eslicarbazepine acetate has been researched along with Seizures in 67 studies
*Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.49) | 18.2507 |
| 2000's | 4 (5.97) | 29.6817 |
| 2010's | 37 (55.22) | 24.3611 |
| 2020's | 25 (37.31) | 2.80 |
| Authors | Studies |
|---|---|
| Alves, PC; Benes, J; Cunha, RA; Figueiredo, AA; Freitas, AP; Garrett, J; Learmonth, DA; Parada, A; Soares-da-Silva, P | 1 |
| Costa, R; Gama, H; Magalhães, LM; Moreira, J; Soares-da-Silva, P; Vieira, M | 1 |
| Dipper-Wawra, M; Fidzinski, P; Holtkamp, M; Kraus, L; Maier, N; Monni, L; Schmitz, D; Soares-da-Silva, P | 1 |
| Gama, H; Ikedo, F; Józwiak, S; Kirkham, F; Moreira, J; Pereira, A; Veggiotti, P | 1 |
| Brigo, F; Del Giovane, C; Lattanzi, S; Russo, E; Silvestrini, M; Striano, P; Trinka, E; Zaccara, G | 1 |
| Cho, JY; Chung, JY; Hwang, I; Hwang, S; Jang, IJ; Kim, E; Lee, S; Oh, J | 1 |
| Altalib, H; Blum, D; Cantu, D; Grinnell, T; Ikedo, F; Vieira, M; Zhang, Y | 1 |
| Groppa, S; Klimpe, S; Melzer, N; Meuth, SG; Sandner, K; Vieth, TL; Winter, Y | 1 |
| DeKoven, M; Lee, I; Liu, H; Mehta, D; Wensel, B; Williams, GR | 1 |
| Aboumatar, S; Cantu, D; Grinnell, T; Krishnaiengar, SR; Zhang, Y | 1 |
| Bentes, C; Gigli, GL; Knake, S; Koepp, MJ; Magalhães, LM; Mah, YH; Moreira, J; Pereira, A; Serratosa, JM; Soares-da-Silva, P; Trinka, E; Zelano, J | 1 |
| Kim, DW; Kwack, DW | 1 |
| Cantu, D; Gama, H; Grinnell, T; Hall, D; Krishnaiengar, SR; Pereira, A | 1 |
| Cantu, D; Grinnell, T; Hall, D; Pereira, A | 1 |
| Cabeza-Alvarez, C; Campos, D; Garamendi-Ruiz, I; García, A; Giráldez, BG; López-González, FJ; Molins, A; Querol, R; Serrano, P; Serratosa, JM; Zurita, J | 1 |
| Brecht, S; Kockelmann, E; Lendemans, D; Losch, F; Weissinger, F; Winter, Y | 1 |
| Blum, D; Cantu, D; Costa, R; Grinnell, T; Józwiak, S; Li, Y; McGoldrick, PE; Mintz, M; Moreira, J; Pina-Garza, JE; Wolf, SM | 1 |
| Ben-Menachem, E; Blum, D; Gama, H; Grinnell, T; Kochen, S; Li, Y; Resnick, T; Rogin, J; Soares-da-Silva, P; Strom, L | 1 |
| Chen, D; Chu, S; Liu, L; Tan, G; Wang, HJ; Zhu, LN | 1 |
| Chaves, J; Fernandes, H; Loureiro, R; McMurray, R; Sales, F; Villanueva, V | 1 |
| Heo, YA | 1 |
| Bak, LK; Jakobsen, E; Krarup, S; Lindholm, SEH; Mertz, C; Pinborg, LH | 1 |
| Anastassopoulos, KP; Colman, S; Cramer, JA; Grinnell, T; Mehta, D; Williams, GR | 1 |
| Allard, J; Ellawela, S; Henley, W; Hudson, S; Lawthom, C; Mclean, B; Pace, A; Rajakulendran, S; Shankar, R; Tittensor, P | 1 |
| Blum, D; Cantu, D; Gama, H; Grinnell, T; Holmes, GL; Kirkham, FJ; Moreira, J; Pina-Garza, JE; Sankar, R; Tosiello, R; Wheless, J | 1 |
| Andermann, E; Ben-Menachem, E; Blum, D; Carreño, M; Cendes, F; Gama, H; Grinnell, T; Penovich, P; Ramsay, RE; Rocha, F; Rogin, J; Rosenfeld, W; Soares-da-Silva, P; Tosiello, R | 1 |
