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erlotinib hydrochloride and Experimental Neoplasms

erlotinib hydrochloride has been researched along with Experimental Neoplasms in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (29.41)29.6817
2010's10 (58.82)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Grubbs, CJ; Juliana, MM; Lubet, RA; Miller, MS; Moeinpour, FL; Mohammed, A; Sei, S; Shoemaker, RH; Suen, CS1
Chan Kim, S; Gong, JH; Hong, JK; Hong, SW; Jeong, HR; Jin, DH; Jung, J; Jung, SA; Ki, SY; Kim, DM; Kim, DY; Kim, EH; Kim, J; Kim, MJ; Kim, SM; Kim, TW; Koh, DI; Lee, EY; Lee, S; Lee, SH; Moon, JH; Park, SS; Park, YS; Ryu, YS; Shin, JS; Yu, HN1
Jafari, M; Kennell, C; Lee, JH; Lee, JY; Ruiz-Torres, SJ; Waltz, SE; Zhou, Z1
Tan, S; Wang, G1
Chen, JQ; Giaccone, G; Goldsmith, PK; Heldman, MR; Herrmann, MA; Lee, JH; Park, KS; Wang, Y1
Döme, B; Fehniger, TE; Jansson, B; Laurell, T; Marko-Varga, G; Rezeli, M; Végvári, Á; Welinder, C1
Bernards, R; Cowell, C; de Bruin, EC; Downward, J; García-Castaño, A; Gettinger, S; Gómez-Román, J; Gong, Y; Heideman, DA; Heynen, GJ; Jiang, M; Ladanyi, M; Melnick, MA; Politi, K; Saunders, RE; Smit, EF; Varmus, H; Walther, Z; Warne, PH; Wurtz, A1
Bergbower, E; Dennis, PA; Dogan, I; Ekmekci, A; Gills, JJ; Kawabata, S; Rudin, CM; Wilson, W1
Deng, ZJ; Dreaden, EC; Hammond, PT; Lee, MJ; Morton, SW; Shah, NJ; Shopsowitz, KE; Siouve, E; Yaffe, MB1
Ali, AA; Chen, CY; Chiang, CH; Hsieh, CL; Hsu, FT; Huang, HS; Shiau, CY; Wei, ZH1
He, H; Pei, C; Quyang, L; Shao, Y; Yu, Y; Zhou, Q; Zong, R1
Barr, S; Brown, E; Buck, E; Epstein, D; Eyzaguirre, A; Gibson, NW; Haley, JD; Iwata, KK; Ji, QS; Miglarese, M; Mulvihill, M; O'Connor, M; Pachter, J; Rosenfeld-Franklin, M; Thomson, S; Yao, Y1
Cerniglia, GJ; Choe, R; Durduran, T; Evans, SM; Hahn, SM; Koch, CJ; Lee, WM; Maity, A; Mick, R; Pore, N; Quon, H; Schultz, S; Sehgal, CM; Tsai, JH; Xing, X; Yodh, AG1
Chang, YL; Chen, HJ; Chen, KF; Cheng, AL; Liu, CY; Shiau, CW; Yu, HC1
Alvarez, JV; Bulmer, SE; Chen, TH; Feng, W; Frank, DA; Greulich, H; Hahn, WC; Jänne, PA; Meyerson, M; Sellers, WR; Zappaterra, M1
Birle, DC; Hedley, DW1
Beroukhim, R; Cloughesy, T; DeBiasi, RM; Feng, WL; Gabriel, S; Getz, G; Glatt, KA; Greulich, H; Huang, JH; Kawaguchi, T; Khan, H; King, JC; Leahy, DJ; Lee, JC; Levine, RL; Liau, LM; Linhart, DJ; Mellinghoff, IK; Meyerson, M; Mischel, P; Nelson, SF; Nghiemphu, P; O'Neill, K; Onofrio, R; Paez, JG; Peck, TC; Pieper, RO; Rao, PN; Sawyers, CL; Sellers, WR; Thomas, RK; Vivanco, I; Xu, Q; Yoshimoto, K; Yuza, Y; Ziaugra, L1

Other Studies

17 other study(ies) available for erlotinib hydrochloride and Experimental Neoplasms

ArticleYear
Combination of Erlotinib and Naproxen Employing Pulsatile or Intermittent Dosing Profoundly Inhibits Urinary Bladder Cancers.
    Cancer prevention research (Philadelphia, Pa.), 2020, Volume: 13, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogens; Disease Progression; Drug Administration Schedule; Drug Therapy, Combination; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Naproxen; Neoplasm Recurrence, Local; Neoplasms, Experimental; Pulse Therapy, Drug; Rats; Time Factors; Time-to-Treatment; Urinary Bladder; Urinary Bladder Neoplasms

2020
Inhibition of JAK1/2 can overcome EGFR-TKI resistance in human NSCLC.
    Biochemical and biophysical research communications, 2020, 06-18, Volume: 527, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Janus Kinase 1; Lung Neoplasms; Mice; Mice, Nude; Molecular Structure; Mutation; Neoplasms, Experimental; Protein Kinase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured

2020
Sequential delivery of erlotinib and doxorubicin for enhanced triple negative Breast cancer treatment using polymeric nanoparticle.
    International journal of pharmaceutics, 2017, Sep-15, Volume: 530, Issue:1-2

