estrone has been researched along with Disease Models, Animal in 38 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of genetically obese rats with oleoyl-estrone in liposomes (Merlin-2) results in sustained loss of body weight-mainly lipid, sparing protein-for up to 28 d, essentially preventing further increase in body weight and accumulation of lipid and protein." | 7.69 | Effect of the slimming agent oleoyl-estrone in liposomes on the body weight of Zucker obese rats. ( Alemany, M; Balada, F; Estruch, J; Fernández-López, JA; Grasa, MM; Remesar, X; Sanchis, D; Virgili, J, 1997) |
| "Adenomatous cells obtained from a pituitary tumor induced in Fisher 344/Lis rats by the subcutaneous implantation of estrone (E1) were found to secrete large amounts of prolactin (PRL)." | 7.67 | Presence of high affinity dopamine receptors in estrone-induced, prolactin-secreting rat pituitary adenomas: a model for human prolactinomas. ( Collu, R; Eljarmak, D; Lis, M; Marchisio, AM, 1985) |
| " Our results suggest a critical role for ER modulation and genistein bioavailability in the maintenance of the implants." | 5.31 | Pharmacologic, but not dietary, genistein supports endometriosis in a rat model. ( Cotroneo, MS; Lamartiniere, CA, 2001) |
| "Treatment of genetically obese rats with oleoyl-estrone in liposomes (Merlin-2) results in sustained loss of body weight-mainly lipid, sparing protein-for up to 28 d, essentially preventing further increase in body weight and accumulation of lipid and protein." | 3.69 | Effect of the slimming agent oleoyl-estrone in liposomes on the body weight of Zucker obese rats. ( Alemany, M; Balada, F; Estruch, J; Fernández-López, JA; Grasa, MM; Remesar, X; Sanchis, D; Virgili, J, 1997) |
| "Adenomatous cells obtained from a pituitary tumor induced in Fisher 344/Lis rats by the subcutaneous implantation of estrone (E1) were found to secrete large amounts of prolactin (PRL)." | 3.67 | Presence of high affinity dopamine receptors in estrone-induced, prolactin-secreting rat pituitary adenomas: a model for human prolactinomas. ( Collu, R; Eljarmak, D; Lis, M; Marchisio, AM, 1985) |
| "Brain edema and diffuse axonal injury (DAI) were assessed by diffusion tensor imaging (DTI), and cerebral glycolysis was measured by (18)F-labeled fluorodeoxyglucose (FDG) positron emission tomography (PET) imaging, at 1 and 7 days after E2-SO4 injection." | 1.42 | Salutary Effects of Estrogen Sulfate for Traumatic Brain Injury. ( Cam-Etoz, B; Chaudry, IH; Hubbard, WJ; Kim, H; Zhai, G; Zinn, KR, 2015) |
| "Endometriosis is known to be an estrogen-dependent disease." | 1.35 | Evaluation of estrogen treatment in an immunodeficient mouse endometriosis model. ( Colette, S; Defrère, S; Donnez, J; Loumaye, E; Lousse, JC; Van Langendonckt, A, 2009) |
| "BHD knockout mice developed enlarged polycystic kidneys and died from renal failure by 3 weeks of age." | 1.35 | Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys. ( Alvord, WG; Baba, M; Bernardo, M; Choyke, P; Furihata, M; Haines, DC; Hong, SB; Igarashi, P; Ileva, L; Leighty, R; Linehan, WM; Patel, V; Schmidt, LS; Southon, E; Tessarollo, L; Warren, MB; Yao, M; Zbar, B, 2008) |
