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estrone and Cell Transformation, Neoplastic

estrone has been researched along with Cell Transformation, Neoplastic in 22 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research Excerpts

ExcerptRelevanceReference
"Serum and urine were collected from 65 breast cancer patients and 36 controls after an overnight fast."5.30Urinary 2/16 alpha-hydroxyestrone ratio: correlation with serum insulin-like growth factor binding protein-3 and a potential biomarker of breast cancer risk. ( Foo, SC; Ho, GH; Ji, CY; Luo, XW; Ng, EH, 1998)
"Some estrogen metabolites induced chromosome aberrations in SHE cells following treatment for 24 hr."1.31Involvement of genotoxic effects in the initiation of estrogen-induced cellular transformation: studies using Syrian hamster embryo cells treated with 17beta-estradiol and eight of its metabolites. ( Barrett, JC; Tamura, Y; Tsutsui, T; Yagi, E, 2000)
"Normal anterior pituitaries and prolactinomas of female Wistar rats were dissociated enzymatically and mechanically, then cultured on collagen-treated plastic dishes."1.31Functional membrane changes due to tumor induction in rat pituitary cell cultures. ( Gálfi, M; Gáspár, L; Juhász, A; Julesz, J; Khalil, WK; Molnár, J; Valkusz, Z, 2000)
"Serum and urine were collected from 65 breast cancer patients and 36 controls after an overnight fast."1.30Urinary 2/16 alpha-hydroxyestrone ratio: correlation with serum insulin-like growth factor binding protein-3 and a potential biomarker of breast cancer risk. ( Foo, SC; Ho, GH; Ji, CY; Luo, XW; Ng, EH, 1998)
"Prolactinomas were induced by chronic estrone acetate treatment in female Wistar rats in vivo."1.30Surface changes and hormone production in pituitary cells during tumorigenesis. ( Galfi, M; Gáspár, L; Julesz, J; Khalil, WK; Szalai, G, 1999)
"The presence of PSA in breast cancers is associated with the presence of steroid-hormone receptors and may be a favourable prognostic indicator."1.29Prostate-specific antigen in breast cyst fluid: possible role of prostate-specific antigen in hormone-dependent breast cancer. ( Erbas, H; Lai, LC; Lennard, TW; Peaston, RT, 1996)
"The action of E2 metabolites on tumorigenic transformation, however, is poorly understood."1.28Induction by estrogen metabolite 16 alpha-hydroxyestrone of genotoxic damage and aberrant proliferation in mouse mammary epithelial cells. ( Bradlow, HL; Osborne, MP; Suto, A; Telang, NT; Wong, GY, 1992)
"Among women with 46,XY gonadal dysgenesis, there is a high incidence of gonadal tumors."1.2746,XY gonadal dysgenesis: is oncogenesis related to H-Y phenotype or breast development? ( Kulin, HE; Monsaert, RP; Stumpf, PG; Wachtel, SS; Warner, BA, 1985)
"Infection of human foreskin cells (D-550) by the Snyder-Theilen strain of feline sarcoma virus produced small but countable foci and demonstrated "single-hit" dose-response kinetics."1.26Influence of glucocorticoid, estrogen, and androgen hormones on transformation of human cells in vitro by feline sarcoma virus. ( Blakeslee, JR; Milo, GE; Olsen, RG; Schaller, JP; Yohn, DS, 1976)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19907 (31.82)18.7374
1990's7 (31.82)18.2507
2000's6 (27.27)29.6817
2010's2 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Samavat, H1
Kurzer, MS1
Hirose, Y1
Tsutsui, TW1
Ohno, M1
Barrett, JC3
Tsutsui, T3
Zhu, BT1
Bui, QD1
Weisz, J1
Liehr, JG1
Newfield, L1
Bradlow, HL3
Sepkovic, DW1
Auborn, K1
Ho, GH1
Luo, XW1
Ji, CY1
Foo, SC1
Ng, EH1
Singhal, H1
Guo, L1
Mittelman, A1
Tiwari, RK1
Tamura, Y1
Yagi, E2
Pisha, E1
Lui, X1
Constantinou, AI1
Bolton, JL1
Telang, NT1
Suto, A1
Wong, GY1
Osborne, MP1
Eliassen, AH1
Spiegelman, D1
Xu, X1
Keefer, LK1
Veenstra, TD1
Barbieri, RL1
Willett, WC1
Hankinson, SE1
Ziegler, RG1
Ohtaki, S1
Lai, LC1
Erbas, H1
Lennard, TW1
Peaston, RT1
Khalil, WK2
Gáspár, L2
Szalai, G1
Julesz, J2
Galfi, M2
Valkusz, Z1
Juhász, A1
Molnár, J1
Carruba, G1
Webber, MM1
Quader, ST1
Amoroso, M1
Cocciadiferro, L1
Saladino, F1
Trosko, JE1
Castagnetta, LA1
Vanderpool, EA1
Roane, P1
Turner, W1
Schaller, JP2
Milo, GE2
Blakeslee, JR1
Olsen, RG1
Yohn, DS2
Warner, BA1
Monsaert, RP1
Stumpf, PG1
Kulin, HE1
Wachtel, SS1
Sonnenschein, C1
Weiller, S1
Farookhi, R1
Soto, AM1
Fong, CK1
Ledinko, N1

