Page last updated: 2024-11-07

estrone and Bone Loss, Osteoclastic

estrone has been researched along with Bone Loss, Osteoclastic in 19 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Research Excerpts

ExcerptRelevanceReference
" Serum sex hormone binding globulin increased and leptin decreased with weight loss (P < 0."5.09Moderate energy restriction increases bone resorption in obese postmenopausal women. ( Chowdhury, HA; Heymsfield, SB; Pierson, RN; Ricci, TA; Shapses, SA; Stahl, T, 2001)
"Letrozole treatment reduced serum estrone (E1) and estradiol (E2) to near undetectable levels (p < 0."2.70Role of low levels of endogenous estrogen in regulation of bone resorption in late postmenopausal women. ( Heshmati, HM; Khosla, S; Melton, LJ; O'Fallon, WM; Riggs, BL; Robins, SP, 2002)
"Measurements of a bone resorption marker, i."2.69Estrogen activity and novel tissue selectivity of delta8,9-dehydroestrone sulfate in postmenopausal women. ( Baracat, E; Dey, M; Haidar, M; Lopez, FJ; Negro-Vilar, A; Pickar, J, 1999)
"Biochemical parameters reflecting bone resorption [urinary calcium/creatinine (Ca/Cr) and hydroxyproline/creatinine (OH/Cr)] were related to serum estrogens [estrone (E1) and estradiol (E2)] in 262 healthy women including 158 patients receiving estrogen replacement therapy (ERT) for at least 6 months, 49 eugonadal women, and 55 untreated postmenopausal women."2.67Minimal levels of serum estradiol prevent postmenopausal bone loss. ( Albert, A; Deroisy, R; Franchimont, P; Gaspard, U; Reginster, JY; Sarlet, N, 1992)
" The results showed reduced levels of both estrogens in smokers as compared with nonsmokers in all three dosage groups."2.66Cigarette smoking, serum estrogens, and bone loss during hormone-replacement therapy early after menopause. ( Christiansen, C; Jensen, J; Rødbro, P, 1985)
"Women in Group II (N = 37) with osteopenia had lower levels of E1G (P<0."1.34Age-related changes in bone turnover markers and ovarian hormones in premenopausal and postmenopausal Indian women. ( Bhanuprakash, KV; Desai, MP; Donde, UM; Khatkhatay, MI, 2007)
"60% of our patients showed increased bone resorption (PCA less than 55%); in these subjects testosterone and androstenedione plasma levels were significantly lower than in subjects not affected by osteoporosis."1.27Osteoporosis and decline of gonadal function in the elderly male. ( Foresta, C; Gribaldo, R; Guarneri, G; Mastrogiacomo, I; Meneghello, A; Mioni, R; Ruzza, G, 1984)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19906 (31.58)18.7374
1990's3 (15.79)18.2507
2000's10 (52.63)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
West, SL1
Scheid, JL1
De Souza, MJ1
Li, QN1
Hu, B1
Huang, LF1
Chen, Y1
Weng, LL1
Zheng, H1
Chen, HQ1
Riggs, BL2
Khosla, S3
Atkinson, EJ2
Dunstan, CR1
Melton, LJ3
Nozaki, M1
Hashimoto, K1
Nakano, H1
Desai, MP1
Bhanuprakash, KV1
Khatkhatay, MI1
Donde, UM1
Foresta, C1
Ruzza, G1
Mioni, R1
Guarneri, G1
Gribaldo, R1
Meneghello, A1
Mastrogiacomo, I1
Scarpellini, F1
Scarpellini, L1
Andreassi, S1
Cosmi, EV1
Baracat, E1
Haidar, M1
Lopez, FJ1
Pickar, J1
Dey, M1
Negro-Vilar, A1
Ricci, TA2
Heymsfield, SB2
Pierson, RN2
Stahl, T2
Chowdhury, HA1
Shapses, SA2
Von Thun, NL1
Ospina, M1
O'Fallon, WM2
Chapurlat, RD1
Bauer, DC1
Cummings, SR1
Heshmati, HM1
Robins, SP1
Reginster, JY1
Sarlet, N1
Deroisy, R1
Albert, A1
Gaspard, U1
Franchimont, P1
Selby, P1
McGarrigle, HH1
Peacock, M3
Riis, BJ1
Rødbro, P2
Christiansen, C2
Jensen, J1
Atkins, D2
Zanelli, JM1
Nordin, BE1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism[NCT03490513]Phase 4120 participants (Anticipated)Interventional2018-04-15Recruiting
Aromatase Inhibitors: Skeletal Effects and the Role of CYP19 Gene Polymorphisms[NCT00603967]151 participants (Actual)Interventional2006-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

7 trials available for estrone and Bone Loss, Osteoclastic

ArticleYear
Doxycycline may inhibit postmenopausal bone damage. Preliminary observations.
    Annals of the New York Academy of Sciences, 1994, Sep-06, Volume: 732

    Topics: Alkaline Phosphatase; Biomarkers; Bone Resorption; Doxycycline; Estradiol; Estrone; Female; Fibronec

1994
Estrogen activity and novel tissue selectivity of delta8,9-dehydroestrone sulfate in postmenopausal women.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:6

