Page last updated: 2024-10-26

erythrosine and Retinopathy of Prematurity

erythrosine has been researched along with Retinopathy of Prematurity in 22 studies

Fluoresceins: A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.

Retinopathy of Prematurity: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Thalidomide is a well-known anti-angiogenic drug."5.35The effect of thalidomide on neovascularization in a mouse model of retinopathy of prematurity. ( Katz, G; Pri-Chen, S; Rabinowitz, R; Rosner, M; Spierer, A, 2008)
"Animals that received ibuprofen during hyperoxia exposure had a significantly lower median (25th, 75th quartile) retinopathy score of 6 (5, 7."3.72Ibuprofen improves oxygen-induced retinopathy in a mouse model. ( Barr, SM; Geng, Y; Higgins, RD; Sharma, J; Yun, Y, 2003)
"Retinal neovascularization was observed by fluorescence angiography and was quantified by counting the endothelial nuclei protruding into the vitreous cavity after hematoxylin-eosin staining."1.37Netrin-1 overexpression in oxygen-induced retinopathy correlates with breakdown of the blood-retina barrier and retinal neovascularization. ( Jiang, J; Liu, D; Liu, JL; Tian, XF; Xia, XB; Xiong, SQ, 2011)
"Retinal neovascularization was evaluated by angiography with injection of fluorescein-dextran and quantification of neovascular proliferative retinopathy after 5 days in room air."1.35Suppression of retinal neovascularization by small-interference RNA targeting erythropoietin. ( Jiang, J; Xia, XB; Xiong, SQ; Xu, HZ, 2009)
"Thalidomide is a well-known anti-angiogenic drug."1.35The effect of thalidomide on neovascularization in a mouse model of retinopathy of prematurity. ( Katz, G; Pri-Chen, S; Rabinowitz, R; Rosner, M; Spierer, A, 2008)
"Riluzole is a Food and Drug Administration-approved anti-ALS drug with a favorable adverse effect profile."1.34Insulin increases retinal hemorrhage in mild oxygen-induced retinopathy in the rat: inhibition by riluzole. ( Cho, KS; Chung, H; Koh, JY; Yoo, MH; Yoon, YH, 2007)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.09)18.7374
1990's3 (13.64)18.2507
2000's8 (36.36)29.6817
2010's8 (36.36)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Gonzalez, A1
Agarwal-Sinha, S1
Chen, X1
Mangalesh, S1
Tran-Viet, D1
Freedman, SF1
Vajzovic, L1
Toth, CA1
Blair, MP1
Hilkert Rodriguez, S1
Chan, RVP1
Shapiro, MJ1
Lepore, D1
Ji, MH1
Quinn, G1
Bai, YJ1
Huang, LZ1
Zhou, AY1
Zhao, M1
Yu, WZ1
Li, XX1
Dal Monte, M1
Ristori, C1
Cammalleri, M1
Bagnoli, P1
Xiong, SQ2
Xia, XB2
Xu, HZ1
Jiang, J2
Tian, XF1
Liu, D1
Liu, JL1
Newman, H1
Shapira, S1
Spierer, O1
Kraus, S1
Rosner, M3
Pri-Chen, S3
Loewenstein, A1
Arber, N1
Barak, A1
Rabinowitz, R2
Priel, A1
Spierer, A2
Zhang, HB1
Sun, NX1
Liang, HC1
Xiao, XH1
Liu, XN1
Wang, YN1
Sharma, J1
Barr, SM1
Geng, Y1
Yun, Y1
Higgins, RD3
Yoo, MH1
Yoon, YH1
Chung, H1
Cho, KS1
Koh, JY1
Katz, G1
Smith, LE2
Wesolowski, E2
McLellan, A1
Kostyk, SK1
D'Amato, R1
Sullivan, R1
D'Amore, PA1
Penn, JS1
Tolman, BL1
Bullard, LE1
Yossuck, P2
Yan, Y2
Tadesse, M2
Lonchampt, M1
Pennel, L1
Duhault, J1
O'Grady, GE2
Flynn, JT2
Herrera, JA2
Cantolino, SJ1
Israel, C1
Justice, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care (BabySTEPS)[NCT02887157]191 participants (Actual)Observational2016-07-22Completed
Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care 2 and School Age Follow on Study (BabySTEPS2)[NCT04995341]236 participants (Anticipated)Interventional2021-08-16Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