| Blum, D; Cantu, D; Gidal, B; Grinnell, T; Hixson, J; Mehta, D; Pikalov, A; Zhang, Y | 1 |
| Delanty, N; Fernandes, H; Holtkamp, M; Loureiro, R; McMurray, R; Mecarelli, O; Sales, F; Villanueva, V | 1 |
| Brodie, MJ; Stephen, LJ; Wishart, A | 1 |
| Agredano, PM; Bayarri, PG; Bermejo, PE; Campos, D; Falip, M; García-Morales, I; Gil-Nagel, A; Giráldez, BG; Gomariz, EL; González, FJL; Jiménez-Huete, A; Jovel, CE; Navacerrada, FJ; Ojeda, J; Palao, S; Pascual, MRQ; Prior, MJAA; Sáez, AA; Toledano, R | 1 |
| Cagnetti, C; Foschi, N; Lattanzi, S; Lorusso, A; Provinciali, L; Silvestrini, M | 1 |
| Costa, R; Gama, H; Graça, J; Magalhães, LM; Soares-da-Silva, P; Vieira, M | 1 |
| Bainbridge, J; Blum, D; Chudasama, V; Fiedler-Kelly, J; Ludwig, E; Marvanova, M; Phillips, L; Sunkaraneni, S | 1 |
| Delanty, N; Holtkamp, M; McMurray, R; Rodriguez-Uranga, J; Santagueda, P; Villanueva, V | 1 |
| Ben-Menachen, E; Chaves, J; Elger, C; Gama, H; Gil-Nagel, A; Koepp, M; Kowacs, PA; Moreira, J; Rocha, JF; Soares-da-Silva, P; Trinka, E; Villanueva, V | 1 |
| Biton, V; Blum, D; Cheng, H; Elger, C; Gama, H; Grinnell, T; Harvey, JH; Krauss, G; Soares da Silva, P; Trinka, E | 1 |
| Johnson, EL; Krauss, GL; Kwok, CS | 1 |
| Ahmed, A; Henley, W; Jalihal, V; McLean, BN; Parrett, M; Sander, JW; Shankar, R; Tittensor, P | 1 |
| Gama, H; Jóźwiak, S; Moreira, J; Rocha, F; Soares-da-Silva, P; Veggiotti, P | 1 |
| Ben-Menachem, E; Blum, D; Carreño, M; da Silva, PS; Gidal, BE; Grinnell, T; Li, Y; Mintzer, S; Moreira, J; Rogin, JB; Schwab, M; Wechsler, RT | 1 |
| Blum, D; Fiedler-Kelly, J; Grinnell, T; Ludwig, EA; Passarell, JA; Sunkaraneni, S | 1 |
| Andermann, E; Ben-Menachem, E; Benbadis, SR; Biraben, A; Biton, V; Blum, D; Carreño, M; Cheng, H; Gama, H; Rocha, F; Shah, AK; Shneker, B; Trinka, E | 1 |
| Assenza, F; Assenza, G; Di Lazzaro, V; Lanzone, J; Mecarelli, O; Pulitano, P; Tombini, M | 1 |
| Ben-Menachem, E; Blum, D; Carreño, M; Falcão, A; Fiedler-Kelly, J; Gidal, BE; Grinnell, T; Jacobson, MP; Ludwig, E; Moreira, J; Passarell, J; Rocha, F; Soares-da-Silva, P; Sunkaraneni, S | 1 |
| Blum, D; Fiedler-Kelly, J; Galluppi, G; Hopkins, S; Ludwig, E; Sunkaraneni, S | 1 |
| Delanty, N; Holtkamp, M; McMurray, R; Sales, F; Serratosa, J; Villanueva, V | 1 |
| Abou-Khalil, B; Blum, D; Cheng, H; Gama, H; Grinnell, T; Jung, J; Klein, P; Rocha, F; Ryvlin, P; Shah, A; Specchio, LM | 1 |
| Costa, R; Gama, H; Ikedo, F; Rocha, JF; Soares-da-Silva, P; Steinhoff, B | 1 |
| Blum, D; Cheng, H; Chung, S; Grinnell, T; Jung, J; Shah, A; Sinha, SR; Stern, JM | 1 |
