estrone has been researched along with Down Syndrome in 2 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nankin, HR | 1 |
| Talbott, JB | 1 |
| Oshima, H | 1 |
| Fan, DF | 1 |
| Pan, SF | 1 |
| Troen, P | 1 |
| Stone, D | 1 |
1 review available for estrone and Down Syndrome
| Article | Year |
|---|---|
Chromosomal mosaicism in the human and chromosomal change in vitro.
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosomes; Chromosomes, Human, 13-15; Chromosomes, H | 1966 |
1 other study available for estrone and Down Syndrome
| Article | Year |
|---|---|
Down and Klinefelter syndromes (48, XXY, G+) in a young man. Cytogenetic, endocrine, and testicular steroidogenesis studies.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenedione; Androstenols; Dehydroepiandrosterone; Down Syn | 1974 |