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estrone and Atrophy

estrone has been researched along with Atrophy in 22 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"To study the relationship between ovarian production of estrone (E ), estradiol (E2), testosterone (T), and androstenedione (A) and the ovarian degree of stromal hyperplasia in postmenopausal women."7.70Relationship between ovarian production of estrone, estradiol, testosterone, and androstenedione and the ovarian degree of stromal hyperplasia in postmenopausal women. ( de Jong, FH; Evers, JL; Heineman, MJ; Koudstaal, J; Sluijmer, AV; Theunissen, PH, 1998)
"Vaginal promestriene was tested in gynecological cancer patients who suffered from severe vaginal dryness and dyspareunia."5.16Effect of one-month treatment with vaginal promestriene on serum estrone sulfate levels in cancer patients: a pilot study. ( Corona, G; Del Pup, L; Postruznik, D, 2012)
" Daily oral MPG (1000 mg/kg body weight) for 2 weeks significantly recovered uterine and adrenal gland atrophy and restored serum estradiol, estrone and progesterone levels that were decreased in rats by bilateral ovariectomy."3.76Estrogenic effects of the herbal formula, menoprogen, in ovariectomized rats. ( Chung, MH; Hattori, M; Lu, Y; Ma, H; Nishihara, T, 2010)
"To study the relationship between ovarian production of estrone (E ), estradiol (E2), testosterone (T), and androstenedione (A) and the ovarian degree of stromal hyperplasia in postmenopausal women."3.70Relationship between ovarian production of estrone, estradiol, testosterone, and androstenedione and the ovarian degree of stromal hyperplasia in postmenopausal women. ( de Jong, FH; Evers, JL; Heineman, MJ; Koudstaal, J; Sluijmer, AV; Theunissen, PH, 1998)
"Plasma levels of oestrone and oestradiol-17beta were determined at 20 or 30 minute intervals for up to 24 hours in 26 postmenopausal or ovariectomised women of similar age, weight, and number of years since menopause or operation."3.66Relation between plasma oestrone and oestradiol and climacteric symptoms. ( Hutton, JD; Jacobs, HS; James, VH; Murray, MA, 1978)
"The finding of this study shows that lower dosage of piperazinyl estrone has effect on preventing the bone losses in OVX rats, while the bone formation and the uterus are not affected, thus supporting the hypothesis that piperazinyl estrone has the potential to prevent postmenopausal bone loss in women with less side effects."1.32[Piperazinyl estrone prevents bone loss in ovariectomized rats]. ( Chen, HQ; Hu, B; Huang, LF; Li, QN; Weng, LL; Zheng, H, 2003)
"Tamoxifen treatment, on the other hand, produced an increase in both the number and crowding of the endometrial glands and a mild atrophy of the myometrial layer."1.30Comparative effects of 28-day treatment with the new anti-estrogen EM-800 and tamoxifen on estrogen-sensitive parameters in intact mice. ( Belanger, A; Gauthier, S; Labrie, C; Labrie, F; Luo, S; Martel, C; Mérand, Y; Sourla, A, 1997)
"Estrone levels were not measurable with a sensitive RIA technique."1.28Endogenous estrogen levels in postmenopausal women with severe urogenital atrophy. ( Heimer, G; Nilsson, K, 1992)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199010 (45.45)18.7374
1990's6 (27.27)18.2507
2000's2 (9.09)29.6817
2010's4 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ke, Y1
Bélanger, A2
Simard, JN1
Gonthier, R1
Martel, C2
Vaillancourt, M1
Labrie, F2
Ma, H1
Chung, MH1
Lu, Y1
Nishihara, T1
Hattori, M1
Dorr, MB1
Nelson, AL1
Mayer, PR1
Ranganath, RP1
Norris, PM1
Helzner, EC1
Preston, RA1
Del Pup, L1
Postruznik, D1
Corona, G1
Li, QN1
Weng, LL1
Huang, LF1
Hu, B1
Chen, HQ1
Zheng, H1
Vardy, MD1
Lindsay, R1
Scotti, RJ1
Mikhail, M1
Richart, RM1
Nieves, J1
Zion, M1
Cosman, F1
Luisi, M1
Franchi, F1
Kicovic, PM1
Notelovitz, M1
Aiman, J1
Brenner, PF1
MacDonald, PC1
Handa, VL1
Bachus, KE1
Johnston, WW1
Robboy, SJ1
Hammond, CB1
Naessen, T1
Berglund, L1
Ulmsten, U1
Luo, S1
Sourla, A1
Gauthier, S1
Mérand, Y1
Labrie, C1
Sluijmer, AV1
Heineman, MJ1
Koudstaal, J1
Theunissen, PH1
de Jong, FH1
Evers, JL1
Hutton, JD1
Jacobs, HS1
Murray, MA1
James, VH1
Studd, J1
Nilsson, K2
Heimer, G2
Varma, TR1
Trévoux, R1
De Brux, J1
Castanier, M1
Nahoul, K1
Soule, JP1
Scholler, R1
Weniger, JP1
Aylward, M1
Holly, F1
Parker, RJ1
Procopé, BJ1
Adlercreutz, H1

