estrone has been researched along with Cell Transformation, Neoplastic in 22 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serum and urine were collected from 65 breast cancer patients and 36 controls after an overnight fast." | 5.30 | Urinary 2/16 alpha-hydroxyestrone ratio: correlation with serum insulin-like growth factor binding protein-3 and a potential biomarker of breast cancer risk. ( Foo, SC; Ho, GH; Ji, CY; Luo, XW; Ng, EH, 1998) |
| "Some estrogen metabolites induced chromosome aberrations in SHE cells following treatment for 24 hr." | 1.31 | Involvement of genotoxic effects in the initiation of estrogen-induced cellular transformation: studies using Syrian hamster embryo cells treated with 17beta-estradiol and eight of its metabolites. ( Barrett, JC; Tamura, Y; Tsutsui, T; Yagi, E, 2000) |
| "Normal anterior pituitaries and prolactinomas of female Wistar rats were dissociated enzymatically and mechanically, then cultured on collagen-treated plastic dishes." | 1.31 | Functional membrane changes due to tumor induction in rat pituitary cell cultures. ( Gálfi, M; Gáspár, L; Juhász, A; Julesz, J; Khalil, WK; Molnár, J; Valkusz, Z, 2000) |
| "Serum and urine were collected from 65 breast cancer patients and 36 controls after an overnight fast." | 1.30 | Urinary 2/16 alpha-hydroxyestrone ratio: correlation with serum insulin-like growth factor binding protein-3 and a potential biomarker of breast cancer risk. ( Foo, SC; Ho, GH; Ji, CY; Luo, XW; Ng, EH, 1998) |
| "Prolactinomas were induced by chronic estrone acetate treatment in female Wistar rats in vivo." | 1.30 | Surface changes and hormone production in pituitary cells during tumorigenesis. ( Galfi, M; Gáspár, L; Julesz, J; Khalil, WK; Szalai, G, 1999) |
| "The presence of PSA in breast cancers is associated with the presence of steroid-hormone receptors and may be a favourable prognostic indicator." | 1.29 | Prostate-specific antigen in breast cyst fluid: possible role of prostate-specific antigen in hormone-dependent breast cancer. ( Erbas, H; Lai, LC; Lennard, TW; Peaston, RT, 1996) |
| "The action of E2 metabolites on tumorigenic transformation, however, is poorly understood." | 1.28 | Induction by estrogen metabolite 16 alpha-hydroxyestrone of genotoxic damage and aberrant proliferation in mouse mammary epithelial cells. ( Bradlow, HL; Osborne, MP; Suto, A; Telang, NT; Wong, GY, 1992) |
| "Among women with 46,XY gonadal dysgenesis, there is a high incidence of gonadal tumors." | 1.27 | 46,XY gonadal dysgenesis: is oncogenesis related to H-Y phenotype or breast development? ( Kulin, HE; Monsaert, RP; Stumpf, PG; Wachtel, SS; Warner, BA, 1985) |
| "Infection of human foreskin cells (D-550) by the Snyder-Theilen strain of feline sarcoma virus produced small but countable foci and demonstrated "single-hit" dose-response kinetics." | 1.26 | Influence of glucocorticoid, estrogen, and androgen hormones on transformation of human cells in vitro by feline sarcoma virus. ( Blakeslee, JR; Milo, GE; Olsen, RG; Schaller, JP; Yohn, DS, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (31.82) | 18.7374 |
| 1990's | 7 (31.82) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Samavat, H | 1 |
| Kurzer, MS | 1 |
| Hirose, Y | 1 |
| Tsutsui, TW | 1 |
| Ohno, M | 1 |
| Barrett, JC | 3 |
| Tsutsui, T | 3 |
| Zhu, BT | 1 |
| Bui, QD | 1 |
| Weisz, J | 1 |
| Liehr, JG | 1 |
| Newfield, L | 1 |
| Bradlow, HL | 3 |
| Sepkovic, DW | 1 |
| Auborn, K | 1 |
| Ho, GH | 1 |
| Luo, XW | 1 |
| Ji, CY | 1 |
| Foo, SC | 1 |
| Ng, EH | 1 |
| Singhal, H | 1 |
| Guo, L | 1 |
| Mittelman, A | 1 |
| Tiwari, RK | 1 |
| Tamura, Y | 1 |
| Yagi, E | 2 |
| Pisha, E | 1 |
| Lui, X | 1 |
| Constantinou, AI | 1 |
| Bolton, JL | 1 |
| Telang, NT | 1 |
| Suto, A | 1 |
| Wong, GY | 1 |
| Osborne, MP | 1 |
| Eliassen, AH | 1 |
| Spiegelman, D | 1 |
| Xu, X | 1 |
| Keefer, LK | 1 |
| Veenstra, TD | 1 |
| Barbieri, RL | 1 |
| Willett, WC | 1 |
| Hankinson, SE | 1 |
| Ziegler, RG | 1 |
| Ohtaki, S | 1 |
| Lai, LC | 1 |
| Erbas, H | 1 |
| Lennard, TW | 1 |
| Peaston, RT | 1 |
| Khalil, WK | 2 |
| Gáspár, L | 2 |
| Szalai, G | 1 |
| Julesz, J | 2 |
| Galfi, M | 2 |
| Valkusz, Z | 1 |
| Juhász, A | 1 |
| Molnár, J | 1 |
| Carruba, G | 1 |
| Webber, MM | 1 |
| Quader, ST | 1 |
| Amoroso, M | 1 |
| Cocciadiferro, L | 1 |
| Saladino, F | 1 |
| Trosko, JE | 1 |
| Castagnetta, LA | 1 |
| Vanderpool, EA | 1 |
| Roane, P | 1 |
| Turner, W | 1 |
| Schaller, JP | 2 |
| Milo, GE | 2 |
| Blakeslee, JR | 1 |
| Olsen, RG | 1 |
| Yohn, DS | 2 |
| Warner, BA | 1 |
| Monsaert, RP | 1 |
| Stumpf, PG | 1 |
| Kulin, HE | 1 |
| Wachtel, SS | 1 |
| Sonnenschein, C | 1 |
| Weiller, S | 1 |
| Farookhi, R | 1 |
| Soto, AM | 1 |
| Fong, CK | 1 |
| Ledinko, N | 1 |
1 review available for estrone and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Estrogen metabolism and breast cancer.
