erb-041 and Colorectal-Neoplasms

erb-041 has been researched along with Colorectal-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for erb-041 and Colorectal-Neoplasms

Article	Year
Tumour-suppressive effect of oestrogen receptor β in colorectal cancer patients, colon cancer cells, and a zebrafish model. The Journal of pathology, 2020, Volume: 251, Issue:3 Oestrogen receptor β (ERβ) has been suggested to have anti-proliferative and anti-tumour effects in breast and prostate cancer cells, but other studies have indicated its tumour-promoting effects. Understanding the complex effects of this receptor in different contexts requires further study. We reported that high ERβ expression is independently associated with improved prognosis in female colorectal cancer (CRC) patients. Herein, we investigated the possible anti-tumour effect of ERβ and its selective agonist. CRC patients with high ERβ expression had significantly higher levels of membrane-associated β-catenin, cysteinyl leukotriene receptor 2 (CysLT Topics: Animals; Antineoplastic Agents; Apoptosis; Caco-2 Cells; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Estrogen Receptor beta; Female; Genes, APC; HCT116 Cells; HT29 Cells; Humans; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Metastasis; Oxazoles; Receptors, Leukotriene; Signal Transduction; Xenograft Model Antitumor Assays; Zebrafish	2020

Article

Year

Tumour-suppressive effect of oestrogen receptor β in colorectal cancer patients, colon cancer cells, and a zebrafish model.

The Journal of pathology, 2020, Volume: 251, Issue:3

Oestrogen receptor β (ERβ) has been suggested to have anti-proliferative and anti-tumour effects in breast and prostate cancer cells, but other studies have indicated its tumour-promoting effects. Understanding the complex effects of this receptor in different contexts requires further study. We reported that high ERβ expression is independently associated with improved prognosis in female colorectal cancer (CRC) patients. Herein, we investigated the possible anti-tumour effect of ERβ and its selective agonist. CRC patients with high ERβ expression had significantly higher levels of membrane-associated β-catenin, cysteinyl leukotriene receptor 2 (CysLT

Topics: Animals; Antineoplastic Agents; Apoptosis; Caco-2 Cells; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Estrogen Receptor beta; Female; Genes, APC; HCT116 Cells; HT29 Cells; Humans; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Metastasis; Oxazoles; Receptors, Leukotriene; Signal Transduction; Xenograft Model Antitumor Assays; Zebrafish

2020