estrone has been researched along with Diabetes Mellitus, Adult-Onset in 14 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined the relation of total and free testosterone, sex hormone binding globulin, estrone, estradiol, and DHEA-SO4 to the 5-year IHD mortality in the older-onset diabetic subjects in the Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR) in a matched diabetic subject-control design (two control subjects for every diabetic subject)." | 3.69 | Sex hormones and DHEA-SO4 in relation to ischemic heart disease mortality in diabetic subjects. The Wisconsin Epidemiologic Study of Diabetic Retinopathy. ( Haffner, SM; Klein, BE; Klein, R; Moss, SE, 1996) |
| "Information about the chemical constituents of SJHK were collected, and druggable compounds were screened based on oral bioavailability and drug-likeness." | 1.72 | Network pharmacology and molecular docking approaches to elucidate the potential compounds and targets of Saeng-Ji-Hwang-Ko for treatment of type 2 diabetes mellitus. ( Ahn, D; Chung, SJ; Jeong, S; Kim, H; Kim, HH; Kim, Y; Ko, M, 2022) |
| "Type 2 diabetes mellitus was defined as fasting glucose >125 mg/dL, medication use, or both." | 1.39 | Circulating estrone levels are associated prospectively with diabetes risk in men of the Framingham Heart Study. ( Bhasin, S; Coviello, AD; D'Agostino, R; Davda, M; Jasuja, GK; Kushnir, MM; Meikle, W; Rockwood, AL; Rose, AJ; Travison, TG; Vasan, RS; Zhang, A, 2013) |
| "Postmenopausal Hispanic women with type 2 diabetes had both hyperandrogenemia and hyperestrogenemia, and testosterone or FT correlated positively with risk factors for CHD." | 1.31 | Association of hyperandrogenemia and hyperestrogenemia with type 2 diabetes in Hispanic postmenopausal women. ( Boden-Albala, B; Dahodwala, N; Jing, TY; Lin, IF; Phillips, GB; Sacco, RL; Tuck, CH, 2000) |
| "RESULTS--Women with NIDDM had somewhat higher plasma insulin concentrations, lower SHBG, and higher free testosterone values than did control subjects with similar body mass index (BMI)." | 1.29 | Testosterone concentrations in women and men with NIDDM. ( Andersson, B; Björntorp, P; Lissner, L; Mårin, P; Vermeulen, A, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Ko, M | 1 |
| Kim, Y | 1 |
| Kim, HH | 1 |
| Jeong, S | 1 |
| Ahn, D | 1 |
| Chung, SJ | 1 |
| Kim, H | 1 |
| Zhang, J | 1 |
| You, G | 1 |
| Jasuja, GK | 1 |
| Travison, TG | 1 |
| Davda, M | 1 |
| Rose, AJ | 1 |
| Zhang, A | 1 |
| Kushnir, MM | 1 |
| Rockwood, AL | 1 |
| Meikle, W | 1 |
| Coviello, AD | 1 |
| D'Agostino, R | 1 |
| Vasan, RS | 1 |
| Bhasin, S | 1 |
| Ontawong, A | 1 |
| Saowakon, N | 1 |
| Vivithanaporn, P | 1 |
| Pongchaidecha, A | 1 |
| Lailerd, N | 1 |
| Amornlerdpison, D | 1 |
| Lungkaphin, A | 1 |
| Srimaroeng, C | 1 |
| Villarroel, C | 1 |
| Salinas, A | 1 |
| López, P | 1 |
| Kohen, P | 1 |
| Rencoret, G | 1 |
| Devoto, L | 1 |
| Codner, E | 1 |
| Posadas, MD | 1 |
| Olguín, MC | 1 |
| Zingale, MI | 1 |
| Revelant, G | 1 |
| Labourdette, V | 1 |
| Gayol, Mdel C | 1 |
| Calderari, S | 1 |
| Jacobson, PB | 1 |
| von Geldern, TW | 1 |
| Ohman, L | 1 |
| Osterland, M | 1 |
| Wang, J | 1 |
| Zinker, B | 1 |
| Wilcox, D | 1 |
| Nguyen, PT | 1 |
| Mika, A | 1 |
| Fung, S | 1 |
| Fey, T | 1 |
| Goos-Nilsson, A | 1 |
| Grynfarb, M | 1 |
| Barkhem, T | 1 |
| Marsh, K | 1 |
| Beno, DW | 1 |
| Nga-Nguyen, B | 1 |
| Kym, PR | 1 |
| Link, JT | 1 |
| Tu, N | 1 |
| Edgerton, DS | 1 |
| Cherrington, A | 1 |
| Efendic, S | 1 |
| Lane, BC | 1 |
| Opgenorth, TJ | 1 |
| Andersson, B | 1 |
| Mårin, P | 1 |
| Lissner, L | 1 |
| Vermeulen, A | 1 |
| Björntorp, P | 1 |
| Haffner, SM | 1 |
| Moss, SE | 1 |
| Klein, BE | 1 |
| Klein, R | 1 |
| Phillips, GB | 1 |
| Tuck, CH | 1 |
| Jing, TY | 1 |
| Boden-Albala, B | 1 |
| Lin, IF | 1 |
| Dahodwala, N | 1 |
| Sacco, RL | 1 |
| Chua, BH | 1 |
| Chua, CC | 1 |
| Zhao, ZY | 1 |
| Krebs, CJ | 1 |
| Kuang, AK | 1 |
| Kuo, TH | 1 |
| Giacomelli, F | 1 |
| Wiener, J | 1 |
| Johnston, CC | 1 |
| Hui, SL | 1 |
| Longcope, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role of Gonadotropin Pulsations in the Reversal of Hypogonadotropic Hypogonadism[NCT00392756] | Phase 1 | 624 participants (Actual) | Interventional | 1989-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 other studies available for estrone and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Network pharmacology and molecular docking approaches to elucidate the potential compounds and targets of Saeng-Ji-Hwang-Ko for treatment of type 2 diabetes mellitus.
