epitiostanol and Neoplasm-Metastasis

epitiostanol has been researched along with Neoplasm-Metastasis* in 1 studies

Other Studies

1 other study(ies) available for epitiostanol and Neoplasm-Metastasis

Article	Year
[A case of advanced breast cancer successfully treated with combined tamoxifen and epitiostanol]. Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:7 A patient with stage IV advanced breast cancer with multiple metastasis (bones of the whole body, lungs) were treated by ovariectomy, administration of an non-steroidal antiestrogen (tamoxifen) and mild chemotherapeutic drugs, with favorable results. After four years, however, the patient had a relapse of the cancer. A steroidal antiestrogen (epitiostanol) was then administered with satisfactory results. When a breast cancer relapse occurs in patients once treated successfully with endocrinotherapy, a different form of endocrinotherapy should be tried. There is a possibility that the mechanism of action of Epitiostanol, which is regarded as a steroidal antiestrogen, is different from that of tamoxifen in which an estrogen receptor (ER) system is included. Topics: Androstanols; Breast Neoplasms; Combined Modality Therapy; Drug Therapy, Combination; Estrogen Antagonists; Female; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Ovariectomy; Tamoxifen	1988

Article

Year

[A case of advanced breast cancer successfully treated with combined tamoxifen and epitiostanol].

Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:7

A patient with stage IV advanced breast cancer with multiple metastasis (bones of the whole body, lungs) were treated by ovariectomy, administration of an non-steroidal antiestrogen (tamoxifen) and mild chemotherapeutic drugs, with favorable results. After four years, however, the patient had a relapse of the cancer. A steroidal antiestrogen (epitiostanol) was then administered with satisfactory results. When a breast cancer relapse occurs in patients once treated successfully with endocrinotherapy, a different form of endocrinotherapy should be tried. There is a possibility that the mechanism of action of Epitiostanol, which is regarded as a steroidal antiestrogen, is different from that of tamoxifen in which an estrogen receptor (ER) system is included.

Topics: Androstanols; Breast Neoplasms; Combined Modality Therapy; Drug Therapy, Combination; Estrogen Antagonists; Female; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Ovariectomy; Tamoxifen

1988