erlotinib hydrochloride and Squamous Cell Carcinoma of Head and Neck

Topics: Antibodies, Monoclonal, Humanized; Carcinoma, Squamous Cell; Cetuximab; Clinical Trials as Topic; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Head and Neck Neoplasms; Humans; Neoplasm Metastasis; Quinazolines; Squamous Cell Carcinoma of Head and Neck

Topics: Administration, Metronomic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Female; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Organoplatinum Compounds; Progression-Free Survival; Squamous Cell Carcinoma of Head and Neck

Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Erlotinib Hydrochloride; Female; Humans; Male; Middle Aged; Squamous Cell Carcinoma of Head and Neck

Topics: Adult; Aged; Antineoplastic Agents; Chemoradiotherapy; Cisplatin; Erlotinib Hydrochloride; Female; Head and Neck Neoplasms; Health Status Disparities; Humans; Male; Middle Aged; Quality of Life; Racial Groups; Response Evaluation Criteria in Solid Tumors; Squamous Cell Carcinoma of Head and Neck; Survival Analysis

Topics: Antibodies, Monoclonal; Antibody Specificity; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blotting, Western; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; DNA-Binding Proteins; Endonucleases; Erlotinib Hydrochloride; Female; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Proportional Hazards Models; Prospective Studies; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome

Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cetuximab; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; ErbB Receptors; Erlotinib Hydrochloride; Female; Head and Neck Neoplasms; Humans; Immunoglobulin G; Male; Middle Aged; Panitumumab; Receptor, ErbB-3; Squamous Cell Carcinoma of Head and Neck

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Neoplasms; Carcinoma, Squamous Cell; Child; Child, Preschool; Cytochrome P-450 CYP3A; ErbB Receptors; Erlotinib Hydrochloride; Exanthema; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Protein Kinase Inhibitors; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Young Adult

Topics: Animals; Cachexia; Carcinoma, Lewis Lung; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Erlotinib Hydrochloride; Genes, erbB-1; Head and Neck Neoplasms; Humans; Ligands; Lung Neoplasms; Mice; Parathyroid Hormone-Related Protein; RNA, Messenger; Squamous Cell Carcinoma of Head and Neck

Topics: Animals; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Glucose; Head and Neck Neoplasms; Humans; Lung Neoplasms; Mice; Mouth Neoplasms; Pyruvate Kinase; Quercetin; Squamous Cell Carcinoma of Head and Neck

Topics: Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; Chalcone; Chalcones; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Necrosis; Squamous Cell Carcinoma of Head and Neck; Triazoles

Topics: Carcinoma, Squamous Cell; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Liposomes; Mouth Neoplasms; Squamous Cell Carcinoma of Head and Neck

Topics: Apoptosis; beta Catenin; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Erlotinib Hydrochloride; Head and Neck Neoplasms; Hedgehog Proteins; Humans; Phosphatidylinositol 3-Kinases; Squamous Cell Carcinoma of Head and Neck; Wnt Signaling Pathway

Topics: Antineoplastic Agents; Cell Line, Tumor; Cisplatin; CRISPR-Cas Systems; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Mechanistic Target of Rapamycin Complex 2; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rapamycin-Insensitive Companion of mTOR Protein; Squamous Cell Carcinoma of Head and Neck

Topics: Cell Line, Tumor; Cetuximab; Down-Regulation; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Homeostasis; Humans; Phosphorylation; Squamous Cell Carcinoma of Head and Neck; Tissue Array Analysis

Topics: Antineoplastic Agents; Cell Line, Tumor; Datasets as Topic; Drug Delivery Systems; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Erlotinib Hydrochloride; Genomics; Humans; MAP Kinase Kinase 1; Metabolic Networks and Pathways; Phenotype; Protein Kinase Inhibitors; Proteomics; Squamous Cell Carcinoma of Head and Neck; Whole Genome Sequencing

Topics: Animals; Cell Line, Tumor; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Humans; Mice; Nerve Growth Factor; Paracrine Communication; Receptor, trkA; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

Topics: Antineoplastic Agents; Cell Line, Tumor; Dasatinib; Erlotinib Hydrochloride; Everolimus; Gefitinib; Head and Neck Neoplasms; Human papillomavirus 16; Humans; Papillomavirus Infections; Protein Kinase Inhibitors; Pyrimidines; Receptor, IGF Type 1; Squamous Cell Carcinoma of Head and Neck

Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; ErbB Receptors; Erlotinib Hydrochloride; Head and Neck Neoplasms; High Mobility Group Proteins; Humans; Repressor Proteins; Squamous Cell Carcinoma of Head and Neck; Transcription Factors

Topics: Adult; Aged; Aged, 80 and over; Animals; Carcinogenesis; Cell Line, Tumor; Drug Resistance, Neoplasm; Epiregulin; ErbB Receptors; Erlotinib Hydrochloride; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Head and Neck Neoplasms; Humans; Male; Mice; Middle Aged; Mutation; Proto-Oncogene Proteins c-myc; Squamous Cell Carcinoma of Head and Neck; Up-Regulation; Xenograft Model Antitumor Assays

Topics: Cell Line, Tumor; Dasatinib; Erlotinib Hydrochloride; Everolimus; Fibroblast Growth Factors; Gefitinib; Human papillomavirus 16; Humans; Papillomaviridae; Protein Kinase Inhibitors; Squamous Cell Carcinoma of Head and Neck; TOR Serine-Threonine Kinases

Topics: Animals; Cell Line, Tumor; Diphtheria Toxin; Epidermal Growth Factor; Erlotinib Hydrochloride; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Protein Kinase Inhibitors; Recombinant Fusion Proteins; Squamous Cell Carcinoma of Head and Neck; Xenograft Model Antitumor Assays

Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Cetuximab; ErbB Receptors; Erlotinib Hydrochloride; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Indoles; Mice; Mice, SCID; Mutation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Squamous Cell Carcinoma of Head and Neck; Sulfonamides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zoledronic Acid

Topics: Amino Acids; Carcinoma, Squamous Cell; Cell Culture Techniques; Cell Line, Tumor; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Isotope Labeling; Protein Kinase Inhibitors; Squamous Cell Carcinoma of Head and Neck; Tyrosine

Topics: Afatinib; Antigens, Neoplasm; Antineoplastic Agents; Erlotinib Hydrochloride; Humans; Neoplasm Proteins; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Tumor Cells, Cultured

Topics: Animals; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Drug Administration Schedule; Drug Synergism; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Interferon-alpha; Mice; Receptors, Retinoic Acid; Squamous Cell Carcinoma of Head and Neck; STAT1 Transcription Factor; Up-Regulation; Xenograft Model Antitumor Assays

Topics: Animals; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; I-kappa B Kinase; Mice; NF-kappa B; Oxazines; Protein Kinase Inhibitors; Pyridines; Receptor, ErbB-2; Receptor, ErbB-3; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

Topics: Autophagy; Carcinoma, Squamous Cell; Cytoprotection; ErbB Receptors; Erlotinib Hydrochloride; Head and Neck Neoplasms; HEK293 Cells; Humans; NADPH Oxidase 4; NADPH Oxidases; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Tumor Cells, Cultured

Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Carcinoma, Squamous Cell; Cell Line, Tumor; Cetuximab; Cytokines; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Head and Neck Neoplasms; Humans; Inflammation; Lapatinib; NADPH Oxidase 4; NADPH Oxidases; Oligonucleotide Array Sequence Analysis; Panitumumab; Protein Kinase Inhibitors; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Time Factors

Topics: Animals; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Mice; Molecular Targeted Therapy; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Quinazolines; Sensitivity and Specificity; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Transfection

Topics: Carcinoma, Squamous Cell; ErbB Receptors; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Phenotype; Phosphorylation; Quinazolines; Radiation Tolerance; Radiation, Ionizing; Squamous Cell Carcinoma of Head and Neck; Tumor Cells, Cultured

Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Monensin; Protein Kinase Inhibitors; Quinazolines; Signal Transduction; Squamous Cell Carcinoma of Head and Neck

Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cetuximab; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Female; Head and Neck Neoplasms; Humans; Male; Mice; Mice, Knockout; Mice, Nude; Myeloid Differentiation Factor 88; Quinazolines; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Tumor Cells, Cultured

Topics: Carcinoma, Squamous Cell; Cell Death; Cell Hypoxia; Cell Line, Tumor; Cetuximab; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Inhibitory Concentration 50; Protein Kinase Inhibitors; Squamous Cell Carcinoma of Head and Neck; Tumor Microenvironment