Reviews

1 review available for estrone and Cell Transformation, Neoplastic

ArticleYear
Estrogen metabolism and breast cancer.
    Cancer letters, 2015, Jan-28, Volume: 356, Issue:2 Pt A

    Topics: Breast Neoplasms; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Estradiol; Estrog

2015

Other Studies

21 other studies available for estrone and Cell Transformation, Neoplastic

ArticleYear
Effects of a catechol-O-methyltransferase inhibitor on catechol estrogen-induced cellular transformation, chromosome aberrations and apoptosis in Syrian hamster embryo cells.
    International journal of cancer, 2007, Apr-15, Volume: 120, Issue:8

    Topics: Animals; Apoptosis; Benzophenones; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibi

2007
Conversion of estrone to 2- and 4-hydroxyestrone by hamster kidney and liver microsomes: implications for the mechanism of estrogen-induced carcinogenesis.
    Endocrinology, 1994, Volume: 135, Issue:5

    Topics: Animals; Catechol O-Methyltransferase; Cell Transformation, Neoplastic; Chromatography, Gas; Criceti

1994
Estrogen metabolism and the malignant potential of human papillomavirus immortalized keratinocytes.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1998, Volume: 217, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Cell Line; Cell Transformation, Neoplastic; Cytochrome P-450 CYP2C8;

1998
Urinary 2/16 alpha-hydroxyestrone ratio: correlation with serum insulin-like growth factor binding protein-3 and a potential biomarker of breast cancer risk.
    Annals of the Academy of Medicine, Singapore, 1998, Volume: 27, Issue:2

    Topics: Age Factors; Anticarcinogenic Agents; Biomarkers, Tumor; Body Mass Index; Breast Neoplasms; Cell Tra

1998
Endocrine characteristics of human breast epithelial cells, MCF-10F.
    Hormone research, 1999, Volume: 52, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aromatase; Aryl Hydrocarbon Hydroxylases; Breast; Breast Neoplasms

1999
Involvement of genotoxic effects in the initiation of estrogen-induced cellular transformation: studies using Syrian hamster embryo cells treated with 17beta-estradiol and eight of its metabolites.
    International journal of cancer, 2000, Apr-01, Volume: 86, Issue:1

    Topics: Aneuploidy; Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Abe

2000
Evidence that a metabolite of equine estrogens, 4-hydroxyequilenin, induces cellular transformation in vitro.
    Chemical research in toxicology, 2001, Volume: 14, Issue:1

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA Damage; Epidermal Cells; Epide

2001
The ability of four catechol estrogens of 17beta-estradiol and estrone to induce DNA adducts in Syrian hamster embryo fibroblasts.
    Carcinogenesis, 2001, Volume: 22, Issue:9

