eponemycin has been researched along with Leukemia-P388* in 1 studies
1 other study(ies) available for eponemycin and Leukemia-P388
Article | Year |
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Eponemycin, a new antibiotic active against B16 melanoma. I. Production, isolation, structure and biological activity.
Streptomyces hygroscopicus No. P247-71(ATCC 53709)produced a novel antibiotic eponemycin which exhibited specific in vivo antitumor effect against B16 melanoma. Structural studies assigned (4S)-1,2-epoxy-2-hydroxymethyl-4-(N-isooctanoyl-L- serylamino)-6-methylhept-6-ene-3-one to eponemycin which is unrelated to the known antitumor antibiotics. Topics: Amides; Animals; Antibiotics, Antineoplastic; DNA, Neoplasm; Fermentation; Humans; Leukemia L1210; Leukemia P388; Melanoma, Experimental; Mice; Molecular Structure; RNA, Neoplasm; Serine; Streptomyces; Tumor Cells, Cultured | 1990 |