equilenin has been researched along with Breast Neoplasms in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 9 (75.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bolton, JL; Edirisinghe, P; Geacintov, NE; Qin, Z; Sohn, J; Thatcher, GR; Wang, Z | 1 |
| Blond, SY; Bolton, JL; Chang, M; Elguindi, EC; Li, Y; Liu, X; Pisha, E; Yao, D; Yao, J | 1 |
| Bolton, JL; Chang, M; Li, Y; Mesecar, AD; Nikolic, D; van Breemen, RB; Yager, JD; Yao, J; Yu, L | 1 |
| Bolton, JL; Li, Y; van Breemen, RB; Yang, X | 1 |
| Bolton, JL; Chang, M; Kastrati, I; Overk, CR; Peng, KW; Qin, ZH; Thatcher, GR; Yao, P | 1 |
| Bolton, JL; Chang, M; Kastrati, I; Overk, CR; Peng, KW; Petukhov, P; Qin, ZH; Thatcher, GR; Yao, P | 1 |
| Goldzieher, JW; Moore, PH; Paul, SM; Purdy, RH; Williams, MC | 1 |
| Bolton, JL; Chen, Y; Pisha, E; Shen, L; van Breemen, RB; Xiong, Y; Zhang, F | 1 |
| Blond, SY; Bolton, JL; Chen, Y; Constantinou, AI; Elguindi, EC; Hua, Y; Liu, X; Pisha, E; Shen, L; van Breemen, RB; Zhang, F | 1 |
| Bolton, JL; Hilker, DR; Hussain, MM; Katz, BH; Liu, X; Spink, DC; Zhang, F | 1 |
| Bolton, JL; Hua, Y; Liu, X; Pisha, E; van Breemen, RB; Yang, Y; Yao, J | 1 |
12 other study(ies) available for equilenin and Breast Neoplasms
| Article | Year |
|---|---|
Development of a liquid chromatography electrospray ionization tandem mass spectrometry method for analysis of stable 4-hydroxyequilenin-DNA adducts in human breast cancer cells.
Topics: Animals; Breast Neoplasms; Chromatography, High Pressure Liquid; DNA Adducts; DNA Damage; Equilenin; Female; Humans; Hydrogen-Ion Concentration; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Swine; Tandem Mass Spectrometry; Temperature; Tumor Cells, Cultured | 2009 |
In this issue. Estrogen double whammy.
Topics: Animals; Breast Neoplasms; DNA Damage; Equilenin; Estrogen Replacement Therapy; Horses; Humans; Mice; Oligonucleotides; Reactive Oxygen Species | 2010 |
Inhibition of cellular enzymes by equine catechol estrogens in human breast cancer cells: specificity for glutathione S-transferase P1-1.
Topics: Animals; Breast Neoplasms; Enzyme Inhibitors; Equilenin; Estrogens, Catechol; Glutathione S-Transferase pi; Glutathione Transferase; Horses; Humans; Isoenzymes; Kinetics; Substrate Specificity; Tumor Cells, Cultured | 2002 |
Equine catechol estrogen 4-hydroxyequilenin is a more potent inhibitor of the variant form of catechol-O-methyltransferase.
Topics: Breast Neoplasms; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Equilenin; Estradiol Congeners; Female; Humans; Methylation; Risk Factors; Temperature | 2004 |
Characterization of two new variants of human catechol O-methyltransferase in vitro.
Topics: Alanine; Breast Neoplasms; Catechol O-Methyltransferase; DNA Methylation; Equilenin; Escherichia coli; Estrogen Replacement Therapy; Female; Humans; Mutagenesis, Site-Directed; Plasmids; Polymorphism, Genetic; Serine; Temperature | 2005 |
Activation of estrogen receptor-mediated gene transcription by the equine estrogen metabolite, 4-methoxyequilenin, in human breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Equilenin; Estrogen Receptor alpha; Estrogens; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation; Genes, Reporter; Humans; Ligands; Luciferases; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Response Elements; Transcription, Genetic; Transcriptional Activation; Xenobiotics | 2007 |
Estrogenic activity of the equine estrogen metabolite, 4-methoxyequilenin.
Topics: Alkaline Phosphatase; Animals; Breast Neoplasms; Computer Simulation; Endometrial Neoplasms; Equilenin; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation; Horses; Humans; Luciferases; Response Elements; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured | 2008 |
Relative rates of 2- and 4-hydroxyestrogen synthesis are dependent on both substrate and tissue.
Topics: Animals; Breast Neoplasms; Equilenin; Equilin; Estradiol; Estrogens; Estrogens, Catechol; Ethinyl Estradiol; Female; Humans; Hydroxyestrones; Hydroxylation; Microsomes, Liver; Papio | 1982 |
The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone.
Topics: Animals; Breast Neoplasms; Cytochrome P-450 Enzyme System; Equilenin; Equilin; Estradiol Congeners; Estrone; Female; Humans; Microsomes, Liver; Oxidation-Reduction; Quinones; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tumor Cells, Cultured | 1999 |
A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines.
Topics: Apoptosis; Breast Neoplasms; Cell Survival; Comet Assay; DNA Damage; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Epithelial Cells; Equilenin; Estradiol Congeners; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Tumor Cells, Cultured | 2000 |
Metabolism of equilenin in MCF-7 and MDA-MB-231 human breast cancer cells.
Topics: Aryl Hydrocarbon Hydroxylases; Breast Neoplasms; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Equilenin; Female; Humans; Hydroxylation; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Tumor Cells, Cultured | 2001 |
Oxidative DNA damage induced by equine estrogen metabolites: role of estrogen receptor alpha.
Topics: Binding, Competitive; Breast Neoplasms; Cell Survival; Comet Assay; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Equilenin; Estradiol Congeners; Estrogen Receptor alpha; Female; Humans; Reactive Oxygen Species; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Tumor Cells, Cultured | 2002 |