Page last updated: 2024-11-06

estriol and Choriocarcinoma

estriol has been researched along with Choriocarcinoma in 12 studies

hormonin: estrogen replacement; each tablet contains 600 ug micronized 17beta-estradiol, 270 ug estriol and 1.4 mg estrone
chlorapatite : A phosphate mineral with the formula Ca5(PO4)3Cl.

Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

Research Excerpts

ExcerptRelevanceReference
"The estradiol (E2) to estriol (E3) ratio during human pregnancy depends on fetal liver hydroxylation of fetal adrenal dehydroepiandrosterone sulfate (DHEAS) and conversion by the trophoblast of DHEAS and 16 alpha-hydroxy-DHEAS (16 OH-DHEAS) to estrone (E1), estradiol (E2), and estriol (E3), respectively."7.67Competitive studies with dehydroepiandrosterone sulfate and 16 alpha-hydroxydehydroepiandrosterone sulfate in cultured human choriocarcinoma JEG-3 cells: effect on estrone, 17 beta-estradiol, and estriol secretion. ( Benveniste, R; Ilekis, J; Scommegna, A; Zbella, EA, 1986)
"The estradiol (E2) to estriol (E3) ratio during human pregnancy depends on fetal liver hydroxylation of fetal adrenal dehydroepiandrosterone sulfate (DHEAS) and conversion by the trophoblast of DHEAS and 16 alpha-hydroxy-DHEAS (16 OH-DHEAS) to estrone (E1), estradiol (E2), and estriol (E3), respectively."3.67Competitive studies with dehydroepiandrosterone sulfate and 16 alpha-hydroxydehydroepiandrosterone sulfate in cultured human choriocarcinoma JEG-3 cells: effect on estrone, 17 beta-estradiol, and estriol secretion. ( Benveniste, R; Ilekis, J; Scommegna, A; Zbella, EA, 1986)
"Investigation of the effects of OCs on neoplasia is not easy; currently 4 investigative methods are used: 1) case reports, 2) disease rate and trends, 3) case-control studies, which are the main source of careful retrospective information, and 4) cohort studies, which compare the incidence of disease in patients exposed to suspected environmental factors, and in those who are not exposed."2.36Neoplasia and hormonal contraception. ( Huggins, GR, 1981)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199012 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huggins, GR2
Maeyama, M1
Ifuku, M1
Nakahara, K1
Giuntoli, RL1
Zbella, EA1
Ilekis, J1
Scommegna, A1
Benveniste, R1
Godden, JD1
Garnett, ES1
Sommerville, IF1
Bagshawe, KD1
Barlow, JJ1
Goldstein, DP1
Reid, DE1
Samaan, NA1
McRoberts, WA1
Smith, JP1
Myers, LG1
Pattillo, RA1
Hussa, RO1
Huang, WY1
Delfs, E1
Mattingly, RF1
Kelly, WG1
Rizkallah, TH1
Lindenmeyer, D1
Tomanek, M1
Körner, F1
Akasu, F1
Kuwabara, S1
Iwakami, T1
Sumitani, J1
Brinck-Johnsen, T1
Solc, J1
Galton, VA1

Reviews

2 reviews available for estriol and Choriocarcinoma

ArticleYear
Neoplasia and hormonal contraception.
    Clinical obstetrics and gynecology, 1981, Volume: 24, Issue:3

    Topics: Animals; Breast Diseases; Breast Neoplasms; Choriocarcinoma; Contraceptives, Oral; Contraceptives, O

1981
Oral contraceptives and neoplasia.
    Fertility and sterility, 1979, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Breast Neoplasms; Choriocarcinoma; Chronic Disease; Contraceptives, Oral; Contrac

1979

Trials

1 trial available for estriol and Choriocarcinoma

ArticleYear
The effect of choriocarcinoma on serum thyroid hormone-binding capacity.
    The Journal of endocrinology, 1967, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Blood Proteins; Choriocarcinoma; Chorionic Gonadotropin; Clinical Trials as Topic

1967

Other Studies

9 other studies available for estriol and Choriocarcinoma

ArticleYear
Steroidogenesis in cerebral metastatic chorionepithelioma tissue in vitro.
    The Journal of endocrinology, 1975, Volume: 65, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Brain Neoplasms; Choriocarcinoma; Dehydroepiandroster

1975
Competitive studies with dehydroepiandrosterone sulfate and 16 alpha-hydroxydehydroepiandrosterone sulfate in cultured human choriocarcinoma JEG-3 cells: effect on estrone, 17 beta-estradiol, and estriol secretion.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 63, Issue:3

    Topics: Cells, Cultured; Choriocarcinoma; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol;

1986
A study of in vitro estrogen biosynthesis and production rates in normal pregnancy, hydatidiform mole and choriocarcinoma.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:7

    Topics: Adolescent; Adult; Carbon Isotopes; Choriocarcinoma; Dehydroepiandrosterone; Estradiol; Estriol; Est

1967
Metabolic changes in women with trophoblastic disease and with intrauterine fetal death compared with metabolic changes during normal pregnancy.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 33, Issue:3

    Topics: Adult; Arginine; Blood Glucose; Choriocarcinoma; Estriol; Fatty Acids; Female; Fetal Death; Glucose

1971
Estrogen production by trophoblastic tumors in tissue culture.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:1

    Topics: 17-Ketosteroids; Androstanes; Cell Line; Choriocarcinoma; Chromatography; Culture Techniques; Dehydr

1972
Dissimilar isotopic ratios in urinary estrogens following simultaneous injection of delta-4-androstenedione-14C and estrone-6,7-3H.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 36, Issue:1

    Topics: 17-Ketosteroids; Aged; Androstanes; Carbon Isotopes; Carcinoma; Choriocarcinoma; Endometrium; Estrad

1973
Hormonal changes in urine and plasma by hormone-producing testicular tumors before and after treatment.
    Acta endocrinologica. Supplementum, 1971, Volume: 152

    Topics: Choriocarcinoma; Dysgerminoma; Estradiol; Estriol; Estrone; Gonadotropins; Humans; Male; Progesteron

1971
Some opinions on causal relationship between chorioepithelioma and endocrine milieu.
    Endocrinologia japonica, 1969, Volume: 16, Issue:1

    Topics: Animals; Choriocarcinoma; Chorionic Gonadotropin; Estradiol; Estriol; Estrogens; Female; Fluorometry

1969
Urinary excretion of estrogens in women with hydatidiform mole and choriocarcinoma.
    Obstetrics and gynecology, 1970, Volume: 36, Issue:5

    Topics: Choriocarcinoma; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Hydatidiform Mole; Pregnanc

1970