estazolam has been researched along with Chronic Insomnia in 32 studies
Estazolam: A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than DIAZEPAM or NITRAZEPAM.
estazolam : A triazolo[4,3-a][1,4]benzodiazepine having a phenyl group at position 6 and a chloro substituent at position 8. A short-acting benzodiazepine with general properties similar to diazepam, it is given by mouth as a hypnotic in the short-term management of insomnia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the effect on chronic insomnia disorder (CID) and influences on episodic memory and sleep structure between acupuncture and estazolam tablets." | 9.34 | [Effect of acupuncture and estazolam on episodic memory and sleep structure in patients with chronic insomnia disorder: a randomized controlled trial]. ( Chen, GL; Feng, H; Liu, WJ; Liu, Y; Liu, YH; Xu, H, 2020) |
| "To analyze the somnipathy related factors in elderly patients with stroke and to compare effects of traditional Chinese medicine and estazolam on sleep and the followed nervous function." | 9.14 | [Analysis on somnipathy related factors in elderly patients with stroke and comparative study on the efficacy of treatment by traditional Chinese medicine and by estazolam]. ( Chen, XG; Li, HC; Tian, X, 2009) |
| "In this multicentre, open labeled, randomized clinical trial, 217 adult (18 - 75 years) hypertensive patients (BP range 140 mm Hg | 9.12 | [Effects of midazolam and estazolam as hypnotics in hypertensive patients with chronic insomnia: a multicentre, open labeled, randomized clinical trial]. ( Ke, YN; Wang, XL, 2006) |
| "TCM has better efficacy in treating somnipathy of hypertension patients than Estazolam." | 9.12 | [Comparative study on treatment of somnipathy in patients with hypertension by traditional Chinese medicine and by estazolam]. ( Li, HC; Ma, M; Yang, YL, 2007) |
| "To compare the effect on chronic insomnia disorder (CID) and influences on episodic memory and sleep structure between acupuncture and estazolam tablets." | 5.34 | [Effect of acupuncture and estazolam on episodic memory and sleep structure in patients with chronic insomnia disorder: a randomized controlled trial]. ( Chen, GL; Feng, H; Liu, WJ; Liu, Y; Liu, YH; Xu, H, 2020) |
| "To analyze the somnipathy related factors in elderly patients with stroke and to compare effects of traditional Chinese medicine and estazolam on sleep and the followed nervous function." | 5.14 | [Analysis on somnipathy related factors in elderly patients with stroke and comparative study on the efficacy of treatment by traditional Chinese medicine and by estazolam]. ( Chen, XG; Li, HC; Tian, X, 2009) |
| "In this multicentre, open labeled, randomized clinical trial, 217 adult (18 - 75 years) hypertensive patients (BP range 140 mm Hg | 5.12 | [Effects of midazolam and estazolam as hypnotics in hypertensive patients with chronic insomnia: a multicentre, open labeled, randomized clinical trial]. ( Ke, YN; Wang, XL, 2006) |
| "TCM has better efficacy in treating somnipathy of hypertension patients than Estazolam." | 5.12 | [Comparative study on treatment of somnipathy in patients with hypertension by traditional Chinese medicine and by estazolam]. ( Li, HC; Ma, M; Yang, YL, 2007) |
| "Cancer-related insomnia is a highly prevalent complaint in cancer patients." | 2.82 | Acupuncture for cancer-related insomnia: A systematic review and meta-analysis. ( Huang, S; Huang, Y; Lao, L; Qiu, X; Zhang, J; Zhang, Z; Zhang, ZJ, 2022) |
