estrone has been researched along with Bonnevie-Ullrich Syndrome in 22 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
Bonnevie-Ullrich Syndrome: This syndrome that was originally observed by Ullrich, and designated as identical to TURNER SYNDROME, related the webbing of the neck, loose skin and other anomalies of the syndrome to accumulation of fluid in the embryo starting at the head and dispersing to the extremities (as observed by Bonnevie in mice). Commonly observed at birth in Turner Syndrome and NOONAN SYNDROME; EDEMA of the extremities usually recedes by one year and is an early sign of Turner syndrome, especially in female neonates.
Excerpt | Relevance | Reference |
---|---|---|
"Our objective was to assess metabolic effects of oral vs transdermal (TD) 17β-E₂ replacement using estrogen concentration-based dosing in girls with Turner syndrome (TS)." | 2.78 | Metabolic effects of oral versus transdermal 17β-estradiol (E₂): a randomized clinical trial in girls with Turner syndrome. ( Hossain, J; Klein, KO; Mauras, N; Mericq, V; Ross, JL; Santen, RJ; Singh, R; Taboada, M; Torres-Santiago, L; Unanue, N, 2013) |
"Estrone was detected in cerebrospinal fluid before and after but not during dexamethasone treatment." | 1.26 | Pseudotumor cerebri in an obese woman with Turner syndrome. ( Binstock, ML; Donaldson, JO, 1981) |
"To evaluate the relationship between the secretion of gonadotropins and adrenal androgens, patients with gonadal agenesis were evaluated by (a) administering human luteinizing hormone (hLH) for 5 days with or without estrogen pretreatment to agonadal patients who had prepubertal LH levels; (b) correlating circulating gonadotropin levels with adrenal androgens in 45 patients; and (c) comparing adrenal androgens with gonadotropins after long-term administration of estrogen or androgens." | 1.25 | Lack of correlation between gonadotropin and adrenal androgen levels in agonadal children. ( Blizzard, RM; Kowarski, A; Lee, PA; Migeon, CJ, 1975) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 19 (86.36) | 18.7374 |
1990's | 1 (4.55) | 18.2507 |
2000's | 1 (4.55) | 29.6817 |
2010's | 1 (4.55) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Torres-Santiago, L | 1 |
Mericq, V | 1 |
Taboada, M | 1 |
Unanue, N | 1 |
Klein, KO | 1 |
Singh, R | 1 |
Hossain, J | 1 |
Santen, RJ | 1 |
Ross, JL | 1 |
Mauras, N | 1 |
Bannink, EM | 1 |
van Sassen, C | 1 |
van Buuren, S | 1 |
de Jong, FH | 1 |
Lequin, M | 1 |
Mulder, PG | 1 |
de Muinck Keizer-Schrama, SM | 1 |
KELLY, LW | 1 |
Reiter, EO | 1 |
Duckett, GE | 1 |
Root, AW | 1 |
Donaldson, JO | 2 |
Horak, E | 1 |
Binstock, ML | 1 |
Lee, PA | 1 |
Kowarski, A | 1 |
Migeon, CJ | 1 |
Blizzard, RM | 1 |
Isaacs, AJ | 1 |
Havard, CW | 1 |
Nagamani, M | 1 |
Lin, TJ | 1 |
McDonough, PG | 1 |
Watatani, H | 1 |
McPherson, JC | 1 |
Mahesh, VB | 1 |
Conte, FA | 2 |
Grumbach, MM | 2 |
Kaplan, SL | 2 |
Toublanc, JE | 2 |
Grenier, J | 1 |
Nahoul, K | 1 |
Scholler, R | 2 |
Canlorbe, P | 2 |
Illig, R | 1 |
DeCampo, C | 1 |
Lang-Muritano, MR | 1 |
Prader, A | 1 |
Torresani, T | 1 |
Werder, EA | 1 |
Willi, U | 1 |
Schenkel, L | 1 |