    Topics: Adult; Bone Resorption; Estrogens; Estrone; Female; Hot Flashes; Humans; Middle Aged; Pilot Projects

1999
Moderate energy restriction increases bone resorption in obese postmenopausal women.
    The American journal of clinical nutrition, 2001, Volume: 73, Issue:2

    Topics: Absorptiometry, Photon; Adipose Tissue; Body Composition; Bone Density; Bone Resorption; Diet, Reduc

2001
Bone turnover and density in obese premenopausal women during moderate weight loss and calcium supplementation.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2001, Volume: 16, Issue:7

    Topics: Absorptiometry, Photon; Adult; Amino Acids; Body Mass Index; Bone Density; Bone Resorption; Calcium,

2001
Role of low levels of endogenous estrogen in regulation of bone resorption in late postmenopausal women.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2002, Volume: 17, Issue:1

    Topics: Aged; Aromatase Inhibitors; Bone Remodeling; Bone Resorption; Double-Blind Method; Enzyme Inhibitors

2002
Minimal levels of serum estradiol prevent postmenopausal bone loss.
    Calcified tissue international, 1992, Volume: 51, Issue:5

    Topics: Analysis of Variance; Bone Resorption; Calcium; Creatinine; Estradiol; Estrogen Replacement Therapy;

1992
Cigarette smoking, serum estrogens, and bone loss during hormone-replacement therapy early after menopause.
    The New England journal of medicine, 1985, Oct-17, Volume: 313, Issue:16

    Topics: Adult; Bone Resorption; Drug Combinations; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; M

1985

Other Studies

12 other studies available for estrone and Bone Loss, Osteoclastic

ArticleYear
The effect of exercise and estrogen on osteoprotegerin in premenopausal women.
    Bone, 2009, Volume: 44, Issue:1

    Topics: Adolescent; Adult; Bone Density; Bone Resorption; Cross-Sectional Studies; Demography; Estrogens; Es

2009
Effects of low doses of hydrochloride tetracycline on bone metabolism and uterus in ovariectomized rats.
    Acta pharmacologica Sinica, 2003, Volume: 24, Issue:6

    Topics: Animals; Bone Resorption; Estrone; Female; Organ Size; Ovariectomy; Protein Synthesis Inhibitors; Ra

2003
Evidence that type I osteoporosis results from enhanced responsiveness of bone to estrogen deficiency.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2003, Volume: 14, Issue:9

    Topics: Aged; Bone Resorption; Estradiol; Estrone; Female; Glycoproteins; Gonadal Steroid Hormones; Humans;

2003
Relationship between bone resorption and adrenal sex steroids and their derivatives in oophorectomized women.
    Fertility and sterility, 2004, Volume: 82, Issue:6

    Topics: Adult; Amino Acids; Androstenedione; Bone Resorption; Creatinine; Cross-Sectional Studies; Dehydroep

2004
Age-related changes in bone turnover markers and ovarian hormones in premenopausal and postmenopausal Indian women.
    Journal of clinical laboratory analysis, 2007, Volume: 21, Issue:2

    Topics: Adult; Aged; Aging; Biomarkers; Body Mass Index; Bone and Bones; Bone Density; Bone Diseases, Metabo

2007
Osteoporosis and decline of gonadal function in the elderly male.
    Hormone research, 1984, Volume: 19, Issue:1

    Topics: Aged; Androstenedione; Bone Resorption; Estradiol; Estrone; Humans; Male; Middle Aged; Osteoporosis;

1984
Relationship of serum sex steroid levels to longitudinal changes in bone density in young versus elderly men.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aging; Body Mass Index; Bone Density; Bone Resorption; Estradiol; Es

2001
Association between endogenous hormones and sex hormone-binding globulin and bone turnover in older women: study of osteoporotic fractures.
    Bone, 2001, Volume: 29, Issue:4

    Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Biomarkers; Bone Resorption; Collagen; Collagen Type

2001
Comparison of the effects of oral and transdermal oestradiol administration on oestrogen metabolism, protein synthesis, gonadotrophin release, bone turnover and climacteric symptoms in postmenopausal women.
    Clinical endocrinology, 1989, Volume: 30, Issue:3

    Topics: Administration, Oral; Bone Resorption; Climacteric; Dose-Response Relationship, Drug; Estradiol; Est

1989
The role of serum concentrations of sex steroids and bone turnover in the development and occurrence of postmenopausal osteoporosis.
    Calcified tissue international, 1986, Volume: 38, Issue:6

    Topics: Aged; Androstenedione; Bone and Bones; Bone Resorption; Estradiol; Estrogens; Estrone; Female; Human

1986
The effect of oestrogens on parathyroid hormone mediated bone resorption in tissue culture.
    The Journal of endocrinology, 1972, Volume: 55, Issue:2

    Topics: Animals; Bone Resorption; Calcium; Citrates; Culture Techniques; Estradiol; Estriol; Estrogens; Estr

1972
The effect of oestrogens on the response of bone to parathyroid hormone in vitro.
    The Journal of endocrinology, 1972, Volume: 54, Issue:1

    Topics: Animals; Bone and Bones; Bone Resorption; Calcium; Citrates; Estradiol; Estriol; Estrogens; Estrone;

1972