22 other studies available for erythrosine and Retinopathy of Prematurity

ArticleYear
Fluorescein angiographic features post-intravitreal bevacizumab for retinopathy of prematurity: can they support rescue laser photocoagulation to the avascular retina.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2020, Volume: 55, Issue:5

    Topics: Angiogenesis Inhibitors; Bevacizumab; Child, Preschool; Fluorescein Angiography; Fluoresceins; Gesta

2020
Fluorescein Angiographic Characteristics of Macular Edema During Infancy.
    JAMA ophthalmology, 2018, 05-01, Volume: 136, Issue:5

    Topics: Birth Weight; Blood-Retinal Barrier; Capillary Permeability; Child, Preschool; Cross-Sectional Studi

2018
Fluorescein Angiographic Characteristics of Macular Edema During Infancy.
    JAMA ophthalmology, 2018, 05-01, Volume: 136, Issue:5

    Topics: Birth Weight; Blood-Retinal Barrier; Capillary Permeability; Child, Preschool; Cross-Sectional Studi

2018
Fluorescein Angiographic Characteristics of Macular Edema During Infancy.
    JAMA ophthalmology, 2018, 05-01, Volume: 136, Issue:5

    Topics: Birth Weight; Blood-Retinal Barrier; Capillary Permeability; Child, Preschool; Cross-Sectional Studi

2018
Fluorescein Angiographic Characteristics of Macular Edema During Infancy.
    JAMA ophthalmology, 2018, 05-01, Volume: 136, Issue:5

    Topics: Birth Weight; Blood-Retinal Barrier; Capillary Permeability; Child, Preschool; Cross-Sectional Studi

2018
Re: Lepore et al.: Follow-up to age 4 years of treatment of type 1 retinopathy of prematurity intravitreal bevacizumab injection versus laser: fluorescein angiographic findings (Ophthalmology. 2018;125:218-226).
    Ophthalmology, 2018, Volume: 125, Issue:10

    Topics: Bevacizumab; Fluoresceins; Follow-Up Studies; Humans; Infant, Newborn; Intravitreal Injections; Reti

2018
Reply.
    Ophthalmology, 2018, Volume: 125, Issue:10

    Topics: Bevacizumab; Fluoresceins; Follow-Up Studies; Humans; Infant, Newborn; Intravitreal Injections; Reti

2018
Antiangiogenesis effects of endostatin in retinal neovascularization.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2013, Volume: 29, Issue:7

    Topics: Angiogenesis Inhibitors; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Cell Movement; Cel

2013
Effects of somatostatin analogues on retinal angiogenesis in a mouse model of oxygen-induced retinopathy: involvement of the somatostatin receptor subtype 2.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:8

    Topics: Animals; Animals, Newborn; Blotting, Western; Dextrans; Enzyme-Linked Immunosorbent Assay; Female; F

2009
Suppression of retinal neovascularization by small-interference RNA targeting erythropoietin.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2009, Volume: 223, Issue:5

    Topics: Animals; Animals, Newborn; Base Sequence; Blotting, Western; Cell Culture Techniques; Dextrans; Dise

2009
Netrin-1 overexpression in oxygen-induced retinopathy correlates with breakdown of the blood-retina barrier and retinal neovascularization.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2011, Volume: 226, Issue:2

    Topics: Animals; Blood-Retinal Barrier; Blotting, Western; Capillary Permeability; Dextrans; Disease Models,

