Page last updated: 2024-08-24

epigallocatechin gallate and Melanoma

epigallocatechin gallate has been researched along with Melanoma in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (42.31)29.6817
2010's12 (46.15)24.3611
2020's3 (11.54)2.80

Authors

AuthorsStudies
Acoca, S; Beauparlant, P; Bélec, L; Billot, X; Cluse, L; Goulet, D; Johnstone, RW; Marcellus, RC; Murthy Madiraju, SR; Nguyen, M; Purisima, E; Roulston, A; Serfass, L; Shore, GC; Viallet, J; Watson, M; Wiegmans, A1
DU, BX; Lin, J; Lin, P1
Darwish, NH; Mousa, SA; Salaheldin, TA; Sudha, T1
Lee, J; Li, X; Wang, Y; Xu, A; Xu, P; Zhao, Y1
Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW1
Ashby, CR; Chauhan, H; Heenatigala Palliyage, G; Singh, S; Tiwari, AK1
Tong, LX; Young, LC1
Adhami, VM; Bharali, DJ; Chamcheu, JC; Khan, MI; Khan, N; Mousa, SA; Mukhtar, H; Nihal, M; Shabana, S; Siddiqui, IA1
Chang, CW; Chen, Y; Hsieh, YH; Hu, DN; Yang, SF; Yang, WE1
Huang, Y; Kim, Y; Kumazoe, M; Murata, M; Tachibana, H; Tsukamoto, S; Umeda, D; Yamada, K; Yamada, S; Yamashita, S1
Huang, Y; Kumazoe, M; Makio, A; Tachibana, H; Tsukamoto, S; Yamada, S; Yamashita, S1
Chen, X; Huang, Z; Lei, Z; Luo, Z; Peng, C; Su, J; Zeng, W; Zhang, J; Zhang, X; Zhou, Y1
Li, J; Lin, Y; Liu, H; Wu, Y1
Ahmad, N; Ahsan, H; Mukhtar, H; Nihal, M; Siddiqui, IA; Wood, GS1
Wu, S1
Hida, K; Hida, Y; Matsuda, K; Muraki, C; Ohga, N; Ohiro, Y; Shindoh, M; Totsuka, Y; Tsuchiya, K1
Jiang, P; Li, J; Li, Y; Lu, J; Shen, Q; Tian, F; Zhang, L1
Nihal, M; Roelke, CT; Wood, GS1
Dunn, JH; Ellis, LZ; Fujita, M; Liu, W; Luo, Y; Okamoto, M; Qu, D1
Katiyar, SK; Singh, T1
Amor, R; Blatchford, DR; Chang, CW; Dufès, C; Lemarié, F; McConnell, G; Norris, G; Tetley, L1
Jeon, SE; Kim, DS; Park, KC1
Ahmad, N; Mukhtar, H; Nihal, M; Wood, GS1
Chiang, HS; Huang, TF; Hung, CF; Wu, WB1
Fang, JY; Huang, YL; Lee, WR; Shen, SC1
Cheng, TO1

Reviews

2 review(s) available for epigallocatechin gallate and Melanoma

ArticleYear
Pharmaceutical Topical Delivery of Poorly Soluble Polyphenols: Potential Role in Prevention and Treatment of Melanoma.
    AAPS PharmSciTech, 2019, Jul-11, Volume: 20, Issue:6

    Topics: Animals; Antioxidants; Biological Availability; Catechin; Curcumin; Drug Delivery Systems; Humans; Melanoma; Nanoparticles; Polyphenols; Quercetin; Resveratrol; Skin Neoplasms; Solubility

2019
Nutrition: the future of melanoma prevention?
    Journal of the American Academy of Dermatology, 2014, Volume: 71, Issue:1

    Topics: Antioxidants; Carotenoids; Catechin; Diet; Grape Seed Extract; Humans; Lycopene; Melanoma; Nutrition Policy; Proanthocyanidins; Resveratrol; Selenium; Skin Neoplasms; Stilbenes; Vitamin D; Vitamin E

2014

Other Studies

24 other study(ies) available for epigallocatechin gallate and Melanoma

ArticleYear
Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-04, Volume: 104, Issue:49

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Boronic Acids; Bortezomib; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Drug Resistance, Neoplasm; Humans; Indoles; Melanoma; Mice; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Proteasome Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Pyrroles

2007
EGCG and ECG induce apoptosis and decrease autophagy via the AMPK/mTOR and PI3K/AKT/mTOR pathway in human melanoma cells.
    Chinese journal of natural medicines, 2022, Volume: 20, Issue:4

    Topics: AMP-Activated Protein Kinases; Apoptosis; Autophagy; Catechin; Electrocardiography; Humans; Melanoma; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2022
Antitumor/anti-angiogenesis efficacy of epigallocatechin gallate nanoformulated with antioxidant in melanoma.
    Nanomedicine (London, England), 2022, Volume: 17, Issue:15

