Page last updated: 2024-11-07

estrone and Cancer of Prostate

estrone has been researched along with Cancer of Prostate in 79 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Research Excerpts

ExcerptRelevanceReference
"Plasma concentrations of estramustine phosphate and its major metabolites were measured in patients with prostatic carcinoma treated with increasing oral doses, 70-650 mg/day, of estramustine phosphate (Estracyt)."7.66Plasma concentrations of estramustine phosphate and its major metabolites in patients with prostatic carcinoma treated with different doses of estramustine phosphate (Estracyt). ( Forshell, GP; Fritjofsson, A; Gunnarsson, PO; Norlén, BJ, 1981)
"Seeking insight into the possible role of estrogens in prostate cancer (PCa) evolution, we assayed serum E2, estrone (E1), and estrone sulfate (E1S) in 349 PCa and 100 benign prostatic hyperplasia (BPH) patients, and in 208 control subjects in the same age range (50-74 years)."3.74Estrone sulfate (E1S), a prognosis marker for tumor aggressiveness in prostate cancer (PCa). ( Abbou, CC; Allory, Y; Cussenot, O; de la Taille, A; Fiet, J; Galons, H; Giton, F; Loric, S; Raynaud, JP; Soyeux, P; Vacherot, F, 2008)
"Plasma and tumour concentrations of estramustine, estromustine, estradiol and estrone, the major metabolites of estramustine phosphate (estracyt), were determined in patients with prostatic carcinoma treated between one and nine years with repeated oral doses of estracyt (560 to 840 mg."3.67Uptake of estramustine phosphate (estracyt) metabolites in prostatic cancer. ( Andersson, SB; Björk, P; Fritjofsson, A; Gunnarsson, PO; Norlén, BJ, 1988)
"Cortisol, 17-hydroxyprogesterone (17-OH-P), progesterone, testosterone, 5 alpha-dihydrotestosterone (DHT), estrone (E1) and estradiol (E2) were determined by RIA after chromatographic separation of steroids on Sephadex LH-20 columns, in 54 hospitalized patients with benign prostatic hyperplasia (BPH) and in 32 hospitalized patients with prostatic carcinoma (PCA) (T34, N01, M01)."3.66Plasma steroids in benign prostatic hypertrophy and carcinoma of the prostate. ( Drafta, D; Neacşu, E; Proca, E; Schindler, AE; Stroe, E; Zamfir, V, 1982)
"Plasma concentrations of estramustine phosphate and its major metabolites were measured in patients with prostatic carcinoma treated with increasing oral doses, 70-650 mg/day, of estramustine phosphate (Estracyt)."3.66Plasma concentrations of estramustine phosphate and its major metabolites in patients with prostatic carcinoma treated with different doses of estramustine phosphate (Estracyt). ( Forshell, GP; Fritjofsson, A; Gunnarsson, PO; Norlén, BJ, 1981)
"The etiology of prostate cancer remains elusive, although steroid hormones probably play a role."2.76Repeat polymorphisms in estrogen metabolism genes and prostate cancer risk: results from the Prostate Cancer Prevention Trial. ( Ambrosone, CB; Goodman, PJ; Hoque, A; Hsing, A; Kristal, AR; Lippman, SM; Neuhouser, ML; Platz, EA; Reichardt, JK; Santella, RM; Stanczyk, FZ; Tang, L; Tangen, CM; Thompson, IM; Till, C; Wu, Y; Yao, S, 2011)
"Patients aged < 60 years with prostate cancer had significantly elevated levels of total testosterone and unconjugated (E1) and total (tE1) oestrone while patients aged > or = 60 years had significantly elevated levels of total and non-SHBG-bound testosterone (NST)."2.68Testicular and adrenocortical function in men with prostatic cancer and in healthy age-matched controls. ( Carlström, K; Stege, R, 1997)
"To investigate prostate cancer (Pca) risk in relation to estrogen metabolism, expressed as urinary 2-hydroxyestrone (2-OHE1), 16alpha-hydroxyestrone (16alpha-OHE1) and 2-OHE1 to 16alpha-OHE1 ratio."2.45Urinary estrogen metabolites and prostate cancer: a case-control study and meta-analysis. ( Barba, M; Blandino, G; Gallucci, M; Grioni, S; Lauria, R; Malorni, L; Muti, P; Schünemann, HJ; Sperati, F; Stranges, S; Westerlind, KC; Yang, L, 2009)
"In castration-resistant prostate cancer patients, levels of androstenedione were significantly associated with testosterone level, while testosterone was the only steroid associated with dihydrotestosterone levels."1.72Extensive Alteration of Androgen Precursor Levels After Castration in Prostate Cancer Patients and Their Association With Active Androgen Level. ( Caron, P; Guillemette, C; Lacombe, L; Lévesque, É; Morin, F; Neveu, B; Pouliot, F; Rouleau, M; Toren, P; Turcotte, V, 2022)