2011
Involvement of CD24 in angiogenesis in a mouse model of oxygen-induced retinopathy.
    Current eye research, 2012, Volume: 37, Issue:6

    Topics: Animals; Animals, Newborn; CD24 Antigen; Dextrans; Disease Models, Animal; Fluoresceins; Humans; Hyp

2012
Avastin treatment reduces retinal neovascularization in a mouse model of retinopathy of prematurity.
    Current eye research, 2012, Volume: 37, Issue:7

    Topics: Angiogenesis Inhibitors; Animals; Animals, Newborn; Antibodies, Monoclonal, Humanized; Bevacizumab;

2012
17-Alpha-estradiol ameliorating oxygen-induced retinopathy in a murine model.
    Japanese journal of ophthalmology, 2012, Volume: 56, Issue:4

    Topics: Animals; Animals, Newborn; Capillary Permeability; Dextrans; Disease Models, Animal; Dose-Response R

2012
Ibuprofen improves oxygen-induced retinopathy in a mouse model.
    Current eye research, 2003, Volume: 27, Issue:5

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Dextrans; Disease Models, Animal

2003
Insulin increases retinal hemorrhage in mild oxygen-induced retinopathy in the rat: inhibition by riluzole.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:12

    Topics: Animals; Animals, Newborn; Blotting, Western; Dextrans; Disease Models, Animal; Enzyme-Linked Immuno

2007
The effect of thalidomide on neovascularization in a mouse model of retinopathy of prematurity.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2008, Volume: 246, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Animals, Newborn; Dextrans; Disease Models, Animal; Fluoresceins;

2008
Oxygen-induced retinopathy in the mouse.
    Investigative ophthalmology & visual science, 1994, Volume: 35, Issue:1

    Topics: Animals; Dextrans; Disease Models, Animal; Fluorescein Angiography; Fluoresceins; Fundus Oculi; Glia

1994
Effect of light on oxygen-induced retinopathy in the mouse.
    Investigative ophthalmology & visual science, 1994, Volume: 35, Issue:1

    Topics: Animals; Dark Adaptation; Dextrans; Disease Models, Animal; Fluorescein Angiography; Fluoresceins; F

1994
Effect of a water-soluble vitamin E analog, trolox C, on retinal vascular development in an animal model of retinopathy of prematurity.
    Free radical biology & medicine, 1997, Volume: 22, Issue:6

    Topics: Animals; Animals, Newborn; Antioxidants; Capillaries; Chromans; Dextrans; Disease Models, Animal; Fl

1997
Dexamethasone and critical effect of timing on retinopathy.
    Investigative ophthalmology & visual science, 2000, Volume: 41, Issue:10

    Topics: Animals; Animals, Newborn; Dexamethasone; Dextrans; Disease Models, Animal; Fluoresceins; Glucocorti

2000
Hyperoxia/normoxia-driven retinal angiogenesis in mice: a role for angiotensin II.
    Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals;

2001
Lack of effect of gender on retinopathy in the mouse.
    Clinical & experimental ophthalmology, 2001, Volume: 29, Issue:5

    Topics: Animals; Animals, Newborn; Dextrans; Disease Models, Animal; Female; Fluoresceins; Humans; Hyperoxia

2001
The clinical course of retrolental fibroplasia in premature infants.
    Southern medical journal, 1972, Volume: 65, Issue:6

    Topics: Cryosurgery; Fluoresceins; Fundus Oculi; Humans; Infant, Newborn; Oxygen Inhalation Therapy; Photogr

1972
Ophthalmoscopic monitoring of oxygen therapy in premature infants. Fluorescein angiography in acute retrolental fibroplasia.
    American journal of ophthalmology, 1971, Volume: 72, Issue:2

    Topics: Acute Disease; Female; Fluoresceins; Fundus Oculi; Humans; Infant; Infant, Newborn; Male; Ophthalmos

1971