| "Ninety-eight patients of senile insomnia were randomized into a western medication group (30 cases), an acupuncture group (35 cases) and an integrated acupuncture and medication group (35 cases)." | 2.80 | [Senile insomnia treated with integrated acupuncture and medication therapy: a randomized controlled trial]. ( Wang, J; Wang, L; Zhang, Y, 2015) |
| " Ninety primary insomnia patients were randomly assigned to receive TIP3-2 combined with medication (n = 45) or medication only (n = 45) for 4 weeks." | 2.79 | Low Resistance Thought Induction Sleep-regulating Technique (TIP3-2) combined with medication for primary insomnia: a randomized controlled trial. ( Hong, L; Huang, YY; Li, GX; Li, T; Lin, YN; Liu, YJ; Wang, F; Wang, WD; Yan, X; Zhao, Y, 2014) |
| "Further, the relapse and recurrence rates within 3 months after respective treatments were also measured." | 2.78 | Efficacy of repetitive transcranial magnetic stimulation in the treatment of patients with chronic primary insomnia. ( Gao, D; Jiang, CG; Yi, ML; Yue, FG; Zhang, T, 2013) |
| "The Athens Insomnia Scale (AIS) was used to evaluate the clinical therapeutic effects, while the treatment emergent symptom scale (TESS) was used to evaluate adverse reactions." | 2.74 | The XIA's No. 1 sleeping Prescription for the treatment of insomnia of the deficiency type: a clinical observation of 60 cases. ( Deng, SP; Xia, CY; Zhu, PJ, 2009) |
| "Estazolam is a new benzodiazepine hypnotic agent with an intermediate half-life of 12 to 15 hours." | 2.67 | Hypnotic efficacy of estazolam compared with flurazepam in outpatients with insomnia. ( Bremner, J; Cohn, JB; Ettinger, M; Wilcox, CS, 1991) |
| "Estazolam 2." | 2.67 | Estazolam treatment of insomnia in generalized anxiety disorder: a placebo-controlled study. ( Bailey, L; Bielski, RJ; Crowder, JE; Ferguson, JM; Houston, J; Patrick, RO; Pearlman, HG; Pierce, MW; Post, GL; Shu, VS, 1991) |
| " Drug-specific adverse effects such as somnolence, dizziness, hypokinesia, and abnormal coordination occurred, but these are expected extensions of benzodiazepine pharmacologic activity." | 2.67 | Safety of estazolam. The United States clinical experience. ( Groves, LJ; Pierce, MW; Shu, VS, 1990) |
| "Estazolam is an effective treatment for situational insomnia and significantly improves sleep in patients with insomnia associated with moderately severe anxiety or depression." | 2.67 | Efficacy of estazolam. The United States clinical experience. ( Pierce, MW; Shu, VS, 1990) |
| "Outpatients complaining of insomnia were randomized to receive either estazolam 2 mg, flurazepam 30 mg or placebo for 7 consecutive nights." | 2.67 | Estazolam and flurazepam: a multicenter, placebo-controlled comparative study in outpatients with insomnia. ( Dominguez, RA; Roth, PB; Scharf, MB; Ware, JC, 1990) |
| "Flurazepam-treated patients had a significantly more severe rating of adverse reactions than did placebo-treated patients." | 2.66 | Comparative efficacy of estazolam, flurazepam, and placebo in outpatients with insomnia. ( Dominguez, RA; Goldstein, BJ; Jacobson, AF; Steinbook, RM, 1986) |
| "Insomnia is a well-recognized clinical sleep disorder in the adult population." | 1.91 | Effects of electroacupuncture on the ventral tegmental area- nucleus accumbens dopamine pathway in rats with chronic sleep deprivation. ( Liu, C; Qin, S; Wang, X; Wu, W; Xi, H, 2023) |
