erythrosine has been researched along with Brain Injuries in 86 studies
Fluoresceins: A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study has examined the anticonvulsant and neuroprotective effect of group II metabotropic glutamate receptor (mGluR) agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate (2R,4R-APDC) in the model of seizures induced in immature 12-day-old rats by bilateral intracerebroventricular infusion of dl-homocysteic acid (DL-HCA, 600 nmol/side)." | 7.73 | Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate. ( Druga, R; Folbergrová, J; Haugvicová, R; Kubová, H; Mares, P; Otáhal, J, 2005) |
| "The present study has examined the anticonvulsant and neuroprotective effect of group II metabotropic glutamate receptor (mGluR) agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate (2R,4R-APDC) in the model of seizures induced in immature 12-day-old rats by bilateral intracerebroventricular infusion of dl-homocysteic acid (DL-HCA, 600 nmol/side)." | 3.73 | Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate. ( Druga, R; Folbergrová, J; Haugvicová, R; Kubová, H; Mares, P; Otáhal, J, 2005) |
| "Thus, reactive gliosis and a significant increase in the expression of caspase-9 were found in the aforementioned brain area." | 1.46 | Subacute Fluoxetine Reduces Signs of Hippocampal Damage Induced by a Single Convulsant Dose of 4-Aminopyridine in Rats. ( de la Rosa, RF; Delgado, M; García-García, L; Pozo, MA; Shiha, AA, 2017) |
| "Spontaneous intracerebral hemorrhage (ICH) is a stroke subtype with no effective treatment." | 1.43 | The Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid (SAHA) Confers Acute Neuroprotection After Intracerebral Hemorrhage in Mice. ( Alleyne, CH; Dhandapani, KM; Sukumari-Ramesh, S, 2016) |
| "Following intracerebral hemorrhage (ICH), red blood cells release massive amounts of toxic heme that causes local brain injury." | 1.43 | Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage. ( Day, JP; Doré, S; Ma, B; Phillips, H; Slootsky, B; Tolosano, E, 2016) |
| "We found that single mTBI causes a brief loss of consciousness and a transient reduction in dendritic spines, reflecting a loss of excitatory synapses." | 1.43 | Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma. ( Alikhani, AD; Barton, DJ; Burns, MP; Chellappa, D; Neustadtl, A; Noël, A; Parsadanian, M; Planel, E; Villapol, S; Wilkins, TE; Winston, CN; Zapple, DN, 2016) |
| "Primary spontaneous intracerebral hemorrhage (ICH) with secondary intraventricular hemorrhage (IVH) is an important clinical problem of which little is known." | 1.42 | Chronic hydrocephalus and perihematomal tissue injury developed in a rat model of intracerebral hemorrhage with ventricular extension. ( Chen, Q; Chen, Z; Feng, H; Guo, J; Li, L; Tang, J; Tao, Y; Zhang, J, 2015) |
| "Spatial learning and memory deficits were evaluated by radial arm maze (n=8 each group) up to 21 days post-TBI." | 1.38 | Neuronal damage and functional deficits are ameliorated by inhibition of aquaporin and HIF1α after traumatic brain injury (TBI). ( Ding, JY; Ding, Y; Fredrickson, V; Guthikonda, M; Kassem, H; Kreipke, CW; Peng, C; Rafols, JA; Schafer, S; Shenaq, M, 2012) |
| "Spontaneous seizures were detected with video-electroencephalography monitoring and a lowered seizure threshold was determined based on a pentylenetetrazol (PTZ) test." | 1.36 | Association of the severity of cortical damage with the occurrence of spontaneous seizures and hyperexcitability in an animal model of posttraumatic epilepsy. ( Kharatishvili, I; Pitkänen, A, 2010) |
