epiglucan and Fatigue

Topics: Adolescent; Adult; Affect; Aged; Anxiety; beta-Glucans; C-Reactive Protein; Chi-Square Distribution; Cholesterol, LDL; Dietary Fiber; Double-Blind Method; Eating; Fasting; Fatigue; Female; Gastrointestinal Tract; Headache; Healthy Volunteers; Humans; Male; Middle Aged; Musculoskeletal Pain; Nutritional Physiological Phenomena; Severity of Illness Index; Young Adult

Topics: Adult; Antioxidants; Autonomic Nervous System; beta-Glucans; Biomarkers; Double-Blind Method; Euglena gracilis; Fatigue; Female; Food Safety; Glucans; Humans; Male; Middle Aged; Oxidative Stress; Young Adult

Topics: Animals; beta-Glucans; Biomarkers; Blood Glucose; Dietary Supplements; Disease Models, Animal; Energy Metabolism; Exercise Tolerance; Fatigue; Gene Expression Regulation; Glycogen; Liver; Male; Mice, Inbred ICR; Muscle Fatigue; Muscle, Skeletal; Oxidative Stress; Swimming; Time Factors

Oat β-glucan was purified from oat bran and its effects on running performance and related biochemical parameters were investigated. Four-week-old male Sparsgue-Dawley rats, fed with/without oat β-glucan (312.5 mg kg(-1) d(-1)) for 7 weeks, were subjected to run on a treadmill system to make them exhausted. All rats were immediately sacrificed after prolonged exercise, and the major metabolic substrates were measured in serum and liver. The results showed feeding dietary oat β-glucan to rats could significantly reduce the body weight and increase the maximum running time compared with normal control (P<0.05). Furthermore, dietary oat β-glucan decreased the levels of blood urea nitrogen, lactate acid, and creatine kinase activity in serum, and increased the levels of non-esterified fatty acids, lactic dehydrogenase activity in serum, and the content of liver glycogen. Therefore, the present study demonstrated that dietary oat β-glucan can enhance the endurance capacity of rats while facilitating their recovery from fatigue.

Topics: Animals; Avena; Behavior, Animal; beta-Glucans; Blood Urea Nitrogen; Body Weight; Chemical Phenomena; Creatine Kinase; Eating; Exercise Test; Fatigue; Fatty Acids, Nonesterified; Glycogen; L-Lactate Dehydrogenase; Lactic Acid; Liver; Male; Muscle, Skeletal; Physical Conditioning, Animal; Physical Endurance; Rats; Rats, Sprague-Dawley; Running

Organic dust exposure and work-related symptoms and effects among household waste recycling workers in Materials Recovery Facilities (MRFs) are a concern. MRFs are a central operation where source-segregated, dry, recyclable materials (paper, plastics, cans, etc.) are sorted, mechanically or manually, to market specifications for processing into secondary materials.. One hundred and fifty-nine MRF workers (91%) from nine MRFs participated. Measurements of airborne total dust, endotoxin, (1-->3)-beta-D-glucan, and a questionnaire survey were carried out. Blood data was restricted to MRFs 3, 6, and 9 (45 workers). Blood sampling investigated differential cell counts, erythrocyte sedimentation rate (ESR), and immunoglobulin (Ig)E.. Workers exposed to higher amounts of endotoxin and (1-->3)-beta-D-glucan had an increased risk for respiratory symptoms as compared to those with lower exposure. Stomach problems was associated to higher (1-->3)-beta-D-glucan exposure. MRF 3 had a higher (1-->3)-beta-d-glucan exposure compared to 6 and 9, and respiratory symptoms, unusual tiredness, and vomiting were reported more often in MRF 3. Monocyte numbers and ESR were significantly decreased in MRF 3 compared to MRF 6 and 9, but all measured values were within normal ranges.. The results suggest that MRF workers exposed to higher levels of endotoxin and (1-->3)-beta-D-glucan at their work sites exhibit various work-related symptoms, and that the longer a worker is in the MRF environment, the more likely he is to become affected by various respiratory and gastrointestinal symptoms.

Topics: Adolescent; Adult; beta-Glucans; Blood Cell Count; Blood Sedimentation; Conservation of Natural Resources; Dust; Endotoxins; Exanthema; Fatigue; Female; Glucans; Humans; Male; Middle Aged; Occupational Exposure; Respiratory Tract Diseases; Surveys and Questionnaires; United Kingdom; Vomiting