erdafitinib and Disease-Models--Animal

erdafitinib has been researched along with Disease-Models--Animal* in 1 studies

Other Studies

1 other study(ies) available for erdafitinib and Disease-Models--Animal

Article	Year
Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor. Molecular cancer therapeutics, 2017, Volume: 16, Issue:6 Fibroblast growth factor (FGF) signaling plays critical roles in key biological processes ranging from embryogenesis to wound healing and has strong links to several hallmarks of cancer. Genetic alterations in FGF receptor ( Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Humans; Lysosomes; Male; Mice; Molecular Targeted Therapy; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Receptors, Fibroblast Growth Factor; Signal Transduction; Xenograft Model Antitumor Assays	2017

Article

Year

Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor.

Molecular cancer therapeutics, 2017, Volume: 16, Issue:6

Fibroblast growth factor (FGF) signaling plays critical roles in key biological processes ranging from embryogenesis to wound healing and has strong links to several hallmarks of cancer. Genetic alterations in FGF receptor (

Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Humans; Lysosomes; Male; Mice; Molecular Targeted Therapy; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Receptors, Fibroblast Growth Factor; Signal Transduction; Xenograft Model Antitumor Assays

2017