Stone, D | 1 |
Mackay, AM | 1 |
Pettigrew, N | 1 |
Symington, T | 1 |
Neville, AM | 1 |
Howard, RP | 1 |
Keaty, EC | 1 |
Job, JC | 1 |
Garnier, PE | 1 |
Chaussain, JL | 1 |
Kelch, RP | 1 |
Rosenfield, RL | 1 |
Fang, VS | 1 |
Dupon, C | 2 |
Kim, MH | 2 |
Refetoff, S | 1 |
Bidlingmaier, F | 1 |
Wagner-Barnack, M | 1 |
Butenandt, O | 1 |
Knorr, D | 1 |
Hosseinian, AH | 1 |
Sacris, MO | 1 |
Cleary, RE | 1 |
Nankin, HR | 1 |
Loiudice, T | 1 |
Loraine, JA | 1 |
Adamopoulos, DA | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Estrogen Dosing in Turner Syndrome:Pharmacology & Metabolism[NCT00837616] | Phase 4 | 41 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
(NCT00837616)
Timeframe: 12 months
Intervention | kg/m2 (Mean) |
---|---|
Oral Estradiol | 0.075 |
Transdermal Estradiol | 0.65 |
(NCT00837616)
Timeframe: 12 months
Intervention | kg (Mean) |
---|---|
Oral Estradiol | 1.03 |
Transdermal Estradiol | 1.67 |
(NCT00837616)
Timeframe: 12 months
Intervention | percent fat mass (Mean) |
---|---|
Oral Estradiol | -0.14 |
Transdermal Estradiol | -0.64 |
(NCT00837616)
Timeframe: 12 months
Intervention | kilograms (Mean) |
---|---|
Oral Estradiol | 1.1 |
Transdermal Estradiol | 1.9 |
(NCT00837616)
Timeframe: 12 months
Intervention | ng/ml (Mean) |
---|---|
Oral Estradiol | -16 |
Transdermal Estradiol | 28 |
(NCT00837616)
Timeframe: 12 months
Intervention | Kcal/Fat Free Mass/day (Mean) |
---|---|
Oral Estradiol | 10 |
Transdermal Estradiol | 7.3 |
(NCT00837616)
Timeframe: 12 months
Intervention | pg/ml (Mean) |
---|---|
Oral Estradiol | 124 |
Transdermal Estradiol | 74 |
(NCT00837616)
Timeframe: 12 months
Intervention | pg/mL (Mean) |
---|---|
Oral Estradiol | 504 |
Transdermal Estradiol | 43 |
(NCT00837616)
Timeframe: 12 months
Intervention | pg/mL (Mean) |
---|---|
Oral Estradiol | 63638 |
Transdermal Estradiol | 1875 |
(NCT00837616)
Timeframe: 12 months
Intervention | mg/dl (Mean) | |||
---|---|---|---|---|
Total Cholesterol | Low Density Lipoprotein | High Density Lipoprotein | Triglycerides | |
Oral Estradiol | 168 | 93 | 56 | 95 |
Transdermal Estradiol | 153 | 88 | 50 | 70 |
1 review available for estrone and Bonnevie-Ullrich Syndrome
Article | Year |
---|---|
Chromosomal mosaicism in the human and chromosomal change in vitro.
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosomes; Chromosomes, Human, 13-15; Chromosomes, H | 1966 |
2 trials available for estrone and Bonnevie-Ullrich Syndrome
Article | Year |
---|---|
Metabolic effects of oral versus transdermal 17β-estradiol (E₂): a randomized clinical trial in girls with Turner syndrome.
Topics: Administration, Oral; Adolescent; Adult; Basal Metabolism; Biotransformation; Body Composition; Bone | 2013 |
Puberty induction in Turner syndrome: results of oestrogen treatment on development of secondary sexual characteristics, uterine dimensions and serum hormone levels.
Topics: Administration, Oral; Adolescent; Breast; Child; Cross-Sectional Studies; Dose-Response Relationship | 2009 |
19 other studies available for estrone and Bonnevie-Ullrich Syndrome
Article | Year |
---|---|
Ovarian dwarfism with pituitary tumor.
