Solbach, HG; Wiegelmann, W, 1975)
"Hypogonadism is common in HIV-infected men."1.62Health status is related to testosterone, estrone and body fat: moving to functional hypogonadism in adult men with HIV. ( Bertani, D; Carli, F; Cuomo, G; De Santis, MC; De Vincentis, S; Decaroli, MC; Diazzi, C; Fanelli, F; Guaraldi, G; Mezzullo, M; Milic, J; Morini, F; Pagotto, U; Rochira, V; Roli, L; Santi, D; Tagliavini, S; Tartaro, G; Trenti, T, 2021)
"Fourteen of them were affected by hypogonadotropic hypogonadism (11 with thalassemia major, 3 with multiple pituitary hormone deficiency), the 15th patient had an asymmetric gonadal dysgenesis (karyotype 45, X 0/46, XY)."1.28Transdermal estradiol substitution therapy for the induction of puberty in female hypogonadism. ( Bozzola, M; Cisternino, M; Grignani, G; Nahoul, K; Perani, G; Roger, M; Sampaolo, P; Severi, F, 1991)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199029 (76.32)18.7374
1990's3 (7.89)18.2507
2000's1 (2.63)29.6817
2010's4 (10.53)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
De Vincentis, S1
Decaroli, MC1
Fanelli, F1
Diazzi, C1
Mezzullo, M1
Morini, F1
Bertani, D1
Milic, J1
Carli, F1
Cuomo, G1
Santi, D1
Tartaro, G1
Tagliavini, S1
De Santis, MC1
Roli, L1
Trenti, T1
Pagotto, U1
Guaraldi, G1
Rochira, V1
Savkovic, S1
Lim, S1
Jayadev, V1
Conway, A1
Turner, L1
Curtis, D1
Goebel, C1
Handelsman, DJ1
Giton, F1
Trabado, S1
Maione, L1
Sarfati, J1
Le Bouc, Y1
Brailly-Tabard, S1
Fiet, J1
Young, J1
Rech, CM1
Clapauch, R1
de Souza, Md1
Bouskela, E1
Strassburg, S1
Pfluger, PT1
Chaudhary, N1
Tso, P1
Tschöp, MH1
Anker, SD1
Nogueiras, R1
Perez-Tilve, D1
KELLY, LW1
LIPSETT, MB1
KORENMAN, SG1
WOTIZ, HH1
STEWART, WK1
FLEMING, LW1
ROLLA, M1
PANICUCCI, F1
GAMBASSI, G1
Zumoff, B2
Miller, LK2
Strain, GW2
Martin, FI1
Frick, J1
Bende, T1
Aulitzky, H1
Schmidt, F1
Reiter, EO1
Duckett, GE1
Root, AW1
Bahnsen, M1
Gluud, C1
Johnsen, SG1
Bennett, P1
Svenstrup, S1
Micic, S1
Dietrichson, O1
Svendsen, LB1
Brodthagen, UA1
Hirai, M1
Masubuchi, Y1
Komoriyama, K1
Wang, C1
Paulsen, CA1
Hopper, BR1
Rebar, RW1
Yen, SS2
Finkelstein, JW1
Susman, EJ1
Chinchilli, VM1
Kunselman, SJ1
D'Arcangelo, MR1
Schwab, J1
Demers, LM1
Liben, LS1
Lookingbill, G1
Kulin, HE1
Sizonenko, PC1
Gordon, GG1
Southren, AL1
Lieber, CS1
Kley, HK3
Nieschlag, E3
Wiegelmann, W3
Krüskemper, HL3
Van Thiel, DH1
Lester, R1
Smith, SR1
Chhetri, MK1
Johanson, J1
Radfar, N1
Migeon, CJ1
Solbach, HG1
Cisternino, M1
Nahoul, K1
Bozzola, M1
Grignani, G1
Perani, G1
Sampaolo, P1
Roger, M1
Severi, F1
Stuenkel, CA1
Dudley, RE1
Bulletti, C1
Jasonni, VM1
Bolelli, G1
Franceschetti, F1
Ferraretti, AP1
Bonavia, M1
Flamigni, C1
Schwarz, HP1
Zimmermann, A1
Carasso, A1
Zuppinger, K1
Rosner, W1
Levit, CD1
Miller, EH1
Rosenfeld, RS1
Myking, O1
Aakvaag, A1
Digranes, O1
Veldhuis, JD1
Sowers, JR1
Rogol, AD1
Klein, FA1
Miller, N1
Dufau, ML1
Schmidt, H1
Starcevic, Z1
Krese, A1
Conti, C1
Sciarra, F3
Concolino, G3
Marocchi, A3
Sorcini, G2
Epstein, BJ1
Raheja, MC1
Frow, E1
Morse, WI1

