Page last updated: 2024-11-07

estrone and Endometrioma

estrone has been researched along with Endometrioma in 34 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Endometrioma: An enlarged area of ENDOMETRIOSIS that resembles a tumor. It is usually found in the OVARY. When it is filled with old blood, it is known as a chocolate cyst.

Research Excerpts

ExcerptRelevanceReference
"5 mg medroxyprogesterone acetate (MPA) on GnRH agonists (GnRH-a) treatment in Japanese women with symptomatic endometriosis."9.09Efficacy of every-other-day administration of conjugated equine estrogen and medroxyprogesterone acetate on gonadotropin-releasing hormone agonists treatment in women with endometriosis. ( Aono, T; Irahara, M; Kamada, M; Kinoshita, H; Kiyokawa, M; Tezuka, M; Uemura, H; Yamada, M; Yasui, T, 2001)
"To evaluate the safety and efficacy of an antiprogesterone (mifepristone, RU486; Roussel-Uclaf, Romaineville, France) on endometriosis."9.08Treatment of endometriosis with the antiprogesterone mifepristone (RU486) ( Baulieu, EE; Kettel, LM; Morales, AJ; Murphy, AA; Ulmann, A; Yen, SS, 1996)
"Eighteen patients affected by laparoscopically confirmed endometriosis were randomly assigned to three different schedules of treatment with gonadotropin-releasing hormone agonist (GnRH-a) (goserelin depot formulation 3."9.07Estrogenic suppression by different administration schedules of goserelin depot for treatment of endometriosis. ( Forti, G; Magini, A; Massi, GB; Pellegrini, S; Serio, M; Tavella, K, 1993)
"Twenty-five women with regular menstruation and laparoscopically confirmed endometriosis received 100 mcg nafarelin intranasally twice daily for six months in an open study."7.69Low dose intranasal nafarelin for the treatment of endometriosis. ( Bullingham, RE; Harris, SR; Jacobson, J, 1994)
"The hormonal effects of danazol and of a long-acting gonadotropin-releasing hormone analogue (GnRH-a) were studied in women with endometriosis and those with oophorectomy."7.66Hormonal effects of danazol and medical oophorectomy in endometriosis. ( Judd, HL; Karow, WG; Meldrum, DR; Pardridge, WM; Rivier, J; Vale, W, 1983)
" Our results suggest a critical role for ER modulation and genistein bioavailability in the maintenance of the implants."5.31Pharmacologic, but not dietary, genistein supports endometriosis in a rat model. ( Cotroneo, MS; Lamartiniere, CA, 2001)
"Endometriosis is a disease of women where endometrial tissue is found growing at ectopic sites."5.29Effects of estrogen, progesterone, and methoxychlor on surgically induced endometriosis in rats. ( Cummings, AM; Metcalf, JL, 1995)
"5 mg medroxyprogesterone acetate (MPA) on GnRH agonists (GnRH-a) treatment in Japanese women with symptomatic endometriosis."5.09Efficacy of every-other-day administration of conjugated equine estrogen and medroxyprogesterone acetate on gonadotropin-releasing hormone agonists treatment in women with endometriosis. ( Aono, T; Irahara, M; Kamada, M; Kinoshita, H; Kiyokawa, M; Tezuka, M; Uemura, H; Yamada, M; Yasui, T, 2001)
"Fifty premenopausal women with endometriosis randomized to treatment with goserelin alone (Group 1) or goserelin plus 17 beta-oestradiol and medroxyprogesterone acetate (Group 2)."5.08Endocrine effects of GnRH analogue with low-dose hormone replacement therapy in women with endometriosis. ( Dowsett, M; Edmonds, DK; Howell, R; King, N, 1995)
"To evaluate the safety and efficacy of an antiprogesterone (mifepristone, RU486; Roussel-Uclaf, Romaineville, France) on endometriosis."5.08Treatment of endometriosis with the antiprogesterone mifepristone (RU486) ( Baulieu, EE; Kettel, LM; Morales, AJ; Murphy, AA; Ulmann, A; Yen, SS, 1996)
