erogorgiaene and Tuberculosis

erogorgiaene has been researched along with Tuberculosis* in 1 studies

Other Studies

1 other study(ies) available for erogorgiaene and Tuberculosis

ArticleYear
Asymmetric Total Synthesis of (-)-Erogorgiaene and Its C-11 Epimer and Investigation of Their Antimycobacterial Activity.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2016, Sep-26, Volume: 22, Issue:40

    A short, nine-step, highly enantioselective synthesis of (-)-erogorgiaene and its C-11 epimer is reported. The key stereochemistry controlling steps involve catalytic asymmetric crotylation, anionic oxy-Cope rearrangement and cationic cyclisation. (-)-Erogorgiaene exhibited promising antitubercular activity against multidrug-resistant strains of Mycobacterium tuberculosis.

    Topics: Antitubercular Agents; Chemistry Techniques, Synthetic; Diterpenes; Humans; Mycobacterium tuberculosis; Stereoisomerism; Tuberculosis

2016