    Topics: Animals; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Erlotinib Hydrochloride; Female; Humans; Lactates; Mice; Mice, Transgenic; Nanoparticles; Neoplasms, Experimental; Polyethylene Glycols; Triple Negative Breast Neoplasms

2017
Redox-responsive and pH-sensitive nanoparticles enhanced stability and anticancer ability of erlotinib to treat lung cancer in vivo.
    Drug design, development and therapy, 2017, Volume: 11

    Topics: Acrylic Resins; Animals; Antineoplastic Agents; Cell Proliferation; Cystamine; Drug Delivery Systems; Drug Stability; Erlotinib Hydrochloride; Humans; Hydrogen-Ion Concentration; Lipids; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Nanoparticles; Neoplasms, Experimental; Oleic Acid; Oxidation-Reduction; Particle Size; Tumor Cells, Cultured

2017
Capillary isoelectric-focusing immunoassays to study dynamic oncoprotein phosphorylation and drug response to targeted therapies in non-small cell lung cancer.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Humans; Immunoassay; Lung Neoplasms; Lymphatic Metastasis; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mice; Mice, Nude; Molecular Targeted Therapy; Neoplasms, Experimental; Oncogene Proteins; Phosphorylation; Protein Kinase Inhibitors; Quinazolines

2013
Experimental models to study drug distributions in tissue using MALDI mass spectrometry imaging.
    Journal of proteome research, 2013, Dec-06, Volume: 12, Issue:12

    Topics: Adenocarcinoma; Animals; Biological Transport; Cholinergic Antagonists; Erlotinib Hydrochloride; Gefitinib; Humans; Lung Neoplasms; Mice; Microtomy; Neoplasms, Experimental; Protein Kinase Inhibitors; Quinazolines; Scopolamine Derivatives; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tiotropium Bromide; Tissue Culture Techniques; Tumor Microenvironment

2013
Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer.
    Cancer discovery, 2014, Volume: 4, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mice; Neoplasms, Experimental; Neurofibromin 1; Pyridones; Pyrimidinones

2014
SOX2 expression is an early event in a murine model of EGFR mutant lung cancer and promotes proliferation of a subset of EGFR mutant lung adenocarcinoma cell lines.
    Lung cancer (Amsterdam, Netherlands), 2014, Volume: 85, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression; Humans; Lung Neoplasms; Mice, Transgenic; Mutation; Neoplasms, Experimental; Quinazolines; SOXB1 Transcription Factors

2014
A nanoparticle-based combination chemotherapy delivery system for enhanced tumor killing by dynamic rewiring of signaling pathways.
    Science signaling, 2014, May-13, Volume: 7, Issue:325

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Carriers; Erlotinib Hydrochloride; Female; Liposomes; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms, Experimental; Quinazolines

2014
Erlotinib-Conjugated Iron Oxide Nanoparticles as a Smart Cancer-Targeted Theranostic Probe for MRI.
    Scientific reports, 2016, 11-11, Volume: 6

    Topics: Animals; Contrast Media; Drug Delivery Systems; Erlotinib Hydrochloride; Humans; Jurkat Cells; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental

2016
Erlotinib has tumor inhibitory effect in human retinoblastoma cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 85

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Erlotinib Hydrochloride; Humans; Mice; Neoplasms, Experimental; Retinoblastoma

2017
Feedback mechanisms promote cooperativity for small molecule inhibitors of epidermal and insulin-like growth factor receptors.
    Cancer research, 2008, Oct-15, Volume: 68, Issue:20

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Feedback, Physiological; Female; Humans; Imidazoles; Insulin Receptor Substrate Proteins; MAP Kinase Signaling System; Mice; Mice, Nude; Neoplasms, Experimental; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrazines; Quinazolines; Receptor, IGF Type 1; Signal Transduction

2008
Epidermal growth factor receptor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy.
    PloS one, 2009, Aug-06, Volume: 4, Issue:8

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Nude; Neoplasms, Experimental; Oxygen; Quinazolines; Vascular Endothelial Growth Factor A

2009
Inhibition of CIP2A determines erlotinib-induced apoptosis in hepatocellular carcinoma.
    Biochemical pharmacology, 2013, Feb-01, Volume: 85, Issue:3

    Topics: Animals; Apoptosis; Autoantigens; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Nude; Neoplasms, Experimental; Protein Kinase Inhibitors; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Quinazolines; RNA, Small Interfering

2013
Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants.
    PLoS medicine, 2005, Volume: 2, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Exons; Gefitinib; Genetic Therapy; Humans; Mice; Mice, Nude; Mutation; Neoplasms, Experimental; NIH 3T3 Cells; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; STAT3 Transcription Factor; Transfection; Tumor Stem Cell Assay

2005
Signaling interactions of rapamycin combined with erlotinib in cervical carcinoma xenografts.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:10

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Interactions; Epidermal Growth Factor; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Neoplasms, Experimental; Phosphorylation; Quinazolines; Ribosomal Protein S6; Signal Transduction; Sirolimus; Transplantation, Heterologous; Uterine Cervical Neoplasms

2006
Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.
    PLoS medicine, 2006, Volume: 3, Issue:12

    Topics: Animals; Astrocytes; Binding Sites; Cell Line, Tumor; Cell Survival; Cells, Cultured; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Mice; Mice, Nude; Models, Molecular; Mutation, Missense; Neoplasms, Experimental; NIH 3T3 Cells; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Transfection

2006