Page last updated: 2024-10-26

epinastine and Disease Models, Animal

epinastine has been researched along with Disease Models, Animal in 10 studies

epinastine: RN given refers parent cpd
epinastine : A benzazepine that is 6,11-dihydro-5H-dibenzo[b,e]azepine in which the azepine ring is fused to the e side of 4,5-dihydro-1H-imidazol-2-amine.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"05% cyclosporine A is as effective as 2% cyclosporine A and epinastine in suppressing mast cell-mediated type I allergic conjunctivitis in an experimental allergic conjunctivitis model."7.79Comparison of the effects of topical cyclosporine a 0.05%, cyclosporine a 2%, epinastine hydrochloride 0.05%, and prednisolone acetate 1% on allergic inflammation in an experimental allergic conjunctivitis model. ( Nigar, V; Semsettin, B; Sinan, E, 2013)
" In this study, we developed epinastine hydrochloride-releasing daily soft contact lenses for treatment of allergic conjunctivitis and examined their in vitro and in vivo performance."3.91In vitro and in vivo performance of epinastine hydrochloride-releasing contact lenses. ( Arai, R; Fukushima, A; Hino, S; Ishida, W; Kishimoto, T; Matsunaga, T; Minami, T; Nakajima, I; Yamagami, S, 2019)
"05% cyclosporine A is as effective as 2% cyclosporine A and epinastine in suppressing mast cell-mediated type I allergic conjunctivitis in an experimental allergic conjunctivitis model."3.79Comparison of the effects of topical cyclosporine a 0.05%, cyclosporine a 2%, epinastine hydrochloride 0.05%, and prednisolone acetate 1% on allergic inflammation in an experimental allergic conjunctivitis model. ( Nigar, V; Semsettin, B; Sinan, E, 2013)
"The aim of this study was to compare the effect of topical olopatadine, epinastine, and lubricant eye drops on dry eye ocular surface disease in the botulinum toxin B (BTX-B)-induced mouse model of keratoconjunctivitis sicca."3.74Effect of topical olopatadine and epinastine in the botulinum toxin B-induced mouse model of dry eye. ( Chuck, RS; Combs, JC; Lekhanont, K; Park, CY; Rangsin, R; Suwan-Apichon, O, 2007)
" Airway eosinophilia in repeatedly antigen-exposed guinea pigs was suppressed by chronic administration of HQL-79 for 2 weeks."1.30Pharmacological studies on the novel antiallergic drug HQL-79: I. Antiallergic and antiasthmatic effects in various experimental models. ( Aritake, K; Hayashi, K; Hayashi, M; Hirotsu, I; Hizue, M; Kimura, Y; Matsushita, N; Mitsui, K; Nakajima, H; Takada, A; Tani, T, 1998)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's4 (40.00)29.6817
2010's4 (40.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Minami, T1
Ishida, W1
Kishimoto, T1
Nakajima, I1
Hino, S1
Arai, R1
Matsunaga, T1
Fukushima, A1
Yamagami, S1
Semsettin, B1
Sinan, E1
Nigar, V1
Suzuki, Y1
Inoue, T1
Yamamoto, A1
Sugimoto, Y2
Tsumuro, T1
Alejandra Hossen, M1
Kishi, Y1
Fujii, Y1
Kamei, C2
Lekhanont, K1
Park, CY1
Combs, JC1
Suwan-Apichon, O1
Rangsin, R1
Chuck, RS1
Werner-Klein, M1
Göggel, R1
Westhof, A1
Erb, KJ1
Matsushita, N1
Hizue, M1
Aritake, K1
Hayashi, K1
Takada, A1
Mitsui, K1
Hayashi, M1
Hirotsu, I1
Kimura, Y1
Tani, T1
Nakajima, H1
Kawamoto, E1
Chen, Z1

Other Studies

10 other studies available for epinastine and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
In vitro and in vivo performance of epinastine hydrochloride-releasing contact lenses.
    PloS one, 2019, Volume: 14, Issue:1

    Topics: Animals; Conjunctivitis, Allergic; Contact Lenses, Hydrophilic; Delayed-Action Preparations; Dibenza

2019
Comparison of the effects of topical cyclosporine a 0.05%, cyclosporine a 2%, epinastine hydrochloride 0.05%, and prednisolone acetate 1% on allergic inflammation in an experimental allergic conjunctivitis model.
    Cornea, 2013, Volume: 32, Issue:11

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Conjunctivitis, Allergic; Cyclosporine;

2013
Prophylactic effects of the histamine H1 receptor antagonist epinastine and the dual thromboxane A2 receptor and chemoattractant receptor-homologous molecule expressed on Th2 cells antagonist ramatroban on allergic rhinitis model in mice.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:4

    Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Benzoquinones; Carbazoles; Dibenzazepines; Disease

2011
Nasal congestion model in Brown Norway rats and the effects of some H1-antagonists.
    International immunopharmacology, 2006, Volume: 6, Issue:5

    Topics: Animals; Chlorpheniramine; Dibenzazepines; Disease Models, Animal; Histamine; Histamine H1 Antagonis

2006
Effect of topical olopatadine and epinastine in the botulinum toxin B-induced mouse model of dry eye.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2007, Volume: 23, Issue:1

    Topics: Administration, Topical; Animals; Botulinum Toxins; Botulinum Toxins, Type A; Dibenzazepines; Dibenz

2007
Development and characterisation of a novel and rapid lung eosinophil influx model in the rat.
    Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:4

    Topics: Alum Compounds; Aminopyridines; Animals; Anti-Inflammatory Agents; Asthma; Benzamides; Bronchoalveol

2008
Pharmacological studies on the novel antiallergic drug HQL-79: I. Antiallergic and antiasthmatic effects in various experimental models.
    Japanese journal of pharmacology, 1998, Volume: 78, Issue:1

    Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Antigens; Bronchoconstriction; Capillary Perme

1998
A new model of allergic rhinitis in rats by topical sensitization and evaluation of H(1)-receptor antagonists.
    Immunopharmacology, 2000, Volume: 48, Issue:1

    Topics: Allergens; Animals; Anti-Allergic Agents; Astemizole; Chlorpheniramine; Dibenzazepines; Disease Mode

2000