estrone has been researched along with Chemical and Drug Induced Liver Injury in 15 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
| "Troglitazone is a thiazolidinedione insulin sensitizer drug that is metabolized mainly to a sulfate conjugate (M-1) in humans." | 1.32 | Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: implications for understanding troglitazone hepatotoxicity. ( Goto, A; Nakajima, M; Nezu, J; Nozawa, T; Sugiura, S; Tamai, I; Tsuji, A; Yokoi, T, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (53.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Greene, N | 1 |
| Fisk, L | 1 |
| Naven, RT | 1 |
| Note, RR | 1 |
| Patel, ML | 1 |
| Pelletier, DJ | 1 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Warner, DJ | 1 |
| Chen, H | 1 |
| Cantin, LD | 1 |
| Kenna, JG | 1 |
| Stahl, S | 1 |
| Walker, CL | 1 |
| Noeske, T | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| MATSUDA, A | 1 |
| Nozawa, T | 1 |
| Sugiura, S | 1 |
| Nakajima, M | 1 |
| Goto, A | 1 |
| Yokoi, T | 1 |
| Nezu, J | 1 |
| Tsuji, A | 1 |
| Tamai, I | 1 |
| Kulcsár, A | 1 |
| Kulcsár-Gergely, J | 1 |
| Udvardy, M | 1 |
| del Pino, VL | 1 |
| Bolt, HM | 2 |
| Lopez del Pino, V | 1 |
| Naeim, F | 1 |
| Copper, PH | 1 |
| Semion, AA | 1 |
| Tokar, VI | 1 |
| Potapenko, OV | 1 |
| Naugolnikh, EZ | 1 |
| Wenzel, M | 1 |
| Blum, KU | 1 |
| Kraas, E | 1 |
| Czeizel, E | 1 |
| Palkovits, M | 1 |
| Palkovich, I | 1 |
1 review available for estrone and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
14 other studies available for estrone and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
[STUDIES ON ESTROGEN METABOLISM IN THE RABBIT].
Topics: Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chromatography; Estradiol; E | 1964 |
Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: implications for understanding troglitazone hepatotoxicity.
Topics: Biological Transport, Active; Chemical and Drug Induced Liver Injury; Chromans; Cloning, Molecular; | 2004 |
Sex differences and sex hormones in experimental liver injury.
Topics: Animals; Biotransformation; Carbon Tetrachloride Poisoning; Castration; Chemical and Drug Induced Li | 1979 |
[Time course of thioacetamide-induced changes in estrogen metabolism in the rat liver].
Topics: Acetamides; Animals; Chemical and Drug Induced Liver Injury; Cytochromes; Estradiol; Estrone; In Vit | 1976 |
[The thioacetamide-poisoned rat as an animal experimental model for endocrinological studies of estrogen metabolism in chronic liver injury)].
Topics: Acetamides; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Chemical and Drug Induced Liver | 1975 |
Peliosis hepatis. Possible etiologic role of anabolic steroids.
Topics: Adult; Aged; Autopsy; Chemical and Drug Induced Liver Injury; Cytomegalovirus; Estrone; Female; Fluo | 1973 |
Metabolism of steroids in fluorosis. 2. Oestrone loading test in male patients with fluorine liver damage.
Topics: Adult; Chemical and Drug Induced Liver Injury; Estradiol; Estriol; Estrone; Fluorine; Humans; Liver | 1971 |
[Inactivation of estradiol by oxidation following liver damage in rats and in patients with liver diseases].
Topics: Aged; Amides; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Estra | 1968 |
[Effect of natural estrogens on the function of the healthy and damaged liver of rats].
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Estradiol; Estriol; | 1964 |