Topics: Adult; Antineoplastic Agents; Biomarkers, Tumor; Biopsy; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; DNA Mutational Analysis; Drug Administration Schedule; ErbB Receptors; Erlotinib Hydrochloride; Genetic Predisposition to Disease; Head and Neck Neoplasms; Humans; Male; Mitogen-Activated Protein Kinase 1; Molecular Targeted Therapy; Mutation; Neoadjuvant Therapy; Neoplasm Staging; Phenotype; Phosphorylation; Predictive Value of Tests; Protein Kinase Inhibitors; Randomized Controlled Trials as Topic; Remission Induction; Squamous Cell Carcinoma of Head and Neck; Time Factors; Tongue Neoplasms; Treatment Outcome

Topics: Carcinoma, Squamous Cell; DNA; DNA Breaks, Double-Stranded; DNA Repair; DNA-Binding Proteins; Enzyme Inhibitors; ErbB Receptors; Erlotinib Hydrochloride; Flavonoids; Head and Neck Neoplasms; Humans; Intracellular Signaling Peptides and Proteins; Phosphorylation; Phthalazines; Piperazines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteomics; RNA Interference; RNA, Small Interfering; Squamous Cell Carcinoma of Head and Neck; Tumor Cells, Cultured; Tumor Suppressor p53-Binding Protein 1

Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Phenylurea Compounds; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Pyridines; RNA Interference; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Time Factors; Transfection; Tumor Burden; Up-Regulation; Xenograft Model Antitumor Assays

Topics: Animals; Antineoplastic Agents; Autophagy; Carcinoma, Squamous Cell; Carrier Proteins; Cell Line, Tumor; Chloroquine; Deoxyglucose; Endoplasmic Reticulum; ErbB Receptors; Erlotinib Hydrochloride; Female; Glucose; Head and Neck Neoplasms; Humans; Membrane Proteins; Mice; Mice, Nude; Protein Kinase Inhibitors; Squamous Cell Carcinoma of Head and Neck; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Transcription Factor CHOP; Xenograft Model Antitumor Assays

Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cetuximab; ErbB Receptors; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Radiation Tolerance; Squamous Cell Carcinoma of Head and Neck; Tumor Suppressor Protein p53

Topics: Animals; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cetuximab; Down-Regulation; ErbB Receptors; Erlotinib Hydrochloride; Female; Gene Knockdown Techniques; Head and Neck Neoplasms; Humans; Male; Mice; Mice, Nude; Mouth Neoplasms; Prognosis; Protein Kinase Inhibitors; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck; Telomeric Repeat Binding Protein 2; Tumor Microenvironment; Xenograft Model Antitumor Assays

Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Cytokines; Disease Models, Animal; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Inflammation Mediators; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Mice; Prognosis; Protein Kinase Inhibitors; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Survival Analysis; Transcriptome; Xenograft Model Antitumor Assays

Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Cytoprotection; Drug Resistance, Neoplasm; Drug Synergism; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Mice; Morpholines; Proto-Oncogene Proteins c-akt; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Erlotinib Hydrochloride; Fluorescent Antibody Technique; Head and Neck Neoplasms; Humans; Insulin-Like Growth Factor Binding Protein 1; Podophyllotoxin; Protein Kinase Inhibitors; Quinazolines; Signal Transduction; Squamous Cell Carcinoma of Head and Neck

Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cetuximab; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Protein Kinase Inhibitors; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Tumor Burden; Xenograft Model Antitumor Assays

Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cetuximab; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Phosphorylation; Quinazolines; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

Topics: Adolescent; Adult; Carcinoma, Squamous Cell; Cell Culture Techniques; Child; Child, Preschool; ErbB Receptors; Erlotinib Hydrochloride; Female; Head and Neck Neoplasms; Humans; Immunoblotting; Immunohistochemistry; Male; Middle Aged; Mouth Mucosa; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Squamous Cell Carcinoma of Head and Neck; STAT3 Transcription Factor; Young Adult

Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Proliferation; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Female; Head and Neck Neoplasms; Humans; Imidazoles; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Mice; Multiprotein Complexes; Quinazolines; Squamous Cell Carcinoma of Head and Neck; TOR Serine-Threonine Kinases; Triazines; Xenograft Model Antitumor Assays