| "CNG can alleviate insomnia by regulating endogenous differential metabolites and further related metabolic pathways." | 1.72 | [Sleep-improving mechanism of Chaiqin Ningshen Granules in insomnia rats: based on hippocampal metabonomics]. ( Hao, XL; He, P; Jiang, JX; Li, J; Liu, C; Wu, YR; Zhang, Y; Zhang, YJ; Zhao, LR, 2022) |
| "The sleeplessness was introduced to all rats except control." | 1.56 | Pearl powder reduces sleep disturbance stress response through regulating proteomics in a rat model of sleep deprivation. ( Huang, D; Lin, J; Tong, Y; Xia, M, 2020) |
| "Rebound insomnia occurred on the first withdrawal night only for wake time and total sleep time." | 1.28 | The effects of estazolam on sleep, performance, and memory: a long-term sleep laboratory study of elderly insomniacs. ( Morris, D; Vogel, GW, 1992) |
| "Subjects with a complaint of insomnia verified by polysomnography were included in the study." | 1.27 | Chronic hypnotic efficacy of estazolam. ( Koshorek, G; Lamphere, J; Roehrs, T; Roth, T; Zorick, F, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (15.63) | 18.7374 |
| 1990's | 9 (28.13) | 18.2507 |
| 2000's | 6 (18.75) | 29.6817 |
| 2010's | 7 (21.88) | 24.3611 |
| 2020's | 5 (15.63) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, LR | 1 |
| He, P | 1 |
| Li, J | 2 |
| Zhang, YJ | 1 |
| Jiang, JX | 1 |
| Wu, YR | 1 |
| Zhang, Y | 2 |
| Liu, C | 2 |
| Hao, XL | 1 |
| Zhang, J | 1 |
| Zhang, Z | 1 |
| Huang, S | 2 |
| Qiu, X | 1 |
| Lao, L | 1 |
| Huang, Y | 1 |
| Zhang, ZJ | 1 |
| Xi, H | 1 |
| Wu, W | 2 |
| Qin, S | 1 |
| Wang, X | 1 |
| Feng, G | 1 |
| Han, M | 1 |
| Li, X | 1 |
| Geng, L | 1 |
| Miao, Y | 1 |
| Xia, M | 1 |
| Huang, D | 1 |
| Tong, Y | 1 |
| Lin, J | 1 |
| Feng, H | 1 |
| Liu, Y | 1 |
| Xu, H | 1 |
| Liu, YH | 1 |
| Chen, GL | 1 |
| Liu, WJ | 1 |
| Jiang, CG | 1 |
| Zhang, T | 1 |
| Yue, FG | 1 |
| Yi, ML | 1 |
| Gao, D | 1 |
| Wang, WD | 1 |
| Li, GX | 1 |
| Hong, L | 1 |
| Liu, YJ | 1 |
| Zhao, Y | 1 |
| Lin, YN | 1 |
| Wang, F | 1 |
| Li, T | 1 |
| Yan, X | 2 |
| Huang, YY | 1 |
| Yen, CF | 1 |
| Ko, CH | 1 |
| Chang, YP | 1 |
| Yu, CY | 1 |
| Huang, MF | 1 |
| Yeh, YC | 1 |
| Lin, JJ | 1 |
| Chen, CS | 1 |
| Wang, J | 3 |
| Wang, L | 1 |
| Li, HC | 2 |
| Chen, XG | 1 |
| Tian, X | 1 |
| Li, Y | 1 |
| Xu, BY | 1 |
| Xiao, F | 1 |
| Xia, CY | 2 |
| Deng, SP | 1 |
| Zhu, PJ | 1 |
| Wang, ZZ | 1 |
| Wang, YP | 1 |
| Yang, B | 1 |
| Wan, JP | 1 |
| Ma, C | 1 |
| Shen, Y | 1 |
| Gu, N | 1 |
| Chen, H | 1 |
| Li, S | 1 |
| Hong, Z | 1 |
| Li, H | 1 |
| Cui, R | 1 |
| Zhou, D | 1 |
| Wang, XL | 1 |
| Ke, YN | 1 |
| Yang, YL | 1 |
| Ma, M | 1 |
| Roehrs, T | 2 |
| Zorick, F | 2 |
| Lord, N | 1 |
| Koshorek, GL | 1 |
| Roth, T | 2 |
| Vogel, GW | 1 |
| Morris, D | 1 |
| Walsh, JK | 1 |
| Mahowald, MW | 1 |
| Cohn, JB | 1 |
| Wilcox, CS | 1 |
| Bremner, J | 1 |
| Ettinger, M | 1 |
| Post, GL | 1 |
| Patrick, RO | 1 |
| Crowder, JE | 1 |
| Houston, J | 1 |
| Ferguson, JM | 1 |
| Bielski, RJ | 1 |
| Bailey, L | 1 |
| Pearlman, HG | 1 |
| Shu, VS | 3 |
| Pierce, MW | 3 |
| Groves, LJ | 1 |
| Scharf, MB | 1 |
| Roth, PB | 1 |
| Dominguez, RA | 3 |
| Ware, JC | 1 |
| Goldstein, BJ | 2 |
| Jacobson, AF | 2 |
| Steinbook, RM | 2 |
| Lamphere, J | 1 |
| Koshorek, G | 1 |
| Mauro, C | 1 |
| Sperlongano, P | 1 |
2 reviews available for estazolam and Chronic Insomnia
| Article | Year |
|---|---|
Acupuncture for cancer-related insomnia: A systematic review and meta-analysis.
