Page last updated: 2024-11-07

estrone and Hemorrhage, Uterine

estrone has been researched along with Hemorrhage, Uterine in 38 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Research Excerpts

ExcerptRelevanceReference
"5 mg medroxyprogesterone acetate (MPA) on GnRH agonists (GnRH-a) treatment in Japanese women with symptomatic endometriosis."9.09Efficacy of every-other-day administration of conjugated equine estrogen and medroxyprogesterone acetate on gonadotropin-releasing hormone agonists treatment in women with endometriosis. ( Aono, T; Irahara, M; Kamada, M; Kinoshita, H; Kiyokawa, M; Tezuka, M; Uemura, H; Yamada, M; Yasui, T, 2001)
"Plasma androstenedione (A) levels and plasma oestrone (E1) levels were measured by radioimmunoassay in a total of 135 healthy women (the control group), around the menopause."7.66Plasma androstenedione and oestrone levels before and after the menopause. I. Glandular hyperplasia and adenocarcinoma of the endometrium. ( Battaglia, F; Mango, D; Montemurro, A; Scirpa, P; Scirpa, S, 1982)
"5 mg medroxyprogesterone acetate (MPA) on GnRH agonists (GnRH-a) treatment in Japanese women with symptomatic endometriosis."5.09Efficacy of every-other-day administration of conjugated equine estrogen and medroxyprogesterone acetate on gonadotropin-releasing hormone agonists treatment in women with endometriosis. ( Aono, T; Irahara, M; Kamada, M; Kinoshita, H; Kiyokawa, M; Tezuka, M; Uemura, H; Yamada, M; Yasui, T, 2001)
"Plasma androstenedione (A) levels and plasma oestrone (E1) levels were measured by radioimmunoassay in a total of 135 healthy women (the control group), around the menopause."3.66Plasma androstenedione and oestrone levels before and after the menopause. I. Glandular hyperplasia and adenocarcinoma of the endometrium. ( Battaglia, F; Mango, D; Montemurro, A; Scirpa, P; Scirpa, S, 1982)
"However, vaginal bleeding complicating this therapy is among the leading causes for its early discontinuation."2.71Vaginal ring delivering estradiol and progesterone: a possible alternative to relieve climacteric symptoms. ( Ben-Chetrit, A; Gelber, H; Hochner-Celnikier, D; Lindenberg, T; Shimonovitz, S; Spitz, IM; Zacut, D, 2005)
"Any vaginal bleeding was recorded by patients in a daily diary, and endometrial biopsies were performed at entry into the study and at 3, 12, and 24 months."2.69Bleeding pattern and endometrial changes during continuous combined hormone replacement therapy. The Ogen/Provera Study Group. ( Baber, R; Nand, SL; O'Connor, V; Webster, MA, 1998)
"This pilot study was conducted to establish the optimum oral dosage of medroxyprogesterone acetate (Provera) given daily in combination with a fixed dose of piperazine oestrone sulphate (Ogen), as hormone replacement therapy."2.68Continuous combined piperazine oestrone sulphate and medroxyprogesterone acetate hormone replacement therapy--a study of bleeding pattern, endometrial response, serum lipid and bone density changes. ( Nand, SL; Webster, MA; Wren, BG, 1995)