Trials

6 trials available for estrone and Atrophy

ArticleYear
Plasma estrogen concentrations after oral and vaginal estrogen administration in women with atrophic vaginitis.
    Fertility and sterility, 2010, Volume: 94, Issue:6

    Topics: Administration, Intravaginal; Administration, Oral; Aged; Atrophy; Cross-Over Studies; Drug Administ

2010
Effect of one-month treatment with vaginal promestriene on serum estrone sulfate levels in cancer patients: a pilot study.
    Maturitas, 2012, Volume: 72, Issue:1

    Topics: Adult; Aged; Atrophy; Dyspareunia; Estradiol; Estrogens; Estrone; Female; Genital Neoplasms, Female;

2012
Short-term urogenital effects of raloxifene, tamoxifen, and estrogen.
    American journal of obstetrics and gynecology, 2003, Volume: 189, Issue:1

    Topics: Aged; Atrophy; Double-Blind Method; Estradiol; Estrogens; Estrogens, Conjugated (USP); Estrone; Fema

2003
Bone loss in elderly women prevented by ultralow doses of parenteral 17beta-estradiol.
    American journal of obstetrics and gynecology, 1997, Volume: 177, Issue:1

    Topics: Administration, Intravaginal; Aged; Aging; Alkaline Phosphatase; Analysis of Variance; Atrophy; Bone

1997
Low-dose oestradiol in the treatment of urogenital oestrogen deficiency--a pharmacokinetic and pharmacodynamic study.
    Maturitas, 1992, Volume: 15, Issue:2

    Topics: Administration, Intravaginal; Aged; Atrophy; Double-Blind Method; Epithelium; Estradiol; Estrone; Fe

1992
An evaluation of clinical response to piperazine oestrone sulphate ('Harmogen') in menopause patients.
    Current medical research and opinion, 1974, Volume: 2, Issue:7

    Topics: Adult; Amenorrhea; Atrophy; Clinical Trials as Topic; Estradiol Congeners; Estrogens; Estrogens, Con

1974

Other Studies

16 other studies available for estrone and Atrophy

ArticleYear
Concentration range of serum sex steroids in normal postmenopausal women and those with diagnosis of vulvovaginal atrophy.
    Menopause (New York, N.Y.), 2018, Volume: 25, Issue:3

    Topics: Aged; Androsterone; Atrophy; Case-Control Studies; Clinical Trials as Topic; Dehydroepiandrosterone

2018
Estrogenic effects of the herbal formula, menoprogen, in ovariectomized rats.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:3

    Topics: Adrenal Glands; Animals; Atrophy; Drugs, Chinese Herbal; Estradiol; Estrone; Female; Gonadal Steroid

2010
[Piperazinyl estrone prevents bone loss in ovariectomized rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:3