| Alvarez, BM; Baiges, JJ; Bermejo, P; Bertol, V; Bonet, M; Castro-Vilanova, MD; Esteve, P; Galiano, ML; Garcés, M; Giner, P; Hampel, K; López-González, FJ; Massot-Tarrús, A; Mauri, JÁ; Montoya, J; Ojeda, J; Poza, JJ; Quiroga-Subirana, P; Rodríguez-Osorio, X; Rodriguez-Uranga, JJ; Ruiz-Giménez, J; Toledo, M; Tortosa-Conesa, D; Villanueva, V | 1 |
| Camacho, JL; Castillo, A; Flores, J; Garcés, M; Giner, P; Giráldez, BG; Guillamón, E; López González, FJ; López-Gomáriz, E; Mauri, JA; Molins, A; Palau, J; Rodríguez-Uranga, J; Salas-Puig, J; Serratosa, JM; Toledo, M; Torres, N; Villanueva, V | 1 |
| Loureiro, AI; Sierra-Marcuño, G; Sierra-Paredes, G; Soares-da-Silva, P; Wright, LC | 1 |
| Abou-Khalil, B; Biraben, A; Blum, D; Cheng, H; Galimberti, CA; Harvey, J; Hong, SB; Kowacs, PA; Nunes, T; Rogin, JB; Soares-da-Silva, P; Sperling, MR | 1 |
| Bhatia, P; Blum, D; Cheng, H; Grinnell, T; Jacobson, MP; Pazdera, L | 1 |
| Bhoi, SK; Gupta, DK; Kalita, J; Misra, UK | 1 |
| Anastassopoulos, KP; Blum, D; Bond, TC; Cramer, JA; Gilliam, FG; Moreira, J; Rocha, F; Ryvlin, P; Specchio, LM; Velez, FF; Wang, X | 1 |
| Dhillon, S; Shirley, M | 1 |
| Ben-Menachem, E; Holtkamp, M; Peltola, J; Shorvon, SD; Steinhoff, BJ; Trinka, E; Villanueva, V | 1 |
| Anastassopoulos, KP; Blum, D; Bond, TC; Cramer, JA; Sousa, R; Velez, FF; Wang, X | 1 |
| Almeida, L; Butoianu, N; Falcão, A; Magureanu, SA; Minciu, I; Nunes, T; Soares-da-Silva, P | 1 |
| Almeida, L; Gil-Nagel, A; Lopes-Lima, J; Maia, J; Soares-da-Silva, P | 1 |
| Almeida, L; Ben-Menachem, E; Gabbai, AA; Hufnagel, A; Maia, J; Soares-da-Silva, P | 1 |
| Almeida, L; Elger, C; Falcão, A; Halász, P; Perucca, E; Soares-da-Silva, P | 1 |
| Almeida, L; Falcão, A; Fuseau, E; Nunes, T; Soares-da-Silva, P | 1 |
| Mauri-Llerda, JA | 1 |
| Núñez-Rodriguez, A; Oreiro-García, T; Sierra-Marcuño, G; Sierra-Paredes, G; Vázquez-López, A | 1 |
| Oreiro-García, MT; Sierra-Marcuño, G; Sierra-Paredes, G; Vázquez-Illanes, MD | 1 |
10 review(s) available for eslicarbazepine acetate and Seizures
| Article | Year |
|---|---|
Third-Generation Antiseizure Medications for Adjunctive Treatment of Focal-Onset Seizures in Adults: A Systematic Review and Network Meta-analysis.
Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Dibenzazepines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lacosamide; Male; Middle Aged; Network Meta-Analysis; Nitriles; Pyridones; Pyrrolidinones; Randomized Controlled Trials as Topic; Seizures; Tetrazoles | 2022 |
The tolerability and safety profile of eslicarbazepine acetate in neurological disorders.
Topics: Anticonvulsants; Dibenzazepines; Dose-Response Relationship, Drug; Humans; Randomized Controlled Trials as Topic; Seizures | 2020 |
Eslicarbazepine Acetate: A Review in Focal-Onset Seizures.
