Page last updated: 2024-11-07

estrone and Diabetes Mellitus, Adult-Onset

estrone has been researched along with Diabetes Mellitus, Adult-Onset in 14 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Research Excerpts

ExcerptRelevanceReference
"We examined the relation of total and free testosterone, sex hormone binding globulin, estrone, estradiol, and DHEA-SO4 to the 5-year IHD mortality in the older-onset diabetic subjects in the Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR) in a matched diabetic subject-control design (two control subjects for every diabetic subject)."3.69Sex hormones and DHEA-SO4 in relation to ischemic heart disease mortality in diabetic subjects. The Wisconsin Epidemiologic Study of Diabetic Retinopathy. ( Haffner, SM; Klein, BE; Klein, R; Moss, SE, 1996)
"Information about the chemical constituents of SJHK were collected, and druggable compounds were screened based on oral bioavailability and drug-likeness."1.72Network pharmacology and molecular docking approaches to elucidate the potential compounds and targets of Saeng-Ji-Hwang-Ko for treatment of type 2 diabetes mellitus. ( Ahn, D; Chung, SJ; Jeong, S; Kim, H; Kim, HH; Kim, Y; Ko, M, 2022)
"Type 2 diabetes mellitus was defined as fasting glucose >125 mg/dL, medication use, or both."1.39Circulating estrone levels are associated prospectively with diabetes risk in men of the Framingham Heart Study. ( Bhasin, S; Coviello, AD; D'Agostino, R; Davda, M; Jasuja, GK; Kushnir, MM; Meikle, W; Rockwood, AL; Rose, AJ; Travison, TG; Vasan, RS; Zhang, A, 2013)
"Postmenopausal Hispanic women with type 2 diabetes had both hyperandrogenemia and hyperestrogenemia, and testosterone or FT correlated positively with risk factors for CHD."1.31Association of hyperandrogenemia and hyperestrogenemia with type 2 diabetes in Hispanic postmenopausal women. ( Boden-Albala, B; Dahodwala, N; Jing, TY; Lin, IF; Phillips, GB; Sacco, RL; Tuck, CH, 2000)
"RESULTS--Women with NIDDM had somewhat higher plasma insulin concentrations, lower SHBG, and higher free testosterone values than did control subjects with similar body mass index (BMI)."1.29Testosterone concentrations in women and men with NIDDM. ( Andersson, B; Björntorp, P; Lissner, L; Mårin, P; Vermeulen, A, 1994)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's3 (21.43)18.2507
2000's3 (21.43)29.6817
2010's3 (21.43)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Ko, M1
Kim, Y1
Kim, HH1
Jeong, S1
Ahn, D1
Chung, SJ1
Kim, H1
Zhang, J1
You, G1
Jasuja, GK1
Travison, TG1
Davda, M1
Rose, AJ1
Zhang, A1
Kushnir, MM1
Rockwood, AL1
Meikle, W1
Coviello, AD1
D'Agostino, R1
Vasan, RS1
Bhasin, S1
Ontawong, A1
Saowakon, N1
Vivithanaporn, P1
Pongchaidecha, A1
Lailerd, N1
Amornlerdpison, D1
Lungkaphin, A1
Srimaroeng, C1
Villarroel, C1
Salinas, A1
López, P1
Kohen, P1
Rencoret, G1
Devoto, L1
Codner, E1
Posadas, MD1
Olguín, MC1
Zingale, MI1
Revelant, G1
Labourdette, V1
Gayol, Mdel C1
Calderari, S1
Jacobson, PB1
von Geldern, TW1
Ohman, L1
Osterland, M1
Wang, J1
Zinker, B1
Wilcox, D1
Nguyen, PT1
Mika, A1
Fung, S1
Fey, T1
Goos-Nilsson, A1
Grynfarb, M1
Barkhem, T1
Marsh, K1
Beno, DW1
Nga-Nguyen, B1
Kym, PR1
Link, JT1
Tu, N1
Edgerton, DS1
Cherrington, A1
Efendic, S1
Lane, BC1
Opgenorth, TJ1
Andersson, B1
Mårin, P1
Lissner, L1
Vermeulen, A1
Björntorp, P1
Haffner, SM1
Moss, SE1
Klein, BE1
Klein, R1
Phillips, GB1
Tuck, CH1
Jing, TY1
Boden-Albala, B1
Lin, IF1
Dahodwala, N1
Sacco, RL1
Chua, BH1
Chua, CC1
Zhao, ZY1
Krebs, CJ1
Kuang, AK1
Kuo, TH1
Giacomelli, F1
Wiener, J1
Johnston, CC1
Hui, SL1
Longcope, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Role of Gonadotropin Pulsations in the Reversal of Hypogonadotropic Hypogonadism[NCT00392756]Phase 1624 participants (Actual)Interventional1989-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