"Risk of aggressive prostate cancer was strongly inversely associated with estradiol:testosterone ratio (OR4th quartile vs."1.40Sex steroid hormone metabolism in relation to risk of aggressive prostate cancer. ( Black, A; Brinton, LA; Chu, L; Cook, MB; Falk, RT; Grubb, RL; Hoover, RN; Hsing, AW; Meyer, T; Pinsky, PF; Veenstra, TD; Xu, X; Yu, K; Ziegler, RG, 2014)
"Finasteride reduces prostate cancer risk by blocking the conversion of testosterone to dihydrotestosterone."1.37Serum estrogen levels and prostate cancer risk in the prostate cancer prevention trial: a nested case-control study. ( Ambrosone, CB; Figg, WD; Goodman, PJ; Hoque, A; Hsing, AW; Kristal, AR; Lippman, SM; Neuhouser, ML; Parnes, HL; Platz, EA; Price, DK; Reichardt, JK; Santella, RM; Stanczyk, FZ; Tang, L; Tangen, CM; Thompson, IM; Till, C; Yao, S, 2011)
"Associations between incident prostate cancer and each sex hormone were evaluated using Cox proportional hazards regression models adjusted for age, race, study site, body mass index, and person-time."1.36Sex hormones and the risk of incident prostate cancer. ( Bauer, DC; Daniels, NA; Hoffman, AR; Nielson, CM, 2010)
"We recruited AA men attending prostate cancer screenings in and around Columbia, South Carolina."1.33Urinary estrogen metabolites, prostate specific antigen, and body mass index among African-American men in South Carolina. ( Boulware, RJ; Cunningham, JE; Fowke, JH; Hebert, JR; Hurley, TG; Kanwat, CP; Nitcheva, D; Sepkovic, DW; Teas, J, 2005)
"To analyze the association of prostate cancer risk with estrogen metabolism, expressed as the ratio of 2-hydroxyestrone (2-OHE1) to 16alpha-hydroxyestrone (16alpha-OHE1), in a case-control study conducted in Buffalo, NY, between 1998 and 2001."1.31Urinary estrogen metabolites and prostate cancer: a case-control study in the United States. ( Bradlow, L; Carruba, G; De Berry, J; Freudenheim, JL; Grimaldi, T; Hill, H; Muti, P; Schünemann, H; Westerlind, K; Wu, T, 2002)
"These data demonstrate that LNCaP prostate cancer cells contain a steryl sulfatase with properties similar to that found in human breast cancer cells, and that the activity of this enzyme can be blocked by known steryl sulfatase inhibitors."1.31Inhibition of steryl sulfatase activity in LNCaP human prostate cancer cells. ( Kabler, H; Li, PK; Sarap, J; Selcer, KW; Xiao, Z, 2002)
" In this study, total testosterone, estrone, estradiol, and sex hormone-binding globulin were not related to prostate cancer, but plasma androstenedione showed a positive dose-response gradient."1.28A prospective, population-based study of androstenedione, estrogens, and prostatic cancer. ( Barrett-Connor, E; Garland, C; Khaw, KT; McPhillips, JB; Wingard, DL, 1990)
"Estracyt is a new drug for treatment of prostatic cancer, which is a molecule combining estradiol and nornitrogen mustard by a carbamate link."1.27[Pharmacology and metabolism of a new therapeutic drug for prostatic cancer "Estracyt"]. ( Shida, K; Yamanaka, H, 1984)
"In these prostatic cancer patients, plasma androgen levels decreased, while estrogen levels increased."1.26Effect of diet on plasma and urinary hormones in South African black men with prostatic cancer. ( Garbaczewski, L; Hill, P; Walker, AR; Wynder, EL, 1982)
"Estrone levels were age invariant in both patients and controls, but the mean level in patients was markedly elevated (81 vs 47 pg/ml in controls; P less than 0."1.26Abnormal levels of plasma hormones in men with prostate cancer: evidence toward a "two-disease" theory. ( Freed, SZ; Fukushima, DK; Hellman, L; Kream, J; Levin, J; O'Connor, J; Rosenfeld, RS; Strain, GW; Whitmore, WS; Zumoff, B, 1982)
" The dosage of the drug was 750 mg."1.25Prostatic cancer and SCH-13521: II. Histological alterations and the pituitary gonadal axis. ( Daly, JJ; Griffin, PP; Irwin, RJ; Kliman, B; MacLaughlin, RA; Prout, GR, 1975)
"In patients with breast and prostate cancer hormone excretion patterns differ in a similar way from patterns in persons without cancer."1.24HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL. ( HOPKINS, CE; MARMORSTON, J; STERN, E; WEINER, JM, 1964)

