Page last updated: 2024-11-06

estriol and Melanoma

estriol has been researched along with Melanoma in 3 studies

hormonin: estrogen replacement; each tablet contains 600 ug micronized 17beta-estradiol, 270 ug estriol and 1.4 mg estrone
chlorapatite : A phosphate mineral with the formula Ca5(PO4)3Cl.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"Estriol was more potent, with the maximal blockade occurring at approximately 0."5.27Inhibition of imidazole-induced tyrosinase activity by estradiol and estriol in cultured B16/C3 melanoma cells. ( Blackmon, B; Carland, KA; Kline, EL; Smith, TJ, 1988)
" estrone, 17-beta-estradiol and estriol, was studied in a melanoma cell line producing a tissue-type plasminogen activator (t-PA)."3.67Estrogen regulation of tissue plasminogen activator in a human melanoma cell line. ( Astedt, B; Kjaeldgaard, A; Larsson, B, 1986)
" In the present study, we have compared the pharmacokinetic profiles and metabolism of 2-MeOE2 and its sulphamoylated derivative, 2-methoxyoestradiol-bis-sulphamate (2-MeOE2bisMATE), in adult female rats."1.32Pharmacokinetics and efficacy of 2-methoxyoestradiol and 2-methoxyoestradiol-bis-sulphamate in vivo in rodents. ( Chander, SK; Ireson, CR; Leese, MP; Newman, SP; Parish, D; Perera, S; Potter, BV; Purohit, A; Reed, MJ; Smith, AC, 2004)
"Estriol was more potent, with the maximal blockade occurring at approximately 0."1.27Inhibition of imidazole-induced tyrosinase activity by estradiol and estriol in cultured B16/C3 melanoma cells. ( Blackmon, B; Carland, KA; Kline, EL; Smith, TJ, 1988)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ireson, CR1
Chander, SK1
Purohit, A1
Perera, S1
Newman, SP1
Parish, D1
Leese, MP1
Smith, AC1
Potter, BV1
Reed, MJ1
Kjaeldgaard, A1
Larsson, B1
Astedt, B1
Kline, EL1
Smith, TJ1
Carland, KA1
Blackmon, B1

Other Studies

3 other studies available for estriol and Melanoma

ArticleYear
Pharmacokinetics and efficacy of 2-methoxyoestradiol and 2-methoxyoestradiol-bis-sulphamate in vivo in rodents.
    British journal of cancer, 2004, Feb-23, Volume: 90, Issue:4

    Topics: 2-Methoxyestradiol; Administration, Oral; Animals; Biological Availability; Breast Neoplasms; Dose-R

2004
Estrogen regulation of tissue plasminogen activator in a human melanoma cell line.
    Thrombosis research, 1986, May-01, Volume: 42, Issue:3

    Topics: Cell Line; Depression, Chemical; Dose-Response Relationship, Drug; Estradiol; Estriol; Estrogens; Es

1986
Inhibition of imidazole-induced tyrosinase activity by estradiol and estriol in cultured B16/C3 melanoma cells.
    Journal of cellular physiology, 1988, Volume: 134, Issue:3

    Topics: Animals; Catechol Oxidase; Cell Division; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Ind

1988