epiglucan has been researched along with Myelodysplastic-Syndromes* in 2 studies
2 other study(ies) available for epiglucan and Myelodysplastic-Syndromes
| Article | Year |
|---|---|
False-positive plasma (1-->3)-beta-D-glucan test following immunoglobulin product replacement in an adult bone marrow recipient.
Topics: Adult; beta-Glucans; Bone Marrow Transplantation; False Positive Reactions; Glucans; Humans; Immunoglobulins; Male; Myelodysplastic Syndromes | 2004 |
Beta-D-glucan as a diagnostic adjunct for invasive fungal infections: validation, cutoff development, and performance in patients with acute myelogenous leukemia and myelodysplastic syndrome.
The Glucatell (1-->3)- beta-D-glucan (BG) detection assay (Associates of Cape Cod) was studied as a diagnostic adjunct for invasive fungal infections (IFIs). On the basis of findings from a preliminary study of 30 candidemic subjects and 30 healthy adults, a serum BG level of >or=60 pg/mL was chosen as the cutoff. Testing was performed with serial serum samples obtained from 283 subjects with acute myeloid leukemia or myelodysplastic syndrome who were receiving antifungal prophylaxis. At least 1 serum sample was positive for BG at a median of 10 days before the clinical diagnosis in 100% of subjects with a proven or probable IFI. IFIs included candidiasis, fusariosis, trichosporonosis, and aspergillosis. Absence of a positive BG finding had a 100% negative predictive value, and the specificity of the test was 90% for a single positive test result and >or=96% for >or=2 sequential positive results. The Glucatell serum BG detection assay is highly sensitive and specific as a diagnostic adjunct for IFI. Topics: Adult; beta-Glucans; Candidiasis; Fungemia; Humans; Leukemia, Myeloid, Acute; Limulus Test; Mycoses; Myelodysplastic Syndromes; Neutropenia; Polysaccharides; Predictive Value of Tests; Proteoglycans; Reagent Kits, Diagnostic; Sensitivity and Specificity | 2004 |