epirizole has been researched along with Duodenal Ulcer in 41 studies
Epirizole: 4-Methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidine. A pyrimidinyl pyrazole with antipyretic, analgesic, and anti-inflammatory activity.
Duodenal Ulcer: A PEPTIC ULCER located in the DUODENUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of active oxygen species and lipid peroxidation in the pathogenesis of duodenal ulcers induced by mepirizole was investigated in rats." | 7.70 | Role of active oxygen species and lipid peroxidation in mepirizole-induced duodenal ulcers in rats. ( Iinuma, S; Kondo, M; Naito, Y; Yoshida, N; Yoshikawa, T, 1998) |
| " Likewise, pantoprazole showed the healing promoting action on chronic duodenal ulcers induced by acetic acid, and this effect was also more potent when compared to omeprazole or lansoprazole." | 7.70 | Effects of pantoprazole, a novel H+/K+-ATPase inhibitor, on duodenal ulcerogenic and healing responses in rats: a comparative study with omeprazole and lansoprazole. ( Kato, S; Konaka, A; Nishijima, M; Takeuchi, K; Yasuhiro, T, 1999) |
| "The role of body temperature in the acid stimulatory mechanism by mepirizole, a duodenal ulcerogen, was investigated in urethane-anesthetized rats." | 7.69 | Acid secretory and duodenal ulcerogenic responses induced by mepirizole in anesthetized rats. Relation to body temperature. ( Ohuchi, T; Okabe, S; Takeuchi, K; Ueshima, K, 1994) |
| "We have investigated the endogenous levels of duodenal calcitonin gene-related peptide- (CGRP) and Substance P- (SP) like immunoreactivity (li) following the induction of duodenal ulcers in rats." | 7.68 | Decrease of duodenal calcitonin gene-related peptide- and substance P-like immunoreactivity in rat duodenal ulcers. ( Evangelista, S; Mantellini, P; Renzi, D; Surrenti, C, 1991) |
| "Duodenal ulcer could be induced in rats by a single subcutaneous injection of the anti-inflammatory agent mepirizole (M) or by the alkyl chemical propionitrile (P)." | 7.68 | Effect of duodenal ulcerogens mepirizole and propionitrile on small intestinal and liver alkaline phosphatase activity in rats. ( Japundzic, I; Levi, E; Rakic-Stojiljkovic, LS, 1990) |
| " Acutely induced gastric ulcers or erosions such as Shay ulcers, water-immersion stress-, indomethacin-, aspirin-, or prednisolone-induced erosions were all markedly inhibited by oral or intraduodenal administration of 10-100 mg/kg of omeprazole." | 7.67 | Effects of a proton pump inhibitor, omeprazole, on gastric secretion and gastric and duodenal ulcers or erosions in rats. ( Okabe, S; Okada, Y; Yamamoto, O, 1984) |
| "The mechanisms by which the potent antiinflammatory agent, mepirizole, causes duodenal ulceration were investigated in the rat." | 7.67 | Decrease in alkaline secretion during duodenal ulceration induced by mepirizole in rats. ( Chen, MH; Jacobson, ED; Joffe, SN; Murphy, RF; Tabata, K, 1984) |
| "The H2-receptor antagonists mifentidine, famotidine, cimetidine and ranitidine were examined for their ability to prevent the duodenal ulcer caused by mepirizole (250 mg/kg p." | 7.67 | Effect of mifentidine on mepirizole-induced duodenal ulcer in the rat. ( Brambilla, A; De Paoli, AM; Ghiorzi, A; Giachetti, A, 1987) |
| "The purpose of these studies was to determine the role played by endogenous prostaglandins in the development of gastric ulcers produced by indomethacin, and of duodenal ulcers produced by mepirizole in rats." | 7.67 | Prostaglandin deficiency by itself is not the cause of mepirizole-induced duodenal ulcers in rats. ( Jacobson, ED; Joffe, SN; Robert, A; Tabata, K, 1987) |
