erastin has been researched along with Papillomavirus-Infections* in 1 studies
1 other study(ies) available for erastin and Papillomavirus-Infections
Article | Year |
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SLC7A11 as a biomarker and therapeutic target in HPV-positive head and neck Squamous Cell Carcinoma.
Ferroptosis, a regulated form of cell necrosis was previously reported to be induced upon pharmacological targeting of the cystine transporter SLC7A11 in Head and neck Squamous Cell Carcinoma (HNSCC). Whether tumors arising in a context of chronic infection with Human Papillomavirus (HPV) are sensitive to ferroptosis is unknown. Using RNAseq data (both whole-tumor and single-cell sequencing) we report that HPV positive (HPV Topics: Acetylcysteine; Amino Acid Transport System y+; Biological Transport, Active; Biomarkers; Cell Line, Tumor; Cystine; Ferroptosis; Gene Expression Regulation, Neoplastic; Glutathione; Head and Neck Neoplasms; Human papillomavirus 16; Humans; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Papillomavirus Infections; Phospholipid Hydroperoxide Glutathione Peroxidase; Piperazines; Repressor Proteins; RNA-Seq; Single-Cell Analysis; Squamous Cell Carcinoma of Head and Neck | 2020 |