| " The reduction in acetyl-histone H3 immunostaining was attenuated by each of the DMA-PB dosage treatment groups." | 1.35 | HDAC inhibitor increases histone H3 acetylation and reduces microglia inflammatory response following traumatic brain injury in rats. ( Gurkoff, GG; Kozikowski, AP; Lyeth, BG; Van, KC; West, EJ; Zhang, B; Zhang, XM; Zhou, J, 2008) |
| "Dicyclomine treatment produced decreases of 38% (p = 0." | 1.35 | Dicyclomine, an M1 muscarinic antagonist, reduces biomarker levels, but not neuronal degeneration, in fluid percussion brain injury. ( Cox, CD; Hayes, RL; Liu, MC; Lyeth, BG; Wang, KK; West, EJ, 2008) |
| "Hyperglycemia has been shown to worsen the outcome of brain ischemia in several animal models but few experimental studies have investigated impairments in cognition induced by ischemic brain lesions in hyperglycemic animals." | 1.34 | Diabetic Goto-Kakizaki rats display pronounced hyperglycemia and longer-lasting cognitive impairments following ischemia induced by cortical compression. ( Cebers, G; Efendic, S; Liljequist, S; Moreira, T; Ostenson, CG; Pickering, C, 2007) |
| " The animals were treated with either one of the drugs at previously defined relevant dosage or control." | 1.33 | Neuronal degeneration and iNOS expression in experimental brain contusion following treatment with colchicine, dexamethasone, tirilazad mesylate and nimodipine. ( Gahm, C; Holmin, S; Mathiesen, T; Rudehill, S, 2005) |
| "Angiogenesis following traumatic brain injuries (TBIs) may be of importance for post-traumatic reparative processes and the development of secondary injuries." | 1.33 | Inhibition of vascular endothelial growth factor receptor 2 activity in experimental brain contusions aggravates injury outcome and leads to early increased neuronal and glial degeneration. ( Holmin, S; Risling, M; Sköld, MK, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (5.81) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 45 (52.33) | 29.6817 |
| 2010's | 36 (41.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Apland, JP | 1 |
| Aroniadou-Anderjaska, V | 1 |
| Figueiredo, TH | 1 |
| De Araujo Furtado, M | 1 |
| Braga, MFM | 1 |
| Gaire, BP | 1 |
| Song, MR | 1 |
| Choi, JW | 1 |
| Liu, W | 1 |
| Li, R | 1 |
| Yin, J | 1 |
| Guo, S | 1 |
| Chen, Y | 1 |
| Fan, H | 1 |
| Li, G | 1 |
| Li, Z | 1 |
| Li, X | 1 |
| Zhang, X | 1 |
| He, X | 1 |
| Duan, C | 1 |
| Hameed, MQ | 1 |
| Goodrich, GS | 1 |
| Dhamne, SC | 1 |
| Amandusson, A | 1 |
| Hsieh, TH | 1 |
| Mou, D | 1 |
| Wang, Y | 2 |
| Rotenberg, A | 1 |
| Neuberger, EJ | 2 |
| Wahab, RA | 2 |
| Jayakumar, A | 1 |
| Pfister, BJ | 2 |
| Santhakumar, V | 2 |
| Huerta-García, E | 1 |
| Pérez-Arizti, JA | 1 |
| Márquez-Ramírez, SG | 1 |
| Delgado-Buenrostro, NL | 1 |
| Chirino, YI | 1 |
| Iglesias, GG | 1 |
| López-Marure, R | 1 |
| Chen, Q | 1 |
| Zhang, J | 1 |
| Guo, J | 1 |
| Tang, J | 1 |
| Tao, Y | 1 |
| Li, L | 1 |
| Feng, H | 1 |
| Chen, Z | 1 |
| Jeong, S | 1 |
| Lei, B | 1 |
| Wang, H | 2 |
| Dawson, HN | 1 |
| James, ML | 2 |
| Xuan, W | 2 |
| Vatansever, F | 2 |
| Huang, L | 2 |
| Hamblin, MR | 2 |
| Lyeth, BG | 5 |
| Dolenec, P | 1 |
| Pilipović, K | 1 |
| Rajič, J | 1 |
| Župan, G | 1 |
| Chen, L | 1 |
| Gao, X | 1 |
| Zhao, S | 1 |
| Hu, W | 1 |
| Chen, J | 1 |
| Febinger, HY | 1 |
| Thomasy, HE | 1 |
| Pavlova, MN | 1 |
| Ringgold, KM | 1 |
| Barf, PR | 1 |
| George, AM | 1 |
| Grillo, JN | 1 |
