erastin and Carcinoma

erastin has been researched along with Carcinoma* in 1 studies

Other Studies

1 other study(ies) available for erastin and Carcinoma

Article	Year
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC. Cell death & disease, 2023, 08-21, Volume: 14, Issue:8 Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer and is associated with poor prognosis. The histone H3 lysine 36 methyltransferase SET-domain-containing 2 (SETD2) has been reported to be expressed at low levels and frequently mutated in ccRCC. Ferroptosis, a form of death distinct from apoptosis and necrosis, has been reported in recent years in renal cancer. However, the relationship between SETD2 and ferroptosis in renal cancer is not clear. Here, we demonstrated that SETD2 was expressed at low levels in ccRCC and was associated with poor prognosis. Moreover, we found that knockdown of SETD2 increased lipid peroxidation and Fe Topics: Carcinoma; Carcinoma, Renal Cell; Ferroptosis; Histone Methyltransferases; Histones; Humans; Kidney Neoplasms; Lysine	2023

Article

Year

Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC.

Cell death & disease, 2023, 08-21, Volume: 14, Issue:8

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer and is associated with poor prognosis. The histone H3 lysine 36 methyltransferase SET-domain-containing 2 (SETD2) has been reported to be expressed at low levels and frequently mutated in ccRCC. Ferroptosis, a form of death distinct from apoptosis and necrosis, has been reported in recent years in renal cancer. However, the relationship between SETD2 and ferroptosis in renal cancer is not clear. Here, we demonstrated that SETD2 was expressed at low levels in ccRCC and was associated with poor prognosis. Moreover, we found that knockdown of SETD2 increased lipid peroxidation and Fe

Topics: Carcinoma; Carcinoma, Renal Cell; Ferroptosis; Histone Methyltransferases; Histones; Humans; Kidney Neoplasms; Lysine

2023