    Topics: Antioxidants; Catechin; Humans; Lycopene; Melanoma; Olive Oil; Tea; Zinc Oxide

2022
Potential effect of EGCG on the anti-tumor efficacy of metformin in melanoma cells.
    Journal of Zhejiang University. Science. B, 2021, Jul-15, Volume: 22, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cell Survival; Cytokines; Cytoplasm; Inflammation; Melanoma; Melanoma, Experimental; Metformin; Mice; NF-kappa B p50 Subunit; Oxidative Stress; Phosphorylation; Skin Neoplasms; Spectrum Analysis, Raman; STAT3 Transcription Factor

2021
Modulation of MMP-2 and -9 secretion by cytokines, inducers and inhibitors in human melanoma A-2058 cells.
    Oncology reports, 2017, Volume: 37, Issue:6

    Topics: Catechin; Cell Line, Tumor; Cytokines; Doxycycline; Humans; Interleukin-1beta; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Melanoma; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2017
Excellent anti-proliferative and pro-apoptotic effects of (-)-epigallocatechin-3-gallate encapsulated in chitosan nanoparticles on human melanoma cell growth both in vitro and in vivo.
    Nanomedicine : nanotechnology, biology, and medicine, 2014, Volume: 10, Issue:8

    Topics: Animals; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Chitosan; Humans; Male; Melanoma; Mice; Mice, Nude; Nanoparticles; Nanotechnology; Xenograft Model Antitumor Assays

2014
Epigallocatechingallate inhibits migration of human uveal melanoma cells via downregulation of matrix metalloproteinase-2 activity and ERK1/2 pathway.
    BioMed research international, 2014, Volume: 2014

    Topics: Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Melanoma; Phosphorylation; Uveal Neoplasms

2014
67-kDa laminin receptor-dependent protein phosphatase 2A (PP2A) activation elicits melanoma-specific antitumor activity overcoming drug resistance.
    The Journal of biological chemistry, 2014, Nov-21, Volume: 289, Issue:47

    Topics: Animals; Blotting, Western; Catechin; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; DNA-Binding Proteins; Drug Resistance, Neoplasm; Enzyme Activation; Female; Histone Chaperones; Humans; Indoles; Melanoma; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Microscopy, Confocal; Mutation; Neurofibromin 2; Protein Phosphatase 2; Proto-Oncogene Proteins B-raf; Receptors, Laminin; RNA Interference; Sulfonamides; TOR Serine-Threonine Kinases; Transcription Factors; Xenograft Model Antitumor Assays

2014
Epigallocatechin-3-O-gallate up-regulates microRNA-let-7b expression by activating 67-kDa laminin receptor signaling in melanoma cells.
    Scientific reports, 2016, Jan-12, Volume: 6

    Topics: Animals; Catechin; Cell Line, Tumor; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HMGA2 Protein; Humans; Melanoma; Mice; MicroRNAs; Protein Phosphatase 2; Receptors, Laminin; Ribosomal Proteins; Signal Transduction

2016
Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Animals; Antineoplastic Agents, Phytogenic; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; MAP Kinase Kinase Kinases; Melanoma; Mice, Inbred BALB C; Molecular Docking Simulation; Neoplasm Invasiveness; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Binding; Protein Conformation; Signal Transduction; Skin Neoplasms; Structure-Activity Relationship; TNF Receptor-Associated Factor 6; Transfection; Tumor Burden; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination

2016
Inhibition of invasion and up-regulation of E-cadherin expression in human malignant melanoma cell line A375 by (-)-epigallocatechin-3-gallate.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2008, Volume: 28, Issue:3

    Topics: Blotting, Western; Cadherins; Catechin; Cell Adhesion; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Neoplasm Invasiveness; Neoplasm Metastasis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Time Factors; Up-Regulation

2008
(-)-Epigallocatechin-3-gallate (EGCG) sensitizes melanoma cells to interferon induced growth inhibition in a mouse model of human melanoma.
    Cell cycle (Georgetown, Tex.), 2009, Jul-01, Volume: 8, Issue:13

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; fas Receptor; Humans; Interferon-alpha; Melanoma; Mice; Mice, Nude; NF-kappa B; Proliferating Cell Nuclear Antigen; Tea; Xenograft Model Antitumor Assays

2009
New life for an "old" drink.
    Cell cycle (Georgetown, Tex.), 2009, Jul-01, Volume: 8, Issue:13

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Catechin; Cell Cycle; Drug Therapy, Combination; Humans; Melanoma; Mice; Signal Transduction; Tea

2009
Inhibitory effects of epigallocatechin-3 gallate, a polyphenol in green tea, on tumor-associated endothelial cells and endothelial progenitor cells.
    Cancer science, 2009, Volume: 100, Issue:10

