Compounds > estragole
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estragole and Liver Neoplasms

estragole has been researched along with Liver Neoplasms in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dominici, L; Fatigoni, C; Levorato, S; Moretti, M; Pagiotti, R; Vannini, S; Villarini, M1
Ishii, Y; Kijima, A; Kuroda, K; Matsushita, K; Nohmi, T; Ogawa, K; Takasu, S; Umemura, T; Yokoo, Y1
Bristol, DW1
Hibi, D; Inoue, T; Ishii, Y; Jin, M; Nishikawa, A; Nohmi, T; Ogawa, K; Sakai, H; Suzuki, Y; Umemura, T; Yanai, T1
Hibi, D; Inoue, T; Ishii, Y; Jin, M; Kodama, Y; Nishikawa, A; Nohmi, T; Ogawa, K; Sakai, H; Suzuki, Y; Umemura, T; Yanai, T1
Miller, EC; Miller, JA1
Fletcher, TL; Liem, A; Miller, EC; Miller, JA; Phillips, DH; Swanson, AB1
Drinkwater, NR; Miller, EC; Miller, JA; Pitot, HC1

Reviews

1 review(s) available for estragole and Liver Neoplasms

ArticleYear
The metabolic activation and nucleic acid adducts of naturally-occurring carcinogens: recent results with ethyl carbamate and the spice flavors safrole and estragole.
    British journal of cancer, 1983, Volume: 48, Issue:1

    Topics: Adenine; Allylbenzene Derivatives; Animals; Anisoles; Biotransformation; Carcinogens, Environmental; Cricetinae; Cytidine; Dioxoles; DNA; Female; Flavoring Agents; Humans; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Rats; RNA; Safrole; Time Factors; Urethane

1983

Other Studies

7 other study(ies) available for estragole and Liver Neoplasms

ArticleYear
Investigation of the cytotoxic, genotoxic, and apoptosis-inducing effects of estragole isolated from fennel (Foeniculum vulgare).
    Journal of natural products, 2014, Apr-25, Volume: 77, Issue:4

    Topics: Acridine Orange; Allylbenzene Derivatives; Animals; Anisoles; Apoptosis; Carcinoma, Hepatocellular; DNA Damage; DNA Fragmentation; Electrophoresis; Fluorescent Dyes; Foeniculum; Hep G2 Cells; Humans; Indoles; Liver Neoplasms; Membrane Potential, Mitochondrial; Mice; Molecular Structure; Oils, Volatile

2014
Phosphorylation of protein phosphatase 2A facilitated an early stage of chemical carcinogenesis.
    Toxicology and applied pharmacology, 2017, 12-01, Volume: 336

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; DNA Adducts; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Hepatocytes; Histones; Liver Neoplasms; Male; MAP Kinase Kinase Kinases; Mutation; Phosphoproteins; Phosphorylation; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Rad51 Recombinase; Rats, Inbred F344; Rats, Transgenic; Signal Transduction; src-Family Kinases; Time Factors; Tumor Suppressor Protein p53

2017
NTP 3-month toxicity studies of estragole (CAS No. 140-67-0) administered by gavage to F344/N rats and B6C3F1 mice.
    Toxicity report series, 2011, Issue:82

    Topics: Adenoma, Liver Cell; Administration, Oral; Allylbenzene Derivatives; Anemia; Animals; Anisoles; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Body Weight; Carcinogenicity Tests; Cholangiocarcinoma; Erythrocytes; Female; Food Additives; Hepatocytes; Liver; Liver Function Tests; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Mutagenicity Tests; Organ Size; Rats; Rats, Inbred F344; Toxicity Tests

2011
Possible involvement of genotoxic mechanisms in estragole-induced hepatocarcinogenesis in rats.
    Archives of toxicology, 2012, Volume: 86, Issue:10

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Chromatography, Liquid; DNA Adducts; Dose-Response Relationship, Drug; Flavoring Agents; Glutathione S-Transferase pi; Immunohistochemistry; Liver Neoplasms; Male; Mutagens; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Tandem Mass Spectrometry; Time Factors

2012
Possible involvement of sulfotransferase 1A1 in estragole-induced DNA modification and carcinogenesis in the livers of female mice.
    Mutation research, 2012, Dec-12, Volume: 749, Issue:1-2

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Arylsulfotransferase; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Female; Flavoring Agents; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Micronucleus Tests; Mutagens

2012
Structure-activity studies of the carcinogenicities in the mouse and rat of some naturally occurring and synthetic alkenylbenzene derivatives related to safrole and estragole.
    Cancer research, 1983, Volume: 43, Issue:3

    Topics: Administration, Oral; Allylbenzene Derivatives; Animals; Anisoles; Dioxoles; Female; Injections, Intraperitoneal; Liver Neoplasms; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Rats; Rats, Inbred F344; Safrole; Structure-Activity Relationship

1983
Hepatocarcinogenicity of estragole (1-allyl-4-methoxybenzene) and 1'-hydroxyestragole in the mouse and mutagenicity of 1'-acetoxyestragole in bacteria.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:6

    Topics: Allylbenzene Derivatives; Animals; Animals, Newborn; Anisoles; Carcinogens; Carcinoma, Hepatocellular; Flavoring Agents; Glucuronates; Liver; Liver Neoplasms; Male; Mice; Mutagens; Neoplasms, Experimental; Nucleosides; Salmonella typhimurium

1976