"Eighteen patients affected by laparoscopically confirmed endometriosis were randomly assigned to three different schedules of treatment with gonadotropin-releasing hormone agonist (GnRH-a) (goserelin depot formulation 3."5.07Estrogenic suppression by different administration schedules of goserelin depot for treatment of endometriosis. ( Forti, G; Magini, A; Massi, GB; Pellegrini, S; Serio, M; Tavella, K, 1993)
"The aim of the study was to evaluate local E2 and estrone (E1) concentrations in the endometrium and different types of endometriosis lesions, and to correlate them with the expression of estrogen-metabolizing enzymes."3.78Endometrial and endometriotic concentrations of estrone and estradiol are determined by local metabolism rather than circulating levels. ( Desai, R; Handelsman, DJ; Huhtinen, K; Perheentupa, A; Poutanen, M; Salminen, A; Ståhle, M, 2012)
"Twenty-five women with regular menstruation and laparoscopically confirmed endometriosis received 100 mcg nafarelin intranasally twice daily for six months in an open study."3.69Low dose intranasal nafarelin for the treatment of endometriosis. ( Bullingham, RE; Harris, SR; Jacobson, J, 1994)
"The hormonal effects of danazol and of a long-acting gonadotropin-releasing hormone analogue (GnRH-a) were studied in women with endometriosis and those with oophorectomy."3.66Hormonal effects of danazol and medical oophorectomy in endometriosis. ( Judd, HL; Karow, WG; Meldrum, DR; Pardridge, WM; Rivier, J; Vale, W, 1983)
"Endometriosis is an estrogen dependent gynecological disease associated with altered microbial phenotypes."1.62Association of microbial dynamics with urinary estrogens and estrogen metabolites in patients with endometriosis. ( Braundmeier-Fleming, A; Bremer, P; Brown, V; Cregger, M; Diaz-Sylvester, P; Groesch, K; Le, N; Loret de Mola, J; Nguyen, L; Wilson, T, 2021)
"Endometriosis is a chronic inflammatory disease in which immune response and production of estrogen in endometriotic tissues are involved in the development of the disease."1.39Interleukin-4 and prostaglandin E2 synergistically up-regulate 3β-hydroxysteroid dehydrogenase type 2 in endometrioma stromal cells. ( Akiyama, I; Harada, M; Hasegawa, A; Hirata, T; Hirota, Y; Izumi, G; Koga, K; Kozuma, S; Nagai, M; Osuga, Y; Takamura, M; Urata, Y; Yoshino, O, 2013)
"Endometriosis is known to be an estrogen-dependent disease."1.35Evaluation of estrogen treatment in an immunodeficient mouse endometriosis model. ( Colette, S; Defrère, S; Donnez, J; Loumaye, E; Lousse, JC; Van Langendonckt, A, 2009)
"Endometriosis is a common women's health problem."1.34Functional imaging of estrogen receptors with radiolabeled-GAP-EDL in rabbit endometriosis model. ( Borne, A; Kim, EE; Kohanim, S; Kurihara, H; Mawlawi, O; Oh, CS; Takahashi, N; Yang, DJ, 2007)
" Our results suggest a critical role for ER modulation and genistein bioavailability in the maintenance of the implants."1.31Pharmacologic, but not dietary, genistein supports endometriosis in a rat model. ( Cotroneo, MS; Lamartiniere, CA, 2001)
"Endometriosis is a disease of women where endometrial tissue is found growing at ectopic sites."1.29Effects of estrogen, progesterone, and methoxychlor on surgically induced endometriosis in rats. ( Cummings, AM; Metcalf, JL, 1995)
" LH-FSH basal levels, prolactin, TSH, TBG, thyroxine, cortisol, and androstenedione were not changed by either dosage or duration of danazol therapy."1.26Danazol: endocrine and endometrial effects. ( Floyd, WS, 1980)
"During a 6-month course of treatment of endometriosis with Danazol, a synthetic derivative of 17alpha-ethinyl testosterone, the following hormonal changes were found."1.25Hormonal changes associated with Danazol therapy. ( Flickinger, GL; Mikhail, G; Wood, GP; Wu, CH, 1975)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199013 (38.24)18.7374
1990's8 (23.53)18.2507
2000's6 (17.65)29.6817
2010's3 (8.82)24.3611
2020's4 (11.76)2.80