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-199044 (55.70)18.7374
1990's9 (11.39)18.2507
2000's15 (18.99)29.6817
2010's9 (11.39)24.3611
2020's2 (2.53)2.80

Authors

AuthorsStudies
Emond, JP1
Lacombe, L2
Caron, P2
Turcotte, V2
Simonyan, D1
Aprikian, A1
Saad, F1
Carmel, M1
Chevalier, S1
Guillemette, C3
Lévesque, E2
Barba, M1
Yang, L1
Schünemann, HJ1
Sperati, F1
Grioni, S1
Stranges, S1
Westerlind, KC1
Blandino, G1
Gallucci, M1
Lauria, R1
Malorni, L1
Muti, P2
Westerlind, K1
Wu, T1
Grimaldi, T1
De Berry, J1
Schünemann, H1
Freudenheim, JL1
Hill, H1
Carruba, G2
Bradlow, L1
Day, JM1
Newman, SP1
Comninos, A1
Solomon, C1
Purohit, A1
Leese, MP1
Potter, BV2
Reed, MJ1
Mueck, AO1
Seeger, H1
Lippert, TH1
Teas, J1
Cunningham, JE1
Fowke, JH1
Nitcheva, D1
Kanwat, CP1
Boulware, RJ1
Sepkovic, DW1
Hurley, TG1
Hebert, JR1
Markushin, Y1
Gaikwad, N1
Zhang, H1
Kapke, P1
Rogan, EG1
Cavalieri, EL1
Trock, BJ1
Pavlovich, C1
Jankowiak, R1
Hamilton-Reeves, JM1
Rebello, SA1
Thomas, W1
Slaton, JW1
Kurzer, MS1
Rouleau, M1
Neveu, B1
Morin, F1
Toren, P1
Pouliot, F1
Black, A1
Pinsky, PF1
Grubb, RL1
Falk, RT1
Hsing, AW3
Chu, L1
Meyer, T1
Veenstra, TD1
Xu, X1
Yu, K1
Ziegler, RG1
Brinton, LA1
Hoover, RN1
Cook, MB1
Thomas, MP1
Schenk, JM1
Till, C3
Stanczyk, FZ3
Gong, Z1
Neuhouser, ML3
Reichardt, JK3
Hoque, AM1
Figg, WD2
Goodman, PJ3
Tangen, CM3
Thompson, IM3
Daniels, NA1
Nielson, CM1
Hoffman, AR1
Bauer, DC1
Thomas, JA1
Bañez, L1
Freedland, SJ1
Tong, da Y2
Wen, XQ1
Jin, Y2
Liu, ZW2
Sun, HY2
Zhou, FJ2
Wu, XY2
Yao, S2
Kristal, AR2
Platz, EA2
Tang, L2
Santella, RM2
Price, DK1
Parnes, HL1
Lippman, SM2
Ambrosone, CB2
Hoque, A2
Wu, Y1
Hsing, A1
Selcer, KW1
Kabler, H1
Sarap, J1
Xiao, Z1
Li, PK1
MASCHIO, C1
DUNNING, WF1
MAHONEY, SA1
PERSKY, L1
ZIMMERMANN, W1
BUESCHER, HK1
TAUPITZ, A1
THEWALT, K1
BRADSHAW, LR1
BAGNESS, JE1
PYRAH, LN1
RAPER, FP1
STERN, E3
HOPKINS, CE3
WEINER, JM2
MARMORSTON, J3
LOMBARDO, LJ1
MYERS, SM1
GIERSON, H1
ACEVEDO, HF1
GOLDZIEHER, JW1
DEVOS, R1
Nakamura, Y1
Suzuki, T1
Fukuda, T1
Ito, A1
Endo, M1
Moriya, T1
Arai, Y1
Sasano, H1
Giton, F1
de la Taille, A1
Allory, Y1
Galons, H1
Vacherot, F1
Soyeux, P1
Abbou, CC1
Loric, S1
Cussenot, O1
Raynaud, JP1
Fiet, J1
Belis, JA2
Coffey, DS1
Isaacs, JT1
Hill, P1
Wynder, EL2
Garbaczewski, L1
Walker, AR1
Drafta, D1
Proca, E1
Zamfir, V1
Schindler, AE1
Neacşu, E1
Stroe, E1
Sandberg, AA2
Forsgren, B1
Björk, P3
Gunnarsson, PO5
Forshell, GP2
Yamanaka, H1
Shida, K1
Rose, DP1
Laakso, K1
Sotarauta, M1
Kirdani, RY1
Karr, JP1
Murphy, GP1
Zumoff, B2
Levin, J2
Strain, GW1
Rosenfeld, RS1
O'Connor, J1
Freed, SZ2
Kream, J1
Whitmore, WS1
Fukushima, DK2
Hellman, L3
Meikle, AW1
Stanish, WM1
Ahluwalia, B1
Jackson, MA1
Jones, GW1
Williams, AO1
Rao, MS1
Rajguru, S1
Tarry, WF1
Fritjofsson, A2
Norlén, BJ2
Whitmore, WF1
Fishman, J2
Leinonen, P1
Hum, DW1
Bélanger, A1
Carlström, K3
Stege, R3
Mäkelä, S1
Poutanen, M1
Kostian, ML1
Lehtimäki, N1
Strauss, L1
Santti, R1
Vihko, R1
Walz, PH1
Edman, K1
Hartley-Asp, B1
Wang, LG1
Liu, XM1
Kreis, W1
Budman, DR1
Grande, M2
Pousette, A2
Faxén, M2
Penning, TM1
Burczynski, ME1
Jez, JM1
Lin, HK1
Ma, H1
Moore, M1
Ratnam, K1
Palackal, N1
Le Lain, R1
Nicholls, PJ1
Smith, HJ1
Maharlouie, FH1
Webber, MM1
Quader, ST1
Amoroso, M1
Cocciadiferro, L1
Saladino, F1
Trosko, JE1
Castagnetta, LA1
Nishikawa, G1
Wahren, B1
Schweikert, HU1
Steg, A1
Benoit, G1
Noble, RL3
Payne, AH1
Kelch, RP1
Musich, SS1
Halpern, ME1
Prout, GR1
Irwin, RJ1
Kliman, B1
Daly, JJ1
MacLaughlin, RA1
Griffin, PP1
de Launoit, Y1
Veilleux, R1
Dufour, M1
Simard, J1
Labrie, F1
Pusateri, DJ1
Roth, WT1
Ross, JK1
Shultz, TD1
Barrett-Connor, E1
Garland, C1
McPhillips, JB1
Khaw, KT1
Wingard, DL1
Davidsson, T1
Andersson, SB2
Backman, C1
Johansson, SA1
Rannikko, S1
Adlercreutz, H1
Haapiainen, R1
Huot, RI1
Shain, SA1
Carroll, KK1
Brehmer, B1
Marquardt, H1
Madsen, PO1
Kaul, P1
Prasad, GC1
Gupta, RC1
Udupa, KN1
Alfthan, OS1
Scott, WW1
Schirmer, HK1