| "Duodenal ulcers were produced in rats following either an oral or parenteral administration of 200 mg/kg of mepirizole, a nonsteroidal antiinflammatory agent." | 7.66 | Mepirizole-induced duodenal ulcers in rats and their pathogenesis. ( Inoo, H; Ishihara, Y; Okabe, S; Tanaka, H, 1982) |
| "Healing processes of duodenal ulcers induced by mepirizole and effects of several drugs on the ulcer healing were studied in rats." | 7.66 | Effects of antiulcer agents on healing of mepirizole-induced duodenal ulcers in rats. ( Ishihara, Y; Okabe, S, 1983) |
| " In this study, we hypothesized that STAT3 signaling is activated and provides a critical protective role that is required for enterocyte survival during the early phases of cysteamine-induced duodenal ulcers." | 3.80 | STAT3 and importins are novel mediators of early molecular and cellular responses in experimental duodenal ulceration. ( Ahluwalia, A; Deng, X; Khomenko, T; Patel, KN; Sandor, Z; Szabo, S; Tarnawski, A, 2014) |
| "The role of active oxygen species and lipid peroxidation in the pathogenesis of duodenal ulcers induced by mepirizole was investigated in rats." | 3.70 | Role of active oxygen species and lipid peroxidation in mepirizole-induced duodenal ulcers in rats. ( Iinuma, S; Kondo, M; Naito, Y; Yoshida, N; Yoshikawa, T, 1998) |
| " On the other hand, a duodenal ulcerogen, mepirizole (200 mg/kg, s." | 3.70 | Effects of S-0509, a novel CCKB/gastrin receptor antagonist, on acid secretion and experimental duodenal ulcers in rats. ( Hirata, T; Ishihara, Y; Ishikawa, M; Kunikata, T; Takeuchi, K; Yamamoto, H, 1999) |
| " Likewise, pantoprazole showed the healing promoting action on chronic duodenal ulcers induced by acetic acid, and this effect was also more potent when compared to omeprazole or lansoprazole." | 3.70 | Effects of pantoprazole, a novel H+/K+-ATPase inhibitor, on duodenal ulcerogenic and healing responses in rats: a comparative study with omeprazole and lansoprazole. ( Kato, S; Konaka, A; Nishijima, M; Takeuchi, K; Yasuhiro, T, 1999) |
| " Animals were administered mepirizole (200 mg/kg, subcutaneously) for induction of duodenal ulcers, and gastric acid and duodenal HCO3- secretions were measured with or without pretreatment with L-NAME (5 mg/kg, intravenously) or nitroprusside (4 mg/kg, intravenously)." | 3.69 | Effects of nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester on duodenal alkaline secretory and ulcerogenic responses induced by mepirizole in rats. ( Ohuchi, T; Okabe, S; Takeuchi, K, 1995) |
| "The role of body temperature in the acid stimulatory mechanism by mepirizole, a duodenal ulcerogen, was investigated in urethane-anesthetized rats." | 3.69 | Acid secretory and duodenal ulcerogenic responses induced by mepirizole in anesthetized rats. Relation to body temperature. ( Ohuchi, T; Okabe, S; Takeuchi, K; Ueshima, K, 1994) |
| ") inhibited mepirizole-induced duodenal ulcers." | 3.69 | YM022 [(R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo-5-phenyl- 1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea], a potent and selective gastrin/cholecystokinin-B receptor antagonist, prevents gastric and duodenal lesions in rats. ( Akuzawa, S; Ito, H; Kamato, T; Kobayashi, A; Miyata, K; Nagakura, Y; Nishida, A; Takinami, Y; Yamano, M; Yuki, H, 1994) |
| "We have investigated the endogenous levels of duodenal calcitonin gene-related peptide- (CGRP) and Substance P- (SP) like immunoreactivity (li) following the induction of duodenal ulcers in rats." | 3.68 | Decrease of duodenal calcitonin gene-related peptide- and substance P-like immunoreactivity in rat duodenal ulcers. ( Evangelista, S; Mantellini, P; Renzi, D; Surrenti, C, 1991) |
