Page last updated: 2024-11-07

estrone and Atypical Endometrial Hyperplasia

estrone has been researched along with Atypical Endometrial Hyperplasia in 28 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Atypical Endometrial Hyperplasia: A benign form of endometrial hyperplasia with increased number of cells with atypia. The atypical cells are large and irregular and have an increased nuclear/cytoplasmic ratio. The risk of progression to endometrial carcinoma rises with the increasing degree of cell atypia.

Research Excerpts

ExcerptRelevanceReference
"A regime of cyproterone acetate (CPA) (300 mg/day by the oral route for 30 days) has been used in 10 post-menopausal women with endometrial hyperplasia (8 atypical and 2 adenomatous)."7.67Treatment of endometrial hyperplasia with cyproterone acetate histological and hormonal aspects. ( Bulletti, C; Ciotti, P; Flamigni, C; Franceschetti, F; Jasonni, VM; Marabini, A; Naldi, S; Vignudelli, A, 1986)
"Plasma androstenedione (A) levels and plasma oestrone (E1) levels were measured by radioimmunoassay in a total of 135 healthy women (the control group), around the menopause."7.66Plasma androstenedione and oestrone levels before and after the menopause. I. Glandular hyperplasia and adenocarcinoma of the endometrium. ( Battaglia, F; Mango, D; Montemurro, A; Scirpa, P; Scirpa, S, 1982)
" Ten patients with histologically proven endometrial hyperplasia were treated with Danazol at a dosage of 600 mg/day for 30 days."5.27Preliminary report on postmenopausal endometrial hyperplasia treatment with Danazol: histological and endocrinological aspects. ( Bulletti, C; Ciotti, P; Flamigni, C; Jasonni, VM; La Marca, L; Naldi, S; Vignudelli, A, 1986)
"A regime of cyproterone acetate (CPA) (300 mg/day by the oral route for 30 days) has been used in 10 post-menopausal women with endometrial hyperplasia (8 atypical and 2 adenomatous)."3.67Treatment of endometrial hyperplasia with cyproterone acetate histological and hormonal aspects. ( Bulletti, C; Ciotti, P; Flamigni, C; Franceschetti, F; Jasonni, VM; Marabini, A; Naldi, S; Vignudelli, A, 1986)
"Plasma androstenedione (A) levels and plasma oestrone (E1) levels were measured by radioimmunoassay in a total of 135 healthy women (the control group), around the menopause."3.66Plasma androstenedione and oestrone levels before and after the menopause. I. Glandular hyperplasia and adenocarcinoma of the endometrium. ( Battaglia, F; Mango, D; Montemurro, A; Scirpa, P; Scirpa, S, 1982)
" Ten patients with histologically proven endometrial hyperplasia were treated with Danazol at a dosage of 600 mg/day for 30 days."1.27Preliminary report on postmenopausal endometrial hyperplasia treatment with Danazol: histological and endocrinological aspects. ( Bulletti, C; Ciotti, P; Flamigni, C; Jasonni, VM; La Marca, L; Naldi, S; Vignudelli, A, 1986)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199022 (78.57)18.7374
1990's2 (7.14)18.2507
2000's3 (10.71)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lobo, RA1
Liu, J1
Stanczyk, FZ1
Constantine, GD1
Pickar, JH2
Shadiack, AM1
Bernick, B1
Mirkin, S1
Bochkareva, NV1
Kolomiets, LA1
Kondakova, IV1
Stukanov, SL1
Tropina, TV1
Muntian, AB1
POLISHUK, WZ1
PLUNKETT, ER1
KASE, N1
Deng, L1
Broaddus, RR1
McCampbell, A1
Shipley, GL1
Loose, DS1
Stancel, GM1
Davies, PJ1
Goldzieher, JW1
Fariss, B1
Prost, O1
Adessi, GL1
Pelusi, G1
Moretti, B1
Martinelli, G1
Camerini, T1
Busacchi, P1
Cavallina, R1
Kasai, T1
Takeda, B1
Takamizawa, H1
Scirpa, P1
Mango, D1
Battaglia, F1
Scirpa, S1
Montemurro, A1
Forney, JP1
Milewich, L1
Chen, GT1
Garlock, JL1
Schwarz, BE1
Edman, CD2
MacDonald, PC2
James, VH2
Reed, MJ2
Folkerd, EJ1
Klemi, PJ1
Grönroos, M1
Rauramo, L1
Punnonen, R1
Niwa, K1
Murase, T1
Furui, T1
Morishita, S1
Mori, H2
Tanaka, T1
Tamaya, T1
Rebar, RW1
Trabal, J1
Mortola, J1
Whitehead, MI2
Badawy, SZ1
Elliott, LJ1
Elbadawi, A1
Marshall, LD1
Grodin, JM1
Vellios, F1
Siiteri, PK1
Brush, MG1
Milton, PJ1
Swain, M1
Moore, J1
Harris, ST1
Genant, HK1
Baylink, DJ1
Gallagher, JC1
Karp, SK1
McConnell, MA1
Green, EM1
Stoll, RW1
Jasonni, VM3
Franceschetti, F1
Ciotti, P3
Bulletti, C3
Vignudelli, A2
Marabini, A1
Naldi, S2
Flamigni, C3
Tabanelli, S1
Cappuccini, F1
Borini, A1
La Marca, L1
Beranek, PA1
Ghilchik, MW1
Rader, MD1
Flickinger, GL1
DeVilla, GO1
Mikuta, JJ1
Mikhail, G1
Markovski, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Aromatase Inhibitors: Skeletal Effects and the Role of CYP19 Gene Polymorphisms[NCT00603967]151 participants (Actual)Interventional2006-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for estrone and Atypical Endometrial Hyperplasia