"The ethinyl estradiol advantage was marginal, however."2.68Clinical evaluation of the therapeutic effectiveness of ethinyl oestradiol and oestrone sulphate on prolonged bleeding in women using depot medroxyprogesterone acetate for contraception. World Health Organization, Special Programme of Research, Developmen ( Affandi, B; Belsey, EM; d'Arcangues, C; Dusitsin, N; Hadisaputra, W; Kazi, A; Kirwat, O; Koetsawang, S; Noonan, E; Olayinka, I; Pinol, A; Piya-Anant, M; Ramos, RM; Rocca, M; Sadek, W; Said, S; Sethavanich, S, 1996)
"The prognosis of threatened abortion can be made by a urinary PDG/C ratio but not by an E1C/C ratio."1.27Urinary pregnandiol-3-glucuronide and estrone conjugates to creatinine ratios in early pregnancies complicated by vaginal bleeding. ( Davidson, BJ, 1986)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199025 (65.79)18.7374
1990's7 (18.42)18.2507
2000's6 (15.79)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ZONDEK, B1
ROZIN, S1
Yildirim, M1
Oktem, M1
Dilek, TU1
RAMOS, AV1
PEANO, M1
COUTINHO, S1
MARCONDES, N1
MELIN, A1
TOJO, N1
ZOLCINSKI, A1
ROBACZYNSKI, J1
HAEHNEL, R1
MARTIN, JD1
PLUNKETT, ER1
Raynaud, JP1
Lévrier, M1
Calaf, J1
Laur, C1
Pélissier, C1
Ben-Chetrit, A1
Hochner-Celnikier, D1
Lindenberg, T1
Zacut, D1
Shimonovitz, S1
Gelber, H1
Spitz, IM1
Goldzieher, JW1
Fariss, B1
Jalůvka, V1
Kratzsch, E1
von Holst, T1
Klinga, K1
Runnebaum, B1
Scirpa, P1
Mango, D1
Battaglia, F1
Scirpa, S1
Montemurro, A1
Yasui, T2
Uemura, H2
Yoneda, N1
Irahara, M2
Aono, T2
Sunahara, S1
Hata, K1
Nand, SL2
Webster, MA2
Wren, BG1
AinMelk, Y1
Said, S1
Sadek, W1
Rocca, M1
Koetsawang, S1
Kirwat, O1
Piya-Anant, M1
Dusitsin, N1
Sethavanich, S1
Affandi, B1
Hadisaputra, W1
Kazi, A1
Ramos, RM1
d'Arcangues, C1
Belsey, EM1
Noonan, E1
Olayinka, I1
Pinol, A1
Ross, D1
Cooper, AJ1
Pryse-Davies, J1
Bergeron, C1
Collins, WP1
Whitehead, MI1
Hirvonen, E1
Cacciatore, B1
Wahlström, T1
Rita, H1
Wilén-Rosenqvist, G1
Baber, R1
O'Connor, V1
Byrjalsen, I1
Alexandersen, P1
Christiansen, C1
Kinoshita, H1
Yamada, M1
Tezuka, M1
Kiyokawa, M1
Kamada, M1
Rebar, RW1
Trabal, J1
Mortola, J1
Badawy, SZ1
Elliott, LJ1
Elbadawi, A1
Marshall, LD1
Gambrell, RD2
MacDonald, PC1
Grodin, JM1
Edman, CD1
Vellios, F1
Siiteri, PK1
Davidson, BJ1
Schane, HP1
Anzalone, AJ1
Potts, GO1
Hamada, H1
Widholm, O1
Vartiainen, E1
Fraser, IS2
Baird, DT2
Michie, EA1
Wide, L1
Aronovich, AS1
Manuilova, IA1
Grudzień, M1
Baudet, JH1
Béguin, F1
Keller, M1
Stamm, O1
Zarro, D1
Giorgi, EP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Study of Femring Estrogen Supplementation During Depo-Provera Initiation[NCT00563576]71 participants (Actual)Interventional2007-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Mean Number of Bleeding or Spotting Days

