ergoline and Urination-Disorders

A double-blind prospective trial investigated effects of Nicergoline on micturitional disorders in 60 selected patients with dysuria in the absence of prostate hypertrophy and neurologic disease. Results evaluated from 29 men treated with the product and 25 receiving placebo, taking into account functional improvement and urinary output variations, showed a statistically significant improvement in patients in the Nicergoline group.

Topics: Clinical Trials as Topic; Double-Blind Method; Ergolines; Humans; Male; Nicergoline; Urinary Bladder Neck Obstruction; Urination Disorders

A double blind trial of bromocriptine in the treatment of 14 patients with the symptoms of benign prostatic hypertrophy is reported. 5 patients did not complete the trial mainly because of side-effects due to an overdosage of bromocriptine. In the remaining 9 patients there was symptomatic improvement in 6, with objective evidence of improvement in 3 patients on flow rate measurements. The possible modes of action of bromocriptine in this condition are discussed.

Topics: Aged; Bromocriptine; Clinical Trials as Topic; Ergolines; Humans; Male; Middle Aged; Placebos; Prostatic Hyperplasia; Urinary Tract; Urination; Urination Disorders

Initial experience with the use of bromocriptine in 24 patients with troublesome micturition symptoms associated with an unstable bladder is described. 14 patients responded symptomatically to treatment with bromocriptine and these results were confirmed by a double blind trial in this group. 11 of these patients had previously failed to benefit from treatment either with drugs or vesical distension. It is concluded that bromocriptine has a part to play in the treatment of some cases of primary detrusor instability.

Topics: Adolescent; Adult; Aged; Bromocriptine; Ergolines; Female; Humans; Male; Middle Aged; Urinary Bladder; Urination Disorders