epinephrine-sulfate and Pheochromocytoma

epinephrine-sulfate has been researched along with Pheochromocytoma* in 1 studies

Other Studies

1 other study(ies) available for epinephrine-sulfate and Pheochromocytoma

ArticleYear
Catecholamine sulfates as internal standards in HPLC determinations of sulfoconjugated catecholamines in plasma and urine.
    Clinical chemistry, 1991, Volume: 37, Issue:2

    A method is described to measure catecholamine sulfates from human plasma and urine by isocratic reversed-phase high-performance liquid chromatography with electrochemical detection. For this measurement we use catecholamine 3-sulfate isomers as internal standards and determine the sulfoconjugates only after eliminating the catecholamines. Catecholamines that have previously been used as internal standards are shown to cause a significant overestimation (P less than 0.05) of the catecholamine sulfates--by 10% to 25% and 20% to 42% in human plasma and urine, respectively. The detection limits (signal-to-noise ratio greater than 3) in plasma and urine samples were about 80 pmol/L for each analyte. The intra-assay and interassay CVs were less than 4.0% and 10.6% in human plasma and less than 6.6% and 12.8% in human urine, respectively. The calibration curves for all catecholamine sulfates in human plasma and urine were linear (r greater than 0.96; P less than 0.001) over the respective concentration ranges of 0.1-100 nmol/L and 5-1000 nmol/L.

    Topics: Adrenal Gland Neoplasms; Chromatography, High Pressure Liquid; Dopamine; Epinephrine; Humans; Norepinephrine; Pheochromocytoma; Reference Standards

1991