Page last updated: 2024-11-07

estrone and Cognition Disorders

estrone has been researched along with Cognition Disorders in 8 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"To investigate whether an association exists between estradiol and estrone levels and measures of cognitive functioning in women with Alzheimer disease (AD) treated with conjugated equine estrogen (Premarin; Wyeth-Ayerst, Philadelphia, Pa)."5.10Estrogen levels do not correlate with improvement in cognition. ( Grundman, M; Mulnard, R; Sano, M; Schneider, L; Thal, LJ; Thomas, RG, 2003)
"Androstenedione, the main circulating ovarian hormone present after menopause, has been shown to positively correlate with poor spatial memory in an ovary-intact rodent model of follicular depletion, and to impair spatial memory when administered exogenously to surgically menopausal ovariectomized rats."3.81Pharmacological blockade of the aromatase enzyme, but not the androgen receptor, reverses androstenedione-induced cognitive impairments in young surgically menopausal rats. ( Acosta, JI; Alderete, TJ; Bimonte-Nelson, HA; Camp, BW; Demers, LM; Koebele, SV; Mennenga, SE; Mousa, AA; Tsang, CW, 2015)
"To describe changes in levels of cognitive symptoms (forgetting and difficulty concentrating) during the menopausal transition (MT) stages and early postmenopause, including effects of age, MT-related factors(MT stages, estrone, follicle stimulating hormone (FSH), testosterone), symptoms (hot flush, sleep, mood), health-related factors (alcohol use, smoking, exercise, perceived health), stress-related factors (perceived stress, history of sexual abuse, cortisol, catecholamines) and social factors (partner and parenting status, education, employment)."3.77Cognitive symptoms during the menopausal transition and early postmenopause. ( Mitchell, ES; Woods, NF, 2011)
"Dementia was diagnosed at baseline by clinical assessment and review by a specialist panel."1.42Longitudinal Relationships between Reproductive Hormones and Cognitive Decline in Older Men: The Concord Health and Ageing in Men Project. ( Blyth, FM; Cumming, RG; Handelsman, DJ; Hsu, B; Le Couteur, DG; Naganathan, V; Seibel, MJ; Waite, LM, 2015)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Woods, NF2
Cray, L1
Mitchell, ES2
Herting, JR1
Mennenga, SE1
Koebele, SV1
Mousa, AA1
Alderete, TJ1
Tsang, CW1
Acosta, JI1
Camp, BW1
Demers, LM1
Bimonte-Nelson, HA1
Hsu, B1
Cumming, RG1
Waite, LM1
Blyth, FM1
Naganathan, V1
Le Couteur, DG1
Seibel, MJ1
Handelsman, DJ1
Johansson, P1
Johansson, JO1
Labrie, F1
Mattsson, N1
Hansson, O1
Blennow, K1
Zetterberg, H1
Wallin, A1
Ohlsson, C1
Svensson, J1
Thal, LJ1
Thomas, RG1
Mulnard, R1
Sano, M1
Grundman, M1
Schneider, L1
Mitchell, JL1
Cruickshanks, KJ1
Klein, BE1
Palta, M1
Nondahl, DM1
Lebrun, CE1
van der Schouw, YT1
de Jong, FH1
Pols, HA1
Grobbee, DE1
Lamberts, SW1

Trials

1 trial available for estrone and Cognition Disorders

ArticleYear
Estrogen levels do not correlate with improvement in cognition.
    Archives of neurology, 2003, Volume: 60, Issue:2

    Topics: Aged; Alzheimer Disease; Cognition Disorders; Estradiol; Estrogens, Conjugated (USP); Estrone; Femal

2003

Other Studies

7 other studies available for estrone and Cognition Disorders

ArticleYear
Endocrine biomarkers and symptom clusters during the menopausal transition and early postmenopause: observations from the Seattle Midlife Women's Health Study.
    Menopause (New York, N.Y.), 2014, Volume: 21, Issue:6

    Topics: Adult; Affective Symptoms; Autonomic Nervous System; Cognition Disorders; Estrone; Female; Follicle

2014
Pharmacological blockade of the aromatase enzyme, but not the androgen receptor, reverses androstenedione-induced cognitive impairments in young surgically menopausal rats.
    Steroids, 2015, Volume: 99, Issue:Pt A

    Topics: Anastrozole; Androgen Antagonists; Androstenedione; Animals; Aromatase Inhibitors; Brain; Cognition

2015
Longitudinal Relationships between Reproductive Hormones and Cognitive Decline in Older Men: The Concord Health and Ageing in Men Project.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognition Disorders; Cognitive Dysfunction; Dementia; Dih

2015
Mild dementia is associated with increased adrenal secretion of cortisol and precursor sex steroids in women.
    Clinical endocrinology, 2011, Volume: 75, Issue:3

    Topics: Adrenal Glands; Aged; Aged, 80 and over; Androsterone; Chromatography, Liquid; Cognition Disorders;

2011
Cognitive symptoms during the menopausal transition and early postmenopause.
    Climacteric : the journal of the International Menopause Society, 2011, Volume: 14, Issue:2

    Topics: Adult; Attention; Cognition Disorders; Estrone; Female; Health Status; Humans; Hydrocortisone; Longi

2011
Postmenopausal hormone therapy and its association with cognitive impairment.
    Archives of internal medicine, 2003, Nov-10, Volume: 163, Issue:20

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cognition; Cognition Disorders; Cohort Studies; Estroge

2003
Endogenous oestrogens are related to cognition in healthy elderly women.
    Clinical endocrinology, 2005, Volume: 63, Issue:1

    Topics: Adipose Tissue; Aged; Aging; Body Mass Index; Cognition; Cognition Disorders; Educational Status; Es

2005