    Topics: Animals; Atrophy; Bone Density; Estradiol Congeners; Estrone; Female; Organ Size; Osteogenesis; Oste

2003
A group-comparative study of effects of Ovestin cream versus Premarin cream in post-menopausal women with vaginal atrophy.
    Maturitas, 1980, Volume: 2, Issue:4

    Topics: Aged; Atrophy; Estradiol; Estrogens, Conjugated (USP); Estrone; Female; Follicle Stimulating Hormone

1980
When and how to use estrogen therapy in women over 60.
    Geriatrics, 1980, Volume: 35, Issue:4

    Topics: Aged; Atrophy; Cystitis; Dose-Response Relationship, Drug; Estradiol; Estradiol Congeners; Estrogens

1980
Androgen and estrogen production in elderly men with gynecomastia and testicular atrophy after mumps orchitis.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:2

    Topics: Aged; Androstenedione; Atrophy; Estradiol; Estrone; Follicle Stimulating Hormone; Gynecomastia; Huma

1980
Vaginal administration of low-dose conjugated estrogens: systemic absorption and effects on the endometrium.
    Obstetrics and gynecology, 1994, Volume: 84, Issue:2

    Topics: Administration, Intravaginal; Aged; Atrophy; Biopsy; Blood Flow Velocity; Cell Division; Endometrium

1994
Comparative effects of 28-day treatment with the new anti-estrogen EM-800 and tamoxifen on estrogen-sensitive parameters in intact mice.
    International journal of cancer, 1997, Nov-04, Volume: 73, Issue:3

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Atrophy; Benzopyrans; Drug Administratio

1997
Relationship between ovarian production of estrone, estradiol, testosterone, and androstenedione and the ovarian degree of stromal hyperplasia in postmenopausal women.
    Menopause (New York, N.Y.), 1998,Winter, Volume: 5, Issue:4

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Androstenedione; Atrophy; Estradiol; Estrone; Female;

1998
Relation between plasma oestrone and oestradiol and climacteric symptoms.
    Lancet (London, England), 1978, Apr-01, Volume: 1, Issue:8066

    Topics: Adult; Atrophy; Castration; Climacteric; Dyspareunia; Estradiol; Estrone; Female; Humans; Menopause;

1978
Management of the menopause.
    The Practitioner, 1976, Volume: 216, Issue:1295

    Topics: Atrophy; Climacteric; Estradiol; Estrogens; Estrogens, Conjugated (USP); Estrone; Ethinyl Estradiol;

1976
Endogenous estrogen levels in postmenopausal women with severe urogenital atrophy.
    Gynecologic and obstetric investigation, 1992, Volume: 34, Issue:4

    Topics: Atrophy; Circadian Rhythm; Estradiol; Estrone; Female; Humans; Menopause; Middle Aged; Urethra; Vagi

1992
Effect of long-term therapy with estrogen and progesterone on the endometrium of post-menopausal women.
    Acta obstetricia et gynecologica Scandinavica, 1985, Volume: 64, Issue:1

    Topics: Aged; Atrophy; Contraceptives, Oral, Combined; Dose-Response Relationship, Drug; Drug Therapy, Combi

1985
Endometrium and plasma hormone profile in the peri-menopause and post-menopause.
    Maturitas, 1986, Volume: 8, Issue:4

    Topics: Atrophy; Endometrium; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Humans; Luteinizing

1986
[Secretion of estrone, estradiol, estriol, and epiestriol by the atrophied right gonad of the female chick embryo cultivated in vitro].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1969, Feb-08, Volume: 162, Issue:7

    Topics: Acetates; Animals; Atrophy; Carbon Isotopes; Chick Embryo; Chromatography, Thin Layer; Culture Techn

1969
Studies on the influence of age on oestrogens in post-menopausal women with atrophic endometrium and normal liver function.
    Acta endocrinologica, 1969, Volume: 62, Issue:3

    Topics: Age Factors; Aged; Aging; Atrophy; Castration; Endometrium; Estradiol; Estriol; Estrogens; Estrone;

1969