ArticleYear
Estradiol and progesterone bioavailability for moderate to severe vasomotor symptom treatment and endometrial protection with the continuous-combined regimen of TX-001HR (oral estradiol and progesterone capsules).
    Menopause (New York, N.Y.), 2019, Volume: 26, Issue:7

    Topics: Adult; Aged; Biological Availability; Endometrial Hyperplasia; Estradiol; Estrone; Female; Hot Flash

2019
Identification of a novel estrogen-regulated gene, EIG121, induced by hormone replacement therapy and differentially expressed in type I and type II endometrial cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Dec-01, Volume: 11, Issue:23

    Topics: Adenocarcinoma; Biomarkers, Tumor; Case-Control Studies; Endometrial Hyperplasia; Endometrial Neopla

2005
Low-dose esterified estrogens (0.3 mg/day): long-term and short-term effects on menopausal symptoms and quality of life in postmenopausal women.
    Climacteric : the journal of the International Menopause Society, 2000, Volume: 3, Issue:3

    Topics: Double-Blind Method; Endometrial Hyperplasia; Equilin; Estrogen Replacement Therapy; Estrone; Female

2000
The effects of estrone (Ogen) on spinal bone density of postmenopausal women.
    Archives of internal medicine, 1991, Volume: 151, Issue:10

    Topics: Bone Density; Dose-Response Relationship, Drug; Double-Blind Method; Endometrial Hyperplasia; Estron

1991

Other Studies

24 other studies available for estrone and Atypical Endometrial Hyperplasia

ArticleYear
[Sex hormones in the systemic and local circulation in endometrial hyperplasia and neoplasia: correlation with the activity of estrogen-metabolizing enzymes].
    Voprosy onkologii, 2008, Volume: 54, Issue:6

    Topics: Androstenedione; Aromatase; Endometrial Hyperplasia; Endometrial Neoplasms; Estradiol; Estrone; Fema

2008
A case of pyometra due to prolonged oestrone administration.
    The Journal of obstetrics and gynaecology of the British Empire, 1963, Volume: 70

    Topics: Endometrial Hyperplasia; Estrone; Female; Humans; Pyometra; Suppuration; Uterus

1963
DRUGS FOR FUNCTIONAL UTERINE BLEEDING.
    Canadian Medical Association journal, 1964, Nov-28, Volume: 91

    Topics: Contraceptive Agents; Contraceptives, Oral; Diethylstilbestrol; Dosage Forms; Drug Therapy; Dydroges

1964
STEROID SYNTHESIS IN ABNORMAL OVARIES. II. GRANULOSA CELL TUMOR.
    American journal of obstetrics and gynecology, 1964, Dec-15, Volume: 90

    Topics: Androgens; Chromatography; Corpus Luteum Hormones; Dehydroepiandrosterone; Endometrial Hyperplasia;

1964
The polycystic ovary. VII. Intractable uterine bleeding and endometrial hyperplasia possibly related to an extraovarian source of oestrogen.
    Acta endocrinologica, 1967, Volume: 54, Issue:3

    Topics: 17-Ketosteroids; Adrenal Glands; Adult; Androgens; Chromatography; Cysts; Endometrial Hyperplasia; E

1967
Estrone and dehydroepiandrosterone sulfatase activities in normal and pathological human endometrium biopsies.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:4

    Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Endometrial Hyperplasia; Endometrium; Estron

1983
Behavior of some steroids in endometrial adenomatous and atypical hyperplasia.
    European journal of gynaecological oncology, 1983, Volume: 4, Issue:2

    Topics: Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Endometrial Hyperplasia; Estradiol; Estro

1983
[Studies on the early diagnosis of endometrial carcinoma. Analysis of risk factors and cytological approach].
    Nihon Sanka Fujinka Gakkai zasshi, 1984, Volume: 36, Issue:6

    Topics: Adult; Aged; Cytodiagnosis; Endometrial Hyperplasia; Estrone; Female; Humans; Menopause; Middle Aged