Reviews

5 reviews available for estrone and Hypogonadism

ArticleYear
ANDROGEN METABOLISM.
    JAMA, 1964, Nov-23, Volume: 190

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Androsterone; Blood; Chorionic Go

1964
[Endocrino-pharmacological study of reproduction: Role and biosynthesis of steroid hormones in the feto-placental unit].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1981, Volume: 77, Issue:3

    Topics: Androgens; Corpus Luteum; Estradiol; Estriol; Estrogens; Estrone; Female; Fetal Diseases; Fetus; Hum

1981
Endocrine laboratory findings in pubertal distrubances.
    Clinics in endocrinology and metabolism, 1975, Volume: 4, Issue:1

    Topics: Adolescent; Adrenal Glands; Adult; Age Factors; Androstenedione; Child; Child, Preschool; Clomiphene

1975
Alcoholism: its effect on hypothalamic pituitary gonadal function.
    Gastroenterology, 1976, Volume: 71, Issue:2

    Topics: Alcoholism; Animals; Chronic Disease; Estrogens; Estrone; Feminization; Gonadotropins, Pituitary; Go

1976
[Liver cirrhosis and hyperestrogenism].
    Deutsche medizinische Wochenschrift (1946), 1976, Aug-27, Volume: 101, Issue:35

    Topics: Adult; Aged; Chemical Phenomena; Chemistry; Estradiol; Estrogens; Estrone; Fatty Liver; Gynecomastia

1976

Trials

2 trials available for estrone and Hypogonadism

ArticleYear
Reversal of the hypogonadotropic hypogonadism of obese men by administration of the aromatase inhibitor testolactone.
    Metabolism: clinical and experimental, 2003, Volume: 52, Issue:9

    Topics: Adult; Aromatase Inhibitors; Body Mass Index; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Foll

2003
Estrogen or testosterone increases self-reported aggressive behaviors in hypogonadal adolescents.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:8

    Topics: Adolescent; Adult; Aggression; Child; Cross-Over Studies; Double-Blind Method; Estrogens, Conjugated

1997

Other Studies

31 other studies available for estrone and Hypogonadism

ArticleYear
Health status is related to testosterone, estrone and body fat: moving to functional hypogonadism in adult men with HIV.
    European journal of endocrinology, 2021, Volume: 184, Issue:1

    Topics: Absorptiometry, Photon; Adipose Tissue; Adult; Antiretroviral Therapy, Highly Active; Body Compositi

2021
Urine and Serum Sex Steroid Profile in Testosterone-Treated Transgender and Hypogonadal and Healthy Control Men.
    The Journal of clinical endocrinology and metabolism, 2018, 06-01, Volume: 103, Issue:6

    Topics: Adolescent; Adult; Androgens; Androsterone; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol;

2018
Sex steroids, precursors, and metabolite deficiencies in men with isolated hypogonadotropic hypogonadism and panhypopituitarism: a GCMS-based comparative study.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:2

    Topics: Adult; Androstenedione; Chromatography, Gas; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol;

2015
Low testosterone levels are associated with endothelial dysfunction in oophorectomized early postmenopausal women.
    European journal of endocrinology, 2016, Volume: 174, Issue:3

    Topics: Absorptiometry, Photon; Androstenedione; Blood Glucose; Case-Control Studies; Cholesterol; Cholester