| " Z-103 given orally prevented development of gastric lesions induced by water immersion stress, histamine, HCl-aspirin, HCl-ethanol and also duodenal ulcers induced by mepirizole in a dose-dependent manner." | 3.68 | [Studies on anti-ulcer effects of a new compound, zinc L-carnosine (Z-103)]. ( Aita, H; Hori, Y; Morita, H; Okabe, S; Seiki, M; Soeda, M; Tagashira, E; Tanaka, Y; Ueki, S; Yoneta, T, 1990) |
| "Duodenal ulcer could be induced in rats by a single subcutaneous injection of the anti-inflammatory agent mepirizole (M) or by the alkyl chemical propionitrile (P)." | 3.68 | Effect of duodenal ulcerogens mepirizole and propionitrile on small intestinal and liver alkaline phosphatase activity in rats. ( Japundzic, I; Levi, E; Rakic-Stojiljkovic, LS, 1990) |
| " Acutely induced gastric ulcers or erosions such as Shay ulcers, water-immersion stress-, indomethacin-, aspirin-, or prednisolone-induced erosions were all markedly inhibited by oral or intraduodenal administration of 10-100 mg/kg of omeprazole." | 3.67 | Effects of a proton pump inhibitor, omeprazole, on gastric secretion and gastric and duodenal ulcers or erosions in rats. ( Okabe, S; Okada, Y; Yamamoto, O, 1984) |
| "The mechanisms by which the potent antiinflammatory agent, mepirizole, causes duodenal ulceration were investigated in the rat." | 3.67 | Decrease in alkaline secretion during duodenal ulceration induced by mepirizole in rats. ( Chen, MH; Jacobson, ED; Joffe, SN; Murphy, RF; Tabata, K, 1984) |
| " injection of the duodenal ulcerogens cysteamine, propionitrile and mepirizole." | 3.67 | Selective decrease of duodenal phosphoprotein phosphatase activity is a general property of duodenal ulcerogens. ( Japundzić, I; Japundzić, M; Szabó, S, 1989) |
| "The H2-receptor antagonists mifentidine, famotidine, cimetidine and ranitidine were examined for their ability to prevent the duodenal ulcer caused by mepirizole (250 mg/kg p." | 3.67 | Effect of mifentidine on mepirizole-induced duodenal ulcer in the rat. ( Brambilla, A; De Paoli, AM; Ghiorzi, A; Giachetti, A, 1987) |
| "The purposes of this study were to determine whether inhibition of cyclooxygenase is a mechanism by which cysteamine and mepirizole produce duodenal ulcers, identify qualitative or quantitative differences in prostanoid production between gastric mucosa and duodenum, and determine whether differences in cyclooxygenase sensitivity to inhibition by aspirin exist between these two tissues." | 3.67 | Role of prostanoids in experimental duodenal ulcer in rat. ( Kauffman, GL; Kolve, E; Mangus, J; Walfisch, S, 1988) |
| "The effect of the duodenal ulcerogen cysteamine on gastric emptying of a liquid meal was compared to that of two newly identified duodenal ulcerogens, MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and mepirizole." | 3.67 | Biphasic effect of duodenal ulcerogens on gastric emptying in the rat. ( Kline, TJ; Pihan, G; Szabo, S, 1988) |
| "The purpose of these studies was to determine the role played by endogenous prostaglandins in the development of gastric ulcers produced by indomethacin, and of duodenal ulcers produced by mepirizole in rats." | 3.67 | Prostaglandin deficiency by itself is not the cause of mepirizole-induced duodenal ulcers in rats. ( Jacobson, ED; Joffe, SN; Robert, A; Tabata, K, 1987) |
| "Duodenal ulcers were produced in rats following either an oral or parenteral administration of 200 mg/kg of mepirizole, a nonsteroidal antiinflammatory agent." | 3.66 | Mepirizole-induced duodenal ulcers in rats and their pathogenesis. ( Inoo, H; Ishihara, Y; Okabe, S; Tanaka, H, 1982) |
| "Healing processes of duodenal ulcers induced by mepirizole and effects of several drugs on the ulcer healing were studied in rats." | 3.66 | Effects of antiulcer agents on healing of mepirizole-induced duodenal ulcers in rats. ( Ishihara, Y; Okabe, S, 1983) |