Reviews

6 reviews available for estrone and Cancer of Prostate

ArticleYear
Urinary estrogen metabolites and prostate cancer: a case-control study and meta-analysis.
    Journal of experimental & clinical cancer research : CR, 2009, Oct-08, Volume: 28

    Topics: Aged; Case-Control Studies; Chromatography, Liquid; Estrogens; Humans; Hydroxyestrones; Male; Mass S

2009
[Estrogen-dependent neoplasia - what is the significance of estradiol metabolites].
    Zentralblatt fur Gynakologie, 2003, Volume: 125, Issue:11

    Topics: 2-Methoxyestradiol; Anticarcinogenic Agents; Breast Neoplasms; Estradiol; Estrogens, Catechol; Femal

2003
Control of prostate growth.
    Urology, 1981, Volume: 17, Issue:Suppl 3

    Topics: Adrenal Glands; Adult; Aged; Dihydrotestosterone; Estradiol; Estrone; Follicle Stimulating Hormone;

1981
Metabolic parameters of Estracyt pertinent to its effects in prostatic cancer.
    Urology, 1984, Volume: 23, Issue:6 Suppl

    Topics: Adenocarcinoma; Animals; Bile; Biotransformation; Estradiol; Estramustine; Estrone; Half-Life; Human

1984
Specific binding of estramustine to prostatic proteins.
    Urology, 1984, Volume: 23, Issue:6 Suppl

    Topics: Animals; Carrier Proteins; Cytosol; Epithelium; Estradiol; Estramustine; Estrone; Humans; Male; Nitr

1984
Clinical pharmacokinetics of estramustine phosphate.
    Urology, 1984, Volume: 23, Issue:6 Suppl

    Topics: Absorption; Dose-Response Relationship, Drug; Estradiol; Estramustine; Estrone; Feces; Half-Life; Hu

1984

Trials

4 trials available for estrone and Cancer of Prostate

ArticleYear
Soy protein isolate increases urinary estrogens and the ratio of 2:16alpha-hydroxyestrone in men at high risk of prostate cancer.
    The Journal of nutrition, 2007, Volume: 137, Issue:10

    Topics: Aged; Estrogens; Humans; Hydroxyestrones; Male; Middle Aged; Phytoestrogens; Prostatic Neoplasms; So

2007
Repeat polymorphisms in estrogen metabolism genes and prostate cancer risk: results from the Prostate Cancer Prevention Trial.
    Carcinogenesis, 2011, Volume: 32, Issue:10

    Topics: Aromatase; Case-Control Studies; Cholesterol Side-Chain Cleavage Enzyme; DNA; Estradiol; Estrogens;

2011
Testicular and adrenocortical function in men with prostatic cancer and in healthy age-matched controls.
    British journal of urology, 1997, Volume: 79, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Estrone; Gonadal Ste

1997
Impairment of estramustine phosphate absorption by concurrent intake of milk and food.
    European journal of clinical pharmacology, 1990, Volume: 38, Issue:2

    Topics: Aged; Animals; Biological Availability; Chromatography, Gas; Estramustine; Estrone; Food; Humans; Ma

1990

Other Studies

69 other studies available for estrone and Cancer of Prostate

ArticleYear
Urinary oestrogen steroidome as an indicator of the risk of localised prostate cancer progression.
    British journal of cancer, 2021, Volume: 125, Issue:1

    Topics: Aged; Disease Progression; Estradiol; Humans; Hydroxyestrones; Male; Mass Spectrometry; Middle Aged;

2021
Urinary estrogen metabolites and prostate cancer: a case-control study in the United States.
    Cancer causes & control : CCC, 2002, Volume: 13, Issue:10