2016
Action profile of the antiobesity drug candidate oleoyl-estrone in rats.
    Obesity (Silver Spring, Md.), 2010, Volume: 18, Issue:12

    Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Arcuate Nucleus of Hypothalamus; Body Fluid Compartmen

2010
Ovarian dwarfism with pituitary tumor.
    The Journal of clinical endocrinology and metabolism, 1963, Volume: 23

    Topics: Dwarfism; Estrone; Humans; Hypogonadism; Norethynodrel; Pituitary Neoplasms; Turner Syndrome

1963
THE FEMINIZING SYNDROME IN MALE SUBJECTS WITH ADRENOCORTICAL NEOPLASMS.
    The American journal of medicine, 1964, Volume: 37

    Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenogenital Syndrome; Estradiol; Estriol; Estrogens; Est

1964
[THE RELATIONSHIP BETWEEN VAGINAL CYTOLOGY AND ESTROGENURIA].
    Folia endocrinologica, 1964, Volume: 17

    Topics: Amenorrhea; Chromatography; Colorimetry; Cushing Syndrome; Estradiol; Estriol; Estrogens; Estrone; F

1964
The stimulation and prolonged maintenance of spermatogenesis by human pituitary gonadotrophins in a patient with hypogonadotrophic hypogonadism.
    The Journal of endocrinology, 1967, Volume: 38, Issue:4

    Topics: Adult; Chorionic Gonadotropin; Estradiol; Estriol; Estrone; Follicle Stimulating Hormone; Humans; Hy

1967
Subdermal implants of different steroidal compounds for treatment of endocrinological disorders.
    European urology, 1981, Volume: 7, Issue:2

    Topics: Adult; Aged; Drug Implants; Estrone; Ethinyl Estradiol; Female; Humans; Hypogonadism; Male; Middle A

1981
Responses to constant infusion of LH-RH in girls with primary hypogonadism.
    Obstetrics and gynecology, 1980, Volume: 56, Issue:3

    Topics: Adolescent; Adult; Androstenedione; Child; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; E

1980
Pituitary-testicular function in patients with alcoholic cirrhosis of the liver.
    European journal of clinical investigation, 1981, Volume: 11, Issue:6

    Topics: Adult; Aged; Dehydroepiandrosterone; Estradiol; Estrone; Gonadotropins; Gynecomastia; Humans; Hypogo

1981
Acute steroidogenic responsiveness to human luteinizing hormone in hypogonadotropic hypogonadism.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:6

    Topics: 17-alpha-Hydroxypregnenolone; Adult; Estradiol; Estrone; Gonadal Steroid Hormones; Humans; Hydroxypr

1980
Hypogonadism and feminization in the male: a triple effect of alcohol.
    Alcoholism, clinical and experimental research, 1979, Volume: 3, Issue:3

    Topics: Alcoholism; Estradiol; Estrone; Ethanol; Feminization; Gonadal Steroid Hormones; Humans; Hypogonadis

1979
Oestrone, oestradiol and testosterone in normal and hypogonadal men following LH-RH or HCG stimulation.
    Acta endocrinologica, 1976, Volume: 81, Issue:3

    Topics: Chorionic Gonadotropin; Color Vision Defects; Estradiol; Estrone; Eunuchism; Gonadotropin-Releasing

1976
The pituitary-gonadal axis in men with protein-calorie malnutrition.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 41, Issue:1

    Topics: Adult; Cholesterol; Chorionic Gonadotropin; Estradiol; Estrone; Follicle Stimulating Hormone; Humans

1975
Steroid hormones and their binding in plasma of male patients with fatty liver, chronic hepatitis and liver cirrhosis.
    Acta endocrinologica, 1975, Volume: 79, Issue:2

    Topics: Adult; Age Factors; Aged; Androstenedione; Chronic Disease; Estradiol; Estrone; Fatty Liver; Gynecom

1975
Transdermal estradiol substitution therapy for the induction of puberty in female hypogonadism.
    Journal of endocrinological investigation, 1991, Volume: 14, Issue:6

    Topics: Administration, Cutaneous; Adolescent; Adult; Blood Coagulation; Breast; Estradiol; Estriol; Estroge