Topics: Dwarfism; Estrone; Humans; Hypogonadism; Norethynodrel; Pituitary Neoplasms; Turner Syndrome | 1963 |
Responses to constant infusion of LH-RH in girls with primary hypogonadism.
Topics: Adolescent; Adult; Androstenedione; Child; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; E | 1980 |
Cerebrospinal fluid oestrone in pseudotumour cerebri.
Topics: Adult; Cerebrospinal Fluid Proteins; Dexamethasone; Diet, Reducing; Estradiol; Estriol; Estrone; Fem | 1982 |
Pseudotumor cerebri in an obese woman with Turner syndrome.
Topics: Adrenal Cortex Hormones; Adult; Androstenedione; Estrogens; Estrone; Female; Humans; Menstruation; O | 1981 |
Lack of correlation between gonadotropin and adrenal androgen levels in agonadal children.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Androgens; Dehydroepiandrosterone; Estrogens, Conjugated ( | 1975 |
Effect of piperazine oestrone sulphate on serum lipids and lipoproteins in menopausal women.
Topics: Cholesterol; Climacteric; Estrone; Fatty Acids; Fatty Acids, Nonesterified; Female; Humans; Lipids; | 1977 |
Clinical and endocrine studies in menopausal women after estradiol pellet implantation.
Topics: Adult; Depression, Chemical; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Humans; Lutei | 1977 |
A diphasic pattern of gonadotropin secretion in patients with the syndrome of gonadal dysgenesis.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Estradiol; Estrone; Female; Follicle Stimul | 1975 |
[Levels of estrone, estradiol 17 beta and testosterone in girls during normal puberty. Applications in pathology].
Topics: Adolescent; Adult; Child; Child, Preschool; Estradiol; Estrone; Female; Humans; Hypopituitarism; Inf | 1975 |
A physiological mode of puberty induction in hypogonadal girls by low dose transdermal 17 beta-oestradiol.
Topics: Administration, Cutaneous; Adolescent; Child; Estradiol; Estrone; Female; Follicle Stimulating Hormo | 1990 |
Tumors of dysgenetic gonads (gonadoblastoma): ultrastructural and steroidogenic aspects.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Androstenes; Basement Membrane; Cell Nucleus; Cytopla | 1974 |
Evaluation of equilin 3-monosulfate and other estrogens. Comparison by study of urinary gonadotropins in women.
Topics: 17-Ketosteroids; Administration, Oral; Adult; Aged; Amenorrhea; Animals; Biological Assay; Castratio | 1971 |
Effect of synthetic luteinizing hormone-releasing hormone (LH-RH) on the release of gonadotropins in hypophyso-gonadal disorders of children and adolescents. V. Agonadism.
Topics: Adolescent; Child; Child, Preschool; Disorders of Sex Development; Estradiol; Estrone; Female; Folli | 1974 |
Episodic secretion of luteinizing hormone (LH) in adolescent patients with the syndrome of gonadal dysgenesis.
Topics: Adolescent; Adult; Child; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Humans; Iodine I | 1973 |
The effects of low doses of depot estradiol and testosterone in teenagers with ovarian failure and Turner's syndrome.
Topics: Adolescent; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Half-Life; Humans; Luteinizing | 1973 |
Plasma estrogens in childhood and puberty under physiologic and pathologic conditions.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adult; Animals; Cattle; C | 1973 |
Hormonal profile in patients with gonadal dysgenesis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Androstenedione; Chorionic Gonadotropin; Depression, Che | 1974 |
Primary amenorrhea in a 46,XX-46,XXq-female.
Topics: Adult; Amenorrhea; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Humans; Karyotyping; Lu | 1974 |
Recent studies on the estimation of human pituitary gonadotrophins in urine in clinical conditions.
Topics: Adult; Aged; Animals; Ascorbic Acid; Climacteric; Clomiphene; Contraceptives, Oral; Estradiol; Estri | 1970 |