    Topics: Animals; Antioxidants; Ascorbic Acid; Cell Survival; Cell Transformation, Neoplastic; Cricetinae; DN

2001
Induction by estrogen metabolite 16 alpha-hydroxyestrone of genotoxic damage and aberrant proliferation in mouse mammary epithelial cells.
    Journal of the National Cancer Institute, 1992, Apr-15, Volume: 84, Issue:8

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; DNA Repair; Estradiol; Female; Hydroxyestro

1992
Urinary estrogens and estrogen metabolites and subsequent risk of breast cancer among premenopausal women.
    Cancer research, 2012, Feb-01, Volume: 72, Issue:3

    Topics: Adult; Breast Neoplasms; Case-Control Studies; Cell Transformation, Neoplastic; Chromatography, Liqu

2012
An immune- and hormone-dependent phase during the latency period of SV40 oncogenesis in Syrian hamsters.
    Advances in experimental medicine and biology, 1981, Volume: 134

    Topics: Animals; Cell Transformation, Neoplastic; Cricetinae; Cyclophosphamide; Estrone; Female; Immunosuppr

1981
Prostate-specific antigen in breast cyst fluid: possible role of prostate-specific antigen in hormone-dependent breast cancer.
    International journal of cancer, 1996, Jun-11, Volume: 66, Issue:6

    Topics: 17-Hydroxysteroid Dehydrogenases; Adenocarcinoma; Body Fluids; Breast Neoplasms; Cell Division; Cell

1996
Surface changes and hormone production in pituitary cells during tumorigenesis.
    Journal of experimental & clinical cancer research : CR, 1999, Volume: 18, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acridines; Adrenocorticotropic Hormone; alpha-MSH; Animals; Carcin

1999
Functional membrane changes due to tumor induction in rat pituitary cell cultures.
    Journal of experimental & clinical cancer research : CR, 2000, Volume: 19, Issue:4

    Topics: Acridines; Animals; Carcinogens; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cy

2000
Regulation of cell-to-cell communication in non-tumorigenic and malignant human prostate epithelial cells.
    The Prostate, 2002, Feb-01, Volume: 50, Issue:2

    Topics: Cell Communication; Cell Transformation, Neoplastic; Colforsin; Connexins; Epithelial Cells; Estrone

2002
Enhancement of adenovirus transformation by pretreatment of rat embryo cells with estrogenic and androgenic hormones.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1979, Volume: 160, Issue:4

    Topics: Adenoviruses, Human; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cholester

1979
Influence of glucocorticoid, estrogen, and androgen hormones on transformation of human cells in vitro by feline sarcoma virus.
    Cancer research, 1976, Volume: 36, Issue:6

    Topics: Aldosterone; Androgens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells

1976
46,XY gonadal dysgenesis: is oncogenesis related to H-Y phenotype or breast development?
    Human genetics, 1985, Volume: 69, Issue:1

    Topics: Adolescent; Adult; Breast; Cell Transformation, Neoplastic; Child; Dihydrotestosterone; Dysgerminoma

1985
Characterization of an estrogen-sensitive cell line established from normal rat endometrium.
    Cancer research, 1974, Volume: 34, Issue:11

    Topics: Adenocarcinoma; Animals; Binding Sites; Cell Division; Cell Line; Cell Nucleus; Cell Transformation,

1974
Enhancement by estrogens of adenovirus or spontaneous transformation of hamster cell cultures.
    Cancer research, 1970, Volume: 30, Issue:3

    Topics: Adenoviridae; Animals; Cell Transformation, Neoplastic; Cricetinae; Culture Techniques; Cytopathogen

1970
Hormonal modification of adenovirus transformation of hamster cells in vitro.
    Cancer research, 1972, Volume: 32, Issue:11

    Topics: Adenoviridae; Aldosterone; Animals; Cattle; Cell Division; Cell Survival; Cell Transformation, Neopl

1972