Authors

AuthorsStudies
Le, N1
Cregger, M1
Brown, V1
Loret de Mola, J1
Bremer, P1
Nguyen, L1
Groesch, K1
Wilson, T1
Diaz-Sylvester, P1
Braundmeier-Fleming, A1
Othman, ER1
Markeb, AA1
Khashbah, MY1
Abdelaal, II1
ElMelegy, TT1
Fetih, AN1
Van der Houwen, LE1
Lambalk, CB1
Mijatovic, V1
Ngueta, AD1
Roy, J1
Maltais, R1
Poirier, D1
Emond, JP1
Caron, P1
Pušić, M1
Turcotte, V1
Simonyan, D1
Vogler, A1
Osredkar, J1
Rižner, TL1
Guillemette, C1
Urata, Y1
Osuga, Y1
Akiyama, I1
Nagai, M1
Izumi, G1
Takamura, M1
Hasegawa, A1
Harada, M1
Hirata, T1
Hirota, Y1
Yoshino, O1
Koga, K1
Kozuma, S1
Thomas, MP1
Potter, BV1
Colette, S1
Defrère, S1
Lousse, JC1
Van Langendonckt, A1
Loumaye, E1
Donnez, J1
Huhtinen, K1
Desai, R1
Ståhle, M1
Salminen, A1
Handelsman, DJ1
Perheentupa, A1
Poutanen, M1
SCOTT, RB1
WHARTON, LR1
GIORGI, EP1
Takahashi, N1
Yang, DJ1
Kurihara, H1
Borne, A1
Kohanim, S1
Oh, CS1
Mawlawi, O1
Kim, EE1
Floyd, WS1
Meldrum, DR3
Pardridge, WM1
Karow, WG1
Rivier, J2
Vale, W2
Judd, HL4
Chang, RJ1
Lu, J1
Mori, T1
Nagasawa, H1
Takahashi, S1
Jacobson, J1
Harris, SR1
Bullingham, RE1
Magini, A1
Pellegrini, S1
Tavella, K1
Forti, G1
Massi, GB1
Serio, M1
Cummings, AM1
Metcalf, JL1
Howell, R1
Dowsett, M1
King, N1
Edmonds, DK1
Kettel, LM1
Murphy, AA1
Morales, AJ1
Ulmann, A1
Baulieu, EE1
Yen, SS1
Bulun, SE2
Zeitoun, KM1
Takayama, K1
Sasano, H1
Cotroneo, MS1
Lamartiniere, CA1
Irahara, M1
Uemura, H1
Yasui, T1
Kinoshita, H1
Yamada, M1
Tezuka, M1
Kiyokawa, M1
Kamada, M1
Aono, T1
Yang, S1
Fang, Z1
Gurates, B1
Tamura, M1
Zhou, J1
Sebastian, S1
Kruyver, GP1
Wood, GP1
Wu, CH1
Flickinger, GL2
Mikhail, G2
Andrews, MC1
Wentz, AC1
Surrey, ES1
Gambone, JC1
Lu, JK2
Cedars, MI1
Baker, DP1
Furuhashi, N1
Tsujiei, M1
Carlström, K1
Bergqvist, A1
Ljungberg, O1
Rader, MD1
DeVilla, GO1
Mikuta, JJ1
Baudet, JH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Novel Diagnostic Tools for Endometriosis and Their Exploitation for Prognosis and Prevention of Complications[NCT01301885]230 participants (Anticipated)Observational2005-10-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for estrone and Endometrioma

ArticleYear
Estrogen biosynthesis in endometriosis: molecular basis and clinical relevance.
    Journal of molecular endocrinology, 2000, Volume: 25, Issue:1

    Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Dinoprostone; Endometriosis; Enzyme Inhibitors; Estrog

2000
Role of aromatase in endometrial disease.
    The Journal of steroid biochemistry and molecular biology, 2001, Volume: 79, Issue:1-5

    Topics: Aromatase; Aromatase Inhibitors; Dinoprostone; Endometriosis; Enzyme Inhibitors; Estradiol; Estrogen

2001
Estrogen-replacement therapy in patients with previous endometrial carcinoma.
    Comprehensive therapy, 1990, Volume: 16, Issue:1

    Topics: Adenocarcinoma; Endometriosis; Estradiol; Estrogen Replacement Therapy; Estrone; Female; Humans; Neo

1990

Trials

4 trials available for estrone and Endometrioma

ArticleYear
Estrogenic suppression by different administration schedules of goserelin depot for treatment of endometriosis.
    Journal of endocrinological investigation, 1993, Volume: 16, Issue:10

    Topics: Adult; Delayed-Action Preparations; Endometriosis; Estrogen Antagonists; Estrone; Female; Follicular

