Compounds > estrone-3-o-sulfamate
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estrone-3-o-sulfamate and Breast Neoplasms

estrone-3-o-sulfamate has been researched along with Breast Neoplasms in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (27.27)18.2507
2000's10 (45.45)29.6817
2010's5 (22.73)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Howarth, NM; Potter, BV; Purohit, A; Reed, MJ1
Potter, BV; Purohit, A; Reed, MJ; Woo, LW1
Hejaz, HA; Mahon, MF; Potter, BV; Purohit, A; Reed, MJ1
Billich, A; Nussbaumer, P; Winiski, AP1
De Simone, G; Di Fiore, A; Leblond, B; Leese, MP; Newman, SP; Potter, BV; Purohit, A; Reed, MJ; Smith, A; Supuran, CT1
Dahse, HM; Gräfe, U; Härtl, A; Jütten, P; Schumann, W1
Kim, BM; Liu, Y; Mostafa, Y; Phan, CM; Taylor, SD1
Potter, BV; Thomas, MP1
Jaggi, AS; Shah, R; Singh, D; Singh, J; Singh, N1
Daśko, M; Demkowicz, S; Kubiński, K; Masłyk, M; Misiak, M; Przybyłowska, M; Rachon, J; Składanowski, A1
Biernacki, K; Ciupak, O; Daśko, M; Demkowicz, S; Kozak, W; Kubiński, K; Martyna, A; Masłyk, M; Nocentini, A; Rachon, J; Rak, J; Śliwka-Kaszyńska, M; Supuran, CT; Świtalska, M; Wietrzyk, J1
Ishida, H; Nakata, T; Shiotsu, Y1
Kabler, H; Li, PK; Sarap, J; Selcer, KW; Xiao, Z1
Chander, SK; Fenton, JC; Fischer, DS; Potter, BV; Purohit, A; Reed, MJ; Woo, LW1
Fujii, T; Iwashita, S; Koizumi, N; Nakagawa, T; Okada, M; Takegawa, S1
Newman, SP; Potter, BV; Purohit, A; Reed, MJ; Woo, LW1
Leblond, B; Leese, MP; Newman, SP; Potter, BV; Purohit, A; Reed, MJ1
Howarth, NM; Potter, BV; Purohit, A; Reed, MJ; Williams, GJ1
Duncan, LJ; Potter, BV; Purohit, A; Reed, MJ; Roberts, CJ; Singh, A; Williams, GJ1
Hejaz, HA; Hummelinck, AE; Potter, BV; Purohit, A; Reed, MJ; Vernon, KA; Woo, LW1
Malini, B; Potter, BV; Purohit, A; Reed, MJ; Woo, LL1
MacCarthy-Morrogh, L; Packham, G; Purohit, A; Reed, MJ; Townsend, PA1

Reviews

4 review(s) available for estrone-3-o-sulfamate and Breast Neoplasms

ArticleYear
Sulfatase inhibitors for recidivist breast cancer treatment: A chemical review.
    European journal of medicinal chemistry, 2016, May-23, Volume: 114

    Topics: Breast Neoplasms; Enzyme Inhibitors; Estrogens; Female; Humans; Neoplasm Recurrence, Local; Sulfatases; Sulfonic Acids

2016
[Steroid sulfatase inhibitor].
    Nihon rinsho. Japanese journal of clinical medicine, 2010, Volume: 68, Issue:6

    Topics: Animals; Breast Neoplasms; Clinical Trials as Topic; Coumarins; Drug Design; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Female; Humans; Steryl-Sulfatase; Sulfonamides

2010
Steroid sulfatase: molecular biology, regulation, and inhibition.
    Endocrine reviews, 2005, Volume: 26, Issue:2

    Topics: Animals; Breast Neoplasms; Clinical Trials, Phase I as Topic; Coumarins; Enzyme Inhibitors; Estrone; Female; Humans; Models, Molecular; Neoplasms, Hormone-Dependent; Steryl-Sulfatase; Sulfonamides; Sulfonic Acids

2005
The role of cytokines and sulphatase inhibitors in regulating oestrogen synthesis in breast tumours.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 53, Issue:1-6