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Case-Control Studies; Humans; Hydroxyestrones; Logistic Mod

2002
The effects of 2-substituted oestrogen sulphamates on the growth of prostate and ovarian cancer cells.
    The Journal of steroid biochemistry and molecular biology, 2003, Volume: 84, Issue:2-3

    Topics: 2-Methoxyestradiol; Apoptosis; Cell Division; Cell Separation; Estradiol; Estrone; Female; Flow Cyto

2003
Urinary estrogen metabolites, prostate specific antigen, and body mass index among African-American men in South Carolina.
    Cancer detection and prevention, 2005, Volume: 29, Issue:6

    Topics: Adult; Aged; Black or African American; Body Mass Index; Estrogens; Humans; Hydroxyestrones; Male; M

2005
Potential biomarker for early risk assessment of prostate cancer.
    The Prostate, 2006, Oct-01, Volume: 66, Issue:14

    Topics: Antibodies, Monoclonal; Biomarkers, Tumor; DNA Adducts; Early Diagnosis; Electrophoresis, Capillary;

2006
Extensive Alteration of Androgen Precursor Levels After Castration in Prostate Cancer Patients and Their Association With Active Androgen Level.
    The Journal of urology, 2022, Volume: 208, Issue:6

    Topics: Androgen Antagonists; Androgens; Androstenedione; Androsterone; Dehydroepiandrosterone; Dihydrotesto

2022
Sex steroid hormone metabolism in relation to risk of aggressive prostate cancer.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2014, Volume: 23, Issue:11

    Topics: Aged; Case-Control Studies; Estradiol; Estrogens; Estrone; Gonadal Steroid Hormones; Humans; Male; M

2014
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.
    Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19

    Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Discovery; Endometriosi

2015
Serum androgens and prostate cancer risk: results from the placebo arm of the Prostate Cancer Prevention Trial.
    Cancer causes & control : CCC, 2016, Volume: 27, Issue:2

    Topics: Aged; Androgens; Androstane-3,17-diol; Arm; Biopsy; Case-Control Studies; Estradiol; Estrone; Humans

2016
Sex hormones and the risk of incident prostate cancer.
    Urology, 2010, Volume: 76, Issue:5

    Topics: Aged; Case-Control Studies; Cohort Studies; Estradiol; Estrone; Gas Chromatography-Mass Spectrometry

2010
Editorial comment. Sex hormones and the risk of incident prostate cancer.
    Urology, 2010, Volume: 76, Issue:5

    Topics: Aged; Androgens; Estrogens; Estrone; Gonadal Steroid Hormones; Humans; Male; Prostatic Neoplasms; Ri

2010
Changes of androgen receptor and insulin-like growth factor-1 in LNCaP prostate cancer cells treated with sex hormones and flutamide.
    Asian Pacific journal of cancer prevention : APJCP, 2010, Volume: 11, Issue:6

    Topics: Androgen Antagonists; Androgens; Blotting, Western; Cell Line, Tumor; Dihydrotestosterone; Estrogens

2010
Serum estrogen levels and prostate cancer risk in the prostate cancer prevention trial: a nested case-control study.
    Cancer causes & control : CCC, 2011, Volume: 22, Issue:8

    Topics: 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Case-Control Studies; Estradiol; Estrone; Fem

2011
Expression changes and regulation of AR and IGF-1 in PC3 prostate cancer cells treated with sexual hormones and flutamide.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2012, Volume: 33, Issue:6

    Topics: Androgen Antagonists; Androgens; Blotting, Western; Dihydrotestosterone; Estrogens; Estrone; Flutami

2012
Inhibition of steryl sulfatase activity in LNCaP human prostate cancer cells.
    Steroids, 2002, Volume: 67, Issue:10

    Topics: Arylsulfatases; Breast Neoplasms; Danazol; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Estron

2002
[Hemorrhagic chromophobe adenoma of pituitary gland in a patient with cancer of prostate treated with folliculin].
    Rivista di anatomia patologica e di oncologia, 1954, Volume: 8, Issue:5

    Topics: Adenoma, Chromophobe; Estrogens; Estrone; Humans; Male; Neoplasms; Pituitary Gland; Pituitary Neopla

1954
PROSTATE CANCER IN THE RAT.
    National Cancer Institute monograph, 1963, Volume: 12

    Topics: Androgens; Estradiol Congeners; Estrogens; Estrone; Humans; Male; Mechlorethamine; Neoplasms; Neopla

1963
HORMONAL INFLUENCES ON THE NUCLEIC ACID METABOLISM OF THE HUMAN PROSTATE IN VITRO: A PILOT STUDY.
    Investigative urology, 1963, Volume: 1

    Topics: Carbon Isotopes; DNA; Estrone; Formates; Humans; In Vitro Techniques; Male; Metabolism; Pharmacology

1963
[STEROID HORMONE EXCRETION OF PATIENTS WITH DISEASES OF THE PROSTATE UNDER TREATMENT WITH NATURAL AND SYNTHETIC ESTROGENS].
    Acta endocrinologica, 1964, Volume: 45