| Bachstetter, AD | 1 |
| Garcia, JA | 1 |
| Cardona, AE | 1 |
| Opp, MR | 1 |
| Gemma, C | 1 |
| Sukumari-Ramesh, S | 1 |
| Alleyne, CH | 1 |
| Dhandapani, KM | 1 |
| Kwon, SK | 1 |
| Ahn, M | 1 |
| Song, HJ | 1 |
| Kang, SK | 1 |
| Jung, SB | 1 |
| Harsha, N | 1 |
| Jee, S | 1 |
| Moon, JY | 1 |
| Suh, KS | 1 |
| Lee, SD | 1 |
| Jeon, BH | 1 |
| Kim, DW | 1 |
| Kim, CS | 1 |
| Rodrigues, MD | 1 |
| Seminotti, B | 1 |
| Amaral, AU | 1 |
| Leipnitz, G | 1 |
| Goodman, SI | 1 |
| Woontner, M | 1 |
| de Souza, DO | 1 |
| Wajner, M | 1 |
| Hanlon, LA | 1 |
| Huh, JW | 1 |
| Raghupathi, R | 1 |
| Ma, B | 1 |
| Day, JP | 1 |
| Phillips, H | 1 |
| Slootsky, B | 1 |
| Tolosano, E | 1 |
| Doré, S | 1 |
| Ophelders, DR | 1 |
| Gussenhoven, R | 1 |
| Lammens, M | 1 |
| Küsters, B | 1 |
| Kemp, MW | 1 |
| Newnham, JP | 1 |
| Payne, MS | 1 |
| Kallapur, SG | 1 |
| Jobe, AH | 1 |
| Zimmermann, LJ | 1 |
| Kramer, BW | 1 |
| Wolfs, TG | 1 |
| Winston, CN | 1 |
| Noël, A | 1 |
| Neustadtl, A | 1 |
| Parsadanian, M | 1 |
| Barton, DJ | 1 |
| Chellappa, D | 1 |
| Wilkins, TE | 1 |
| Alikhani, AD | 1 |
| Zapple, DN | 1 |
| Villapol, S | 1 |
| Planel, E | 1 |
| Burns, MP | 1 |
| Shiha, AA | 1 |
| de la Rosa, RF | 1 |
| Delgado, M | 1 |
| Pozo, MA | 1 |
| García-García, L | 1 |
| Zhang, B | 2 |
| West, EJ | 2 |
| Van, KC | 1 |
| Gurkoff, GG | 1 |
| Zhou, J | 2 |
| Zhang, XM | 1 |
| Kozikowski, AP | 1 |
| Dennis, AM | 1 |
| Haselkorn, ML | 1 |
| Vagni, VA | 1 |
| Garman, RH | 1 |
| Janesko-Feldman, K | 1 |
| Bayir, H | 1 |
| Clark, RS | 1 |
| Jenkins, LW | 1 |
| Dixon, CE | 1 |
| Kochanek, PM | 1 |
| Cox, CD | 1 |
| Liu, MC | 1 |
| Wang, KK | 1 |
| Hayes, RL | 1 |
| O'Lynnger, T | 1 |
| He, Y | 1 |
| Hu, H | 1 |
| Hua, Y | 1 |
| Muraszko, KM | 1 |
| Xi, G | 1 |
| Di Giorgio, AM | 1 |
| Hou, Y | 1 |
| Zhao, X | 1 |
| Russell, MJ | 1 |
| Hoane, MR | 2 |
| Kaufman, N | 1 |
| Vitek, MP | 1 |
| McKenna, SE | 1 |
| Holmberg, P | 1 |
| Liljequist, S | 3 |
| Wägner, A | 2 |
| Kharatishvili, I | 2 |
| Sierra, A | 1 |
| Immonen, RJ | 1 |
| Gröhn, OH | 1 |
| Pitkänen, A | 2 |
| Lee, JC | 1 |
| Cho, GS | 1 |
| Choi, BO | 1 |
| Kim, HC | 1 |
| Kim, WK | 1 |
| Tsuru-Aoyagi, K | 1 |
| Potts, MB | 1 |
| Trivedi, A | 1 |
| Pfankuch, T | 1 |
| Raber, J | 1 |
| Wendland, M | 1 |
| Claus, CP | 1 |
| Koh, SE | 1 |
| Ferriero, D | 1 |
| Noble-Haeusslein, LJ | 1 |
| Wine, RN | 1 |
| McPherson, CA | 1 |
| Harry, GJ | 1 |
| Zhu, L | 1 |
| Wang, HD | 1 |
| Yu, XG | 1 |
| Jin, W | 1 |
| Qiao, L | 1 |
| Lu, TJ | 1 |
| Hu, ZL | 1 |
| Lee, C | 1 |
| Agoston, DV | 1 |
| Venkatraman, T | 1 |
| Song, P | 1 |
| Lascola, CD | 1 |
| Laskowitz, DT | 1 |
| Reid, WM | 1 |
| Rolfe, A | 1 |
| Register, D | 1 |
| Levasseur, JE | 1 |
| Churn, SB | 1 |
| Sun, D | 1 |
| Bellander, BM | 1 |
| Lidman, O | 1 |
| Ohlsson, M | 1 |
| Meijer, B | 1 |
| Piehl, F | 1 |
| Svensson, M | 1 |
| Zhu, ZF | 1 |
| Wang, QG | 1 |
| Han, BJ | 1 |
| William, CP | 1 |
| Wang, R | 1 |
| Ma, WG | 1 |
| Gao, GD | 1 |
| Mao, QX | 1 |
| Zheng, J | 1 |
| Sun, LZ | 1 |
| Liu, YL | 1 |
| Vandevord, PJ | 1 |
| Bolander, R | 1 |
| Sajja, VS | 1 |
| Hay, K | 1 |
| Bir, CA | 1 |
| Arbeloa, J | 1 |
| Pérez-Samartín, A | 1 |
| Gottlieb, M | 1 |
| Matute, C | 1 |
| Arun, P | 1 |
| Abu-Taleb, R | 1 |
| Valiyaveettil, M | 1 |
| Long, JB | 1 |
| Nambiar, MP | 1 |
| Hua, F | 1 |
| Reiss, JI | 1 |
| Tang, H | 1 |
| Wang, J | 1 |
| Fowler, X | 1 |
| Sayeed, I | 1 |
| Stein, DG | 1 |
| Pan, H | 1 |
| Hu, XZ | 1 |
| Jacobowitz, DM | 1 |
