epigallocatechin gallate has been researched along with Pancreatic Neoplasms in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (21.43) | 29.6817 |
| 2010's | 20 (71.43) | 24.3611 |
| 2020's | 2 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X; Hu, L; Li, Q; Qiu, S; Wang, F; Xu, X; Zhang, D | 1 |
| Hackman, RM; Mackenzie, GG; Penso, NEC; Wang, Y; Wei, R | 1 |
| Chen, X; Hu, L; Liu, H; Qiu, S; Wang, F; Yang, J; Zhang, D; Zhang, J | 1 |
| Bimonte, S; Caliendo, D; Cascella, M; Cuomo, A; Izzo, F; Leongito, M; Palaia, R | 1 |
| Chao, CY; Chen, WT; Hsieh, CH; Kuo, YY; Lu, CH | 1 |
| Cui, YF; Liu, S; Liu, Y; Wang, XJ | 1 |
| Li, P; Sun, L; Zhang, C | 1 |
| Li, CC; Li, CJ; Li, HM; Liu, S; Liu, Y; Qin, W; Sun, L; Xu, ZL; Zhang, W | 1 |
| Iketaki, K; Ito, K; Kakinuma, E; Masuda, K; Matsuzaki, T; Nakabayashi, S; Sakamoto, R; Sato, Y; Takeuchi, Y; Tanii, T; Yamamoto, H; Yoshikawa, HY | 1 |
| Bi, Y; Liu, X | 1 |
| Anant, S; Dandawate, P; Kaushik, G; Subramaniam, D | 1 |
| Basu, A; Haldar, S | 1 |
| Goggins, M; Hong, SM; Li, A; Omura, N | 1 |
| Arlt, A; Goumas, F; Heise, D; Kalthoff, H; Kürbitz, C; Lemke, J; Redmer, T; Rimbach, G; Trauzold, A | 1 |
| Beppu, Y; Chi, HT; Hara, Y; Ohdomari, I; Sasaki, K; Sato, Y; Tanii, T; Vu, HA; Watanabe, T; Xinh, PT; Yamamoto, H | 1 |
| Brandt, R; Falk, W; Hoffmann, J; Junker, H; Multhoff, G; Radons, J; Schmieder, A; Venz, S | 1 |
| Fu, J; Nall, D; Rodova, M; Shankar, S; Srivastava, RK; Tang, SN | 1 |
| Fu, J; Shankar, S; Srivastava, RK; Tang, SN | 1 |
| Liu, Z; Wang, F; Wang, Y; Zhao, Q; Zhu, Z | 1 |
| Falk, W; Härdtner, C; Multhoff, G; Radons, J | 1 |
| Kostin, SF; McDonald, DE; McFadden, DW | 1 |
| Marsh, L; Shankar, S; Srivastava, RK | 1 |
| Kim, MR; Kim, SO | 1 |
| Kamigaki, T; Koizumi, T; Kuroda, Y; Nakamura, Y; Suzuki, Y; Takada, M; Takeyama, Y; Toyama, H | 1 |
| Basu, A; Das, M; Haldar, S; Qanungo, S | 1 |
| Benghuzzi, H; May, M; Norwood, A; Tan, M; Tucci, M | 1 |
| Shankar, S; Srivastava, RK; Suthakar, G | 1 |
| Ganapathy, S; Hingorani, SR; Shankar, S; Srivastava, RK | 1 |
2 review(s) available for epigallocatechin gallate and Pancreatic Neoplasms
| Article | Year |
|---|---|
An overview of pre-clinical studies on the effects of (-)-epigallocatechin-3-gallate, a catechin found in green tea, in treatment of pancreatic cancer
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Catechin; Disease Progression; Disease-Free Survival; Humans; Pancreatic Neoplasms; Signal Transduction; Tea | 2017 |
Targeting Cancer Stem Cells for Chemoprevention of Pancreatic Cancer.
Topics: Catechin; Doublecortin-Like Kinases; Hedgehog Proteins; Humans; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Neoplastic Stem Cells; Pancreatic Neoplasms; Phytochemicals; Protein Serine-Threonine Kinases; Signal Transduction; Wnt Proteins | 2018 |
26 other study(ies) available for epigallocatechin gallate and Pancreatic Neoplasms
| Article | Year |
|---|---|
Epigallocatechin-3-Gallate Decreases Hypoxia-Inducible Factor-1 in Pancreatic Cancer Cells.