| "Indomethacin pretreatment did not significantly augment the duodenal lesions induced by mepirizole or cysteamine, but did augment the gastric lesions induced by these compounds." | 1.27 | Augmentation of cysteamine and mepirizole-induced lesions in the rat duodenum and stomach by histamine or indomethacin. ( Kuwahara, Y; Okabe, S; Tanaka, H, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (48.78) | 18.7374 |
| 1990's | 19 (46.34) | 18.2507 |
| 2000's | 1 (2.44) | 29.6817 |
| 2010's | 1 (2.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khomenko, T | 1 |
| Deng, X | 1 |
| Ahluwalia, A | 1 |
| Tarnawski, A | 1 |
| Patel, KN | 1 |
| Sandor, Z | 1 |
| Szabo, S | 4 |
| Tanaka, J | 1 |
| Iida, H | 1 |
| Abe, M | 1 |
| Yuda, Y | 1 |
| Inoue, S | 1 |
| Okabe, S | 15 |
| Ishihara, Y | 4 |
| Inoo, H | 1 |
| Tanaka, H | 7 |
| Yamamoto, O | 1 |
| Okada, Y | 1 |
| Tabata, K | 2 |
| Jacobson, ED | 2 |
| Chen, MH | 1 |
| Murphy, RF | 1 |
| Joffe, SN | 2 |
| Kauffman, GL | 2 |
| Yamada, Y | 1 |
| Hata, Y | 1 |
| Kunimi, H | 1 |
| Iwata, F | 1 |
| Scremin, OU | 2 |
| Leung, FW | 2 |
| Takeuchi, K | 12 |
| Ohuchi, T | 2 |
| Ueshima, K | 1 |
| Nishida, A | 1 |
| Takinami, Y | 1 |
| Yuki, H | 1 |
| Kobayashi, A | 1 |
| Akuzawa, S | 1 |
| Kamato, T | 1 |
| Ito, H | 1 |
| Yamano, M | 1 |
| Nagakura, Y | 1 |
| Miyata, K | 1 |
| Sekiguchi, H | 1 |
| Hamada, K | 1 |
| Taga, F | 1 |
| Nishino, K | 1 |
| Yamaguchi, T | 1 |
| Aihara, K | 1 |
| Yamada, S | 1 |
| Narita, S | 1 |
| Kogi, K | 1 |
| Terashima, K | 1 |
| Shimamura, H | 1 |
| Kawase, A | 1 |
| Tanaka, Y | 2 |
| Tanimura, T | 1 |
| Kamisaki, T | 1 |
| Ishizuka, Y | 1 |
| Sato, M | 1 |
| Takehara, K | 2 |
| Kato, S | 2 |
| Yagi, K | 1 |
| Kitamura, M | 1 |
| Iinuma, S | 1 |
| Yoshikawa, T | 1 |
| Yoshida, N | 1 |
| Naito, Y | 1 |
| Kondo, M | 1 |
| Hirata, T | 1 |
| Yamamoto, H | 1 |
| Kunikata, T | 1 |
| Ishikawa, M | 1 |
| Konaka, A | 1 |
| Nishijima, M | 1 |
| Yasuhiro, T | 1 |
| Sugamoto, S | 1 |
| Suzuki, K | 1 |
| Kawauchi, S | 1 |
| Furukawa, O | 1 |
| Evangelista, S | 3 |
| Renzi, D | 3 |
| Mantellini, P | 3 |
| Surrenti, C | 3 |
| Meli, A | 2 |
| Seiki, M | 1 |
| Ueki, S | 2 |
| Soeda, M | 1 |
| Hori, Y | 1 |
| Aita, H | 1 |
| Yoneta, T | 1 |
| Morita, H | 1 |
| Tagashira, E | 1 |
| Japundzic, I | 2 |
| Levi, E | 1 |
| Rakic-Stojiljkovic, LS | 1 |
| Schubert, ML | 1 |
| Japundzić, M | 1 |
| Murakami, M | 1 |
| Guth, PH | 1 |
| Mangla, JC | 1 |
| Pihan, G | 2 |
| Brown, HA | 1 |
| Rattan, S | 1 |
| Brambilla, A | 1 |
| Ghiorzi, A | 1 |
| De Paoli, AM | 1 |
| Giachetti, A | 1 |
| Kolve, E | 1 |
| Walfisch, S | 1 |
| Mangus, J | 1 |
| Kline, TJ | 1 |
| Robert, A | 1 |
| Kuwahara, Y | 1 |
| Ohno, T | 1 |
41 other studies available for epirizole and Duodenal Ulcer
| Article | Year |
|---|---|
STAT3 and importins are novel mediators of early molecular and cellular responses in experimental duodenal ulceration.
Topics: Active Transport, Cell Nucleus; alpha Karyopherins; Animals; Apoptosis; beta Karyopherins; Cysteamin | 2014 |
Gastric antisecretory and anti-ulcer effect of ME3407, a new benzimidazole derivative, in rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Cysteamine; Duodenal | 2004 |
Mepirizole-induced duodenal ulcers in rats and their pathogenesis.
Topics: Administration, Oral; Animals; Antacids; Chemical Phenomena; Chemistry; Dose-Response Relationship, | 1982 |
Effects of antiulcer agents on healing of mepirizole-induced duodenal ulcers in rats.
Topics: Aluminum Hydroxide; Animals; Anti-Ulcer Agents; Cimetidine; Drug Combinations; Duodenal Ulcer; Epiri | 1983 |
Effects of a proton pump inhibitor, omeprazole, on gastric secretion and gastric and duodenal ulcers or erosions in rats.