Topics: Adolescent; Adult; Age Factors; Animals; Anticonvulsants; Child; Dibenzazepines; Dose-Response Relationship, Drug; Humans; Seizures; Voltage-Gated Sodium Channel Blockers | 2020 |
Safety Profile of Eslicarbazepine Acetate as Add-On Therapy in Adults with Refractory Focal-Onset Seizures: From Clinical Studies to 6 Years of Post-Marketing Experience.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Anticonvulsants; Clinical Trials, Phase III as Topic; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Europe; Female; Humans; Male; Randomized Controlled Trials as Topic; Safety; Seizures | 2017 |
Comparing Safety and Efficacy of "Third-Generation" Antiepileptic Drugs: Long-Term Extension and Post-marketing Treatment.
Topics: Acetamides; Anticonvulsants; Dibenzazepines; Drug-Related Side Effects and Adverse Reactions; Follow-Up Studies; Humans; Lacosamide; Longitudinal Studies; Medication Adherence; Nitriles; Product Surveillance, Postmarketing; Pyridones; Pyrrolidinones; Seizures | 2017 |
Psychiatric and cognitive adverse events: A pooled analysis of three phase III trials of adjunctive eslicarbazepine acetate for partial-onset seizures.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Clinical Trials, Phase III as Topic; Cognitive Dysfunction; Depression; Depressive Disorder; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Seizures; Treatment Outcome | 2018 |
Eslicarbazepine Acetate Monotherapy: A Review in Partial-Onset Seizures.
Topics: Administration, Oral; Anticonvulsants; Dibenzazepines; Epilepsies, Partial; Humans; Seizures | 2016 |
Eslicarbazepine acetate: its effectiveness as adjunctive therapy in clinical trials and open studies.
Topics: Anticonvulsants; Clinical Trials, Phase III as Topic; Dibenzazepines; Drug Substitution; Epilepsies, Partial; Humans; Randomized Controlled Trials as Topic; Seizures | 2017 |
Pharmacokinetics, drug interactions and exposure-response relationship of eslicarbazepine acetate in adult patients with partial-onset seizures: population pharmacokinetic and pharmacokinetic/pharmacodynamic analyses.
Topics: Adult; Anticonvulsants; Clinical Trials, Phase III as Topic; Dibenzazepines; Dose-Response Relationship, Drug; Drug Interactions; Humans; Seizures | 2012 |
[Eslicarbazepine acetate: a novel therapeutic alternative in the treatment of focal seizures].
Topics: Dibenzazepines; Drug Interactions; Humans; Seizures | 2012 |
27 trial(s) available for eslicarbazepine acetate and Seizures
| Article | Year |
|---|---|
Safety of Eslicarbazepine Acetate in Elderly Versus Non-Elderly Patients with Focal Seizures: From Pooled Data of Clinical Studies to 8 Years of Post-Marketing Experience.
Topics: Adult; Aged; Anticonvulsants; Dibenzazepines; Dizziness; Drug-Related Side Effects and Adverse Reactions; Humans; Hyponatremia; Marketing; Middle Aged; Seizures; Treatment Outcome | 2021 |
Long-term therapeutic effect of eslicarbazepine acetate in children: An open-label extension of a cognition study in children aged 6-16 years.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Cognition; Dibenzazepines; Double-Blind Method; Humans; Seizures; Treatment Outcome | 2022 |
The pharmacokinetic, safety, and tolerability profiles of eslicarbazepine acetate are comparable between Korean and White subjects.
Topics: Adult; Anticonvulsants; Dibenzazepines; Double-Blind Method; Humans; Republic of Korea; Seizures | 2022 |
Time to baseline seizure count in patients with focal seizures receiving adjunctive eslicarbazepine acetate in a phase IV clinical trial.
Topics: Adult; Anticonvulsants; Dibenzazepines; Double-Blind Method; Humans; Lamotrigine; Levetiracetam; Seizures; Treatment Outcome | 2023 |
Antiepileptogenesis after stroke-trials and tribulations: Methodological challenges and recruitment results of a Phase II study with eslicarbazepine acetate.
Topics: COVID-19; Humans; Ischemic Stroke; Pandemics; SARS-CoV-2; Seizures; Stroke | 2023 |
Long-term quality of life in patients with focal seizures treated with adjunctive eslicarbazepine acetate.