    Topics: 17-Ketosteroids; Adenoma; Adrenal Cortex Hormones; Carcinoma; Estradiol; Estradiol Congeners; Estrio

1964
A STUDY OF STEROID EXCRETION IN PATIENTS WITH PROSTATIC CANCER.
    Investigative urology, 1964, Volume: 1

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Androsterone; Biopsy; Cortisone; Dehydroepiandrosterone; D

1964
HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL.
    Science (New York, N.Y.), 1964, Aug-14, Volume: 145, Issue:3633

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Aged; Androsterone; Breast Neoplasms; Creatine; Creatinine

1964
URINARY EXCRETION OF ESTRONE, ESTRADIOL AND ESTRIOL BY PATIENTS WITH PROSTATIC CANCER AND BENIGN PROSTATIC HYPERTROPHY.
    The Journal of urology, 1965, Volume: 93

    Topics: Androsterone; Estradiol; Estriol; Estrone; Humans; Male; Mice; Prostatic Hyperplasia; Prostatic Neop

1965
THE METABOLISM OF (14C)ESTRONE BY HYPERTROPHIC AND CARCINOMATOUS HUMAN PROSTATE TISSUE.
    Biochimica et biophysica acta, 1965, Mar-08, Volume: 97

    Topics: Chromatography; Diethylstilbestrol; Estradiol; Estrogens; Estrone; Humans; Hydroxysteroid Dehydrogen

1965
[Cancer of the prostate treated by folliculin; results after nine years].
    Journal belge d'urologie, 1950, Volume: 19, Issue:2

    Topics: Contraceptive Agents, Female; Estradiol Congeners; Estrogens; Estrone; Female; Humans; Male; Neoplas

1950
Steroid sulfatase and estrogen sulfotransferase in human prostate cancer.
    The Prostate, 2006, Jun-15, Volume: 66, Issue:9

    Topics: Cell Line, Tumor; Estradiol; Estrone; Humans; Immunohistochemistry; Male; Prostatic Neoplasms; Stery

2006
Estrone sulfate (E1S), a prognosis marker for tumor aggressiveness in prostate cancer (PCa).
    The Journal of steroid biochemistry and molecular biology, 2008, Volume: 109, Issue:1-2

    Topics: Adult; Aged; Androgens; Biomarkers, Tumor; Blood Chemical Analysis; Case-Control Studies; Estradiol;

2008
Methodologic basis for the radioimmunoassay of endogenous steroids in human prostatic tissue.
    Investigative urology, 1980, Volume: 17, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Dihydrotestosterone; Estradiol; Estrone; Humans; Male; Middle Aged; Pro

1980
Effect of diet on plasma and urinary hormones in South African black men with prostatic cancer.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Aged; Androgens; Androsterone; Black People; Dehydroepiandrosterone; Diet; Estriol; Estrogens; Estro

1982
Plasma steroids in benign prostatic hypertrophy and carcinoma of the prostate.
    Journal of steroid biochemistry, 1982, Volume: 17, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; Age Factors; Aged; Dihydrotestosterone; Estradiol; Estrone; Humans; Hy

1982
[Pharmacology and metabolism of a new therapeutic drug for prostatic cancer "Estracyt"].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents; Estramustine; Estrone; Follicle Stimulating Hormone; Humans; Luteini

1984
Hormone levels in prostatic fluid from healthy finns and prostate cancer patients.
    European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:10

    Topics: Body Fluids; Estradiol; Estrone; Hormones; Humans; Male; Prolactin; Prostate; Prostatic Neoplasms; T

1984
Prostate cancer; plasma concentrations of estramustine phosphate and its metabolites.
    New York state journal of medicine, 1980, Volume: 80, Issue:9

    Topics: Estradiol; Estramustine; Estrone; Humans; Male; Nitrogen Mustard Compounds; Prostatic Neoplasms

1980
Abnormal levels of plasma hormones in men with prostate cancer: evidence toward a "two-disease" theory.
    The Prostate, 1982, Volume: 3, Issue:6

    Topics: Age Factors; Aged; Dihydrotestosterone; Estrone; Hormones; Humans; Hydrocortisone; Male; Middle Aged

1982
Familial prostatic cancer risk and low testosterone.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:6

    Topics: Dihydrotestosterone; Estradiol; Estrone; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk; Sex H

1982
Blood hormone profiles in prostate cancer patients in high-risk and low-risk populations.
    Cancer, 1981, Nov-15, Volume: 48, Issue:10

    Topics: Acid Phosphatase; Age Factors; Aged; Black or African American; Black People; Estrone; Hormones; Hum

1981
Radioimmunoassay of tissue steroids in adenocarcinoma of the prostate.
    Cancer, 1981, Dec-01, Volume: 48, Issue:11

    Topics: Adenocarcinoma; Biopsy, Needle; Dihydrotestosterone; Estradiol; Estrone; Hormones; Humans; Male; Pro