Topics: Breast Neoplasms; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Estradiol; Estrog | 2015 |
21 other studies available for estrone and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Effects of a catechol-O-methyltransferase inhibitor on catechol estrogen-induced cellular transformation, chromosome aberrations and apoptosis in Syrian hamster embryo cells.
Topics: Animals; Apoptosis; Benzophenones; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibi | 2007 |
Conversion of estrone to 2- and 4-hydroxyestrone by hamster kidney and liver microsomes: implications for the mechanism of estrogen-induced carcinogenesis.
Topics: Animals; Catechol O-Methyltransferase; Cell Transformation, Neoplastic; Chromatography, Gas; Criceti | 1994 |
Estrogen metabolism and the malignant potential of human papillomavirus immortalized keratinocytes.
Topics: Aryl Hydrocarbon Hydroxylases; Cell Line; Cell Transformation, Neoplastic; Cytochrome P-450 CYP2C8; | 1998 |
Urinary 2/16 alpha-hydroxyestrone ratio: correlation with serum insulin-like growth factor binding protein-3 and a potential biomarker of breast cancer risk.
Topics: Age Factors; Anticarcinogenic Agents; Biomarkers, Tumor; Body Mass Index; Breast Neoplasms; Cell Tra | 1998 |
Endocrine characteristics of human breast epithelial cells, MCF-10F.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aromatase; Aryl Hydrocarbon Hydroxylases; Breast; Breast Neoplasms | 1999 |
Involvement of genotoxic effects in the initiation of estrogen-induced cellular transformation: studies using Syrian hamster embryo cells treated with 17beta-estradiol and eight of its metabolites.
Topics: Aneuploidy; Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Abe | 2000 |
Evidence that a metabolite of equine estrogens, 4-hydroxyequilenin, induces cellular transformation in vitro.
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA Damage; Epidermal Cells; Epide | 2001 |
The ability of four catechol estrogens of 17beta-estradiol and estrone to induce DNA adducts in Syrian hamster embryo fibroblasts.
Topics: Animals; Antioxidants; Ascorbic Acid; Cell Survival; Cell Transformation, Neoplastic; Cricetinae; DN | 2001 |
Induction by estrogen metabolite 16 alpha-hydroxyestrone of genotoxic damage and aberrant proliferation in mouse mammary epithelial cells.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; DNA Repair; Estradiol; Female; Hydroxyestro | 1992 |
Urinary estrogens and estrogen metabolites and subsequent risk of breast cancer among premenopausal women.
Topics: Adult; Breast Neoplasms; Case-Control Studies; Cell Transformation, Neoplastic; Chromatography, Liqu | 2012 |
An immune- and hormone-dependent phase during the latency period of SV40 oncogenesis in Syrian hamsters.
Topics: Animals; Cell Transformation, Neoplastic; Cricetinae; Cyclophosphamide; Estrone; Female; Immunosuppr | 1981 |
Prostate-specific antigen in breast cyst fluid: possible role of prostate-specific antigen in hormone-dependent breast cancer.
Topics: 17-Hydroxysteroid Dehydrogenases; Adenocarcinoma; Body Fluids; Breast Neoplasms; Cell Division; Cell | 1996 |
Surface changes and hormone production in pituitary cells during tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acridines; Adrenocorticotropic Hormone; alpha-MSH; Animals; Carcin | 1999 |
Functional membrane changes due to tumor induction in rat pituitary cell cultures.
Topics: Acridines; Animals; Carcinogens; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cy | 2000 |
Regulation of cell-to-cell communication in non-tumorigenic and malignant human prostate epithelial cells.
Topics: Cell Communication; Cell Transformation, Neoplastic; Colforsin; Connexins; Epithelial Cells; Estrone | 2002 |
Enhancement of adenovirus transformation by pretreatment of rat embryo cells with estrogenic and androgenic hormones.
Topics: Adenoviruses, Human; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cholester | 1979 |
Influence of glucocorticoid, estrogen, and androgen hormones on transformation of human cells in vitro by feline sarcoma virus.
Topics: Aldosterone; Androgens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells | 1976 |
46,XY gonadal dysgenesis: is oncogenesis related to H-Y phenotype or breast development?
Topics: Adolescent; Adult; Breast; Cell Transformation, Neoplastic; Child; Dihydrotestosterone; Dysgerminoma | 1985 |
Characterization of an estrogen-sensitive cell line established from normal rat endometrium.
Topics: Adenocarcinoma; Animals; Binding Sites; Cell Division; Cell Line; Cell Nucleus; Cell Transformation, | 1974 |
Enhancement by estrogens of adenovirus or spontaneous transformation of hamster cell cultures.
Topics: Adenoviridae; Animals; Cell Transformation, Neoplastic; Cricetinae; Culture Techniques; Cytopathogen | 1970 |
Hormonal modification of adenovirus transformation of hamster cells in vitro.
Topics: Adenoviridae; Aldosterone; Animals; Cattle; Cell Division; Cell Survival; Cell Transformation, Neopl | 1972 |