Topics: Animals; Aspirin; Benzimidazoles; Chemical Phenomena; Chemistry; Duodenal Ulcer; Epirizole; Gastric | 1984 |
Decrease in alkaline secretion during duodenal ulceration induced by mepirizole in rats.
Topics: 16,16-Dimethylprostaglandin E2; Alkalies; Animals; Dose-Response Relationship, Drug; Duodenal Ulcer; | 1984 |
Duodenal mucosal protection: the basic truth?
Topics: Animals; Bicarbonates; Duodenal Ulcer; Duodenum; Epirizole; Intestinal Mucosa; Rats | 1984 |
Species and strain differences in mepirizole-induced duodenal and gastric lesions.
Topics: Animals; Dogs; Duodenal Ulcer; Epirizole; Female; Gastric Juice; Guinea Pigs; Male; Mice; Pyrazoles; | 1983 |
Effects of CL-1700 on duodenal ulcer formation in the rat.
Topics: Animals; Anti-Ulcer Agents; Carnosine; Dipeptides; Duodenal Ulcer; Epirizole; Histamine; Male; Rats; | 1982 |
Tobacco cigarette smoke attenuates duodenal ulcer margin hyperemia in the rat. Comparison of IAP clearance and hydrogen gas clearance techniques for measurements of gastrointestinal blood flow.
Topics: Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Duodenal Ulcer; Epirizole; Hydrogen; Hyp | 1995 |
Effects of nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester on duodenal alkaline secretory and ulcerogenic responses induced by mepirizole in rats.
Topics: Animals; Arginine; Bicarbonates; Duodenal Ulcer; Duodenum; Epirizole; Gastric Acid; Intestinal Secre | 1995 |
Acid secretory and duodenal ulcerogenic responses induced by mepirizole in anesthetized rats. Relation to body temperature.
Topics: Animals; Atropine; Body Temperature; Clonidine; Dose-Response Relationship, Drug; Duodenal Ulcer; Ep | 1994 |
YM022 [(R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo-5-phenyl- 1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea], a potent and selective gastrin/cholecystokinin-B receptor antagonist, prevents gastric and duodenal lesions in rats.
Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Duodenal Ulcer; Epirizole; Ethanol; Famotidine; Gastric | 1994 |
Effects of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl] urea with potent gastric mucosal protective activity on acute gastric lesions and duodenal ulcers in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Cyanides; Duodenal Ulcer; Epirizole; Ethanol; Gastric Mucosa; H | 1993 |
Biochemical and pharmacological properties of a newly synthesized proton pump (H+/K(+)-ATPase) inhibitor, TY-11345 in experimental animals.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Benzimidazoles; Duodenal Ulcer; Epirizole; Ethano | 1993 |
Studies on antiulcer agents. IV. Antiulcer effects of 2-benzylthio5,6,7,8-tetrahydro-4(3H)-quinazolinones and related compounds.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Disease Models, Animal; Duodenal Ulcer; Epirizole; | 1995 |
Effect of NG-nitro-L-arginine methyl ester, the nitric oxide synthase inhibitor, on duodenal alkaline secretion and mepirizole-induced duodenal lesions in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbohydrate Metabolism; Duodenal Ulcer; Enzyme In | 1995 |
Effects of pituitary adenylate cyclase activating polypeptide-27 on alkaline secretory and mucosal ulcerogenic responses in rat duodenum.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bicarbonates; Duodenal Ulcer; Duodenum; Epirizole; | 1998 |
Role of active oxygen species and lipid peroxidation in mepirizole-induced duodenal ulcers in rats.
Topics: Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalase; CD18 Antigens; Duodenal Ulc | 1998 |
Effects of S-0509, a novel CCKB/gastrin receptor antagonist, on acid secretion and experimental duodenal ulcers in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzodiazepinones; Benzophenones; Dose-Response Re | 1999 |
Effects of pantoprazole, a novel H+/K+-ATPase inhibitor, on duodenal ulcerogenic and healing responses in rats: a comparative study with omeprazole and lansoprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Anti-Ulcer Agents; Benzimidazoles; Bi | 1999 |
Effects of endothelin-1 on duodenal bicarbonate secretion and mucosal integrity in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antihypertensive Agents; Bicarb | 1999 |
Duodenal SP-like immunoreactivity is decreased in experimentally-induced duodenal ulcers.