Topics: Animals; Hypoxia; Hypoxia-Inducible Factor 1; Mammals; Mice; Pancreatic Neoplasms | 2023 |
Epigallocatechin-3-Gallate (EGCG) Suppresses Pancreatic Cancer Cell Growth, Invasion, and Migration partly through the Inhibition of Akt Pathway and Epithelial-Mesenchymal Transition: Enhanced Efficacy when Combined with Gemcitabine.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Deoxycytidine; Enzyme Stability; Epithelial-Mesenchymal Transition; Gemcitabine; Humans; Mice, Inbred C57BL; Neoplasm Invasiveness; Pancreatic Neoplasms; Proteolysis; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Burden | 2019 |
Intra-Pancreatic Insulin Nourishes Cancer Cells: Do Insulin-Receptor Antagonists such as PGG and EGCG Play a Role?
Topics: Animals; Catechin; Cell Line, Tumor; Gene Expression; Humans; Hydrolyzable Tannins; Insulin; Insulin-Like Growth Factor I; Male; Mice, Nude; Pancreatic Neoplasms; Receptor, Insulin; Streptozocin | 2020 |
Thermal cycling-hyperthermia in combination with polyphenols, epigallocatechin gallate and chlorogenic acid, exerts synergistic anticancer effect against human pancreatic cancer PANC-1 cells.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Chlorogenic Acid; Combined Modality Therapy; Drug Synergism; Humans; Hyperthermia, Induced; Mitochondria; Pancreatic Neoplasms; Polyphenols | 2019 |
PI3K/AKT/mTOR signaling is involved in (-)-epigallocatechin-3-gallate-induced apoptosis of human pancreatic carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camellia sinensis; Catechin; Cell Line, Tumor; Cell Proliferation; Humans; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinase; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation | 2013 |
Copolymeric micelles for delivery of EGCG and cyclopamine to pancreatic cancer cells.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Down-Regulation; Drug Delivery Systems; ErbB Receptors; Hedgehog Proteins; Humans; Micelles; Pancreatic Neoplasms; Phosphorylation; Polyesters; Polyethylene Glycols; Polymers; Signal Transduction; Veratrum Alkaloids | 2014 |
(‑)‑Epigallocatechin‑3‑gallate induces apoptosis in human pancreatic cancer cells via PTEN.
Topics: Apoptosis; Catechin; Cell Proliferation; Gene Knockdown Techniques; Humans; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; RNA Interference; RNA, Small Interfering; Signal Transduction | 2016 |
Quantitative comparison of cancer and normal cell adhesion using organosilane monolayer templates: an experimental study on the anti-adhesion effect of green-tea catechins.
Topics: Catechin; Cell Adhesion; Cell Line, Tumor; Humans; Pancreas; Pancreatic Neoplasms; Tea | 2016 |
Y-27632 Increases Sensitivity of PANC-1 Cells to EGCG in Regulating Cell Proliferation and Migration.
Topics: Amides; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug Synergism; Humans; Pancreatic Neoplasms; PPAR alpha; Pyridines; RNA, Messenger | 2016 |
Combinatorial effect of epigallocatechin-3-gallate and TRAIL on pancreatic cancer cell death.
Topics: Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 8; Caspase 9; Catechin; Cell Line, Tumor; Enzyme Activation; Fas-Associated Death Domain Protein; Humans; Immunoblotting; Pancreatic Neoplasms; Protease Inhibitors; Ribonucleases; TNF-Related Apoptosis-Inducing Ligand; Tumor Stem Cell Assay | 2009 |
Pancreatic cancer DNMT1 expression and sensitivity to DNMT1 inhibitors.
Topics: Azacitidine; Catechin; Cell Line, Tumor; Cell Proliferation; Chromosomes, Human, Pair 19; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Gene Dosage; Humans; Mutation; Pancreatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins | 2010 |
Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Blotting, Western; Carcinoma, Pancreatic Ductal; Catechin; Cell Cycle; Cell Proliferation; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorescent Antibody Technique; Humans; Pancreatic Neoplasms; Tea; Tumor Cells, Cultured | 2011 |
Green tea epigallocatechin gallate exhibits anticancer effect in human pancreatic carcinoma cells via the inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Focal Adhesion Kinase 1; Humans; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Receptor, IGF Type 1; Tea | 2010 |
EGCG downregulates IL-1RI expression and suppresses IL-1-induced tumorigenic factors in human pancreatic adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Interleukin-1; Matrix Metalloproteinase 2; Pancreatic Neoplasms; Receptors, Interleukin-1 Type I; Vascular Endothelial Growth Factor A | 2011 |
Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics.