14 other studies available for estrone and Diabetes Mellitus, Adult-Onset

ArticleYear
Network pharmacology and molecular docking approaches to elucidate the potential compounds and targets of Saeng-Ji-Hwang-Ko for treatment of type 2 diabetes mellitus.
    Computers in biology and medicine, 2022, Volume: 149

    Topics: Cyclooxygenase 2; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Estrogens; Estrone; Humans; Insu

2022
Peptide Hormone Insulin Regulates Function, Expression, and SUMOylation of Organic Anion Transporter 3.
    The AAPS journal, 2021, 03-11, Volume: 23, Issue:2

    Topics: Animals; Chlorocebus aethiops; COS Cells; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, T

2021
Circulating estrone levels are associated prospectively with diabetes risk in men of the Framingham Heart Study.
    Diabetes care, 2013, Volume: 36, Issue:9

    Topics: Aged; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Estradiol; Estrone; Female; Humans; Male;

2013
Antioxidant and renoprotective effects of Spirogyra neglecta (Hassall) Kützing extract in experimental type 2 diabetic rats.
    BioMed research international, 2013, Volume: 2013

    Topics: Animals; Antioxidants; Biological Transport; Diabetes Mellitus, Experimental; Diabetes Mellitus, Typ

2013
Pregestational type 2 diabetes and gestational diabetes exhibit different sexual steroid profiles during pregnancy.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2017, Volume: 33, Issue:3

    Topics: Adult; Androstenedione; Chile; Dehydroepiandrosterone Sulfate; Diabetes Mellitus, Type 2; Diabetes,

2017
Oleoyl-estrone metabolic effects in relation with caloric restriction in inbred Beta rats with spontaneous obesity and type 2 diabetes.
    Medicina, 2004, Volume: 64, Issue:4

    Topics: Animals; Anti-Obesity Agents; Body Weight; Caloric Restriction; Cholesterol; Diabetes Mellitus, Type

2004
Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:1

    Topics: 3T3 Cells; Adipocytes; Animals; Biotransformation; Blood Glucose; Cell Differentiation; Cholic Acids

2005
Testosterone concentrations in women and men with NIDDM.
    Diabetes care, 1994, Volume: 17, Issue:5

    Topics: Androgens; Blood Pressure; Body Mass Index; Body Weight; Diabetes Mellitus, Type 2; Estradiol; Estro

1994
Sex hormones and DHEA-SO4 in relation to ischemic heart disease mortality in diabetic subjects. The Wisconsin Epidemiologic Study of Diabetic Retinopathy.
    Diabetes care, 1996, Volume: 19, Issue:10

    Topics: Adult; Age of Onset; Aged; Biomarkers; C-Peptide; Cross-Sectional Studies; Dehydroepiandrosterone Su

1996
Association of hyperandrogenemia and hyperestrogenemia with type 2 diabetes in Hispanic postmenopausal women.
    Diabetes care, 2000, Volume: 23, Issue:1

    Topics: Aged; Androgens; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus,

2000
Estrone modulates the EGF receptor in the liver of db/db mouse.
    Journal of receptor research, 1991, Volume: 11, Issue:6

    Topics: Animals; Chloramphenicol O-Acetyltransferase; Diabetes Mellitus, Type 2; Epidermal Growth Factor; Er

1991
[Changes in plasma sex hormone in postmenopausal type II diabetics and therapeutic effect of diagnosis and treatment with traditional Chinese medicine].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1988, Volume: 8, Issue:5

    Topics: Aged; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Estradiol; Estrone; Female; Gonadal Steroid

1988
Mitochondrial protein phosphorylation and cardiomyopathy in genetically diabetic mice: the effect of estrone treatment.
    Biochemical and biophysical research communications, 1986, Aug-29, Volume: 139, Issue:1

    Topics: Animals; Cardiomyopathies; Coenzyme A Ligases; Diabetes Mellitus, Type 2; Estrone; Female; In Vitro

1986
Bone mass and sex steroid concentrations in postmenopausal Caucasian diabetics.
    Metabolism: clinical and experimental, 1985, Volume: 34, Issue:6

    Topics: Aged; Bone and Bones; Diabetes Mellitus; Diabetes Mellitus, Type 2; Estrone; Female; Gonadal Steroid

1985