Page last updated: 2024-11-07

estrone and Carcinogenesis

estrone has been researched along with Carcinogenesis in 8 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.

Research Excerpts

ExcerptRelevanceReference
"Accurately quantifying parent estrogens (PE) estrone (E1) and estradiol (E2) and their metabolites (EM) within breast tissue and serum may permit detailed investigations of their contributions to breast carcinogenesis among BRCA1/2 mutation carriers."3.80Circulating estrogens and estrogens within the breast among postmenopausal BRCA1/2 mutation carriers. ( Falk, RT; Gail, MH; Gierach, GL; Greene, MH; Guttmann, A; Loud, JT; Nichols, K; Veenstra, TD; Xu, X, 2014)
"Although endometrial cancer is clearly influenced by hormonal factors, few epidemiologic studies have investigated the role of endogenous estrogens or especially estrogen metabolites."1.43Serum Estrogens and Estrogen Metabolites and Endometrial Cancer Risk among Postmenopausal Women. ( Anderson, GL; Brinton, LA; Falk, RT; Felix, AS; Fuhrman, BJ; Gass, ML; Kuller, LH; Pfeiffer, RM; Rohan, TE; Strickler, HD; Trabert, B; Wentzensen, N; Xu, X, 2016)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Cavalieri, E1
Rogan, E1
Slade, L1
Pulinilkunnil, T1
Tian, W1
Teng, F1
Zhao, J1
Gao, J1
Gao, C1
Sun, D1
Liu, G1
Zhang, Y1
Yu, S1
Zhang, W1
Wang, Y1
Xue, F1
Loud, JT1
Gierach, GL1
Veenstra, TD1
Falk, RT2
Nichols, K1
Guttmann, A1
Xu, X2
Greene, MH1
Gail, MH1
Brinton, LA1
Trabert, B1
Anderson, GL1
Felix, AS1
Fuhrman, BJ1
Gass, ML1
Kuller, LH1
Pfeiffer, RM1
Rohan, TE1
Strickler, HD1
Wentzensen, N1
VACZY, L1
JULL, JW1
PICCO, A1
GNAVI, M1
PANSA, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer[NCT00040222]377 participants (Actual)Observational2002-07-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for estrone and Carcinogenesis

ArticleYear
The 3,4-Quinones of Estrone and Estradiol Are the Initiators of Cancer whereas Resveratrol and
    International journal of molecular sciences, 2021, Jul-30, Volume: 22, Issue:15

    Topics: Acetylcysteine; Animals; Antioxidants; Carcinogenesis; DNA Adducts; Estradiol; Estrogens; Estrone; H

2021
The MiTF/TFE Family of Transcription Factors: Master Regulators of Organelle Signaling, Metabolism, and Stress Adaptation.
    Molecular cancer research : MCR, 2017, Volume: 15, Issue:12

    Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carcinogenesis; Energy Metabolism; Estr

2017

Other Studies

6 other studies available for estrone and Carcinogenesis

ArticleYear
Estrogen and insulin synergistically promote type 1 endometrial cancer progression.
    Cancer biology & therapy, 2017, Dec-02, Volume: 18, Issue:12

    Topics: Aged; Apoptosis; Carcinogenesis; Cell Cycle; Cell Proliferation; Endometrial Neoplasms; Endometrium;

2017
Circulating estrogens and estrogens within the breast among postmenopausal BRCA1/2 mutation carriers.
    Breast cancer research and treatment, 2014, Volume: 143, Issue:3

    Topics: Adult; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Carcinogenesis; Estradiol; Estrone; Female; H

2014
Serum Estrogens and Estrogen Metabolites and Endometrial Cancer Risk among Postmenopausal Women.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2016, Volume: 25, Issue:7

    Topics: Aged; Biomarkers, Tumor; Carcinogenesis; Case-Control Studies; Endometrial Neoplasms; Estradiol; Est

2016
[Interrelationship between folliculin, castration, and carcinogenesis].
    Magyar noorvosok lapja, 1955, Volume: 18, Issue:3

    Topics: Animals; Carcinogenesis; Castration; Estrogens; Estrone; Humans; Male; Neoplasms, Experimental; Orch

1955
THE EFFECTS OF HORMONAL ENVIRONMENT ON MAMMARY CARCINOGENESIS IN C3HB MICE BY 1,2:5,6-DIBENZANTHRACENE.
    British journal of cancer, 1964, Volume: 13

    Topics: Animals; Benz(a)Anthracenes; Breast Neoplasms; Carcinogenesis; Estrone; Female; Humans; Mammary Neop

1964
[Research on the promoting action of folliculin in the double mechanism of carcinogenesis of the uterus and vagina in ovariectomized rats].
    Il Cancro, 1961, Volume: 14

    Topics: Animals; Carcinogenesis; Estrogens; Estrone; Female; Humans; Neoplasms, Experimental; Ovary; Rats; U

1961