Bleeding and spotting were defined using World Health Organization criteria and measured through daily diaries given to participants and collected at the 3 and 6 month followup. In addition, a study staff member called participants weekly to collect the daily bleeding and spotting calendar for that week to optimize the accuracy of this information. (NCT00563576)
Timeframe: 3 months

Interventiondays (Mean)
Femring16
Depot Medroxyprogesterone Acetate (DMPA) Alone28

Number of Subjects Who Receive a 2nd Injection of Depo-Provera

(NCT00563576)
Timeframe: 3 months

Interventionparticipants (Number)
Femring20
Depot Medroxyprogesterone Acetate (DMPA) Alone16

Percentage of Subjects Who Receive a 3rd Injection

(NCT00563576)
Timeframe: 6 months

InterventionParticipants (Count of Participants)
Femring13
Depot Medroxyprogesterone Acetate (DMPA) Alone10

Percentage of Users Who Were Satisfied With Femring

Acceptability was measured using questionnaires that assessed satisfaction of Femring and usage of the ring. This outcome was only measured among the intervention group of women who actually were randomized to use of Femring. Acceptability of the vaginal ring was high among those in the intervention group. (NCT00563576)
Timeframe: 3 months

Interventionparticipants (Number)
Femring84

Reviews

1 review available for estrone and Hemorrhage, Uterine

ArticleYear
[Hormone activity of various Brenner tumors].
    Gynakologische Rundschau, 1982, Volume: 22, Issue:1

    Topics: Aged; Breast Neoplasms; Brenner Tumor; Estradiol; Estrone; Female; Humans; Neoplasm Metastasis; Neop

1982

Trials

12 trials available for estrone and Hemorrhage, Uterine

ArticleYear
Comparison of the efficacy and tolerability of a new once-a-week matricial estradiol transdermal system (Estrapatch 40 and Estrapatch 60) with a twice week system.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 93, Issue:2-5

    Topics: Administration, Cutaneous; Adult; Aged; Drug Administration Schedule; Endometrium; Erythema; Estradi

2005
Vaginal ring delivering estradiol and progesterone: a possible alternative to relieve climacteric symptoms.
    The Israel Medical Association journal : IMAJ, 2005, Volume: 7, Issue:5

    Topics: Adult; Aged; Biopsy; Contraceptive Devices, Female; Dose-Response Relationship, Drug; Drug Delivery

2005
Continuous combined piperazine oestrone sulphate and medroxyprogesterone acetate hormone replacement therapy--a study of bleeding pattern, endometrial response, serum lipid and bone density changes.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1995, Volume: 35, Issue:1

    Topics: Administration, Oral; Bone Density; Drug Therapy, Combination; Endometrium; Estrogen Replacement The

1995
Comparison of two continuous combined estrogen progestogen regimens in postmenopausal women: a randomized trial.
    Fertility and sterility, 1996, Volume: 66, Issue:6

    Topics: Blood Pressure; Drug Combinations; Endometrium; Estrogen Replacement Therapy; Estrogens, Conjugated

1996
Clinical evaluation of the therapeutic effectiveness of ethinyl oestradiol and oestrone sulphate on prolonged bleeding in women using depot medroxyprogesterone acetate for contraception. World Health Organization, Special Programme of Research, Developmen
    Human reproduction (Oxford, England), 1996, Volume: 11 Suppl 2

    Topics: Adolescent; Adult; Contraceptive Agents, Female; Double-Blind Method; Estradiol Congeners; Estrogens

1996
Randomized, double-blind, dose-ranging study of the endometrial effects of a vaginal progesterone gel in estrogen-treated postmenopausal women.
    American journal of obstetrics and gynecology, 1997, Volume: 177, Issue:4

    Topics: Adult; Aged; Biopsy; Dose-Response Relationship, Drug; Double-Blind Method; Endometrium; Estradiol;

1997
Effects of transdermal oestrogen therapy in postmenopausal women: a comparative study of an oestradiol gel and an oestradiol delivering patch.
    British journal of obstetrics and gynaecology, 1997, Volume: 104 Suppl 16

    Topics: Administration, Cutaneous; Aged; Bone Density; Drug Therapy, Combination; Dydrogesterone; Endometriu

1997
Bleeding pattern and endometrial changes during continuous combined hormone replacement therapy. The Ogen/Provera Study Group.
    Obstetrics and gynecology, 1998, Volume: 91, Issue:5 Pt 1

    Topics: Adult; Biopsy, Needle; Double-Blind Method; Endometrium; Estrogen Replacement Therapy; Estrogens, Co

1998
Piperazine oestrone sulphate and interrupted norethisterone: effects on the postmenopausal endometrium.
    BJOG : an international journal of obstetrics and gynaecology, 2000, Volume: 107, Issue:3

    Topics: Administration, Oral; Endometrium; Estrone; Female; Hormone Replacement Therapy; Humans; Norethindro

2000
Efficacy of every-other-day administration of conjugated equine estrogen and medroxyprogesterone acetate on gonadotropin-releasing hormone agonists treatment in women with endometriosis.
    Gynecologic and obstetric investigation, 2001, Volume: 52, Issue:4

    Topics: Adult; Animals; Bone Density; Bone Remodeling; CA-125 Antigen; Endometriosis; Estradiol; Estrogens,

2001
Low-dose esterified estrogens (0.3 mg/day): long-term and short-term effects on menopausal symptoms and quality of life in postmenopausal women.
    Climacteric : the journal of the International Menopause Society, 2000, Volume: 3, Issue:3

