Page last updated: 2024-10-26

epinastine and Asthma, Bronchial

epinastine has been researched along with Asthma, Bronchial in 4 studies

epinastine: RN given refers parent cpd
epinastine : A benzazepine that is 6,11-dihydro-5H-dibenzo[b,e]azepine in which the azepine ring is fused to the e side of 4,5-dihydro-1H-imidazol-2-amine.

Research Excerpts

ExcerptRelevanceReference
" When leukocytes from asthmatic patients sensitive to mite were stimulated with the allergen, epinastine inhibited histamine release with a concentration required for 50% inhibition (IC50) of 3 x 10(-5) mol/l and leukotriene C4 generation."3.69Comparison of anti-allergic activities of the histamine H1 receptor antagonists epinastine, ketotifen and oxatomide in human leukocytes. ( Mita, H; Shida, T, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Izumi, N1
Mizuguchi, H1
Umehara, H1
Ogino, S1
Fukui, H1
Werner-Klein, M1
Göggel, R1
Westhof, A1
Erb, KJ1
Mita, H1
Shida, T1
Misawa, M1
Kanai, Y1
Chiba, Y1

Other Studies

4 other studies available for epinastine and Asthma, Bronchial

ArticleYear
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniram

2008
Development and characterisation of a novel and rapid lung eosinophil influx model in the rat.
    Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:4

    Topics: Alum Compounds; Aminopyridines; Animals; Anti-Inflammatory Agents; Asthma; Benzamides; Bronchoalveol

2008
Comparison of anti-allergic activities of the histamine H1 receptor antagonists epinastine, ketotifen and oxatomide in human leukocytes.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:1

    Topics: Asthma; Calcimycin; Dibenzazepines; Histamine H1 Antagonists; Humans; Hypersensitivity; Imidazoles;

1995
Effects of the new antiallergic drug epinastine and ketotifen on repeated antigen challenge-induced airway hyperresponsiveness in rats.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:12

    Topics: Acetylcholine; Animals; Antigens, Helminth; Ascaris; Asthma; Bronchial Hyperreactivity; Dibenzazepin

1991