| " Dose-response studies in the same rat model demonstrated that more than 90% inhibition of STS activity in tumors was necessary to induce tumor shrinkage." | 1.34 | A novel steroidal selective steroid sulfatase inhibitor KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells in vitro and in animal models. ( Akinaga, S; Anazawa, H; Ishida, H; Kuwabara, T; Li, PK; Murakata, C; Nakata, T; Sato, N; Shiotsu, Y; Suzuki, M; Takebayashi, M; Tanaka, H; Terasaki, Y, 2007) |
| "Endometriosis is a common women's health problem." | 1.34 | Functional imaging of estrogen receptors with radiolabeled-GAP-EDL in rabbit endometriosis model. ( Borne, A; Kim, EE; Kohanim, S; Kurihara, H; Mawlawi, O; Oh, CS; Takahashi, N; Yang, DJ, 2007) |
| "Oestriol treatment had no effect on dopaminergic markers in MPTP mice whereas oestrone prevented striatal DAT loss and the decrease of VMAT2 mRNA in the substantia nigra." | 1.33 | Oestrogens prevent loss of dopamine transporter (DAT) and vesicular monoamine transporter (VMAT2) in substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice. ( Di Paolo, T; Jourdain, S; Morin, N; Morissette, M, 2005) |
| "Valsartan is a highly selective angiotensin II AT1-receptor antagonist for the treatment of hypertension." | 1.33 | Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans. ( Adachi, Y; Hirouchi, M; Hu, Z; Maeda, K; Sugiyama, Y; Yamashiro, W, 2006) |
| " Our results suggest a critical role for ER modulation and genistein bioavailability in the maintenance of the implants." | 1.31 | Pharmacologic, but not dietary, genistein supports endometriosis in a rat model. ( Cotroneo, MS; Lamartiniere, CA, 2001) |
| "Renal cortical necrosis was induced by the administration of vasopressin to oestrogen-pretreated rats." | 1.27 | Histochemical and ultrastructural study of renal cortical necrosis in rats treated with oestrone + vasopressin, and its prevention with a vasopressin antagonist. ( Karácsony, G; Karcsú, S; Kocsis, J; László, FA, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (28.95) | 18.7374 |
| 1990's | 6 (15.79) | 18.2507 |
| 2000's | 13 (34.21) | 29.6817 |
| 2010's | 7 (18.42) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Karateke, A | 1 |
| Dokuyucu, R | 1 |
| Dogan, H | 1 |
| Ozgur, T | 1 |
| Tas, ZA | 1 |
| Tutuk, O | 1 |
| Agturk, G | 1 |
| Tumer, C | 1 |
| El-Naggar, M | 1 |
| Amr, AEE | 1 |
| Fayed, AA | 1 |
| Elsayed, EA | 1 |
| Al-Omar, MA | 1 |
| Abdalla, MM | 1 |
| Camacho, L | 1 |
| Peña, L | 1 |
| González Gil, A | 1 |
| Cáceres, S | 1 |
| Díez, L | 1 |
| Illera, JC | 1 |
| Hasumi, Y | 1 |
| Baba, M | 2 |
| Hasumi, H | 1 |
| Huang, Y | 1 |
| Lang, M | 1 |
| Reindorf, R | 1 |
| Oh, HB | 1 |
| Sciarretta, S | 1 |
| Nagashima, K | 1 |
| Haines, DC | 2 |
| Schneider, MD | 1 |
| Adelstein, RS | 1 |
| Schmidt, LS | 2 |
| Sadoshima, J | 1 |
| Marston Linehan, W | 1 |
| Yager, JD | 1 |
| Kim, H | 1 |
| Cam-Etoz, B | 1 |
| Zhai, G | 1 |
| Hubbard, WJ | 1 |
