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estrone and Choriocarcinoma

estrone has been researched along with Choriocarcinoma in 18 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

Research Excerpts

ExcerptRelevanceReference
"The estradiol (E2) to estriol (E3) ratio during human pregnancy depends on fetal liver hydroxylation of fetal adrenal dehydroepiandrosterone sulfate (DHEAS) and conversion by the trophoblast of DHEAS and 16 alpha-hydroxy-DHEAS (16 OH-DHEAS) to estrone (E1), estradiol (E2), and estriol (E3), respectively."7.67Competitive studies with dehydroepiandrosterone sulfate and 16 alpha-hydroxydehydroepiandrosterone sulfate in cultured human choriocarcinoma JEG-3 cells: effect on estrone, 17 beta-estradiol, and estriol secretion. ( Benveniste, R; Ilekis, J; Scommegna, A; Zbella, EA, 1986)
" A co-culture of H295R human adrenocortical carcinoma cells with fetal characteristics and BeWo human choriocarcinoma cells which display characteristics of the villous cytotrophoblast was exposed for 24h to various concentrations of three neonicotinoids: thiacloprid, thiamethoxam and imidacloprid."3.85The use of a unique co-culture model of fetoplacental steroidogenesis as a screening tool for endocrine disruptors: The effects of neonicotinoids on aromatase activity and hormone production. ( Caron-Beaudoin, E; Hudon-Thibeault, AA; Sanderson, JT; Vaillancourt, C; Viau, R, 2017)
"The estradiol (E2) to estriol (E3) ratio during human pregnancy depends on fetal liver hydroxylation of fetal adrenal dehydroepiandrosterone sulfate (DHEAS) and conversion by the trophoblast of DHEAS and 16 alpha-hydroxy-DHEAS (16 OH-DHEAS) to estrone (E1), estradiol (E2), and estriol (E3), respectively."3.67Competitive studies with dehydroepiandrosterone sulfate and 16 alpha-hydroxydehydroepiandrosterone sulfate in cultured human choriocarcinoma JEG-3 cells: effect on estrone, 17 beta-estradiol, and estriol secretion. ( Benveniste, R; Ilekis, J; Scommegna, A; Zbella, EA, 1986)
"The oxygen dependence of oestrogen (oestrone and 17 beta-oestradiol) formation from androstenedione and testosterone was studied in term human placental microsomes and in cultured human choriocarcinoma cells (BeWo line)."3.67Oxygen dependence of oestrogen production by human placental microsomes and cultured choriocarcinoma cells. ( Aw, TY; Jones, DP; O'Shannessy, DJ; Priest, JH; Priest, RE, 1985)
"Prolactin (PRL), human placental lactogen (hPL), the beta-subunit of human chorionic gonadotropin (betahCG), testosterone (T), estrone (E1), and estradiol (E2) were measured in blood samples from 45 patients with testicular tumors, 27 of whom had gynecomastia at some stage of their disease."3.66Endocrine studies in testicular tumor patients with and without gynecomastia: a report of 45 cases. ( Holoye, PY; Samaan, NA; Schultz, PN; Stepanas, AV, 1978)
" This implies that alterations in placental steroidogenesis and, subsequently, in the functionality or bioavailability of placental aromatase may be mechanistically involved in the pathophysiology of PE."1.42Placental Aromatase Is Deficient in Placental Ischemia and Preeclampsia. ( Dobierzewska, A; España-Perrot, PP; Figueroa-Diesel, H; González, MI; Guzmán-Rojas, AM; Illanes, SE; Irarrazabal, CE; Monteiro, LJ; Palominos-Rivera, M; Perez-Sepulveda, A; Varas-Godoy, M; Venegas-Araneda, P, 2015)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199015 (83.33)18.7374
1990's1 (5.56)18.2507
2000's0 (0.00)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caron-Beaudoin, E1
Viau, R1
Hudon-Thibeault, AA1
Vaillancourt, C1
Sanderson, JT1
Perez-Sepulveda, A1
Monteiro, LJ1
Dobierzewska, A1
España-Perrot, PP1
Venegas-Araneda, P1
Guzmán-Rojas, AM1
González, MI1
Palominos-Rivera, M1
Irarrazabal, CE1
Figueroa-Diesel, H1
Varas-Godoy, M1
Illanes, SE1
Barbieri, RL1
Gao, X1
Maeyama, M1
Ifuku, M1
Nakahara, K1
Miyamoto, T1
Stepanas, AV1
Samaan, NA1
Schultz, PN1
Holoye, PY1
Zbella, EA1
Ilekis, J1
Scommegna, A1
Benveniste, R1
Templ, H1
Kuzmits, R1
Kratzik, C1
Aw, TY1
Jones, DP1
O'Shannessy, DJ1
Priest, JH1
Priest, RE1
Kirschner, MA3
Wider, JA1
Ross, GT1
Cohen, FB1
Jespersen, D1
Pattillo, RA1
Hussa, RO1
Huang, WY1
Delfs, E1
Mattingly, RF1
Kelly, WG1
Rizkallah, TH1
Breuer, J1
Patt, V1
Breuer, H1
Lindenmeyer, D1
Tomanek, M1
Körner, F1
Kohler, PO1
Bridson, WE1
Hammond, JM1
Weintraub, B1
Van Thiel, DH1
Gurpide, E1
Stolee, A1
Tseng, L1
Brinck-Johnsen, T1
Solc, J1
Galton, VA1