Topics: Anticonvulsants; Double-Blind Method; Fatigue; Humans; Quality of Life; Seizures; Treatment Outcome | 2023 |
Time to sustained responder status in patients with focal seizures treated with adjunctive eslicarbazepine acetate.
Topics: Anticonvulsants; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Seizures; Treatment Outcome | 2023 |
Safety and Tolerability of Adjunctive Eslicarbazepine Acetate in Pediatric Patients (Aged 4-17 Years) With Focal Seizures.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Dibenzazepines; Double-Blind Method; Europe; Female; Humans; Male; Seizures; Treatment Outcome | 2020 |
Analysis of cutaneous allergic reactions in clinical trials of eslicarbazepine acetate.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Dibenzazepines; Double-Blind Method; Drug Eruptions; Exanthema; Female; Humans; Incidence; Male; Oral Ulcer; Pruritus; Seizures | 2020 |
Associations between seizure severity change and patient characteristics, changes in seizure frequency, and health-related quality of life in patients with focal seizures treated with adjunctive eslicarbazepine acetate: Post hoc analyses of clinical trial
Topics: Anticonvulsants; Dibenzazepines; Double-Blind Method; Humans; Quality of Life; Seizures; Treatment Outcome | 2020 |
Long-term safety and tolerability of adjunctive eslicarbazepine acetate in children with focal seizures.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Dibenzazepines; Double-Blind Method; Humans; Seizures; Treatment Outcome | 2020 |
Efficacy and safety of eslicarbazepine acetate as a first or later adjunctive therapy in patients with focal seizures.
Topics: Anticonvulsants; Dibenzazepines; Double-Blind Method; Humans; Lamotrigine; Levetiracetam; Quality of Life; Seizures; Treatment Outcome | 2021 |
Influence of titration schedule and maintenance dose on the tolerability of adjunctive eslicarbazepine acetate: An integrated analysis of three randomized placebo-controlled trials.
Topics: Adult; Anticonvulsants; Chemotherapy, Adjuvant; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Resistant Epilepsy; Female; Humans; Male; Medication Adherence; Seizures; Treatment Outcome | 2018 |
Effects of adjunctive eslicarbazepine acetate on neurocognitive functioning in children with refractory focal-onset seizures.
Topics: Adolescent; Anticonvulsants; Attention; Child; Cognition; Combined Modality Therapy; Dibenzazepines; Double-Blind Method; Epilepsy; Female; Humans; Male; Memory; Quality of Life; Seizures; Treatment Outcome | 2018 |
Effects of adjunctive eslicarbazepine acetate on serum lipids in patients with partial-onset seizures: Impact of concomitant statins and enzyme-inducing antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Induction; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Middle Aged; Seizures; Treatment Outcome; Young Adult | 2018 |
Population Pharmacokinetics and Exposure-Response Analyses of Eslicarbazepine Acetate Efficacy and Safety in Monotherapy of Partial-Onset Seizures.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticonvulsants; Dibenzazepines; Dizziness; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Headache; Healthy Volunteers; Humans; Hyponatremia; Male; Middle Aged; Models, Biological; Nausea; Seizures; Sodium; Treatment Outcome | 2018 |
Exposure-safety and efficacy response relationships and population pharmacokinetics of eslicarbazepine acetate.
Topics: Adult; Aged; Anticonvulsants; Dibenzazepines; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Seizures | 2018 |
Tolerability of adjunctive eslicarbazepine acetate according to concomitant lamotrigine or carbamazepine use: A subgroup analysis of three phase III trials in adults with focal (partial-onset) seizures.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Dibenzazepines; Diplopia; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Randomized Controlled Trials as Topic; Seizures; Vomiting; Young Adult | 2018 |
Safety, Tolerability and Efficacy of Eslicarbazepine Acetate as Adjunctive Therapy in Patients Aged ≥ 65 Years with Focal Seizures.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Dibenzazepines; Female; Humans; Male; Quality of Life; Seizures; Treatment Outcome | 2018 |
Long-term safety and efficacy following conversion to eslicarbazepine acetate monotherapy in adults with focal seizures.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Depression; Dibenzazepines; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Longitudinal Studies; Male; Middle Aged; Quality of Life; Seizures; Treatment Outcome; Young Adult | 2019 |
Eslicarbazepine acetate as adjunctive therapy in patients with uncontrolled partial-onset seizures: Results of a phase III, double-blind, randomized, placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Seizures; Treatment Outcome; Young Adult | 2015 |
Efficacy and safety of conversion to monotherapy with eslicarbazepine acetate in adults with uncontrolled partial-onset seizures: a historical-control phase III study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Dibenzazepines; Double-Blind Method; Epilepsies, Partial; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Seizures; Treatment Outcome; Young Adult | 2015 |
Severity and burden of partial-onset seizures in a phase III trial of eslicarbazepine acetate.