| Zinn, KR | 1 |
| Chaudry, IH | 1 |
| Colette, S | 1 |
| Defrère, S | 1 |
| Lousse, JC | 1 |
| Van Langendonckt, A | 1 |
| Loumaye, E | 1 |
| Donnez, J | 1 |
| Liu, R | 1 |
| Yang, SH | 1 |
| Perez, E | 2 |
| Yi, KD | 1 |
| Wu, SS | 1 |
| Eberst, K | 1 |
| Prokai, L | 1 |
| Prokai-Tatrai, K | 1 |
| Cai, ZY | 1 |
| Covey, DF | 1 |
| Day, AL | 1 |
| Simpkins, JW | 2 |
| Ohtsuki, S | 1 |
| Kikkawa, T | 1 |
| Mori, S | 1 |
| Hori, S | 1 |
| Takanaga, H | 1 |
| Otagiri, M | 1 |
| Terasaki, T | 1 |
| Jourdain, S | 1 |
| Morissette, M | 1 |
| Morin, N | 1 |
| Di Paolo, T | 1 |
| Wen, Y | 1 |
| Yang, S | 1 |
| Wang, X | 1 |
| Yamashiro, W | 1 |
| Maeda, K | 1 |
| Hirouchi, M | 1 |
| Adachi, Y | 1 |
| Hu, Z | 1 |
| Sugiyama, Y | 1 |
| Heal, DJ | 1 |
| Ishida, H | 1 |
| Nakata, T | 1 |
| Suzuki, M | 1 |
| Shiotsu, Y | 1 |
| Tanaka, H | 1 |
| Sato, N | 1 |
| Terasaki, Y | 1 |
| Takebayashi, M | 1 |
| Anazawa, H | 1 |
| Murakata, C | 1 |
| Li, PK | 1 |
| Kuwabara, T | 1 |
| Akinaga, S | 1 |
| Takahashi, N | 1 |
| Yang, DJ | 1 |
| Kurihara, H | 1 |
| Borne, A | 1 |
| Kohanim, S | 1 |
| Oh, CS | 1 |
| Mawlawi, O | 1 |
| Kim, EE | 1 |
| Furihata, M | 1 |
| Hong, SB | 1 |
| Tessarollo, L | 1 |
| Southon, E | 1 |
| Patel, V | 1 |
| Igarashi, P | 1 |
| Alvord, WG | 1 |
| Leighty, R | 1 |
| Yao, M | 1 |
| Bernardo, M | 1 |
| Ileva, L | 1 |
| Choyke, P | 1 |
| Warren, MB | 1 |
| Zbar, B | 1 |
| Linehan, WM | 1 |
| Van Thiel, DH | 1 |
| Gavaler, JS | 1 |
| Slone, FL | 1 |
| Cobb, CF | 1 |
| Smith, WI | 1 |
| Bron, KM | 1 |
| Lester, R | 1 |
| Li, S | 1 |
| Martel, C | 1 |
| Dauvois, S | 1 |
| Bélanger, A | 1 |
| Labrie, F | 1 |
| Anderson, E | 2 |
| Lee, GY | 2 |
| Ivasenko, IN | 1 |
| Solov'ev, MM | 1 |
| Mel'tsova, GM | 1 |
| Ivasenko, DA | 1 |
| Almazov, VA | 1 |
| Silva, EG | 1 |
| Tornos, C | 1 |
| Fritsche, HA | 1 |
| el-Naggar, A | 1 |
| Gray, K | 1 |
| Ordonez, NG | 1 |
| Luna, M | 1 |
| Gershenson, D | 1 |
| Balada, F | 1 |
| Sanchis, D | 1 |
| Grasa, MM | 1 |
| Virgili, J | 1 |
| Estruch, J | 1 |
| Fernández-López, JA | 1 |
| Remesar, X | 1 |
| Alemany, M | 1 |
| Lundon, KM | 1 |
| Jayo, MJ | 1 |
| Register, TC | 1 |
| Dumitriu, M | 1 |
| Grynpas, MD | 1 |
| Cotroneo, MS | 1 |
| Lamartiniere, CA | 1 |
| Woo, D | 1 |
| Aziz, N | 1 |
| Walsh, PC | 1 |
| Wilson, JD | 1 |
| Lange, SC | 1 |
| Julien, RM | 1 |
| Novy, MJ | 1 |
| Walsh, SW | 1 |
| Kittinger, GW | 1 |
| Lopez del Pino, V | 1 |
| Bolt, HM | 1 |
| Bogovich, K | 1 |
| Martin, RB | 1 |
| Butcher, RL | 1 |
| Sherwood, LL | 1 |
| Buckendahl, P | 1 |
| Boyd, RD | 1 |
| Farris, D | 1 |
| Sharkey, N | 1 |
| Dannucci, G | 1 |
| Kocsis, J | 1 |
| Karácsony, G | 1 |
| Karcsú, S | 1 |
| László, FA | 1 |
| Eljarmak, D | 1 |
| Marchisio, AM | 1 |
| Lis, M | 1 |
| Collu, R | 1 |
| Heath, H | 1 |
| Shanklin, DR | 1 |
| Wolfson, SL | 1 |
| Hamlett, JD | 1 |
3 reviews available for estrone and Disease Models, Animal
| Article | Year |
|---|---|
Mechanisms of estrogen carcinogenesis: The role of E2/E1-quinone metabolites suggests new approaches to preventive intervention--A review.
Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Carcinogens; Disease Models, Animal; Estradiol; | 2015 |
Role of nonfeminizing estrogens in brain protection from cerebral ischemia: an animal model of Alzheimer's disease neuropathology.
Topics: Alzheimer Disease; Animals; Apoptosis; Brain Ischemia; Cyclin-Dependent Kinases; Disease Models, Ani | 2005 |
Experimentally induced retinopathies in relation to the problem of diabetes.
Topics: Adrenocorticotropic Hormone; Animals; Cortisone; Cyanides; Diabetes Mellitus, Experimental; Diabetic | 1970 |
1 trial available for estrone and Disease Models, Animal
| Article | Year |
|---|---|
Aqueous estrogens in the management of respiratory distress syndrome.
Topics: Animals; Apgar Score; Clinical Trials as Topic; Disease Models, Animal; Drug Synergism; Estrogens; E | 1970 |
34 other studies available for estrone and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Investigation of Therapeutic Effects of Erdosteine on Polycystic Ovary Syndrome in a Rat Model.
Topics: Analysis of Variance; Animals; Blood Glucose; Cholesterol; Disease Models, Animal; Estrone; Expector | 2018 |
Potent Anti-Ovarian Cancer with Inhibitor Activities on both Topoisomerase II and
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chemistry Techniques, Synthetic; Di | 2019 |
Establishment and characterization of a canine xenograft model of inflammatory mammary carcinoma.
Topics: Androstenedione; Animals; Breast; Cyclooxygenase 2; Disease Models, Animal; Dog Diseases; Dogs; Estr | 2013 |
Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Cardiomegaly; Cell Line; Disease Mod | 2014 |
Salutary Effects of Estrogen Sulfate for Traumatic Brain Injury.
Topics: Animals; Brain Edema; Brain Injuries; Diffuse Axonal Injury; Diffusion Tensor Imaging; Disease Model | 2015 |
Evaluation of estrogen treatment in an immunodeficient mouse endometriosis model.
Topics: Adult; Animals; Disease Models, Animal; Endometriosis; Endometrium; Estradiol; Estrone; Female; Fluo | 2009 |
Neuroprotective effects of a novel non-receptor-binding estrogen analogue: in vitro and in vivo analysis.
Topics: Adamantane; Animals; Binding, Competitive; Blood Flow Velocity; Brain; Cell Line; Cell Survival; Cer | 2002 |
Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Capillaries; Disease Models, Animal; Estrone; Ma | 2004 |
Oestrogens prevent loss of dopamine transporter (DAT) and vesicular monoamine transporter (VMAT2) in substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice.
Topics: Animals; Disease Models, Animal; Dopamine; Estradiol; Estriol; Estrogens; Estrone; Injections, Intra | 2005 |
Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans.
Topics: Adenosine Triphosphate; Angiotensin II Type 1 Receptor Blockers; Animals; Bile; Cell Line; Cell Memb | 2006 |
Obesity drug development - CBI's 2nd Annual Summit.
Topics: Adipocytes; Animals; Anti-Obesity Agents; Cannabinoid Receptor Modulators; Disease Models, Animal; D | 2006 |
A novel steroidal selective steroid sulfatase inhibitor KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells in vitro and in animal models.
Topics: Administration, Oral; Animals; Breast Neoplasms; Cell Proliferation; Coumarins; Cricetinae; Disease | 2007 |
Functional imaging of estrogen receptors with radiolabeled-GAP-EDL in rabbit endometriosis model.
Topics: Animals; Disease Models, Animal; Endometriosis; Endometrium; Estrone; Female; Organotechnetium Compo | 2007 |
Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.
Topics: Animals; Antibiotics, Antineoplastic; Blotting, Southern; Cell Proliferation; Disease Models, Animal | 2008 |
Is feminization in alcoholic men due in part to portal hypertension: a rat model.
Topics: Animals; Corticosterone; Disease Models, Animal; Estradiol; Estrone; Ethanol; Feminization; Humans; | 1980 |
Effect of estrone on the growth of 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in the rat: a model of postmenopausal breast cancer.
