Page last updated: 2024-10-26

erythrosine and Osteoarthritis

erythrosine has been researched along with Osteoarthritis in 9 studies

Fluoresceins: A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.

Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

Research Excerpts

ExcerptRelevanceReference
"Although, several effects of glucosamine and its sulfated form (sulfated glucosamine) have been proposed for the suppression of osteoarthritis, their exact mechanisms have not been completely elucidated."3.74Sulfated glucosamine inhibits oxidation of biomolecules in cells via a mechanism involving intracellular free radical scavenging. ( Kim, MM; Kim, SK; Mendis, E; Rajapakse, N, 2008)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Gao, L1
Wang, X1
Xiong, J1
Ma, Y1
Lin, AH1
Zitnay, JL1
Li, Y1
Yu, SM1
Weiss, JA1
Sato, M1
Uchida, K1
Nakajima, H1
Miyazaki, T1
Guerrero, AR1
Watanabe, S1
Roberts, S1
Baba, H1
Shah, R1
Raska, K1
Tiku, ML1
Mendis, E1
Kim, MM1
Rajapakse, N1
Kim, SK1
Takács-Buia, L1
Iordachel, C1
Efimov, N1
Caloianu, M1
Montreuil, J1
Bratosin, D1
Singh, I1
Francis, GE1
Schünke, M1
Tillmann, B1
Brück, M1
Müller-Ruchholtz, W1
Itokazu, M1
Tanaka, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase I Single Center Open Study to Assess the Safety and Efficacy of Intra-articular Mesenchymal Stem Cells in the Treatment of Knee Osteoarthritis and Chondral Defects of the Knee[NCT03477942]Phase 116 participants (Anticipated)Interventional2018-10-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for erythrosine and Osteoarthritis

ArticleYear
Circular RNA from phosphodiesterase 4D can attenuate chondrocyte apoptosis and matrix degradation under OA milieu induced by IL-1β via circPDE4D/miR-4306/SOX9 Cascade.
    Immunopharmacology and immunotoxicology, 2022, Volume: 44, Issue:5

    Topics: Annexin A5; Apoptosis; bcl-2-Associated X Protein; Biotin; Caspase 3; Chondrocytes; Collagen Type II

2022
Microplate assay for denatured collagen using collagen hybridizing peptides.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2019, Volume: 37, Issue:2

    Topics: Animals; Cartilage; Collagen; Fluoresceins; Guinea Pigs; High-Throughput Screening Assays; Osteoarth

2019
Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis.
    Arthritis research & therapy, 2012, Feb-07, Volume: 14, Issue:1

    Topics: Animals; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen Type II;

2012
The presence of molecular markers of in vivo lipid peroxidation in osteoarthritic cartilage: a pathogenic role in osteoarthritis.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:9

    Topics: Adult; Aged; Aldehydes; Antibodies, Monoclonal; Biomarkers; Calcimycin; Cartilage, Articular; Cells,

2005
Sulfated glucosamine inhibits oxidation of biomolecules in cells via a mechanism involving intracellular free radical scavenging.
    European journal of pharmacology, 2008, Jan-28, Volume: 579, Issue:1-3

    Topics: Animals; Cells, Cultured; Chondrocytes; Dose-Response Relationship, Drug; Electron Spin Resonance Sp

2008
Pathogenesis of osteoarthritis: chondrocyte replicative senescence or apoptosis?
    Cytometry. Part B, Clinical cytometry, 2008, Volume: 74, Issue:6

    Topics: Animals; Annexin A5; Apoptosis; beta-Galactosidase; Biomarkers; Caspase 3; Cell Shape; Cell Survival

2008
A direct binding assay for rheumatoid factor serum antiglobulins using fluorescein-labelled Fc fragment of human immunoglobulin-G.
    Journal of clinical pathology, 1978, Volume: 31, Issue:10

    Topics: Adult; Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Binding Sites, Antibody; Detergents; Fluor

1978
Lectin-binding in normal and osteoarthrotic articular cartilage from STR/1N-mouse knee joints.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1988, Volume: 54, Issue:6

    Topics: Animals; Cartilage, Articular; Disease Models, Animal; Fluorescein-5-isothiocyanate; Fluoresceins; F

1988
[Localization of carbohydrate component in human synovial lining cells with fluorescent lectins and enzyme digestion].
    Nihon Seikeigeka Gakkai zasshi, 1985, Volume: 59, Issue:12

    Topics: Arthritis, Rheumatoid; Carbohydrates; Femoral Neck Fractures; Femur Head Necrosis; Fluoresceins; Hum

1985