1984
Plasma androstenedione and oestrone levels before and after the menopause. I. Glandular hyperplasia and adenocarcinoma of the endometrium.
    Maturitas, 1982, Volume: 4, Issue:1

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aging; Androstenedione; Endometrial Hyperplasia; Estrone; F

1982
Aromatization of androstenedione to estrone by human adipose tissue in vitro. Correlation with adipose tissue mass, age, and endometrial neoplasia.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 53, Issue:1

    Topics: Adipose Tissue; Adult; Aged; Aging; Androstenedione; Aromatase; Endometrial Hyperplasia; Estrone; Fe

1981
Studies of oestrogen metabolism in postmenopausal women with cancer.
    Journal of steroid biochemistry, 1981, Volume: 15

    Topics: Adipose Tissue; Aged; Androstenedione; Body Weight; Breast Neoplasms; Endometrial Hyperplasia; Estra

1981
Ultrastructural features of endometrial atypical adenomatous hyperplasia and adenocarcinomas and the plasma level of estrogens.
    Gynecologic oncology, 1980, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Endometrial Hyperplasia; Estradiol; Estriol; Estroge

1980
Enhancing effects of estrogens on endometrial carcinogenesis initiated by N-methyl-N-nitrosourea in ICR mice.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:9

    Topics: Adenocarcinoma; Animals; Endometrial Hyperplasia; Endometrial Neoplasms; Estradiol; Estriol; Estrone

1993
The effects of oestrogens and progestogens on the postmenopausal endometrium.
    Maturitas, 1978, Volume: 1, Issue:2

    Topics: Endometrial Hyperplasia; Endometrium; Estrogens; Estrone; Female; Humans; Menopause; Menstruation; M

1978
Plasma levels of oestrone and oestradiol-17beta in postmenopausal women.
    British journal of obstetrics and gynaecology, 1979, Volume: 86, Issue:1

    Topics: Adult; Age Factors; Aged; Body Weight; Endometrial Hyperplasia; Estradiol; Estrogens; Estrone; Femal

1979
Origin of estrogen in a postmenopausal woman with a nonendocrine tumor of the ovary and endometrial hyperplasia.
    Obstetrics and gynecology, 1976, Volume: 47, Issue:6

    Topics: Androgens; Androstenedione; Castration; Cystadenoma; Endometrial Hyperplasia; Estrogens; Estrone; Fe

1976
Proceedings: Endocrine factors in the aetiology of cystic hyperplasia of endometrium.
    The Journal of endocrinology, 1975, Volume: 64, Issue:3

    Topics: Adult; Cysts; Endometrial Hyperplasia; Estradiol; Estrogens; Estrone; Female; Follicle Stimulating H

1975
Treatment of endometrial hyperplasia with cyproterone acetate histological and hormonal aspects.
    Acta obstetricia et gynecologica Scandinavica, 1986, Volume: 65, Issue:7

    Topics: Androgen Antagonists; Androstenedione; Cyproterone; Cyproterone Acetate; Endometrial Hyperplasia; Es

1986
Prevention of endometrial abnormalities.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1986, Volume: 134

    Topics: Endometrial Hyperplasia; Estradiol; Estriol; Estrogens; Estrogens, Conjugated (USP); Estrone; Female

1986
Increased extraction of estrogens in human endometrial hyperplasia and carcinoma.
    Cancer detection and prevention, 1988, Volume: 13, Issue:2

    Topics: Adenocarcinoma; Endometrial Hyperplasia; Endometrium; Estradiol; Estrone; Female; Humans; Perfusion;

1988
Preliminary report on postmenopausal endometrial hyperplasia treatment with Danazol: histological and endocrinological aspects.
    Cancer detection and prevention, 1986, Volume: 9, Issue:3-4

    Topics: Danazol; Endometrial Hyperplasia; Estrone; Female; Humans; Menopause; Middle Aged; Pregnadienes

1986
Estrogen production and metabolism in normal postmenopausal women and postmenopausal women with breast or endometrial cancer.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:11

    Topics: Aged; Body Weight; Breast Neoplasms; Endometrial Hyperplasia; Estradiol; Estrone; Female; Humans; Me

1986
Plasma estrogens in postmenopausal women.
    American journal of obstetrics and gynecology, 1973, Aug-15, Volume: 116, Issue:8

    Topics: Adult; Age Factors; Aged; Body Weight; Castration; Diabetes Mellitus; Endometrial Hyperplasia; Endom

1973
[Results of treatment of juvenile hemorrhagic metropathy with the authors method of hormone therapy, consisting of a combination of estrogen and progesterone].
    Akusherstvo i ginekologiia, 1973, Volume: 12, Issue:1

    Topics: Curettage; Drug Synergism; Endometrial Hyperplasia; Estrone; Female; Humans; Menorrhagia; Metrorrhag

1973