erythrosine has been researched along with Brain Hemorrhage, Cerebral, Traumatic in 1 studies
Fluoresceins: A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Gu, Y | 1 |
Hua, Y | 1 |
Keep, RF | 1 |
Morgenstern, LB | 1 |
Xi, G | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Safety and Effectiveness Study of Deferoxamine and Xingnaojing Injection in Intracerebral Hemorrhage[NCT02367248] | Phase 1/Phase 2 | 180 participants (Anticipated) | Interventional | 2015-03-31 | Recruiting | ||
Futility Study of Deferoxamine in Intracerebral Hemorrhage[NCT01662895] | Phase 2 | 42 participants (Actual) | Interventional | 2013-03-18 | Terminated (stopped due to By DSMB on October 18, 2013 due to increased incidence of ARDS. See modified protocol [NCT02175225) | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Mortality at any time from randomization through day-90 (NCT01662895)
Timeframe: 90 days
Intervention | Participants (Count of Participants) |
---|---|
Deferoxamine | 3 |
Normal Saline | 0 |
(NCT01662895)
Timeframe: within 7 days or discharge
Intervention | Participants (Count of Participants) |
---|---|
Deferoxamine | 1 |
Normal Saline | 1 |
(NCT01662895)
Timeframe: within 7 days or discharge
Intervention | Participants (Count of Participants) |
---|---|
Deferoxamine | 0 |
Normal Saline | 1 |
(NCT01662895)
Timeframe: 90 days
Intervention | Participants (Count of Participants) |
---|---|
Deferoxamine | 9 |
Normal Saline | 6 |
(NCT01662895)
Timeframe: 90 days
Intervention | Participants (Count of Participants) |
---|---|
Deferoxamine | 6 |
Normal Saline | 0 |
(NCT01662895)
Timeframe: within 7 days or discharge
Intervention | Participants (Count of Participants) |
---|---|
Deferoxamine | 0 |
Normal Saline | 0 |
"The primary outcome measure of efficacy is the modified Rankin Scale (mRS) score, dichotomized to define good functional outcome as mRS 0-2 at 90 days.~The minimum mRS score is 0 (i.e. no disability). The maximum score is 6 (i.e. dead)." (NCT01662895)
Timeframe: 90 days
Intervention | Participants (Count of Participants) |
---|---|
Deferoxamine | 6 |
Normal Saline | 10 |
The proportion of DFO- and placebo-treated subjects with mRS 0-3 vs. 4-6 at 90 days (NCT01662895)
Timeframe: 90 days
Intervention | Participants (Count of Participants) |
---|---|
Deferoxamine | 12 |
Normal Saline | 14 |
1 other study available for erythrosine and Brain Hemorrhage, Cerebral, Traumatic
Article | Year |
---|---|
Deferoxamine reduces intracerebral hematoma-induced iron accumulation and neuronal death in piglets.
Topics: Animals; Antidotes; Brain; Cell Death; Cerebral Hemorrhage, Traumatic; Deferoxamine; Ferritins; Fluo | 2009 |
Deferoxamine reduces intracerebral hematoma-induced iron accumulation and neuronal death in piglets.
Topics: Animals; Antidotes; Brain; Cell Death; Cerebral Hemorrhage, Traumatic; Deferoxamine; Ferritins; Fluo | 2009 |
Deferoxamine reduces intracerebral hematoma-induced iron accumulation and neuronal death in piglets.
Topics: Animals; Antidotes; Brain; Cell Death; Cerebral Hemorrhage, Traumatic; Deferoxamine; Ferritins; Fluo | 2009 |
Deferoxamine reduces intracerebral hematoma-induced iron accumulation and neuronal death in piglets.
Topics: Animals; Antidotes; Brain; Cell Death; Cerebral Hemorrhage, Traumatic; Deferoxamine; Ferritins; Fluo | 2009 |