1993
Endocrine effects of GnRH analogue with low-dose hormone replacement therapy in women with endometriosis.
    Clinical endocrinology, 1995, Volume: 43, Issue:5

    Topics: Adult; Antineoplastic Agents, Hormonal; Endometriosis; Estradiol; Estrogen Replacement Therapy; Estr

1995
Treatment of endometriosis with the antiprogesterone mifepristone (RU486)
    Fertility and sterility, 1996, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Endometriosis; Estrone; Female; Hormone Antagonists; Humans; Luteinizing Hormone;

1996
Efficacy of every-other-day administration of conjugated equine estrogen and medroxyprogesterone acetate on gonadotropin-releasing hormone agonists treatment in women with endometriosis.
    Gynecologic and obstetric investigation, 2001, Volume: 52, Issue:4

    Topics: Adult; Animals; Bone Density; Bone Remodeling; CA-125 Antigen; Endometriosis; Estradiol; Estrogens,

2001

Other Studies

27 other studies available for estrone and Endometrioma

ArticleYear
Association of microbial dynamics with urinary estrogens and estrogen metabolites in patients with endometriosis.
    PloS one, 2021, Volume: 16, Issue:12

    Topics: Adult; Chromatography, Liquid; Dysbiosis; Endometriosis; Estradiol; Estrogens; Female; Humans; Hydro

2021
Markers of Local and Systemic Estrogen Metabolism in Endometriosis.
    Reproductive sciences (Thousand Oaks, Calif.), 2021, Volume: 28, Issue:4

    Topics: Biomarkers; Chromatography, Liquid; Endometriosis; Endometrium; Estrogens; Female; Humans; Hydroxyes

2021
Chemical Synthesis and Biological Evaluation of 3-Substituted Estrone/Estradiol Derivatives as 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors Acting via a Reverse Orientation of the Natural Substrate Estrone.
    Molecules (Basel, Switzerland), 2023, Jan-07, Volume: 28, Issue:2

    Topics: 17-Hydroxysteroid Dehydrogenases; Breast Neoplasms; Cell Line, Tumor; Endometriosis; Enzyme Inhibito

2023
Circulating estradiol and its biologically active metabolites in endometriosis and in relation to pain symptoms.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Endometriosis; Estradiol; Estrogens; Estrone; Female; Humans; Pain; Retrospective Studies

2022
Interleukin-4 and prostaglandin E2 synergistically up-regulate 3β-hydroxysteroid dehydrogenase type 2 in endometrioma stromal cells.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:4

    Topics: Cells, Cultured; Dinoprostone; Drug Synergism; Endometriosis; Estrone; Female; Gene Expression Regul

2013
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.
    Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19

    Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Discovery; Endometriosi

2015
Evaluation of estrogen treatment in an immunodeficient mouse endometriosis model.
    Gynecologic and obstetric investigation, 2009, Volume: 68, Issue:4

    Topics: Adult; Animals; Disease Models, Animal; Endometriosis; Endometrium; Estradiol; Estrone; Female; Fluo

2009
Endometrial and endometriotic concentrations of estrone and estradiol are determined by local metabolism rather than circulating levels.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:11

    Topics: Adult; Endometriosis; Endometrium; Estradiol; Estrone; Female; Humans; Ovarian Diseases; Peritoneal

2012
The effect of estrone and progesterone on the growth of experimental endometriosis in rhesus monkeys.
    American journal of obstetrics and gynecology, 1957, Volume: 74, Issue:4

    Topics: Animals; Endometriosis; Estrogens; Estrone; Female; Humans; Macaca mulatta; Progesterone

1957
THE DETERMINATION OF STEROIDS IN CYST FLUID FROM HUMAN POLYCYSTIC OVARIES.
    The Journal of endocrinology, 1963, Volume: 27

    Topics: Androgens; Chromatography; Cyst Fluid; Cysts; Dehydroepiandrosterone; Endometriosis; Estradiol; Estr

1963
Functional imaging of estrogen receptors with radiolabeled-GAP-EDL in rabbit endometriosis model.
    Academic radiology, 2007, Volume: 14, Issue:9

    Topics: Animals; Disease Models, Animal; Endometriosis; Endometrium; Estrone; Female; Organotechnetium Compo

2007
Danazol: endocrine and endometrial effects.
    International journal of fertility, 1980, Volume: 25, Issue:1

    Topics: Androstenedione; Danazol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Endometriosis; End