Topics: Acupuncture Therapy; Breast Neoplasms; China; Estazolam; Female; Humans; Sleep Initiation and Mainte | 2022 |
Clinical effectiveness of Tui Na for insomnia compared with estazolam: A systematic review and meta-analysis of randomized controlled trials.
Topics: Estazolam; Humans; Medicine, Chinese Traditional; Musculoskeletal Manipulations; Randomized Controll | 2019 |
19 trials available for estazolam and Chronic Insomnia
| Article | Year |
|---|---|
[Effect of acupuncture and estazolam on episodic memory and sleep structure in patients with chronic insomnia disorder: a randomized controlled trial].
Topics: Acupuncture Points; Acupuncture Therapy; Estazolam; Humans; Memory, Episodic; Sleep; Sleep Initiatio | 2020 |
Efficacy of repetitive transcranial magnetic stimulation in the treatment of patients with chronic primary insomnia.
Topics: Adrenocorticotropic Hormone; Adult; Anti-Anxiety Agents; Chronic Disease; Estazolam; Female; Humans; | 2013 |
Low Resistance Thought Induction Sleep-regulating Technique (TIP3-2) combined with medication for primary insomnia: a randomized controlled trial.
Topics: Adult; China; Cognitive Behavioral Therapy; Combined Modality Therapy; Estazolam; Female; Humans; Hy | 2014 |
[Senile insomnia treated with integrated acupuncture and medication therapy: a randomized controlled trial].
Topics: Acupuncture Points; Acupuncture Therapy; Administration, Oral; Aged; Aged, 80 and over; Combined Mod | 2015 |
[Analysis on somnipathy related factors in elderly patients with stroke and comparative study on the efficacy of treatment by traditional Chinese medicine and by estazolam].
Topics: Aged; Aged, 80 and over; Diagnosis, Differential; Drugs, Chinese Herbal; Estazolam; Female; Humans; | 2009 |
[Effect of modified xiaoyao powder for improving sleep in patients with psychological stress insomnia].
Topics: Adult; Drug Therapy, Combination; Drugs, Chinese Herbal; Estazolam; Female; Humans; Male; Middle Age | 2009 |
The XIA's No. 1 sleeping Prescription for the treatment of insomnia of the deficiency type: a clinical observation of 60 cases.
Topics: Adult; Anti-Anxiety Agents; Chi-Square Distribution; Estazolam; Female; Humans; Male; Medicine, Chin | 2009 |
A randomized, double-blind, double-dummy, multicenter, controlled trial on brotizolam intervention in outpatients with insomnia.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Anxiety Agents; Azepines; China; Double-Blind Me | 2013 |
Treatment of phlegm- and heat-induced insomnia by acupuncture in 120 cases.
Topics: Acupuncture Therapy; Adult; Aged; Anti-Anxiety Agents; Combined Modality Therapy; Diagnosis, Differe | 2003 |
[Effects of midazolam and estazolam as hypnotics in hypertensive patients with chronic insomnia: a multicentre, open labeled, randomized clinical trial].
Topics: Aged; Estazolam; Female; Humans; Hypertension; Hypnotics and Sedatives; Male; Midazolam; Middle Aged | 2006 |
[Comparative study on treatment of somnipathy in patients with hypertension by traditional Chinese medicine and by estazolam].
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Blood Pressure; Diagnosis, Differential; Drugs, Chi | 2007 |
Dose-related effects of estazolam on sleep of patients with insomnia.