| Chen, C | 1 |
| McDonough, J | 1 |
| Van Shura, K | 1 |
| Lyman, M | 1 |
| Marini, AM | 1 |
| Won, SJ | 1 |
| Kim, JH | 1 |
| Yoo, BH | 1 |
| Sohn, M | 1 |
| Kauppinen, TM | 1 |
| Park, MS | 1 |
| Kwon, HJ | 2 |
| Liu, J | 1 |
| Suh, SW | 1 |
| Shenaq, M | 1 |
| Kassem, H | 1 |
| Peng, C | 1 |
| Schafer, S | 1 |
| Ding, JY | 1 |
| Fredrickson, V | 1 |
| Guthikonda, M | 1 |
| Kreipke, CW | 2 |
| Rafols, JA | 2 |
| Ding, Y | 1 |
| Hawkins, BE | 2 |
| Cowart, JC | 1 |
| Parsley, MA | 2 |
| Capra, BA | 3 |
| Eidson, KA | 3 |
| Hellmich, HL | 4 |
| Dewitt, DS | 4 |
| Prough, DS | 4 |
| Wu, Q | 1 |
| Xuan, Y | 1 |
| Dai, T | 1 |
| Ando, T | 1 |
| Xu, T | 1 |
| Huang, YY | 1 |
| Wu, A | 1 |
| Molteni, R | 1 |
| Ying, Z | 1 |
| Gomez-Pinilla, F | 1 |
| STREICHER, E | 1 |
| WISNIEWSKI, H | 1 |
| KLATZO, I | 1 |
| Anderson, KJ | 2 |
| Fugaccia, I | 2 |
| Scheff, SW | 2 |
| Hallam, TM | 1 |
| Floyd, CL | 2 |
| Folkerts, MM | 1 |
| Lee, LL | 1 |
| Gong, QZ | 1 |
| Muizelaar, JP | 1 |
| Berman, RF | 2 |
| Osteen, CL | 1 |
| Giza, CC | 1 |
| Hovda, DA | 2 |
| Folbergrová, J | 1 |
| Druga, R | 1 |
| Otáhal, J | 1 |
| Haugvicová, R | 1 |
| Mares, P | 1 |
| Kubová, H | 1 |
| Garcia, JM | 2 |
| Shimamura, M | 1 |
| Shah, SA | 1 |
| Avila, MA | 1 |
| Uchida, T | 3 |
| Kennedy, DR | 1 |
| Winston, JH | 1 |
| Miller, KM | 1 |
| Saldanha, CJ | 1 |
| Rohmann, KN | 1 |
| Coomaralingam, L | 1 |
| Wynne, RD | 1 |
| Duckworth, EA | 2 |
| Butler, TL | 1 |
| De Mesquita, D | 1 |
| Collier, SN | 1 |
| Collier, L | 2 |
| Pennypacker, KR | 2 |
| Maeda, M | 1 |
| Ampo, K | 1 |
| Kiryu-Seo, S | 1 |
| Konishi, H | 1 |
| Ohba, N | 1 |
| Kadono, C | 1 |
| Kiyama, H | 1 |
| Capra, B | 1 |
| Eidson, K | 1 |
| Garcia, J | 1 |
| Kennedy, D | 1 |
| Parsley, M | 1 |
| Cowart, J | 1 |
| Gahm, C | 2 |
| Holmin, S | 3 |
| Rudehill, S | 1 |
| Mathiesen, T | 2 |
| Prins, ML | 1 |
| Fujima, LS | 1 |
| Danilov, A | 1 |
| Wiklund, PN | 1 |
| Brundin, L | 1 |
| Moreira, T | 2 |
| Cebers, G | 2 |
| Salehi, M | 1 |
| Ernst, C | 1 |
| Christie, BR | 1 |
| Sköld, MK | 1 |
| Risling, M | 1 |
| Kunz, T | 1 |
| Marklund, N | 1 |
| Hillered, L | 1 |
| Oliw, EH | 1 |
| Butler, T | 1 |
| Collier, S | 1 |
| Rosen, GD | 1 |
| Mesples, B | 1 |
| Hendriks, M | 1 |
| Galaburda, AM | 1 |
| Lapanantasin, S | 1 |
| Chongthammakun, S | 1 |
| Boone, DR | 1 |
| Pickering, C | 1 |
| Ostenson, CG | 1 |
| Efendic, S | 1 |
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| Leutgeb, S | 1 |
| Wu, HQ | 1 |
| Schwarcz, R | 1 |
| Witter, MP | 1 |
| Moser, EI | 1 |
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| Shein, NA | 1 |
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| Alexandrovich, AG | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of Light for Enhancement of Cognition by Transcranial Repeated Application (ELECTRA): a Placebo-Controlled Study of Efficacy, Tolerability and Acceptability in Healthy Adult Volunteers[NCT02817061] | 80 participants (Actual) | Interventional | 2018-03-27 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for erythrosine and Brain Injuries
| Article | Year |
|---|---|
Effects of trauma, hemorrhage and resuscitation in aged rats.
Topics: Age Factors; Aging; Animals; Arterial Pressure; Brain Injuries; Cell Count; Cerebrovascular Circulat | 2013 |
85 other studies available for erythrosine and Brain Injuries
| Article | Year |
|---|---|
Full Protection Against Soman-Induced Seizures and Brain Damage by LY293558 and Caramiphen Combination Treatment in Adult Rats.
