epimestrol and Intellectual-Disability

The following results were obtained by the authors from follow-up checks of 102 children, aged between 2.5 and eight years, who had been delivered from induced pregnancies. - Developmental abnormalities were recorded from seven cases, in the context of paediatric examinations. Minimal neurological deviations were exhibited by 14 children. Moderate retardation was established in psychological tests from something between 25 and 30 per cent of all cases. Positive responses to electroencephalography, however, without any clinical symptoms were observed in 20 per cent of the probands. Neurological symptoms and moderate retardation were recordable primarily from children who had originated from pathological pregnancies. The above findings are likely to support the recommendation to continue treatment of functional sterility by means of induced ovulation. Yet, treatment of that kind should be restricted to women unlikely to be afflicted with pathological pregnancy, which however, cannot be safely forecast in all cases.

Topics: Adult; Child; Child Development; Child, Preschool; Clomiphene; Electroencephalography; Epimestrol; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intellectual Disability; Male; Nervous System Diseases; Ovulation Induction; Pregnancy