epoxyazadiradione has been researched along with Neoplasms* in 1 studies
1 other study(ies) available for epoxyazadiradione and Neoplasms
| Article | Year |
|---|---|
Synthesis and evaluation of anti-plasmodial and cytotoxic activities of epoxyazadiradione derivatives.
Epoxyazadiradione (1), a major compound derived from Neem oil, showed modest anti-plasmodial activity against CQ-resistant and CQ-sensitive strains of the most virulent human malaria parasite P. falciparum. A series of analogues were synthesized by modification of the key structural moieties of this high yield natural product. Out of the library of all compounds tested, compounds 3c and 3g have showed modest anti-plasmodial activity against CQ-sensitive (IC Topics: Animals; Antimalarials; Antineoplastic Agents; Azadirachta; Cell Line, Tumor; Cell Proliferation; Humans; Limonins; Malaria; Malaria, Falciparum; Mice; Mice, Inbred BALB C; Neoplasms; Plasmodium berghei; Plasmodium falciparum | 2017 |