1991
Sublingual administration of testosterone-hydroxypropyl-beta-cyclodextrin inclusion complex simulates episodic androgen release in hypogonadal men.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:5

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Sublingual; Adult; Androgens; Androstenedione; be

1991
Reduced conversion of dehydroepiandrosterone into estrogens in women having hypogonadotropic hypogonadism associated with weight loss.
    Journal of steroid biochemistry, 1986, Volume: 24, Issue:6

    Topics: Adult; Amenorrhea; Androstenedione; Body Weight; Dehydroepiandrosterone; Dehydroepiandrosterone Sulf

1986
Feminization in a galactosemic girl in the presence of hypergonadotropic hypogonadism.
    Acta endocrinologica. Supplementum, 1986, Volume: 279

    Topics: Adult; Amenorrhea; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Estrone; Femal

1986
Partial reversal of the hypogonadotropic hypogonadism of obese men by administration of corticosuppressive doses of dexamethasone.
    International journal of obesity, 1988, Volume: 12, Issue:6

    Topics: Adult; Androstenedione; Dexamethasone; Estradiol; Estrone; Follicle Stimulating Hormone; Humans; Hyp

1988
Androgen-oestrogen imbalance in men with chronic alcoholism and fatty liver.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1987, Volume: 22, Issue:1

    Topics: Adult; Aged; Androgens; Estradiol; Estrogens; Estrone; Fatty Liver, Alcoholic; Feminization; Humans;

1987
Pathophysiology of male hypogonadism associated with endogenous hyperestrogenism. Evidence for dual defects in the gonadal axis.
    The New England journal of medicine, 1985, May-23, Volume: 312, Issue:21

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Neoplasms; Carcinoma; Estradiol; Estrogens; Estrone; Fe

1985
[The diagnostic significance of testosterone, 17-ketosteroids and estrogen secretion in male hypogonadism].
    Klinische Wochenschrift, 1965, Dec-01, Volume: 43, Issue:23

    Topics: Adult; Androsterone; Animals; Castration; Chromatography; Dehydroepiandrosterone; Estradiol; Estriol

1965
[Steroid spectrum of diabetic men in relationship to their potency].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1966, Oct-01, Volume: 21, Issue:19

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Androsterone; Cortisone; Dehydroepiandrosterone;

1966
Two cases of germinal aplasia: plasma concentration and in vitro biosynthesis of androgens.
    Folia endocrinologica, 1968, Volume: 21, Issue:4

    Topics: 17-Ketosteroids; Adult; Androgens; Carbon Isotopes; Dehydroepiandrosterone; Eczema; Estradiol; Estro

1968
A simple procedure for the combined determination of plasma estrogen and androgen concentrations by competitive protein binding analysis.
    Journal of steroid biochemistry, 1972, Volume: 3, Issue:4

    Topics: Adult; Androstenes; Animals; Binding, Competitive; Blood Proteins; Castration; Chromatography; Chrom

1972
[Aspects of the metabolism of androgen and estrogen hormones in humans. 3. The metabolic clearance rate and hematic production rate of estradiol in hypogonadal subjects].
    Folia endocrinologica, 1971, Volume: 24, Issue:1

    Topics: Adult; Androgens; Estradiol; Estrogens; Estrone; Humans; Hypogonadism; Male; Metabolic Clearance Rat

1971
[Aspects of metabolism of androgenic and estrogenic hormones in man. IV. Evaluation of the testosterone conversion factor in estradiol in hypogonadal subjects].
    Folia endocrinologica, 1971, Volume: 24, Issue:2

    Topics: Adult; Androgens; Estradiol; Estrogens; Estrone; Gonads; Humans; Hypogonadism; Liver; Male; Middle A

1971
Estrogen synthesis in normal and hypogonadal men. Quantitative studies on the precursor role of testosterone.
    Canadian journal of biochemistry, 1966, Volume: 44, Issue:6

    Topics: 17-Ketosteroids; Adult; Castration; Chromatography, Paper; Estradiol; Estriol; Estrogens; Estrone; H

1966