Topics: Adult; Aged; Anticonvulsants; Cost of Illness; Dibenzazepines; Double-Blind Method; Epilepsies, Partial; Female; Follow-Up Studies; Humans; Male; Middle Aged; Seizures; Severity of Illness Index; Surveys and Questionnaires | 2015 |
Impact of seizure frequency reduction on health-related quality of life among clinical trial subjects with refractory partial-onset seizures: A pooled analysis of phase III clinical trials of eslicarbazepine acetate.
Topics: Adult; Anticonvulsants; Dibenzazepines; Double-Blind Method; Epilepsies, Partial; Female; Humans; Male; Mental Health; Middle Aged; Quality of Life; Seizures; Treatment Outcome | 2017 |
Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Anticonvulsants; Dibenzazepines; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsies, Partial; Female; Headache; Humans; Male; Middle Aged; Nausea; Patient Selection; Placebos; Seizures; Treatment Outcome | 2009 |
Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy.
Topics: Adult; Anticonvulsants; Dibenzazepines; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Synergism; Epilepsies, Partial; Female; Headache; Humans; Male; Middle Aged; Nausea; Seizures; Treatment Outcome | 2010 |
Pharmacokinetics of eslicarbazepine acetate at steady-state in adults with partial-onset seizures.
Topics: Adult; Anticonvulsants; Carbamazepine; Dibenzazepines; Dose-Response Relationship, Drug; Female; Humans; International Cooperation; Male; Middle Aged; Oxcarbazepine; Seizures; Tandem Mass Spectrometry; Time Factors; Young Adult | 2011 |
30 other study(ies) available for eslicarbazepine acetate and Seizures
| Article | Year |
|---|---|
Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives.
Topics: Amides; Animals; Anticonvulsants; Azepines; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Electroshock; In Vitro Techniques; Ion Channel Gating; Motor Activity; Prodrugs; Rats; Seizures; Sodium; Stereoisomerism; Structure-Activity Relationship; Synaptosomes | 1999 |
In vitro and in vivo anti-epileptic efficacy of eslicarbazepine acetate in a mouse model of KCNQ2-related self-limited epilepsy.
Topics: Animals; Anticonvulsants; Dibenzazepines; Epilepsy; Epilepsy, Temporal Lobe; KCNQ2 Potassium Channel; Mice; Seizures | 2022 |
Psychiatric adverse events in three phase III trials of eslicarbazepine acetate for focal seizures.
Topics: Adult; Anticonvulsants; Dibenzazepines; Humans; Seizures; Treatment Outcome | 2022 |
Eslicarbazepine Acetate as Adjunctive Therapy for Primary Generalized Tonic-Clonic Seizures in Adults: A Prospective Observational Study.
Topics: Adult; Anticonvulsants; Dibenzazepines; Drug-Related Side Effects and Adverse Reactions; Epilepsies, Myoclonic; Humans; Prospective Studies; Seizures; Sodium Channel Blockers; Treatment Outcome | 2022 |
Comparative economic outcomes in patients with focal seizures initiating eslicarbazepine acetate versus brivaracetam in the long-term care setting in the USA.
Topics: Anticonvulsants; Humans; Long-Term Care; Retrospective Studies; Seizures; Treatment Outcome | 2022 |
Potential efficacy and safety of eslicarbazepine acetate oral loading in patients with epilepsy.
Topics: Adult; Anticonvulsants; Dibenzazepines; Epilepsy; Humans; Seizures; Treatment Outcome | 2023 |
Clinical outcomes of eslicarbazepine acetate monotherapy for focal-onset seizures: A multicenter audit.