Topics: Animals; Cysteamine; Duodenal Ulcer; Epirizole; Female; Immunohistochemistry; Pyrazoles; Pyrimidines | 1990 |
Decrease of duodenal calcitonin gene-related peptide- and substance P-like immunoreactivity in rat duodenal ulcers.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cysteamine; Denervation; Duodenal Ulcer; Duoden | 1991 |
[Studies on anti-ulcer effects of a new compound, zinc L-carnosine (Z-103)].
Topics: Animals; Anti-Ulcer Agents; Aspirin; Carnosine; Dogs; Duodenal Ulcer; Epirizole; Ethanol; Gastric Ac | 1990 |
Effect of duodenal ulcerogens mepirizole and propionitrile on small intestinal and liver alkaline phosphatase activity in rats.
Topics: Alkaline Phosphatase; Animals; Cysteamine; Duodenal Ulcer; Epirizole; Intestine, Small; Liver; Nitri | 1990 |
Pathogenesis of duodenal ulcer.
Topics: Animals; Duodenal Ulcer; Duodenum; Epirizole; Intestinal Mucosa; Rats; Regional Blood Flow; Time Fac | 1990 |
Role of accumulated gastric content in the pathogenesis of cysteamine- and mepirizole-induced duodenal ulcers in the rat.
Topics: Acid-Base Imbalance; Animals; Cysteamine; Duodenal Ulcer; Epirizole; Gastric Emptying; Histamine; Ma | 1990 |
Selective decrease of duodenal phosphoprotein phosphatase activity is a general property of duodenal ulcerogens.
Topics: Animals; Cysteamine; Duodenal Ulcer; Duodenum; Epirizole; Gastric Acid; Intestinal Mucosa; Jejunum; | 1989 |
Effects of the duodenal ulcerogens, mepirizole and cysteamine, on gastric motility and emptying in rats.
Topics: Animals; Coloring Agents; Cysteamine; Duodenal Ulcer; Epirizole; Gastric Emptying; Gastrointestinal | 1989 |
The relationship of intraduodenal pH and delayed gastric emptying in duodenal ulceration induced by mepirizole or cysteamine in rats.
Topics: Animals; Cysteamine; Dose-Response Relationship, Drug; Duodenal Ulcer; Duodenum; Epirizole; Gastric | 1989 |
Pathogenesis of the earliest epithelial cell damage induced by mepirizole and cysteamine in the rat duodenum.
Topics: Animals; Anti-Ulcer Agents; Cysteamine; Duodenal Ulcer; Duodenum; Epirizole; Epithelium; Gastric Aci | 1989 |
Pathogenesis of duodenal ulcer in the rat: dissociation of acid load and blood flow.
Topics: Animals; Blood Pressure; Duodenal Ulcer; Duodenum; Epirizole; Hydrogen-Ion Concentration; Intestinal | 1989 |
Effect of duodenal ulcerogens cysteamine, mepirizole, and MPTP on duodenal myoelectric activity in rats.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cysteamine; Duodenal Ulcer; Duodenum; Epirizo | 1989 |
Duodenal ulcers are associated with a depletion of duodenal calcitonin gene-related peptide-like immunoreactivity in rats.
Topics: Animals; Calcitonin Gene-Related Peptide; Cysteamine; Duodenal Ulcer; Duodenum; Epirizole; Female; N | 1989 |
Effect of mifentidine on mepirizole-induced duodenal ulcer in the rat.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Dose-Response Relationship, Drug; Duodenal Ulcer; Duodenum; | 1987 |
Role of prostanoids in experimental duodenal ulcer in rat.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Cysteamine; Dose-Response Relationship, Drug; Duodenal | 1988 |
Biphasic effect of duodenal ulcerogens on gastric emptying in the rat.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Chronic Disease; Cysteamine; Drug Administrat | 1988 |
Prostaglandin deficiency by itself is not the cause of mepirizole-induced duodenal ulcers in rats.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Dose-Response Relationship, Drug; Drug Interactions; Duoden | 1987 |
Augmentation of cysteamine and mepirizole-induced lesions in the rat duodenum and stomach by histamine or indomethacin.
Topics: Animals; Cysteamine; Disease Models, Animal; Drug Synergism; Duodenal Ulcer; Epirizole; Histamine; I | 1986 |
Pathogenic mechanisms involved in mepirizole-induced duodenal damage in the rat.
Topics: 16,16-Dimethylprostaglandin E2; 6-Ketoprostaglandin F1 alpha; Animals; Bicarbonates; Duodenal Ulcer; | 1986 |