Other Studies

18 other studies available for estrone and Choriocarcinoma

ArticleYear
The use of a unique co-culture model of fetoplacental steroidogenesis as a screening tool for endocrine disruptors: The effects of neonicotinoids on aromatase activity and hormone production.
    Toxicology and applied pharmacology, 2017, 10-01, Volume: 332

    Topics: Adrenocortical Carcinoma; Aromatase; Cell Line, Tumor; Choriocarcinoma; Coculture Techniques; Cytoch

2017
Placental Aromatase Is Deficient in Placental Ischemia and Preeclampsia.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Adult; Androgens; Androstenedione; Animals; Aromatase; Case-Control Studies; Cell Line, Tumor; Chori

2015
17 beta-Hydroxysteroid dehydrogenase: enzymatic activity and mRNA species in choriocarcinoma cells.
    Gynecologic and obstetric investigation, 1994, Volume: 37, Issue:3

    Topics: 17-Hydroxysteroid Dehydrogenases; Blotting, Northern; Blotting, Western; Choriocarcinoma; Codon; Est

1994
Steroidogenesis in cerebral metastatic chorionepithelioma tissue in vitro.
    The Journal of endocrinology, 1975, Volume: 65, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Brain Neoplasms; Choriocarcinoma; Dehydroepiandroster

1975
[Fluctuations of plasma progesterone, 17alpha-OH-progesterone and estrogens in trophoblastic diseases (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1977, Mar-20, Volume: 53, Issue:3

    Topics: Adult; Choriocarcinoma; Chorionic Gonadotropin; Estradiol; Estrogens; Estrone; Female; Humans; Hydat

1977
Endocrine studies in testicular tumor patients with and without gynecomastia: a report of 45 cases.
    Cancer, 1978, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Choriocarcinoma; Chorionic Gonadotropin; Dysgerminoma; Estradiol; Estrone;

1978
Competitive studies with dehydroepiandrosterone sulfate and 16 alpha-hydroxydehydroepiandrosterone sulfate in cultured human choriocarcinoma JEG-3 cells: effect on estrone, 17 beta-estradiol, and estriol secretion.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 63, Issue:3

    Topics: Cells, Cultured; Choriocarcinoma; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol;

1986
Microsomal aromatase in testicular tumour tissue: increased activity in choriocarcinoma compared to embryonal carcinoma.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1988, Volume: 20, Issue:8

    Topics: Androstenedione; Aromatase; Choriocarcinoma; Dysgerminoma; Estradiol; Estrone; Humans; Male; Microso

1988
Oxygen dependence of oestrogen production by human placental microsomes and cultured choriocarcinoma cells.
    Journal of steroid biochemistry, 1985, Volume: 22, Issue:6

    Topics: Androstenedione; Aromatase; Cell Line; Choriocarcinoma; Estradiol; Estrogens; Estrone; Female; Human

1985
Leydig cell function in men with gonadotrophin-producing testicular tumors.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:4

    Topics: Adult; Choriocarcinoma; Chorionic Gonadotropin; Chromatography, Gas; Dehydroepiandrosterone; Electro

1970
Estrogen production and its origin in men with gonadotropin-producing neoplasms.
    The Journal of clinical endocrinology and metabolism, 1974, Volume: 39, Issue:1

    Topics: Adult; Aged; Choriocarcinoma; Dehydroepiandrosterone; Estradiol; Estrone; Hormones, Ectopic; Humans;

1974
Estrogen production by trophoblastic tumors in tissue culture.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:1

    Topics: 17-Ketosteroids; Androstanes; Cell Line; Choriocarcinoma; Chromatography; Culture Techniques; Dehydr

1972
Dissimilar isotopic ratios in urinary estrogens following simultaneous injection of delta-4-androstenedione-14C and estrone-6,7-3H.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 36, Issue:1

    Topics: 17-Ketosteroids; Aged; Androstanes; Carbon Isotopes; Carcinoma; Choriocarcinoma; Endometrium; Estrad

1973
[Enzymes of steroid metabolism in human blood. II. Determination of 17-beta-hydroxysteroid: NAD(P)oxidoreductase in human plasma under physiological and pathological conditions].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1970, Sep-08, Volume: 7, Issue:5

    Topics: Abortion, Threatened; Blood Group Incompatibility; Chemistry, Clinical; Choriocarcinoma; Chromatogra

1970
Hormonal changes in urine and plasma by hormone-producing testicular tumors before and after treatment.
    Acta endocrinologica. Supplementum, 1971, Volume: 152

    Topics: Choriocarcinoma; Dysgerminoma; Estradiol; Estriol; Estrone; Gonadotropins; Humans; Male; Progesteron

1971
Clonal lines of human choriocarcinoma cells in culture.
    Acta endocrinologica. Supplementum, 1971, Volume: 153

    Topics: Animals; Biological Assay; Carbon Isotopes; Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Clon

1971
Quantitative studies of tissue uptake and disposition of hormones.
    Acta endocrinologica. Supplementum, 1971, Volume: 153

    Topics: Adenocarcinoma; Amnion; Androstanes; Animals; Autoradiography; Carbon Isotopes; Choriocarcinoma; Chr

1971
Urinary excretion of estrogens in women with hydatidiform mole and choriocarcinoma.
    Obstetrics and gynecology, 1970, Volume: 36, Issue:5

    Topics: Choriocarcinoma; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Hydatidiform Mole; Pregnanc

1970