Topics: 17-Hydroxysteroid Dehydrogenases; 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; | 1994 |
The polycystic ovarian (PCO) condition: apoptosis and epithelialization of the ovarian antral follicles are aspects of cystogenesis in the dehydroepiandrosterone (DHEA)-treated rat model.
Topics: Androgens; Animals; Apoptosis; Cytoskeleton; Dehydroepiandrosterone; Disease Models, Animal; Epithel | 1997 |
[Effect of combined treatment with hydroxyapatite and estrone on tooth alveolus healing in experiment].
Topics: Administration, Topical; Animals; Autoradiography; Biocompatible Materials; Bone Regeneration; Cell | 1997 |
The induction of benign epithelial neoplasms of the ovaries of guinea pigs by testosterone stimulation: a potential animal model.
Topics: Animals; Chorionic Gonadotropin; Cystadenoma; Disease Models, Animal; Epithelium; Estrone; Female; G | 1997 |
Effect of the slimming agent oleoyl-estrone in liposomes on the body weight of Zucker obese rats.
Topics: Animals; Anti-Obesity Agents; Blood Glucose; Body Composition; Body Weight; Cholesterol; Cohort Stud | 1997 |
The effect of androstenedione/estrone supplementation on cortical and cancellous bone in the young intact female monkey: a model for the effects of polycystic ovarian disease on the skeleton?
Topics: Absorptiometry, Photon; Acid Phosphatase; Alkaline Phosphatase; Androstenedione; Animals; Biomarkers | 2000 |
Pharmacologic, but not dietary, genistein supports endometriosis in a rat model.
Topics: Animals; Blotting, Western; Body Weight; Chromatography, High Pressure Liquid; Diet; Disease Models, | 2001 |
Immature ovaries and polycystic kidneys in the congenital polycystic kidney mouse may be due to abnormal sex steroid metabolism.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Chorionic Gonadotropin; Dihydrotestosterone; Disease Mode | 2001 |
The induction of prostatic hypertrophy in the dog with androstanediol.
Topics: Androstane-3,17-diol; Androstanes; Animals; Castration; Dihydrotestosterone; Disease Models, Animal; | 1976 |
Re-evaluation of estrogen-induced cortical and thalamic paroxysmal EEG activity in the cat.
Topics: Animals; Cats; Cerebral Cortex; Decerebrate State; Disease Models, Animal; Dose-Response Relationshi | 1978 |
Experimental fetal anencephaly in the rhesus monkey: effect on gestational length and fetal and maternal plasma steroids.
Topics: Anencephaly; Animals; Cortisone; Disease Models, Animal; Estradiol; Estrone; Female; Fetal Blood; Fe | 1977 |
[The thioacetamide-poisoned rat as an animal experimental model for endocrinological studies of estrogen metabolism in chronic liver injury)].
Topics: Acetamides; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Chemical and Drug Induced Liver | 1975 |
Follicle-stimulating hormone plays a role in the induction of ovarian follicular cysts in hypophysectomized rats.
Topics: Androstenedione; Animals; Chorionic Gonadotropin; Cyclic AMP; Dihydrotestosterone; Disease Models, A | 1992 |
Effects of ovariectomy in beagle dogs.
Topics: Animals; Bone and Bones; Calcium-Binding Proteins; Disease Models, Animal; Dogs; Estradiol; Estrogen | 1987 |
Histochemical and ultrastructural study of renal cortical necrosis in rats treated with oestrone + vasopressin, and its prevention with a vasopressin antagonist.
Topics: Animals; Arginine Vasopressin; Disease Models, Animal; Estrone; Histocytochemistry; Kidney; Kidney C | 1987 |
Presence of high affinity dopamine receptors in estrone-induced, prolactin-secreting rat pituitary adenomas: a model for human prolactinomas.
Topics: Adenoma; Animals; Bromocriptine; Disease Models, Animal; Dopamine; Estrone; Female; Guanosine Tripho | 1985 |
Clinical and experimental observations on ovarian endocrine activity in relation to neoplasia.
Topics: Animals; Dermoid Cyst; Disease Models, Animal; Estrogens; Estrone; Female; Mice; Neoplasm Transplant | 1971 |