1980
Hormonal effects of danazol and medical oophorectomy in endometriosis.
    Obstetrics and gynecology, 1983, Volume: 62, Issue:4

    Topics: Castration; Danazol; Endometriosis; Estradiol; Estrone; Female; Gonadotropin-Releasing Hormone; Huma

1983
"Medical oophorectomy" using a long-acting GNRH agonist--a possible new approach to the treatment of endometriosis.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:5

    Topics: Endometriosis; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Horm

1982
The induction of adenomyosis in mice by intrauterine pituitary isografts.
    Life sciences, 1981, Sep-21, Volume: 29, Issue:12

    Topics: Animals; Castration; Endometriosis; Estrone; Female; Male; Mice; Pituitary Gland, Anterior; Progeste

1981
Low dose intranasal nafarelin for the treatment of endometriosis.
    Acta obstetricia et gynecologica Scandinavica, 1994, Volume: 73, Issue:2

    Topics: Abdominal Pain; Administration, Intranasal; Adult; Bone Density; Dose-Response Relationship, Drug; D

1994
Effects of estrogen, progesterone, and methoxychlor on surgically induced endometriosis in rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1995, Volume: 27, Issue:2

    Topics: Animals; Endometriosis; Estrone; Female; Insecticides; Methoxychlor; Ovariectomy; Progesterone; Rats

1995
Pharmacologic, but not dietary, genistein supports endometriosis in a rat model.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 61, Issue:1

    Topics: Animals; Blotting, Western; Body Weight; Chromatography, High Pressure Liquid; Diet; Disease Models,

2001
[Estrogen substitution and endometrial carcinoma].
    Nederlands tijdschrift voor geneeskunde, 1979, Mar-10, Volume: 123, Issue:10

    Topics: Aged; Endometriosis; Estradiol; Estrogens; Estrogens, Conjugated (USP); Estrone; Female; Humans; Men

1979
Hormonal changes associated with Danazol therapy.
    Obstetrics and gynecology, 1975, Volume: 45, Issue:3

    Topics: Alkynes; Amenorrhea; Cytosol; Endometriosis; Estradiol; Estrone; Female; Follicle Stimulating Hormon

1975
The effects of danazol on gonadotropins and steroid blood levels in normal and anovulatory women.
    American journal of obstetrics and gynecology, 1975, Mar-15, Volume: 121, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Alkynes; Endometriosis; Estradiol; Estrogen Antag

1975
The effects of combining norethindrone with a gonadotropin-releasing hormone agonist in the treatment of symptomatic endometriosis.
    Fertility and sterility, 1990, Volume: 53, Issue:4

    Topics: Adult; Buserelin; Drug Therapy, Combination; Endometriosis; Estradiol; Estrone; Female; Follicle Sti

1990
Treatment of endometriosis with a long-acting gonadotropin-releasing hormone agonist plus medroxyprogesterone acetate.
    Obstetrics and gynecology, 1990, Volume: 75, Issue:4

    Topics: Adult; Drug Therapy, Combination; Endometriosis; Estradiol; Estrone; Female; Flushing; Follicle Stim

1990
[Clinical significance of serum estrone analysis in endocrine tests of the gonadal and placental system].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 48 Suppl

    Topics: Adolescent; Adult; Aging; Endometriosis; Estrone; Female; Humans; Male; Obesity; Polycystic Ovary Sy

1989
Metabolism of estrone sulfate in endometriotic tissue and in uterine endometrium in proliferative and secretory cycle phase.
    Fertility and sterility, 1988, Volume: 49, Issue:2

    Topics: Endometriosis; Endometrium; Estradiol; Estrogens, Conjugated (USP); Estrone; Female; Humans; In Vitr

1988
Plasma estrogens in postmenopausal women.
    American journal of obstetrics and gynecology, 1973, Aug-15, Volume: 116, Issue:8

    Topics: Adult; Age Factors; Aged; Body Weight; Castration; Diabetes Mellitus; Endometrial Hyperplasia; Endom

1973
[The painful syndromes of the cycle].
    La Presse medicale, 1969, May-28, Volume: 77, Issue:26

    Topics: Adolescent; Adult; Cervix Mucus; Diuretics; Dysmenorrhea; Endometriosis; Estrone; Female; Humans; Hy

1969