Topics: Animals; Anticonvulsants; Body Weight; Brain Injuries; Brain Waves; Cholinesterase Inhibitors; Cyclo | 2018 |
Sphingosine 1-phosphate receptor subtype 3 (S1P
Topics: Animals; Brain Injuries; Calcium-Binding Proteins; Cell Polarity; Cells, Cultured; Disease Models, A | 2018 |
Mesenchymal stem cells alleviate the early brain injury of subarachnoid hemorrhage partly by suppression of Notch1-dependent neuroinflammation: involvement of Botch.
Topics: Animals; Antigens, CD; Blood-Brain Barrier; Brain Injuries; Capillary Permeability; Disease Models, | 2019 |
A rapid lateral fluid percussion injury rodent model of traumatic brain injury and post-traumatic epilepsy.
Topics: Animals; Brain Injuries; Cerebral Ventricles; Disease Models, Animal; Epilepsy, Post-Traumatic; Fluo | 2014 |
Distinct effect of impact rise times on immediate and early neuropathology after brain injury in juvenile rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Injuries; Brain Waves; Chi-Square Distributio | 2014 |
Titanium dioxide nanoparticles induce strong oxidative stress and mitochondrial damage in glial cells.
Topics: Brain Injuries; Catalase; Cell Line, Tumor; Fatty Acids, Unsaturated; Fluoresceins; Glutathione Pero | 2014 |
Chronic hydrocephalus and perihematomal tissue injury developed in a rat model of intracerebral hemorrhage with ventricular extension.
Topics: Animals; Avoidance Learning; Blood Transfusion, Autologous; Brain Edema; Brain Injuries; Capillary P | 2015 |
Intravenous immunoglobulin G improves neurobehavioral and histological outcomes after traumatic brain injury in mice.
Topics: Animals; Antigens, Differentiation; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Cell Co | 2014 |
Transcranial low-level laser therapy enhances learning, memory, and neuroprogenitor cells after traumatic brain injury in mice.
Topics: Animals; Behavior, Animal; Brain Injuries; Caspase 3; DNA-Binding Proteins; Doublecortin Protein; Fl | 2014 |
Fluid percussion injury device for the precise control of injury parameters.
Topics: Aging; Animals; Brain Injuries; Disease Models, Animal; Equipment Design; Fluoresceins; Hippocampus; | 2015 |
Temporal pattern of neurodegeneration, programmed cell death, and neuroplastic responses in the thalamus after lateral fluid percussion brain injury in the rat.
Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Brain Injuries; Craniotomy; Disease Models, Animal; F | 2015 |
The Small-Molecule TrkB Agonist 7, 8-Dihydroxyflavone Decreases Hippocampal Newborn Neuron Death After Traumatic Brain Injury.
Topics: Animals; Animals, Newborn; Azepines; Benzamides; Brain Injuries; Cell Death; Disease Models, Animal; | 2015 |
Time-dependent effects of CX3CR1 in a mouse model of mild traumatic brain injury.
Topics: Analysis of Variance; Animals; Brain; Brain Injuries; CX3C Chemokine Receptor 1; Disease Models, Ani | 2015 |
The Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid (SAHA) Confers Acute Neuroprotection After Intracerebral Hemorrhage in Mice.
Topics: Animals; Brain; Brain Injuries; Cerebral Hemorrhage; Disease Models, Animal; Fluoresceins; Glial Fib | 2016 |
Nafamostat mesilate attenuates transient focal ischemia/reperfusion-induced brain injury via the inhibition of endoplasmic reticulum stress.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Benzamidines; Br | 2015 |
Experimental evidence that overexpression of NR2B glutamate receptor subunit is associated with brain vacuolation in adult glutaryl-CoA dehydrogenase deficient mice: A potential role for glutamatergic-induced excitotoxicity in GA I neuropathology.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic; Brain Injuries; Catalase; | 2015 |
Minocycline Transiently Reduces Microglia/Macrophage Activation but Exacerbates Cognitive Deficits Following Repetitive Traumatic Brain Injury in the Neonatal Rat.
Topics: Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Anti-Bacterial Agents; Antigens, CD; Anti | 2016 |
Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage.
Topics: Acyl-CoA Dehydrogenase; Animals; Arabidopsis Proteins; Brain Injuries; Cells, Cultured; Cerebral Hem | 2016 |
Neuroinflammation and structural injury of the fetal ovine brain following intra-amniotic Candida albicans exposure.
Topics: Animals; Brain Injuries; Calcium-Binding Proteins; Candida albicans; Candidiasis; Caspase 3; Disease | 2016 |
Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma.
Topics: Amyloid; Animals; Behavior, Animal; Brain Concussion; Brain Injuries; Craniocerebral Trauma; Dendrit | 2016 |
Subacute Fluoxetine Reduces Signs of Hippocampal Damage Induced by a Single Convulsant Dose of 4-Aminopyridine in Rats.
Topics: 4-Aminopyridine; Animals; Brain Injuries; Caspase 9; Cell Death; Convulsants; Disease Models, Animal | 2017 |
HDAC inhibitor increases histone H3 acetylation and reduces microglia inflammatory response following traumatic brain injury in rats.
Topics: Acetylation; Analysis of Variance; Animals; Benzamides; Body Temperature; Brain Injuries; CD11b Anti | 2008 |
Hemorrhagic shock after experimental traumatic brain injury in mice: effect on neuronal death.