Topics: Adult; Aged; Anticonvulsants; Dibenzazepines; Female; Humans; Male; Middle Aged; Retrospective Studies; Seizures; Treatment Outcome; Young Adult | 2019 |
Effectiveness of eslicarbazepine acetate in dependency of baseline anticonvulsant therapy: Results from a German prospective multicenter clinical practice study.
Topics: Adult; Aged; Anticonvulsants; Dibenzazepines; Drug Resistant Epilepsy; Female; Humans; Male; Middle Aged; Prospective Studies; Seizures; Sodium Channel Blockers; Young Adult | 2019 |
Eslicarbazepine acetate in post-stroke epilepsy: Clinical practice evidence from Euro-Esli.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Dibenzazepines; Epilepsy; Female; Humans; Male; Middle Aged; Seizures; Stroke; Treatment Outcome; Young Adult | 2020 |
Distinct effects on cAMP signaling of carbamazepine and its structural derivatives do not correlate with their clinical efficacy in epilepsy.
Topics: Adenylyl Cyclases; Anticonvulsants; Calcium Signaling; Carbamazepine; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dibenzazepines; Epilepsy; HEK293 Cells; Humans; Oxcarbazepine; Seizures; Signal Transduction; Treatment Outcome | 2020 |
Eslicarbazepine acetate response in intellectual disability population versus general population.
Topics: Adult; Anticonvulsants; Dibenzazepines; Epilepsy; Female; Humans; Intellectual Disability; Male; Middle Aged; Prevalence; Retrospective Studies; Seizures | 2021 |
Comparative analysis of the safety and tolerability of eslicarbazepine acetate in older (≥60 years) and younger (18-59 years) adults.
Topics: Adolescent; Adult; Anticonvulsants; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Middle Aged; Nausea; Seizures; Sleepiness; Treatment Outcome; Vertigo; Vomiting; Young Adult | 2021 |
Predictors of seizure freedom, response and retention after 12 months of treatment with eslicarbazepine acetate: A post-hoc analysis of the Euro-Esli study.
Topics: Adult; Anticonvulsants; Dibenzazepines; Freedom; Humans; Seizures; Treatment Outcome | 2021 |
Psychiatric side effects and antiepileptic drugs: Observations from prospective audits.
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Dibenzazepines; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Female; Fructose; Humans; Lacosamide; Levetiracetam; Male; Medical Audit; Mental Disorders; Middle Aged; Nitriles; Piracetam; Pregabalin; Prospective Studies; Pyridones; Retrospective Studies; Seizures; Sodium Channel Blockers; Topiramate; Young Adult | 2017 |
Efficacy and safety of eslicarbazepine acetate monotherapy for partial-onset seizures: Experience from a multicenter, observational study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Child; Depression; Dibenzazepines; Dizziness; Female; Headache; Humans; Male; Middle Aged; Prospective Studies; Seizures; Spain; Treatment Outcome; Young Adult | 2017 |
Eslicarbazepine acetate as adjunctive treatment in partial-onset epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Dibenzazepines; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Oxcarbazepine; Retrospective Studies; Seizures; Young Adult | 2018 |
Population Pharmacokinetic Evaluation and Missed-Dose Simulations for Eslicarbazepine Acetate Monotherapy in Patients With Partial-Onset Seizures.
Topics: Adult; Anticonvulsants; Computer Simulation; Dibenzazepines; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Female; Humans; Male; Middle Aged; Seizures; Time Factors | 2018 |
Euro-Esli: a European audit of real-world use of eslicarbazepine acetate as a treatment for partial-onset seizures.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Clinical Trials as Topic; Dibenzazepines; Dose-Response Relationship, Drug; Europe; Female; Follow-Up Studies; Humans; Male; Middle Aged; Seizures; Treatment Outcome; Young Adult | 2017 |
Pooled efficacy and safety of eslicarbazepine acetate as add-on treatment in patients with focal-onset seizures: Data from four double-blind placebo-controlled pivotal phase III clinical studies.
Topics: Adolescent; Adult; Anticonvulsants; Clinical Trials as Topic; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Seizures; Treatment Outcome; Young Adult | 2017 |
Eslicarbazepine acetate as a replacement for levetiracetam in people with epilepsy developing behavioral adverse events.