    Topics: Breast Neoplasms; Cytokines; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol Dehydrogenases; Estrogens; Estrone; Fibroblast Growth Factor 2; Growth Substances; Humans; In Vitro Techniques; Insulin-Like Growth Factor I; Interleukin-2; Lymphocytes; Macrophages; Sulfatases; Transforming Growth Factor alpha; Tumor Cells, Cultured

1995

Other Studies

18 other study(ies) available for estrone-3-o-sulfamate and Breast Neoplasms

ArticleYear
Estrone sulfamates: potent inhibitors of estrone sulfatase with therapeutic potential.
    Journal of medicinal chemistry, 1994, Jan-21, Volume: 37, Issue:2

    Topics: Breast Neoplasms; Cell Division; Drug Screening Assays, Antitumor; Estrone; Humans; Sulfatases; Sulfonic Acids; Tumor Cells, Cultured

1994
Active site directed inhibition of estrone sulfatase by nonsteroidal coumarin sulfamates.
    Journal of medicinal chemistry, 1996, Mar-29, Volume: 39, Issue:7

    Topics: Binding Sites; Breast Neoplasms; Coumarins; Enzyme Inhibitors; Humans; Microsomes; Placenta; Sulfatases; Sulfonamides; Tumor Cells, Cultured

1996
Synthesis and biological activity of the superestrogen (E)-17-oximino-3-O-sulfamoyl-1,3,5(10)-estratriene: x-ray crystal structure of (E)-17-oximino-3-hydroxy-1,3,5(10)-estratriene.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Animals; Antineoplastic Agents; Arylsulfatases; Breast Neoplasms; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Estrone; Female; Humans; Liver; Neoplasms, Hormone-Dependent; Ovariectomy; Oximes; Rats; Steryl-Sulfatase; Tumor Cells, Cultured; Uterus

1999
Estrogenic potential of 2-alkyl-4-(thio)chromenone 6-O-sulfamates: potent inhibitors of human steroid sulfatase.
    Journal of medicinal chemistry, 2003, Nov-06, Volume: 46, Issue:23

    Topics: Benzopyrans; Binding, Competitive; Breast Neoplasms; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Fluorescence Polarization; Humans; Ligands; Receptors, Estrogen; Steryl-Sulfatase; Structure-Activity Relationship; Sulfonic Acids

2003
2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity.
    Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26

    Topics: Animals; Antineoplastic Agents; Binding Sites; Breast Neoplasms; Carbonic Anhydrase II; Carcinoma, Lewis Lung; Cell Proliferation; Crystallography, X-Ray; Estradiol; Female; Humans; Mice; Mice, Nude; Models, Molecular; Neovascularization, Pathologic; Steryl-Sulfatase; Structure-Activity Relationship; Sulfonic Acids; Survival Rate; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zinc

2006
Thiosemicarbazones of formyl benzoic acids as novel potent inhibitors of estrone sulfatase.
    Journal of medicinal chemistry, 2007, Jul-26, Volume: 50, Issue:15

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Chickens; Female; Humans; In Vitro Techniques; Microsomes; Neoplasms, Hormone-Dependent; Placenta; Salicylates; Structure-Activity Relationship; Sulfatases; Thiosemicarbazones; Toxicity Tests, Acute

2007
Inhibition of steroid sulfatase with 4-substituted estrone and estradiol derivatives.
    Bioorganic & medicinal chemistry, 2011, Oct-15, Volume: 19, Issue:20

    Topics: Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrone; Female; Humans; Kinetics; Placenta; Pregnancy; Steryl-Sulfatase

2011
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.
    Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19

    Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Discovery; Endometriosis; Estrone; Female; Humans; Male; Molecular Targeted Therapy; Prostatic Neoplasms; Steryl-Sulfatase; Sulfonic Acids; Tubulin Modulators

2015
Synthesis and biological evaluation of fluorinated N-benzoyl and N-phenylacetoyl derivatives of 3-(4-aminophenyl)-coumarin-7-O-sulfamate as steroid sulfatase inhibitors.
    European journal of medicinal chemistry, 2017, Mar-10, Volume: 128