Topics: Animals; Blast Injuries; Blood Pressure; Brain; Brain Injuries; Cell Count; Cell Death; Disease Mode | 2009 |
Dicyclomine, an M1 muscarinic antagonist, reduces biomarker levels, but not neuronal degeneration, in fluid percussion brain injury.
Topics: Animals; Biomarkers; Blotting, Western; Brain Injuries; Calpain; Caspases; Cell Death; Dicyclomine; | 2008 |
Concomitant intracerebral infusion of tissue plasminogen activator and thrombin leads to brain injury.
Topics: Animals; Basal Ganglia; Blood-Brain Barrier; Brain Injuries; Cell Count; Cell Death; Dose-Response R | 2008 |
Dimethyl sulfoxide provides neuroprotection in a traumatic brain injury model.
Topics: alpha-Tocopherol; Analysis of Variance; Animals; Brain; Brain Injuries; Dimethyl Sulfoxide; Disease | 2008 |
COG1410 improves cognitive performance and reduces cortical neuronal loss in the traumatically injured brain.
Topics: Animals; Apolipoproteins E; Brain Injuries; Cerebral Cortex; Cognition Disorders; Coloring Agents; D | 2009 |
Secondary brain injuries in thalamus and hippocampus after focal ischemia caused by mild, transient extradural compression of the somatosensori cortex in the rat.
Topics: Analysis of Variance; Animals; Behavior, Animal; Blood Gas Analysis; Blood Pressure; Brain Injuries; | 2009 |
Quantitative T2 mapping as a potential marker for the initial assessment of the severity of damage after traumatic brain injury in rat.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Injuries; Brain Mapping; Disease Models, Anim | 2009 |
Aging exacerbates intracerebral hemorrhage-induced brain injury.
Topics: Aging; Animals; Blood Transfusion, Autologous; Blotting, Western; Brain; Brain Injuries; Ciliary Neu | 2009 |
Glutathione peroxidase activity modulates recovery in the injured immature brain.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain Injuries; Disease Models, Animal; Fluoresceins; G | 2009 |
IGF-1 and pAKT signaling promote hippocampal CA1 neuronal survival following injury to dentate granule cells.
Topics: Animals; Animals, Newborn; Brain Injuries; CA1 Region, Hippocampal; Caspase 3; Dentate Gyrus; Diseas | 2009 |
Erythropoietin prevents zinc accumulation and neuronal death after traumatic brain injury in rat hippocampus: in vitro and in vivo studies.
Topics: Analysis of Variance; Animals; Brain Injuries; Cell Count; Cell Death; Cells, Cultured; Chlorides; D | 2009 |
Inhibition of VEGF receptor 2 increased cell death of dentate hilar neurons after traumatic brain injury.
Topics: Animals; Brain Injuries; Cell Death; Dentate Gyrus; Fluoresceins; Fluorescent Dyes; Immunohistochemi | 2009 |
Brain natriuretic peptide improves long-term functional recovery after acute CNS injury in mice.
Topics: Acute Disease; Animals; Brain; Brain Injuries; Cerebral Hemorrhage; Cerebrovascular Circulation; Cog | 2010 |
Strain-related differences after experimental traumatic brain injury in rats.
Topics: Animals; Biomarkers; Brain Injuries; Disease Models, Animal; Electroencephalography; Fluoresceins; F | 2010 |
Association of the severity of cortical damage with the occurrence of spontaneous seizures and hyperexcitability in an animal model of posttraumatic epilepsy.
Topics: Animals; Atrophy; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Electroencephalography; E | 2010 |
Genetic regulation of microglia activation, complement expression, and neurodegeneration in a rat model of traumatic brain injury.
Topics: Animals; Brain Injuries; CD11b Antigen; Complement System Proteins; Disease Models, Animal; Ectodysp | 2010 |
Neuroprotective effect and cognitive outcome of chronic lithium on traumatic brain injury in mice.
Topics: Animals; Antipsychotic Agents; Brain Injuries; Cognition; Fluoresceins; Fluorescent Dyes; Hippocampu | 2010 |
Fluoro jade-C staining in the assessment of brain injury after deep hypothermia circulatory arrest.
Topics: Animals; Brain; Brain Injuries; Cardiopulmonary Bypass; Circulatory Arrest, Deep Hypothermia Induced | 2011 |
Mild neurotrauma indicates a range-specific pressure response to low level shock wave exposure.
Topics: Animals; Apoptosis; Astrocytes; Blast Injuries; Brain Injuries; Caspase 3; Cognition; Fluoresceins; | 2012 |
P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Brain Injuries; Calcium; Cells, Cultured; Cer | 2012 |
Transient changes in neuronal cell membrane permeability after blast exposure.
Topics: Blast Injuries; Brain Injuries; Carbocyanines; Cell Line; Cell Membrane Permeability; Cell Survival; | 2012 |
Progesterone and low-dose vitamin D hormone treatment enhances sparing of memory following traumatic brain injury.