Topics: Adult; Anticonvulsants; Dibenzazepines; Drug Substitution; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Female; Humans; Levetiracetam; Male; Mental Disorders; Middle Aged; Psychiatric Status Rating Scales; Retrospective Studies; Seizures; Substance Withdrawal Syndrome; Treatment Outcome; Voltage-Gated Sodium Channel Blockers | 2018 |
The ROME (Retrospective Observational Multicenter study on Eslicarbazepine) study: Efficacy and behavioural effects of Eslicarbazepine acetate as adjunctive therapy for adults with partial onset seizures in real life.
Topics: Anticonvulsants; Antidepressive Agents; Depression; Dibenzazepines; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quality of Life; Retrospective Studies; Seizures; Sleep; Treatment Outcome; Wakefulness-Promoting Agents | 2018 |
Modeling and simulations to support dose selection for eslicarbazepine acetate therapy in pediatric patients with partial-onset seizures.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Dibenzazepines; Dose-Response Relationship, Drug; Female; Humans; Levetiracetam; Male; Phenobarbital; Seizures | 2018 |
Eslicarbazepine acetate as monotherapy in clinical practice: Outcomes from Euro-Esli.
Topics: Adult; Anticonvulsants; Ataxia; Dibenzazepines; Dizziness; Europe; Fatigue; Female; Humans; Male; Middle Aged; Seizures; Sleepiness; Vertigo | 2019 |
MONOZEB: Long-term observational study of eslicarbazepine acetate monotherapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Dibenzazepines; Dizziness; Epilepsy; Female; Humans; Hyponatremia; Longitudinal Studies; Male; Middle Aged; Retrospective Studies; Seizures; Sleepiness; Young Adult | 2019 |
Long-term safety and efficacy of eslicarbazepine acetate in patients with focal seizures: results of the 1-year ESLIBASE retrospective study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Dibenzazepines; Female; Humans; Longitudinal Studies; Male; Middle Aged; Retrospective Studies; Seizures; Statistics, Nonparametric; Time Factors; Voltage-Gated Sodium Channel Blockers; Young Adult | 2014 |
Effects of eslicarbazepine acetate on acute and chronic latrunculin A-induced seizures and extracellular amino acid levels in the mouse hippocampus.
Topics: Acute Disease; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Bridged Bicyclo Compounds, Heterocyclic; Chronic Disease; Dibenzazepines; Disease Models, Animal; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Mice; Seizures; Taurine; Thiazolidines | 2014 |
Hyponatremia following esclicarbazepine therapy.
Topics: Age Factors; Anticonvulsants; Comorbidity; Dibenzazepines; Dose-Response Relationship, Drug; Drug Evaluation; Female; Follow-Up Studies; Humans; Hyponatremia; Incidence; Male; Middle Aged; Seizures; Sodium; Stroke; Voltage-Gated Sodium Channel Blockers | 2015 |
Pharmacokinetics, efficacy, and tolerability of eslicarbazepine acetate in children and adolescents with epilepsy.
Topics: Adolescent; Anticonvulsants; Area Under Curve; Child; Child, Preschool; Dibenzazepines; Drug Resistance; Epilepsy; Female; Half-Life; Humans; Male; Seizures | 2008 |
Anticonvulsant effect of eslicarbazepine acetate (BIA 2-093) on seizures induced by microperfusion of picrotoxin in the hippocampus of freely moving rats.
Topics: Administration, Oral; Animals; Anticonvulsants; Behavior, Animal; Dibenzazepines; Disease Models, Animal; Electroencephalography; Hippocampus; Male; Picrotoxin; Rats; Rats, Sprague-Dawley; Seizures | 2006 |
Effect of eslicarbazepine acetate (BIA 2-093) on latrunculin A-induced seizures and extracellular amino acid concentrations in the rat hippocampus.
Topics: Amino Acids; Animals; Anticonvulsants; Brain Chemistry; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Dibenzazepines; Electroencephalography; Extracellular Space; Hippocampus; Indicators and Reagents; Male; Marine Toxins; Microdialysis; Rats; Rats, Sprague-Dawley; Seizures; Thiazolidines | 2007 |