Topics: Apoptosis; Caspase 3; Catechin; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Epithelial-Mesenchymal Transition; Hedgehog Proteins; Homeodomain Proteins; Humans; Nanog Homeobox Protein; Neoplastic Stem Cells; Octamer Transcription Factor-3; Pancreatic Neoplasms; Plant Extracts; Pluripotent Stem Cells; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Quercetin; Signal Transduction; TCF Transcription Factors; Tea; Transcription, Genetic; X-Linked Inhibitor of Apoptosis Protein | 2012 |
EGCG enhances the therapeutic potential of gemcitabine and CP690550 by inhibiting STAT3 signaling pathway in human pancreatic cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Pancreatic Neoplasms; Piperidines; Pyrimidines; Pyrroles; Signal Transduction; STAT3 Transcription Factor | 2012 |
Inhibitory effects of epigallocatechin-3-gallate on cell proliferation and the expression of HIF-1α and P-gp in the human pancreatic carcinoma cell line PANC-1.
Topics: Antineoplastic Agents; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma; Catechin; Cell Line, Tumor; Cell Proliferation; Gene Expression; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Pancreatic Neoplasms; RNA, Messenger; Transcription, Genetic | 2012 |
(-)-Epigallocatechin-3-gallate, a green tea-derived catechin, synergizes with celecoxib to inhibit IL-1-induced tumorigenic mediators by human pancreatic adenocarcinoma cells Colo357.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Camellia sinensis; Caspases; Catechin; Celecoxib; Cell Line, Tumor; Cyclooxygenase 2; Drug Synergism; Humans; Interleukin-1; Pancreatic Neoplasms; Pyrazoles; Sulfonamides | 2012 |
Inhibitory effects of (-)-epigallocatechin-3-gallate and pterostilbene on pancreatic cancer growth in vitro.
Topics: Anticarcinogenic Agents; Carcinoma; Caspases; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytochromes c; DNA Fragmentation; Drug Evaluation, Preclinical; Humans; Pancreatic Neoplasms; Stilbenes | 2012 |
EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Catechin; Cell Line, Tumor; Cell Proliferation; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Neuropilins; Pancreas; Pancreatic Neoplasms; Proliferating Cell Nuclear Antigen; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
(-)-Epigallocatechin 3-gallate inhibits invasion by inducing the expression of Raf kinase inhibitor protein in AsPC‑1 human pancreatic adenocarcinoma cells through the modulation of histone deacetylase activity.
Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Cadherins; Catechin; Cell Movement; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Histone Deacetylases; Humans; Matrix Metalloproteinase 2; Neoplasm Invasiveness; NF-kappa B; Pancreatic Neoplasms; Phosphatidylethanolamine Binding Protein; Phosphorylation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 2013 |
Suppression of human pancreatic carcinoma cell growth and invasion by epigallocatechin-3-gallate.
Topics: Antineoplastic Agents, Phytogenic; Biocompatible Materials; Carcinoma; Catechin; Cell Division; Collagen; Cyclin D1; Drug Combinations; Humans; Laminin; Neoplasm Invasiveness; Pancreatic Neoplasms; Proteoglycans; Tea; Tumor Cells, Cultured | 2002 |
Epigallocatechin-3-gallate induces mitochondrial membrane depolarization and caspase-dependent apoptosis in pancreatic cancer cells.
Topics: Antioxidants; Apoptosis; Caspases; Catechin; Cell Proliferation; Cytochromes c; Cytosol; G2 Phase; Humans; JNK Mitogen-Activated Protein Kinases; Membrane Potentials; Mitochondria; Pancreatic Neoplasms; Signal Transduction; Tea | 2005 |
Effects of (-)epigallocatechin gallate and thymoquinone on proliferation of a PANC-1 cell line in culture.
Topics: Adenocarcinoma; Antineoplastic Agents; Antioxidants; Benzoquinones; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Pancreatic Neoplasms; Treatment Outcome | 2006 |
Epigallocatechin-3-gallate inhibits cell cycle and induces apoptosis in pancreatic cancer.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspase 3; Catechin; Cell Cycle; Cell Line, Tumor; Enzyme Activation; Humans; MAP Kinase Signaling System; Mice; Mice, Knockout; Mitochondria; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2007 |
EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer.
Topics: Animals; Catechin; Cell Proliferation; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Pancreatic Neoplasms | 2008 |