Topics: Animals; Astrocytes; Behavior, Animal; Body Weight; Brain Injuries; Cell Death; Dose-Response Relati | 2012 |
Alpha-linolenic acid is a potent neuroprotective agent against soman-induced neuropathology.
Topics: alpha-Linolenic Acid; Analysis of Variance; Animals; Brain Injuries; Cholinesterase Inhibitors; Dise | 2012 |
Prevention of hypoglycemia-induced neuronal death by minocycline.
Topics: Analysis of Variance; Animals; Blood Glucose; Blood Pressure; Brain Injuries; CD11b Antigen; Cell De | 2012 |
Neuronal damage and functional deficits are ameliorated by inhibition of aquaporin and HIF1α after traumatic brain injury (TBI).
Topics: 2-Methoxyestradiol; Animals; Aquaporin 4; Aquaporins; Brain Damage, Chronic; Brain Edema; Brain Inju | 2012 |
Transcranial low-level laser therapy improves neurological performance in traumatic brain injury in mice: effect of treatment repetition regimen.
Topics: Animals; Behavior, Animal; Brain Injuries; Bromodeoxyuridine; Cell Proliferation; Disease Models, An | 2013 |
A saturated-fat diet aggravates the outcome of traumatic brain injury on hippocampal plasticity and cognitive function by reducing brain-derived neurotrophic factor.
Topics: Animals; Behavior, Animal; Blotting, Western; Brain Injuries; Brain-Derived Neurotrophic Factor; Cog | 2003 |
RESISTANCE OF IMMATURE BRAIN TO EXPERIMENTAL CEREBRAL EDEMA.
Topics: Animals; Animals, Newborn; Autoradiography; Biological Transport; Blood-Brain Barrier; Brain; Brain | 1965 |
Fluoro-jade B stains quiescent and reactive astrocytes in the rodent spinal cord.
Topics: Animals; Astrocytes; Brain Injuries; Female; Fluoresceins; Fluorescent Dyes; Glial Fibrillary Acidic | 2003 |
Comparison of behavioral deficits and acute neuronal degeneration in rat lateral fluid percussion and weight-drop brain injury models.
Topics: Animals; Behavior, Animal; Brain Injuries; Disease Models, Animal; Fluoresceins; Fluorescent Dyes; H | 2004 |
Injury-induced alterations in N-methyl-D-aspartate receptor subunit composition contribute to prolonged 45calcium accumulation following lateral fluid percussion.
Topics: Animals; Autoradiography; Behavior, Animal; Blotting, Western; Brain Injuries; Calcium; Calcium Radi | 2004 |
Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate.
Topics: Amino Acids; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Brain; Brain Chemistry; B | 2005 |
Traumatic brain injury and hemorrhagic hypotension suppress neuroprotective gene expression in injured hippocampal neurons.
Topics: Animals; Apoptosis; Blotting, Northern; Brain Injuries; Fluoresceins; Fluorescent Dyes; Gene Express | 2005 |
Regional distribution of fluoro-jade B staining in the hippocampus following traumatic brain injury.
Topics: Animals; Brain Injuries; Fluoresceins; Fluorescent Dyes; Hippocampus; Male; Organic Chemicals; Rats; | 2005 |
Estrogen provision by reactive glia decreases apoptosis in the zebra finch (Taeniopygia guttata).
Topics: Animals; Apoptosis; Aromatase; Brain Injuries; Cell Count; Drug Interactions; Estrogen Antagonists; | 2005 |
Temporary focal ischemia in the mouse: technical aspects and patterns of Fluoro-Jade evident neurodegeneration.
Topics: Animals; Biomarkers; Brain; Brain Injuries; Cell Death; Cerebral Cortex; Corpus Striatum; Disease Mo | 2005 |
The p53-independent nuclear translocation of cyclin G1 in degenerating neurons by ischemic and traumatic insults.
Topics: Animals; Brain Injuries; Brain Ischemia; Cell Death; Cells, Cultured; Cyclin G; Cyclin G1; Cyclins; | 2005 |
Dose-dependent neuronal injury after traumatic brain injury.
Topics: Analysis of Variance; Animals; Brain Injuries; Caspase 9; Caspases; Cell Count; Disease Models, Anim | 2005 |
Neuronal degeneration and iNOS expression in experimental brain contusion following treatment with colchicine, dexamethasone, tirilazad mesylate and nimodipine.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Brain; Brain Injuries; Calcium Channel Blockers; Cell | 2005 |
Age-dependent reduction of cortical contusion volume by ketones after traumatic brain injury.
Topics: Age Factors; Aging; Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Energy Metabol | 2005 |
Reduced neuronal injury after treatment with NG-nitro-L-arginine methyl ester (L-NAME) or 2-sulfo-phenyl-N-tert-butyl nitrone (S-PBN) following experimental brain contusion.
Topics: Animals; Apoptosis; Benzenesulfonates; Brain; Brain Injuries; Cell Survival; Drug Combinations; Enzy | 2005 |
Impaired long-term habituation is dissociated from increased locomotor activity after sensorimotor cortex compression.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Injuries; Fluoresceins; Functional Laterality | 2006 |
Temporally specific proliferation events are induced in the hippocampus following acute focal injury.