    Topics: Breast Neoplasms; Coumarins; Enzyme Inhibitors; Female; Halogenation; Humans; Placenta; Pregnancy; Receptors, Estrogen; Steryl-Sulfatase; Structure-Activity Relationship; Sulfonamides; Tumor Cells, Cultured

2017
Development of Sulfamoylated 4-(1-Phenyl-1
    Journal of medicinal chemistry, 2022, 03-24, Volume: 65, Issue:6

    Topics: Animals; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; MCF-7 Cells; Mice; Phenol; Steryl-Sulfatase; Structure-Activity Relationship

2022
Inhibition of steryl sulfatase activity in LNCaP human prostate cancer cells.
    Steroids, 2002, Volume: 67, Issue:10

    Topics: Arylsulfatases; Breast Neoplasms; Danazol; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Estrone; Female; Humans; Kinetics; Male; Microsomes; Prostatic Neoplasms; Steryl-Sulfatase; Sulfonamides; Tumor Cells, Cultured; Tyramine

2002
Novel D-ring modified steroid derivatives as potent, non-estrogenic, steroid sulfatase inhibitors with in vivo activity.
    The Journal of steroid biochemistry and molecular biology, 2003, Volume: 84, Issue:2-3

    Topics: Animals; Arylsulfatases; Breast Neoplasms; Chromatography, Thin Layer; Enzyme Inhibitors; Estrogens; Estrone; Female; Inhibitory Concentration 50; Liver; Models, Chemical; Ovary; Rats; Rats, Wistar; Steryl-Sulfatase; Time Factors

2003
Development of novel steroid sulfatase inhibitors. I. Synthesis and biological evaluation of biphenyl-4-O-sulfamates.
    The Journal of steroid biochemistry and molecular biology, 2003, Volume: 87, Issue:2-3

    Topics: Animals; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Enzyme Inhibitors; Estradiol; Estrogen Receptor alpha; Estrone; Female; Humans; Liver; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Steryl-Sulfatase; Structure-Activity Relationship; Sulfonic Acids; Uterus

2003
Anti-cancer activities of novel D-ring modified 2-substituted estrogen-3-O-sulfamates.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 94, Issue:1-3

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Line, Tumor; Estrone; Female; Humans; Kinetics; Structure-Activity Relationship

2005
Inactivation of steroid sulfatase by an active site-directed inhibitor, estrone-3-O-sulfamate.
    Biochemistry, 1995, Sep-12, Volume: 34, Issue:36

    Topics: Arylsulfatases; Binding Sites; Breast Neoplasms; Enzyme Inhibitors; Estrone; Female; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Microsomes; Placenta; Steryl-Sulfatase; Substrate Specificity; Tumor Cells, Cultured

1995
The development of A-ring modified analogues of oestrone-3-O-sulphamate as potent steroid sulphatase inhibitors with reduced oestrogenicity.
    The Journal of steroid biochemistry and molecular biology, 1998, Volume: 64, Issue:5-6

    Topics: Animals; Arylsulfatases; Breast Neoplasms; Enzyme Inhibitors; Estrone; Female; Microsomes; Molecular Structure; Organ Size; Ovariectomy; Placenta; Rats; Rats, Inbred Strains; Steryl-Sulfatase; Uterus

1998
Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates.
    Chemistry & biology, 2000, Volume: 7, Issue:10

    Topics: Alanine; Antineoplastic Agents; Arylsulfatases; Binding Sites; Breast Neoplasms; Coumarins; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Estrone; Female; Glycine; Heterocyclic Compounds, 3-Ring; Humans; Hydrogen Bonding; Kinetics; Microsomes; Models, Molecular; Placenta; Postmenopause; Steryl-Sulfatase; Structure-Activity Relationship; Sulfatases; Sulfonamides; Sulfonic Acids

2000
Differential effects of estrone and estrone-3-O-sulfamate derivatives on mitotic. Arrest, apoptosis, and microtubule assembly in human breast cancer cells.
    Cancer research, 2000, Oct-01, Volume: 60, Issue:19

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Division; Estrone; Humans; Hydroxyestrones; Microtubules; Mitosis; Tubulin; Tumor Cells, Cultured

2000