1981
Plasma concentrations of estramustine phosphate and its major metabolites in patients with prostatic carcinoma treated with different doses of estramustine phosphate (Estracyt).
    Scandinavian journal of urology and nephrology, 1981, Volume: 15, Issue:3

    Topics: Administration, Oral; Aged; Carcinoma; Estradiol; Estramustine; Estrone; Humans; Male; Middle Aged;

1981
Metabolism of 3H-estradiol in men with prostate cancer.
    European journal of cancer, 1980, Volume: 16, Issue:2

    Topics: Aged; Estradiol; Estriol; Estrone; Humans; Male; Middle Aged; Prostatic Neoplasms

1980
Estrone and estradiol concentrations in the testis and spermatic and peripheral venous blood of elderly men: the influence of estrogen treatment.
    Journal of steroid biochemistry, 1980, Volume: 13, Issue:7

    Topics: Aged; Estradiol; Estrone; Humans; Male; Middle Aged; Organophosphorus Compounds; Prostatic Neoplasms

1980
Specificity of glucuronosyltransferase activity in the human cancer cell line LNCaP, evidence for the presence of at least two glucuronosyltransferase enzymes.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4

    Topics: Adenocarcinoma; Androstane-3,17-diol; Androsterone; Binding, Competitive; Dihydrotestosterone; Estra

1995
Inhibition of 17beta-hydroxysteroid oxidoreductase by flavonoids in breast and prostate cancer cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1998, Volume: 217, Issue:3

    Topics: 17-Hydroxysteroid Dehydrogenases; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrone; Female; F

1998
Differential uptake of estramustine phosphate metabolites and its correlation with the levels of estramustine binding protein in prostate tumor tissue.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:9

    Topics: Aged; Antineoplastic Agents, Hormonal; Carrier Proteins; Estradiol; Estramustine; Estrone; Humans; M

1998
Androgen antagonistic effect of estramustine phosphate (EMP) metabolites on wild-type and mutated androgen receptor.
    Biochemical pharmacology, 1998, May-01, Volume: 55, Issue:9

    Topics: Androgen Antagonists; Antineoplastic Agents, Alkylating; Binding, Competitive; Estramustine; Estroge

1998
Estrogens increase the endothelial nitric oxide synthase (ecNOS) mRNA level in LNCaP human prostate carcinoma cells.
    The Prostate, 2000, Nov-01, Volume: 45, Issue:3

    Topics: Endothelium; Estradiol; Estrone; Humans; Male; Nitric Oxide Synthase; Prostatic Neoplasms; RNA, Mess

2000
Structure-function aspects and inhibitor design of type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3).
    Molecular and cellular endocrinology, 2001, Jan-22, Volume: 171, Issue:1-2

    Topics: 17-Hydroxysteroid Dehydrogenases; 20-alpha-Dihydroprogesterone; 3-alpha-Hydroxysteroid Dehydrogenase

2001
Inhibitors of human and rat testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD) as potential agents for prostatic cancer.
    Journal of enzyme inhibition, 2001, Volume: 16, Issue:1

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Benzoquinones; Drug Evaluation, Preclini

2001
Regulation of cell-to-cell communication in non-tumorigenic and malignant human prostate epithelial cells.
    The Prostate, 2002, Feb-01, Volume: 50, Issue:2

    Topics: Cell Communication; Cell Transformation, Neoplastic; Colforsin; Connexins; Epithelial Cells; Estrone

2002
Estrogens affect endothelin-1 mRNA expression in LNCaP human prostate carcinoma cells.
    European urology, 2002, Volume: 41, Issue:5

    Topics: Biomarkers, Tumor; Endothelin-1; Estradiol; Estrogen Receptor beta; Estrone; Gene Expression; Humans

2002
[Tissue culture of the human prostate--effects of sex hormones on subcultures of cells from benign prostatic hyperplasia and carcinoma of the prostate (author's transl)].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1978, Volume: 69, Issue:3

    Topics: Adenocarcinoma; Cell Count; Cell Division; Culture Techniques; Diethylstilbestrol; Dihydrotestostero

1978
Tumour markers in urology: aids in cancer diagnosis and management.
    Urological research, 1979, Jun-22, Volume: 7, Issue:2

    Topics: Acid Phosphatase; Alkaline Phosphatase; alpha 1-Antitrypsin; alpha-Fetoproteins; Antibodies, Neoplas

1979
Conversion of androstenedione to estrone in human fibroblasts cultured from prostate, genital and nongenital skin.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1979, Volume: 11, Issue:11

    Topics: Adolescent; Adult; Aged; Androstenedione; Cells, Cultured; Estrone; Fibroblasts; Humans; Kinetics; M

1979
Percutaneous 17 beta-estradiol in treatment of cancer of prostate.
    Urology, 1979, Volume: 14, Issue:4

    Topics: Adenocarcinoma; Dihydrotestosterone; Estradiol; Estrone; Follicle Stimulating Hormone; Humans; Lipop

1979
The development of prostatic adenocarcinoma in Nb rats following prolonged sex hormone administration.
    Cancer research, 1977, Volume: 37, Issue:6