    Topics: Double-Blind Method; Endometrial Hyperplasia; Equilin; Estrogen Replacement Therapy; Estrone; Female

2000
The absorption of conjugated oestrogen and sodium oestrone sulphate from the vagina.
    Annales chirurgiae et gynaecologiae Fenniae, 1974, Volume: 63, Issue:3

    Topics: Aged; Estradiol; Estriol; Estrogens; Estrogens, Conjugated (USP); Estrone; Female; Humans; Menopause

1974

Other Studies

25 other studies available for estrone and Hemorrhage, Uterine

ArticleYear
Induction of uterine bleeding in amenorrhea with a single injection of precipitates of estrone and progesterone.
    The Journal of clinical endocrinology and metabolism, 1948, Volume: 8, Issue:5

    Topics: Amenorrhea; Estrogens; Estrone; Female; Gonadal Steroid Hormones; Hormones; Humans; Injections; Prog

1948
Endometrial thickness and histopathologic findings in women with postmenopausal bleeding.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2003, Volume: 80, Issue:3

    Topics: Aged; Androgens; Biopsy, Needle; Case-Control Studies; Dilatation and Curettage; Endometrium; Enzyme

2003
[Use of intravenous estrone sulfate in hemostasis in functional uterine bleeding].
    Anais brasileiros de ginecologia, 1956, Volume: 41, Issue:5

    Topics: Estrogens; Estrone; Female; Hemostasis; Humans; Menorrhagia; Metrorrhagia; Uterine Hemorrhage

1956
[ENDOCRINOLOGICAL STUDY ON THE PITUITARY-GONADAL SYSTEM, WITH SPECIAL REFERENCE TO CONDITIONS OF ANOVULATION].
    Nihon Naibunpi Gakkai zasshi, 1963, Nov-20, Volume: 39

    Topics: Amenorrhea; Anovulation; Estradiol; Estrone; Female; Gonadotropins; Gonadotropins, Pituitary; Humans

1963
[THE EVALUATION OF THE ESTROGENIC FUNCTION OF THE OVARY AFTER RADIUM THERAPY].
    Zentralblatt fur Gynakologie, 1964, Feb-08, Volume: 86

    Topics: Cell Biology; Cytodiagnosis; Estrone; Female; Humans; Ovary; Radiotherapy; Radium; Uterine Hemorrhag

1964
URINARY OESTROGEN EXCRETION IN THREATENED ABORTION.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1964, Volume: 71

    Topics: Abortion, Induced; Abortion, Spontaneous; Abortion, Threatened; Diagnosis; Estradiol; Estriol; Estro

1964
DRUGS FOR FUNCTIONAL UTERINE BLEEDING.
    Canadian Medical Association journal, 1964, Nov-28, Volume: 91

    Topics: Contraceptive Agents; Contraceptives, Oral; Diethylstilbestrol; Dosage Forms; Drug Therapy; Dydroges

1964
The polycystic ovary. VII. Intractable uterine bleeding and endometrial hyperplasia possibly related to an extraovarian source of oestrogen.
    Acta endocrinologica, 1967, Volume: 54, Issue:3

    Topics: 17-Ketosteroids; Adrenal Glands; Adult; Androgens; Chromatography; Cysts; Endometrial Hyperplasia; E

1967
Hormone levels in healthy post-menopausal women and in women with post-menopausal bleeding with or without endometrial carcinoma.
    Maturitas, 1981, Volume: 3, Issue:3-4

    Topics: Adult; Aged; Androstenedione; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Hormones; Hu

1981
Plasma androstenedione and oestrone levels before and after the menopause. I. Glandular hyperplasia and adenocarcinoma of the endometrium.
    Maturitas, 1982, Volume: 4, Issue:1

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aging; Androstenedione; Endometrial Hyperplasia; Estrone; F

1982
[Assessment of serum estrogen levels by RIA with HPLC during hormone replacement therapy].
    Nihon Sanka Fujinka Gakkai zasshi, 1995, Volume: 47, Issue:7

    Topics: Adult; Chromatography, High Pressure Liquid; Estradiol; Estrogen Replacement Therapy; Estrogens, Con

1995
Plasma levels of oestrone and oestradiol-17beta in postmenopausal women.
    British journal of obstetrics and gynaecology, 1979, Volume: 86, Issue:1