Topics: Animals; Brain Injuries; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Proliferation; Ce | 2006 |
Inhibition of vascular endothelial growth factor receptor 2 activity in experimental brain contusions aggravates injury outcome and leads to early increased neuronal and glial degeneration.
Topics: Angiogenesis Inhibitors; Animals; Brain Injuries; Cell Count; Cell Death; Disease Models, Animal; Fe | 2006 |
Effects of the selective cyclooxygenase-2 inhibitor rofecoxib on cell death following traumatic brain injury in the rat.
Topics: Animals; Brain Injuries; Cell Count; Cell Death; Cyclooxygenase 2 Inhibitors; Disease Models, Animal | 2006 |
NF-kappaB protects neurons from ischemic injury after middle cerebral artery occlusion in mice.
Topics: Animals; beta-Galactosidase; Brain Injuries; Diagnostic Imaging; Fluoresceins; Functional Laterality | 2006 |
Histometric changes and cell death in the thalamus after neonatal neocortical injury in the rat.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Brain Injuries; Brain Mapping; Cell Co | 2006 |
Effects of 17beta-estradiol on intracellular calcium changes and neuronal survival after mechanical strain injury in neuronal-glial cultures.
Topics: Animals; Brain; Brain Injuries; Calcium; Calcium Signaling; Cell Survival; Cells, Cultured; Cocultur | 2006 |
Injured Fluoro-Jade-positive hippocampal neurons contain high levels of zinc after traumatic brain injury.
Topics: Animals; Brain Injuries; Calcium Channel Blockers; Calcium Channels; Cell Count; Cognition Disorders | 2007 |
Diabetic Goto-Kakizaki rats display pronounced hyperglycemia and longer-lasting cognitive impairments following ischemia induced by cortical compression.
Topics: Animals; Blood Glucose; Brain Injuries; Brain Ischemia; Cognition Disorders; Conditioning, Operant; | 2007 |
Extent of nerve cell injury in Marmarou's model compared to other brain trauma models.
Topics: Amyloid beta-Protein Precursor; Animals; Brain Injuries; Cell Death; Diffuse Axonal Injury; Disease | 2007 |
Impaired spatial representation in CA1 after lesion of direct input from entorhinal cortex.
Topics: Action Potentials; Afferent Pathways; Alkynes; Aminocaproates; Animals; Behavior, Animal; Brain Inju | 2008 |
Differential neuroprotective properties of endogenous and exogenous erythropoietin in a mouse model of traumatic brain injury.
Topics: Acclimatization; Animals; Brain Edema; Brain Injuries; Cognition; Erythropoietin; Fluoresceins; Fluo | 2008 |
Nicotinamide treatment provides acute neuroprotection and GFAP regulation following fluid percussion injury.
Topics: Animals; Astrocytes; Behavior, Animal; Brain Chemistry; Brain Injuries; Cell Count; Cerebral Cortex; | 2008 |
Evolution of post-traumatic neurodegeneration after controlled cortical impact traumatic brain injury in mice and rats as assessed by the de Olmos silver and fluorojade staining methods.
Topics: Animals; Brain Injuries; Cerebral Cortex; Copper; Disease Models, Animal; Disease Progression; Fluor | 2008 |
Autophagy is activated and might protect neurons from degeneration after traumatic brain injury.
Topics: Animals; Apoptosis Regulatory Proteins; Astrocytes; Autophagy; Beclin-1; Brain; Brain Injuries; Casp | 2008 |
Distribution of exudated FITC-dextrans in experimental vasogenic brain edema produced by a focal cryogenic injury.
Topics: Animals; Blood Vessels; Brain Edema; Brain Injuries; Cold Temperature; Dextrans; Exudates and Transu | 1984 |
[Results of fluorescein nose endoscopy in the diagnosis of cerebrospinal rhinorrhea].
Topics: Brain Injuries; Brain Neoplasms; Cerebrospinal Fluid Rhinorrhea; Diagnosis, Differential; Endoscopy; | 1984 |
Neuronal injury and loss after traumatic brain injury: time course and regional variability.
Topics: Animals; Brain Injuries; Cerebellum; Cerebral Cortex; Fluoresceins; Fluorescent Dyes; Hippocampus; I | 2001 |
Specific gap junctions enhance the neuronal vulnerability to brain traumatic injury.
Topics: Animals; Animals, Newborn; Brain Injuries; Carbenoxolone; Cell Communication; Cell Count; Cell Death | 2002 |
Interleukin-13 and -4 induce death of activated microglia.
Topics: Animals; Animals, Newborn; Brain Injuries; Cell Death; Cell Size; Cells, Cultured; Encephalitis; Eth | 2002 |
Stereotaxic mapping of the monoamine pathways in the rat brain.
Topics: Amines; Animals; Axons; Brain; Brain Chemistry; Brain Injuries; Brain Mapping; Diencephalon; Dopamin | 1971 |
[Studies on the blood-brain barrier with a fluorescent tracer in human brain edema].
Topics: Animals; Blood-Brain Barrier; Brain Damage, Chronic; Brain Edema; Brain Injuries; Brain Neoplasms; F | 1970 |