epirizole has been researched along with Disease Models, Animal in 5 studies
Epirizole: 4-Methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidine. A pyrimidinyl pyrazole with antipyretic, analgesic, and anti-inflammatory activity.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we hypothesized that STAT3 signaling is activated and provides a critical protective role that is required for enterocyte survival during the early phases of cysteamine-induced duodenal ulcers." | 3.80 | STAT3 and importins are novel mediators of early molecular and cellular responses in experimental duodenal ulceration. ( Ahluwalia, A; Deng, X; Khomenko, T; Patel, KN; Sandor, Z; Szabo, S; Tarnawski, A, 2014) |
| "Indomethacin pretreatment did not significantly augment the duodenal lesions induced by mepirizole or cysteamine, but did augment the gastric lesions induced by these compounds." | 1.27 | Augmentation of cysteamine and mepirizole-induced lesions in the rat duodenum and stomach by histamine or indomethacin. ( Kuwahara, Y; Okabe, S; Tanaka, H, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Khomenko, T | 1 |
| Deng, X | 1 |
| Ahluwalia, A | 1 |
| Tarnawski, A | 1 |
| Patel, KN | 1 |
| Sandor, Z | 1 |
| Szabo, S | 1 |
| Terashima, K | 1 |
| Shimamura, H | 1 |
| Kawase, A | 1 |
| Tanaka, Y | 1 |
| Tanimura, T | 1 |
| Kamisaki, T | 1 |
| Ishizuka, Y | 1 |
| Sato, M | 1 |
| Ikeda, M | 1 |
| Maruyama, K | 1 |
| Nobuhara, Y | 1 |
| Yamada, T | 1 |
| Okabe, S | 2 |
| Tanaka, H | 1 |
| Kuwahara, Y | 1 |
5 other studies available for epirizole and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
STAT3 and importins are novel mediators of early molecular and cellular responses in experimental duodenal ulceration.
Topics: Active Transport, Cell Nucleus; alpha Karyopherins; Animals; Apoptosis; beta Karyopherins; Cysteamin | 2014 |
Studies on antiulcer agents. IV. Antiulcer effects of 2-benzylthio5,6,7,8-tetrahydro-4(3H)-quinazolinones and related compounds.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Disease Models, Animal; Duodenal Ulcer; Epirizole; | 1995 |
Synthesis and cytoprotective antiulcer activity of 2- or 4-(1H-pyrazol-1-yl)pyrimidine derivatives related to mepirizole and dulcerozine.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Disease Models, Animal; Epirizole; Magnetic Resona | 1996 |
Augmentation of cysteamine and mepirizole-induced lesions in the rat duodenum and stomach by histamine or indomethacin.
Topics: Animals; Cysteamine; Disease Models, Animal; Drug Synergism; Duodenal Ulcer; Epirizole; Histamine; I | 1986 |