    Topics: Adult; Age Factors; Aged; Body Weight; Endometrial Hyperplasia; Estradiol; Estrogens; Estrone; Femal

1979
Postmenopausal bleeding.
    Clinics in obstetrics and gynaecology, 1977, Volume: 4, Issue:1

    Topics: Adenocarcinoma; Adrenal Glands; Androstenedione; Contraceptives, Oral; Dilatation and Curettage; End

1977
Origin of estrogen in a postmenopausal woman with a nonendocrine tumor of the ovary and endometrial hyperplasia.
    Obstetrics and gynecology, 1976, Volume: 47, Issue:6

    Topics: Androgens; Androstenedione; Castration; Cystadenoma; Endometrial Hyperplasia; Estrogens; Estrone; Fe

1976
Urinary pregnandiol-3-glucuronide and estrone conjugates to creatinine ratios in early pregnancies complicated by vaginal bleeding.
    Fertility and sterility, 1986, Volume: 46, Issue:4

    Topics: Abortion, Threatened; Creatinine; Estrone; Female; Humans; Immunoenzyme Techniques; Pregnancy; Pregn

1986
A model for the evaluation of estrogens: withdrawal bleeding in ovariectomized rhesus monkeys.
    Fertility and sterility, 1972, Volume: 23, Issue:10

    Topics: Administration, Oral; Animals; Castration; Diethylstilbestrol; Dose-Response Relationship, Drug; Est

1972
The use of premarin, conjugated estrogens-equine to control. Functional uterine bleeding and the urinary estrogen metabolism after administration.
    Bulletin of the Osaka Medical School, 1971, Volume: 17, Issue:2

    Topics: Administration, Oral; Adult; Estradiol; Estriol; Estrogens; Estrogens, Conjugated (USP); Estrone; Fe

1971
Blood production and ovarian secretion rates of estradiol-17 beta and estrone in women with dysfunctional uterine bleeding.
    The Journal of clinical endocrinology and metabolism, 1974, Volume: 39, Issue:3

    Topics: Adult; Endometrium; Estradiol; Estrone; Female; Humans; Hyperplasia; Hysterectomy; Infusions, Parent

1974
Pituitary gonadotropins and ovarian function in adolescent dysfunctional uterine bleeding.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 37, Issue:3

    Topics: Adult; Clomiphene; Estradiol; Estrogens; Estrone; Feedback; Female; Follicle Stimulating Hormone; Hu

1973
Postmenopausal bleeding.
    Journal of the American Geriatrics Society, 1974, Volume: 22, Issue:8

    Topics: Adenocarcinoma; Adrenal Glands; Estradiol; Estrogens; Estrone; Ethinyl Estradiol; Female; Humans; Me

1974
[Estrogen excretion during testosterone and progestagen therapy of dysfunctional climacteric hemorrhage].
    Sovetskaia meditsina, 1969, Volume: 32, Issue:8

    Topics: Adult; Climacteric; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Middle Aged; Progestins;

1969
[Urinary excretion of estrogens in women with bleeding during climacteric and in menopause].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1970, Volume: 25, Issue:39

    Topics: Aged; Climacteric; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Menarche; Menopause; Mens

1970
[The painful syndromes of the cycle].
    La Presse medicale, 1969, May-28, Volume: 77, Issue:26

    Topics: Adolescent; Adult; Cervix Mucus; Diuretics; Dysmenorrhea; Endometriosis; Estrone; Female; Humans; Hy

1969
[Studies concerning the action mechanism of a retrosteroid, RO 4-8347].
    Gynaecologia. International monthly review of obstetrics and gynecology. Revue internationale mensuelle d'obstetrique et de gynecologie. Monatsschrift fur Geburtshilfe und Gynakologie, 1969, Volume: 167, Issue:5

    Topics: 17-Ketosteroids; Adult; Amenorrhea; Dydrogesterone; Estradiol; Estriol; Estrone; Female; Humans; Inf

1969
Steroids in cyst fluid from ovaries of normally menstruating women and of women with functional uterine bleeding.
    Journal of reproduction and fertility, 1965, Volume: 10, Issue:3

    Topics: Adult; Androgens; Chemical Phenomena; Chemistry; Cysts; Estradiol; Estrone; Female; Humans; Hydroxyp

1965