    Topics: Animals; Anticarcinogenic Agents; Blotting, Western; Catechin; Cell Line, Tumor; Cell Movement; Down-Regulation; Endothelial Cells; Flavonoids; Flow Cytometry; Gene Expression; Humans; Matrix Metalloproteinase 9; Melanoma; Mice; Microvessels; Neovascularization, Pathologic; Phenols; Polyphenols; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Tea; Xenograft Model Antitumor Assays

2009
EGCG enhances TRAIL-mediated apoptosis in human melanoma A375 cell line.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2009, Volume: 29, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 8; Catechin; Cell Line, Tumor; Drug Synergism; Humans; Melanoma; Receptors, TNF-Related Apoptosis-Inducing Ligand; Skin Neoplasms; TNF-Related Apoptosis-Inducing Ligand

2009
Anti-melanoma effects of vorinostat in combination with polyphenolic antioxidant (-)-epigallocatechin-3-gallate (EGCG).
    Pharmaceutical research, 2010, Volume: 27, Issue:6

    Topics: Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; eIF-2 Kinase; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Melanoma; NF-kappa B; Vorinostat

2010
Green tea polyphenol epigallocatechin-3-gallate suppresses melanoma growth by inhibiting inflammasome and IL-1β secretion.
    Biochemical and biophysical research communications, 2011, Oct-28, Volume: 414, Issue:3

    Topics: Animals; Antineoplastic Agents; Camellia sinensis; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Humans; Inflammation; Interleukin-1beta; Melanoma; Mice; Mice, Nude; Polyphenols; Skin Neoplasms

2011
Green tea catechins reduce invasive potential of human melanoma cells by targeting COX-2, PGE2 receptors and epithelial-to-mesenchymal transition.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Catechin; Celecoxib; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Humans; Melanoma; Neoplasm Invasiveness; NF-kappa B; Pyrazoles; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides; Tea; Tetradecanoylphorbol Acetate; Transcription Factor RelA

2011
Antitumor activity of the tea polyphenol epigallocatechin-3-gallate encapsulated in targeted vesicles after intravenous administration.
    Nanomedicine (London, England), 2013, Volume: 8, Issue:2

    Topics: Administration, Intravenous; Animals; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Female; Humans; Melanoma; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Tea; Xenograft Model Antitumor Assays

2013
Oxidation of indole-3-acetic acid by horseradish peroxidase induces apoptosis in G361 human melanoma cells.
    Cellular signalling, 2004, Volume: 16, Issue:1

    Topics: Antioxidants; Apoptosis; Ascorbic Acid; Caspases; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Free Radicals; Horseradish Peroxidase; Humans; Indoleacetic Acids; JNK Mitogen-Activated Protein Kinases; Melanoma; Mitochondria; Mitogen-Activated Protein Kinases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Prodrugs; Proteins

2004
Anti-proliferative and proapoptotic effects of (-)-epigallocatechin-3-gallate on human melanoma: possible implications for the chemoprevention of melanoma.
    International journal of cancer, 2005, Apr-20, Volume: 114, Issue:4

    Topics: Agar; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 7; Caspase 9; Caspases; Catechin; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Separation; Cell Survival; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Down-Regulation; Flow Cytometry; Humans; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; Ki-67 Antigen; Melanocytes; Melanoma; Membrane Potentials; Mitochondria; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Time Factors

2005
(-)-Epigallocatechin-3-gallate, a polyphenolic compound from green tea, inhibits fibroblast adhesion and migration through multiple mechanisms.
    Journal of cellular biochemistry, 2005, Sep-01, Volume: 96, Issue:1

    Topics: Actins; Antibodies; Catechin; Cell Adhesion; Cell Line; Cell Line, Tumor; Cell Movement; Coculture Techniques; Cytoskeleton; Extracellular Matrix; Extracellular Matrix Proteins; Fibroblasts; Humans; Hydrogen Peroxide; Integrin alpha2beta1; Matrix Metalloproteinase Inhibitors; Melanoma; Tea

2005
Effect of liposome encapsulation of tea catechins on their accumulation in basal cell carcinomas.
    Journal of dermatological science, 2006, Volume: 42, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Basal Cell; Catechin; Cell Line, Tumor; Deoxycholic Acid; Drug Delivery Systems; Ethanol; Female; Humans; Liposomes; Melanoma; Mice; Mice, Inbred BALB C; Tea

2006
Can green tea protect against not only sunburn but also melanoma?
    Chinese medical journal, 2006, Jun-20, Volume: 119, Issue:12

    Topics: Catechin; Melanoma; Nitric Oxide; Skin Neoplasms; Sunburn; Tea; Ultraviolet Rays

2006