esculetin has been researched along with ST-Elevation-Myocardial-Infarction* in 1 studies
1 other study(ies) available for esculetin and ST-Elevation-Myocardial-Infarction
| Article | Year |
|---|---|
Mitochondria-targeted esculetin inhibits PAI-1 levels by modulating STAT3 activation and miR-19b via SIRT3: Role in acute coronary artery syndrome.
In this study we explored the microRNAs responsible for the regulation of PAI-1 during LPS-stimulated inflammation in human aortic endothelial cells and subsequently studied the effect of a newly synthesized mitochondria-targeted esculetin (Mito-Esc) that was shown for its anti-atherosclerotic potential, in modulating PAI-1 levels and its targeted miRs during angiotensin-II-induced atherosclerosis in ApoE Topics: Acute Coronary Syndrome; Animals; Anti-Inflammatory Agents; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Endothelial Cells; Humans; Lipopolysaccharides; Male; Mice, Knockout; MicroRNAs; Mitochondria; Plasminogen Activator Inhibitor 1; Signal Transduction; Sirtuin 3; ST Elevation Myocardial Infarction; STAT3 Transcription Factor; Time Factors; Transfection; Umbelliferones | 2018 |