Topics: Cyclooxygenase 2; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Estrogens; Estrone; Humans; Insu | 2022 |
Peptide Hormone Insulin Regulates Function, Expression, and SUMOylation of Organic Anion Transporter 3.
Topics: Animals; Chlorocebus aethiops; COS Cells; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, T | 2021 |
Circulating estrone levels are associated prospectively with diabetes risk in men of the Framingham Heart Study.
Topics: Aged; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Estradiol; Estrone; Female; Humans; Male; | 2013 |
Antioxidant and renoprotective effects of Spirogyra neglecta (Hassall) Kützing extract in experimental type 2 diabetic rats.
Topics: Animals; Antioxidants; Biological Transport; Diabetes Mellitus, Experimental; Diabetes Mellitus, Typ | 2013 |
Pregestational type 2 diabetes and gestational diabetes exhibit different sexual steroid profiles during pregnancy.
Topics: Adult; Androstenedione; Chile; Dehydroepiandrosterone Sulfate; Diabetes Mellitus, Type 2; Diabetes, | 2017 |
Oleoyl-estrone metabolic effects in relation with caloric restriction in inbred Beta rats with spontaneous obesity and type 2 diabetes.
Topics: Animals; Anti-Obesity Agents; Body Weight; Caloric Restriction; Cholesterol; Diabetes Mellitus, Type | 2004 |
Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes.
Topics: 3T3 Cells; Adipocytes; Animals; Biotransformation; Blood Glucose; Cell Differentiation; Cholic Acids | 2005 |
Testosterone concentrations in women and men with NIDDM.
Topics: Androgens; Blood Pressure; Body Mass Index; Body Weight; Diabetes Mellitus, Type 2; Estradiol; Estro | 1994 |
Sex hormones and DHEA-SO4 in relation to ischemic heart disease mortality in diabetic subjects. The Wisconsin Epidemiologic Study of Diabetic Retinopathy.
Topics: Adult; Age of Onset; Aged; Biomarkers; C-Peptide; Cross-Sectional Studies; Dehydroepiandrosterone Su | 1996 |
Association of hyperandrogenemia and hyperestrogenemia with type 2 diabetes in Hispanic postmenopausal women.
Topics: Aged; Androgens; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, | 2000 |
Estrone modulates the EGF receptor in the liver of db/db mouse.
Topics: Animals; Chloramphenicol O-Acetyltransferase; Diabetes Mellitus, Type 2; Epidermal Growth Factor; Er | 1991 |
[Changes in plasma sex hormone in postmenopausal type II diabetics and therapeutic effect of diagnosis and treatment with traditional Chinese medicine].
Topics: Aged; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Estradiol; Estrone; Female; Gonadal Steroid | 1988 |
Mitochondrial protein phosphorylation and cardiomyopathy in genetically diabetic mice: the effect of estrone treatment.
Topics: Animals; Cardiomyopathies; Coenzyme A Ligases; Diabetes Mellitus, Type 2; Estrone; Female; In Vitro | 1986 |
Bone mass and sex steroid concentrations in postmenopausal Caucasian diabetics.
Topics: Aged; Bone and Bones; Diabetes Mellitus; Diabetes Mellitus, Type 2; Estrone; Female; Gonadal Steroid | 1985 |