    Topics: Adenocarcinoma; Animals; Drug Synergism; Estrone; Male; Neoplasms, Experimental; Prostatic Neoplasms

1977
Sex steroids as a cause of adenocarcinoma of the dorsal prostate in Nb rats, and their influence on the growth of transplants.
    Oncology, 1977, Volume: 34, Issue:3

    Topics: Adenocarcinoma; Androgens; Animals; Estrogens; Estrone; Male; Neoplasm Transplantation; Neoplasms, E

1977
Intratesticular site of aromatization in the human.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 42, Issue:6

    Topics: Adult; Aged; Androstenedione; Estradiol; Estrone; Humans; Infant; Male; Middle Aged; Prostatic Neopl

1976
Prostatic cancer and SCH-13521: II. Histological alterations and the pituitary gonadal axis.
    The Journal of urology, 1975, Volume: 113, Issue:6

    Topics: Aged; Anilides; Biopsy, Needle; Cerebrovascular Disorders; Estradiol; Estrone; Flutamide; Follicle S

1975
Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells.
    Cancer research, 1991, Oct-01, Volume: 51, Issue:19

    Topics: Androgens; Androstane-3,17-diol; Binding, Competitive; Cell Cycle; Dihydrotestosterone; Dose-Respons

1991
Dietary and hormonal evaluation of men at different risks for prostate cancer: plasma and fecal hormone-nutrient interrelationships.
    The American journal of clinical nutrition, 1990, Volume: 51, Issue:3

    Topics: Adult; Aged; Christianity; Diet; Dietary Fiber; Energy Metabolism; Estradiol; Estrone; Fatty Acids;

1990
A prospective, population-based study of androstenedione, estrogens, and prostatic cancer.
    Cancer research, 1990, Jan-01, Volume: 50, Issue:1

    Topics: Adult; Aged; Androstenedione; California; Cohort Studies; Estradiol; Estrone; Humans; Male; Middle A

1990
Urinary oestrogen excretion in benign prostatic hyperplasia and prostatic cancer.
    British journal of urology, 1989, Volume: 64, Issue:2

    Topics: Aged; Aged, 80 and over; Estradiol; Estriol; Estrogens; Estrone; Humans; Male; Middle Aged; Prostati

1989
Differential metabolism of dehydroepiandrosterone sulfate and estrogen conjugates by normal or malignant AXC/SSh rat prostate cells and effects of these steroid conjugates on cancer cell proliferation in vitro.
    Journal of steroid biochemistry, 1988, Volume: 29, Issue:6

    Topics: Animals; Cell Division; Cell Line; Clone Cells; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfa

1988
Uptake of estramustine phosphate (estracyt) metabolites in prostatic cancer.
    The Journal of urology, 1988, Volume: 140, Issue:5

    Topics: Aged; Carcinoma; Carrier Proteins; Estradiol; Estramustine; Estrone; Humans; Male; Middle Aged; Nitr

1988
Dietary fat in relation to hormonal induction of mammary and prostatic carcinoma in Nb rats.
    Carcinogenesis, 1987, Volume: 8, Issue:6

    Topics: Animals; Dietary Fats; Estrone; Female; Kinetics; Male; Mammary Neoplasms, Experimental; Prostatic N

1987
Growth and hormonal response of cells derived from carcinoma and hyperplasia of the prostate in monolayer cell culture. A possible in vitro model for clinical chemotherapy.
    The Journal of urology, 1972, Volume: 108, Issue:6

    Topics: Adenocarcinoma; Androsterone; Carcinoma; Cell Division; Cells, Cultured; Diethylstilbestrol; Estrone

1972
Urinary hormone metabolites in cancer and benign hyperplasia of the prostate: a multivariate statistical analysis.
    Annals of the New York Academy of Sciences, 1966, Jan-21, Volume: 125, Issue:3

    Topics: 17-Ketosteroids; Adenocarcinoma; Adrenal Cortex Hormones; Estriol; Estrone; Hormones; Humans; Male;

1966
A comparative study of urinary oestrogens in the cancer of breast and prostate.
    Indian journal of cancer, 1974, Volume: 11, Issue:2

    Topics: Adult; Aged; Breast Neoplasms; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Male; Middle

1974
Oestradiol production rates in man before and after orchiectomy for cancer.
    The Journal of endocrinology, 1970, Volume: 46, Issue:1

    Topics: Aged; Breast Neoplasms; Castration; Estradiol; Estriol; Estrone; Humans; Male; Middle Aged; Prostati

1970
The inhibiting effect of irradiation on gynecomastia induced by estrogen hormone stimulation: an experimental study.
    The Journal of urology, 1969, Volume: 101, Issue:6

    Topics: Animals; Castration; Estrogens; Estrone; Gynecomastia; Male; Mammary Glands, Animal; Prostatic Neopl

1969
A new oral progestational steroid effective in treating prostatic cancer.
    Transactions of the American Association of Genito-Urinary Surgeons, 1966, Volume: 58

    Topics: Acid Phosphatase; Aged; Animals; Biological Assay; Castration; Dogs; Estradiol; Estrone; Humans; Liv

1966