Topics: Adult; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Estazolam; Female; Humans; Male; React | 1983 |
Hypnotic efficacy of estazolam compared with flurazepam in outpatients with insomnia.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Double-Blind Method; Estazolam; Female; Flurazepam; Humans | 1991 |
Estazolam treatment of insomnia in generalized anxiety disorder: a placebo-controlled study.
Topics: Adult; Aged; Anxiety Disorders; Cluster Analysis; Double-Blind Method; Estazolam; Female; Humans; Ma | 1991 |
Safety of estazolam. The United States clinical experience.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Bl | 1990 |
Efficacy of estazolam. The United States clinical experience.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Anxiety Disorders; Chronic Disease; | 1990 |
Estazolam and flurazepam: a multicenter, placebo-controlled comparative study in outpatients with insomnia.
Topics: Ambulatory Care; Anti-Anxiety Agents; Double-Blind Method; Drug Evaluation; Estazolam; Flurazepam; H | 1990 |
Comparative efficacy of estazolam, flurazepam, and placebo in outpatients with insomnia.
Topics: Adult; Aged; Ambulatory Care; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Dr | 1986 |
Estazolam in the treatment of insomnia.
Topics: Adult; Aged; Anti-Anxiety Agents; Estazolam; Female; Humans; Male; Middle Aged; Psychiatric Status R | 1986 |
11 other studies available for estazolam and Chronic Insomnia
| Article | Year |
|---|---|
[Sleep-improving mechanism of Chaiqin Ningshen Granules in insomnia rats: based on hippocampal metabonomics].
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Estazolam; Hippoca | 2022 |
Effects of electroacupuncture on the ventral tegmental area- nucleus accumbens dopamine pathway in rats with chronic sleep deprivation.
Topics: Animals; Dopamine; Electroacupuncture; Estazolam; Nucleus Accumbens; Rats; Sleep Deprivation; Sleep | 2023 |
Pearl powder reduces sleep disturbance stress response through regulating proteomics in a rat model of sleep deprivation.
Topics: Animals; Behavior, Animal; Calcium Carbonate; Chromatography, Liquid; Cognition; Disease Models, Ani | 2020 |
Dependence, misuse, and beliefs regarding use of hypnotics by elderly psychiatric patients taking zolpidem, estazolam, or flunitrazepam.
Topics: Aged; Attitude to Health; Estazolam; Female; Flunitrazepam; Humans; Hypnotics and Sedatives; Male; P | 2015 |
Clinical efficacies of treating refractory insomnia patients with estazolam plus alternating current magnetic field.
Topics: Adult; Aged; Anti-Anxiety Agents; Estazolam; Female; Humans; Magnetic Field Therapy; Male; Middle Ag | 2012 |
The effects of estazolam on sleep, performance, and memory: a long-term sleep laboratory study of elderly insomniacs.
Topics: Aged; Double-Blind Method; Drug Evaluation; Estazolam; Female; Humans; Male; Memory; Middle Aged; Ps | 1992 |
Avoiding the blanket approach to insomnia. Targeted therapy for specific causes.
Topics: Anti-Anxiety Agents; Benzodiazepines; Chronic Disease; Diagnosis, Differential; Estazolam; Flurazepa | 1991 |
Estazolam--a new benzodiazepine hypnotic.
Topics: Estazolam; Humans; Hypnotics and Sedatives; Sleep Initiation and Maintenance Disorders | 1991 |
Critical issues in the management of insomnia: investigators report on estazolam. Proceedings of a symposium. June 3, 1989, Dallas, Texas.
Topics: Anti-Anxiety Agents; Estazolam; Humans; Sleep Initiation and Maintenance Disorders | 1990 |
Chronic hypnotic efficacy of estazolam.
Topics: Adult; Anti-Anxiety Agents; Estazolam; Female; Humans; Male; Recurrence; Sleep Initiation and Mainte | 1986 |
[Controlled clinical evaluation of 2 hypnotic triazole benzodiazepines, estazolam and triazolam, used the night before surgical interventions].
Topics: Adult; Anti-Anxiety Agents; Estazolam; Female; Humans; Male; Middle Aged; Premedication; Sleep; Slee | 1987 |